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Volumn 58, Issue 10, 2015, Pages 2324-2335

Impact of combined resistance and aerobic exercise training on branched-chain amino acid turnover, glycine metabolism and insulin sensitivity in overweight humans

Author keywords

Branched chain amino acids; Exercise; Insulin resistance; Metabolomics; Obesity; Protein

Indexed keywords

2 OXOACID; 4 HYDROXYBENZOIC ACID; ACYLCARNITINE; ADIPONECTIN; ARGININE; BRANCHED CHAIN AMINO ACID; C PEPTIDE; CITRULLINE; GASTRIC INHIBITORY POLYPEPTIDE; GENTISIC ACID; GLUCOSE; GLUTAMIC ACID; GLUTAMINE; GLYCINE; HYDROQUINONE; INSULIN; LEPTIN; LEUCINE; PHENYLALANINE; SERINE; TYROSINE; GLUCOSE BLOOD LEVEL;

EID: 84942194346     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-015-3705-6     Document Type: Article
Times cited : (109)

References (45)
  • 1
    • 84860439210 scopus 로고    scopus 로고
    • Interplay between lipids and branched-chain amino acids in development of insulin resistance
    • Newgard CB (2012) Interplay between lipids and branched-chain amino acids in development of insulin resistance. Cell Metab 15:606–614
    • (2012) Cell Metab , vol.15 , pp. 606-614
    • Newgard, C.B.1
  • 2
    • 0014669160 scopus 로고
    • Plasma amino acid levels and insulin secretion in obesity
    • COI: 1:CAS:528:DyaF1MXlt1Wltbw%3D, PID: 5809519
    • Felig P, Marliss E, Cahill GF (1969) Plasma amino acid levels and insulin secretion in obesity. N Engl J Med 281:811–816
    • (1969) N Engl J Med , vol.281 , pp. 811-816
    • Felig, P.1    Marliss, E.2    Cahill, G.F.3
  • 3
    • 0023904645 scopus 로고
    • Plasma amino acids and insulin levels in obesity: response to carbohydrate intake and tryptophan supplements
    • COI: 1:CAS:528:DyaL1cXktlOjtLs%3D, PID: 3290625
    • Caballero B, Finer N, Wurtman RJ (1988) Plasma amino acids and insulin levels in obesity: response to carbohydrate intake and tryptophan supplements. Metabolism 37:672–676
    • (1988) Metabolism , vol.37 , pp. 672-676
    • Caballero, B.1    Finer, N.2    Wurtman, R.J.3
  • 4
    • 0030851478 scopus 로고    scopus 로고
    • Protein metabolism in human obesity: relationship with glucose and lipid metabolism and with visceral adipose tissue
    • COI: 1:CAS:528:DyaK2sXltFKhsL8%3D, PID: 9253333
    • Solini A, Bonora E, Bonadonna R, Castellino P, DeFronzo RA (1997) Protein metabolism in human obesity: relationship with glucose and lipid metabolism and with visceral adipose tissue. J Clin Endocrinol Metab 82:2552–2558
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2552-2558
    • Solini, A.1    Bonora, E.2    Bonadonna, R.3    Castellino, P.4    DeFronzo, R.A.5
  • 5
    • 63449111894 scopus 로고    scopus 로고
    • A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance
    • COI: 1:CAS:528:DC%2BD1MXlsFyru78%3D, PID: 19356713
    • Newgard CB, An J, Bain JR et al (2009) A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Cell Metab 9:311–326
    • (2009) Cell Metab , vol.9 , pp. 311-326
    • Newgard, C.B.1    An, J.2    Bain, J.R.3
  • 6
    • 77949267650 scopus 로고    scopus 로고
    • Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men
    • COI: 1:CAS:528:DC%2BC3cXis1Cmu7Y%3D, PID: 20076942
