Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine export

Molecular Metabolism

Volumn 5, Issue 7, 2016, Pages 538-551

  White, Phillip J ^a   Lapworth, Amanda L ^b   An, Jie ^a   Wang, Liping ^a   McGarrah, Robert W ^a   Stevens, Robert D ^a   Ilkayeva, Olga ^a   George, Tabitha ^a   Muehlbauer, Michael J ^a   Bain, James R ^a   Trimmer, Jeff K ^b   Brosnan, M Julia ^b   Rolph, Timothy P ^b   Newgard, Christopher B ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PFIZER INC   (United States)

Author keywords

BCAA; Insulin sensitivity; Metabolism; Obesity

Indexed keywords

2 OXOISOVALERATE DEHYDROGENASE (LIPOAMIDE); ACYL COENZYME A; ACYL GLYCINE; AMINO ACID DERIVATIVE; BRANCHED CHAIN AMINO ACID; FATTY ACID DERIVATIVE; ISOLEUCINE; LEUCINE; UNCLASSIFIED DRUG; VALINE;

AMINO ACID METABOLISM; AMINO ACID TRANSPORT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATABOLISM; CONTROLLED STUDY; DIABETES MELLITUS; DIET RESTRICTION; ENERGY BALANCE; ENZYME ACTIVITY; FATTY ACID OXIDATION; FATTY ACID TRANSPORT; GLUCOSE METABOLISM; HYPERINSULINEMIC-EUGLYCEMIC CLAMP TECHNIQUE; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID METABOLISM; LIPID OXIDATION; LOW FAT DIET; MALE; METABOLIC DISORDER; METABOLITE; NONHUMAN; OBESITY; PRIORITY JOURNAL; RAT; RODENT MODEL; ZUCKER FATTY RAT; ZUCKER LEAN RAT;

EID: 84964584453     PISSN: None     EISSN: 22128778     Source Type: Journal    
DOI: 10.1016/j.molmet.2016.04.006     Document Type: Article

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