Vitamin K1 alleviates streptozotocin-induced type 1 diabetes by mitigating free radical stress, as well as inhibiting NF-κB activation and iNOS expression in rat pancreas

Nutrition

Volumn 31, Issue 1, 2015, Pages 214-222

  Varsha, M K N Sai ^a   Thiagarajan, R ^a   Manikandan, R ^b   Dhanasekaran, G ^b  

^a SASTRA UNIVERSITY   (India)

^b UNIVERSITY OF MADRAS   (India)

Author keywords

Aldose reductase; Antioxidant; Diabetes; Oxidative stress; Pancreas; Type 1 diabetes; Vitamin K

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATASE (CALCIUM); ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ALDEHYDE REDUCTASE; FREE RADICAL; GLUCOSE; GLYCOSYLATED HEMOGLOBIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INSULIN; PHYTOMENADIONE; STREPTOZOCIN; ANTIDIABETIC AGENT; ANTIOXIDANT; GLUCOSE BLOOD LEVEL; HEMOGLOBIN; NOS2 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL DEATH; CELL PROLIFERATION; CELL PROTECTION; CELL REGENERATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; ENZYME INHIBITION; GLUCOSE BLOOD LEVEL; HEMOGLOBIN BLOOD LEVEL; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; MALE; NONHUMAN; OXIDATIVE STRESS; PANCREAS; PANCREAS ISLET; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; TREATMENT DURATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; CHEMICALLY INDUCED; CYTOLOGY; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; SECRETION (PROCESS); WISTAR RAT;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

ANIMALS; ANTIOXIDANTS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DOSE-RESPONSE RELATIONSHIP, DRUG; HEMOGLOBINS; HYPOGLYCEMIC AGENTS; INSULIN; ISLETS OF LANGERHANS; MALE; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; PANCREAS; RATS; RATS, WISTAR; STREPTOZOCIN; VITAMIN K 1;

EID: 84922227387     PISSN: 08999007     EISSN: 18731244     Source Type: Journal    
DOI: 10.1016/j.nut.2014.05.012     Document Type: Article

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