    • Tai ES, Tan ML, Stevens RD et al (2010) Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men. Diabetologia 53:757–767
    • (2010) Diabetologia , vol.53 , pp. 757-767
    • Tai, E.S.1    Tan, M.L.2    Stevens, R.D.3
  • 7
    • 69549097700 scopus 로고    scopus 로고
    • Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women
    • COI: 1:CAS:528:DC%2BD1MXht1agtr3L, PID: 19502541
    • Huffman KM, Shah SH, Stevens RD et al (2009) Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women. Diabetes Care 32:1678–1683
    • (2009) Diabetes Care , vol.32 , pp. 1678-1683
    • Huffman, K.M.1    Shah, S.H.2    Stevens, R.D.3
  • 8
    • 84856728068 scopus 로고    scopus 로고
    • Branched-chain amino acid levels are associated with improvement in insulin resistance with weight loss
    • COI: 1:CAS:528:DC%2BC3MXhs1yntbfO, PID: 22065088
    • Shah SH, Crosslin DR, Haynes CS et al (2012) Branched-chain amino acid levels are associated with improvement in insulin resistance with weight loss. Diabetologia 55:321–330
    • (2012) Diabetologia , vol.55 , pp. 321-330
    • Shah, S.H.1    Crosslin, D.R.2    Haynes, C.S.3
  • 9
    • 79953737332 scopus 로고    scopus 로고
    • Metabolite profiles and the risk of developing diabetes
    • PID: 21423183
    • Wang TJ, Larson MG, Vasan RS et al (2011) Metabolite profiles and the risk of developing diabetes. Nat Med 17:448–453
    • (2011) Nat Med , vol.17 , pp. 448-453
    • Wang, T.J.1    Larson, M.G.2    Vasan, R.S.3
  • 10
    • 37449020075 scopus 로고    scopus 로고
    • Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
    • COI: 1:CAS:528:DC%2BD1cXnsFSnsQ%3D%3D, PID: 18177724
    • Koves TR, Ussher JR, Noland RC et al (2008) Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance. Cell Metab 7:45–56
    • (2008) Cell Metab , vol.7 , pp. 45-56
    • Koves, T.R.1    Ussher, J.R.2    Noland, R.C.3
  • 11
    • 39749147110 scopus 로고    scopus 로고
    • Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes
    • COI: 1:CAS:528:DC%2BD1cXitlGnurg%3D, PID: 18200017
    • Muoio DM, Newgard CB (2008) Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes. Nat Rev Mol Cell Biol 9:193–205
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 193-205
    • Muoio, D.M.1    Newgard, C.B.2
  • 12
    • 0035856949 scopus 로고    scopus 로고
    • Insulin signalling and the regulation of glucose and lipid metabolism
    • COI: 1:CAS:528:DC%2BD38Xhtlylsg%3D%3D, PID: 11742412
    • Saltiel AR, Kahn CR (2001) Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414:799–806
    • (2001) Nature , vol.414 , pp. 799-806
    • Saltiel, A.R.1    Kahn, C.R.2
  • 13
    • 0141531039 scopus 로고    scopus 로고
    • Targeting the metabolic syndrome with exercise: evidence from the HERITAGE Family Study
    • COI: 1:CAS:528:DC%2BD3sXnslaku7Y%3D, PID: 14523308
    • Katzmarzyk PT, Leon AS, Wilmore JH et al (2003) Targeting the metabolic syndrome with exercise: evidence from the HERITAGE Family Study. Med Sci Sports Exerc 35:1703–1709
    • (2003) Med Sci Sports Exerc , vol.35 , pp. 1703-1709
    • Katzmarzyk, P.T.1    Leon, A.S.2    Wilmore, J.H.3
  • 14
    • 84873436414 scopus 로고    scopus 로고
    • Mitochondria express enhanced quality as well as quantity in association with aerobic fitness across recreationally active individuals up to elite athletes
    • COI: 1:CAS:528:DC%2BC3sXktV2qsLw%3D, PID: 23221957
    • Jacobs RA, Lundby C (2013) Mitochondria express enhanced quality as well as quantity in association with aerobic fitness across recreationally active individuals up to elite athletes. J Appl Physiol 114:344–350
    • (2013) J Appl Physiol , vol.114 , pp. 344-350
    • Jacobs, R.A.1    Lundby, C.2
  • 15
    • 84876251802 scopus 로고    scopus 로고
    • Nine months of combined training improves ex vivo skeletal muscle metabolism in individuals with type 2 diabetes
    • COI: 1:CAS:528:DC%2BC3sXmtFehtLY%3D, PID: 23463651
    • Sparks LM, Johannsen NM, Church TS et al (2013) Nine months of combined training improves ex vivo skeletal muscle metabolism in individuals with type 2 diabetes. J Clin Endocrinol Metab 98:1694–1702
    • (2013) J Clin Endocrinol Metab , vol.98 , pp. 1694-1702
    • Sparks, L.M.1    Johannsen, N.M.2    Church, T.S.3
  • 16
    • 84863393071 scopus 로고    scopus 로고
    • Muscle protein synthesis in response to nutrition and exercise
    • COI: 1:CAS:528:DC%2BC38XkslSmsrw%3D, PID: 22289911
    • Atherton PJ, Smith K (2012) Muscle protein synthesis in response to nutrition and exercise. J Physiol 590:1049–1057
    • (2012) J Physiol , vol.590 , pp. 1049-1057
    • Atherton, P.J.1    Smith, K.2
  • 17
    • 0025129387 scopus 로고
    • Tandem mass spectrometry: a new method for acylcarnitine profiling with potential for neonatal screening for inborn errors of metabolism
    • COI: 1:CAS:528:DyaK3MXltV2ksrc%3D, PID: 2122093
    • Millington DS, Kodo N, Norwood DL, Roe CR (1990) Tandem mass spectrometry: a new method for acylcarnitine profiling with potential for neonatal screening for inborn errors of metabolism. J Inherit Metab Dis 13:321–324
    • (1990) J Inherit Metab Dis , vol.13 , pp. 321-324
    • Millington, D.S.1    Kodo, N.2    Norwood, D.L.3    Roe, C.R.4
  • 18
    • 84879217970 scopus 로고    scopus 로고
    • Quantification of branched-chain keto acids in tissue by ultra fast liquid chromatography-mass spectrometry
    • COI: 1:CAS:528:DC%2BC3sXhtVyqtLnE, PID: 23684523
    • Olson KC, Chen G, Lynch CJ (2013) Quantification of branched-chain keto acids in tissue by ultra fast liquid chromatography-mass spectrometry. Anal Biochem 439:116–122
    • (2013) Anal Biochem , vol.439 , pp. 116-122
    • Olson, K.C.1    Chen, G.2    Lynch, C.J.3
  • 19
    • 0027334865 scopus 로고
    • Measurement of 15N enrichment in multiple amino acids and urea in a single analysis by gas chromatography/mass spectrometry
    • COI: 1:CAS:528:DyaK2cXis12hsA%3D%3D, PID: 8399400
    • Patterson BW, Carraro F, Wolfe RR (1993) Measurement of 15N enrichment in multiple amino acids and urea in a single analysis by gas chromatography/mass spectrometry. Biol Mass Spectrom 22:518–523
    • (1993) Biol Mass Spectrom , vol.22 , pp. 518-523
    • Patterson, B.W.1    Carraro, F.2    Wolfe, R.R.3
  • 21
    • 18144366554 scopus 로고    scopus 로고
    • LC/MS/MS method for quantitative determination of long-chain fatty acyl-CoAs
    • COI: 1:CAS:528:DC%2BD2MXisFOnsro%3D, PID: 15859607
    • Magnes C, Sinner FM, Regittnig W, Pieber TR (2005) LC/MS/MS method for quantitative determination of long-chain fatty acyl-CoAs. Anal Chem 77:2889–2894
    • (2005) Anal Chem , vol.77 , pp. 2889-2894
    • Magnes, C.1    Sinner, F.M.2    Regittnig, W.3    Pieber, T.R.4
  • 22
    • 41949105208 scopus 로고    scopus 로고
    • Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling
    • Ferrara CT, Wang P, Neto EC et al (2008) Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling. PLoS Genet 4:e1000034
    • (2008) PLoS Genet , vol.e1000034 , pp. 4
    • Ferrara, C.T.1    Wang, P.2    Neto, E.C.3
  • 23
    • 41849099558 scopus 로고    scopus 로고
    • Novel isolation procedure for short-, medium-, and long-chain acyl-coenzyme A esters from tissue
    • COI: 1:CAS:528:DC%2BD1cXkslejtro%3D, PID: 18355435
    • Minkler PE, Kerner J, Ingalls ST, Hoppel CL (2008) Novel isolation procedure for short-, medium-, and long-chain acyl-coenzyme A esters from tissue. Anal Biochem 376:275–276
    • (2008) Anal Biochem , vol.376 , pp. 275-276
    • Minkler, P.E.1    Kerner, J.2    Ingalls, S.T.3    Hoppel, C.L.4
  • 24
    • 0016199722 scopus 로고
    • Glycogen, glycolytic intermediates and high-energy phosphates determined in biopsy samples of musculus quadriceps femoris of man at rest. Methods and variance of values
    • COI: 1:CAS:528:DyaE2cXkslCgtrw%3D, PID: 4852173
    • Harris RC, Hultman E, Nordesjo LO (1974) Glycogen, glycolytic intermediates and high-energy phosphates determined in biopsy samples of musculus quadriceps femoris of man at rest. Methods and variance of values. Scand J Clin Lab Invest 33:109–120
    • (1974) Scand J Clin Lab Invest , vol.33 , pp. 109-120
    • Harris, R.C.1    Hultman, E.2    Nordesjo, L.O.3
  • 25
    • 0033452842 scopus 로고    scopus 로고
    • An integrated method for spectrum extraction and compound identification from gas chromatography/mass spectrometry data
    • COI: 1:CAS:528:DyaK1MXkvFert7Y%3D
    • Stein SE (1999) An integrated method for spectrum extraction and compound identification from gas chromatography/mass spectrometry data. J Am Soc Mass Spectrom 10:770–781
    • (1999) J Am Soc Mass Spectrom , vol.10 , pp. 770-781
    • Stein, S.E.1
  • 26
    • 0032991929 scopus 로고    scopus 로고
    • Deconvolution gas chromatography/mass spectrometry of urinary organic acids--potential for pattern recognition and automated identification of metabolic disorders
    • COI: 1:CAS:528:DyaK1MXhtlKntrw%3D, PID: 10097403
    • Halket JM, Przyborowska A, Stein SE et al (1999) Deconvolution gas chromatography/mass spectrometry of urinary organic acids--potential for pattern recognition and automated identification of metabolic disorders. Rapid Commun Mass Spectrom 13:279–284
    • (1999) Rapid Commun Mass Spectrom , vol.13 , pp. 279-284
    • Halket, J.M.1    Przyborowska, A.2    Stein, S.E.3
  • 27
    • 0022294449 scopus 로고
    • Use of reciprocal pool specific activities to model leucine metabolism in humans
    • COI: 1:CAS:528:DyaL28XkvFWgtg%3D%3D, PID: 4083346
    • Schwenk WF, Beaufrere B, Haymond MW (1985) Use of reciprocal pool specific activities to model leucine metabolism in humans. Am J Physiol 249:E646–E650
    • (1985) Am J Physiol , vol.249 , pp. E646-E650
    • Schwenk, W.F.1    Beaufrere, B.2    Haymond, M.W.3
  • 28
    • 84919973700 scopus 로고    scopus 로고
    • Metabolite signatures of exercise training in human skeletal muscle relate to mitochondrial remodelling and cardiometabolic fitness
    • COI: 1:CAS:528:DC%2BC2cXhtlantbvF, PID: 25091629
    • Huffman KM, Koves TR, Hubal MJ et al (2014) Metabolite signatures of exercise training in human skeletal muscle relate to mitochondrial remodelling and cardiometabolic fitness. Diabetologia 57:2282–2295
    • (2014) Diabetologia , vol.57 , pp. 2282-2295
    • Huffman, K.M.1    Koves, T.R.2    Hubal, M.J.3
  • 29
    • 77953667219 scopus 로고    scopus 로고
    • Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events
    • COI: 1:CAS:528:DC%2BC3cXmvF2mu7o%3D, PID: 20173117
    • Shah SH, Bain JR, Muehlbauer MJ et al (2010) Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events. Circ Cardiovasc Genet 3:207–U233
    • (2010) Circ Cardiovasc Genet , vol.3 , pp. 207-U233
    • Shah, S.H.1    Bain, J.R.2    Muehlbauer, M.J.3
  • 30
    • 84879550459 scopus 로고    scopus 로고
    • Branched chain amino acids are novel biomarkers for discrimination of metabolic wellness
    • COI: 1:CAS:528:DC%2BC3sXhvFait78%3D, PID: 23375209
    • Batch BC, Shah SH, Newgard CB et al (2013) Branched chain amino acids are novel biomarkers for discrimination of metabolic wellness. Metabolism 62:961–969
    • (2013) Metabolism , vol.62 , pp. 961-969
    • Batch, B.C.1    Shah, S.H.2    Newgard, C.B.3
  • 31
    • 37149027613 scopus 로고    scopus 로고
    • Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism
    • COI: 1:CAS:528:DC%2BD2sXhsVGls7rO, PID: 17925455
    • She P, Van Horn C, Reid T, Hutson SM, Cooney RN, Lynch CJ (2007) Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism. Am J Physiol Endocrinol Metab 293:E1552–E1563
    • (2007) Am J Physiol Endocrinol Metab , vol.293 , pp. E1552-E1563
    • She, P.1    Van Horn, C.2    Reid, T.3    Hutson, S.M.4    Cooney, R.N.5    Lynch, C.J.6
  • 32
    • 0028914883 scopus 로고
    • Increased rates of muscle protein turnover and amino acid transport after resistance exercise in humans
    • COI: 1:CAS:528:DyaK2MXkslKiu7g%3D, PID: 7900797
    • Biolo G, Maggi SP, Williams BD, Tipton KD, Wolfe RR (1995) Increased rates of muscle protein turnover and amino acid transport after resistance exercise in humans. Am J Physiol 268:E514–E520
    • (1995) Am J Physiol , vol.268 , pp. E514-E520
    • Biolo, G.1    Maggi, S.P.2    Williams, B.D.3    Tipton, K.D.4    Wolfe, R.R.5
  • 33
    • 0036906223 scopus 로고    scopus 로고
    • Resistance-training-induced adaptations in skeletal muscle protein turnover in the fed state
    • COI: 1:CAS:528:DC%2BD38XpsFCksbw%3D, PID: 12489923
    • Phillips SM, Parise G, Roy BD, Tipton KD, Wolfe RR, Tamopolsky MA (2002) Resistance-training-induced adaptations in skeletal muscle protein turnover in the fed state. Can J Physiol Pharmacol 80:1045–1053
    • (2002) Can J Physiol Pharmacol , vol.80 , pp. 1045-1053
    • Phillips, S.M.1    Parise, G.2    Roy, B.D.3    Tipton, K.D.4    Wolfe, R.R.5    Tamopolsky, M.A.6
  • 34
    • 84883319463 scopus 로고    scopus 로고
    • Effects of high-protein diets on fat-free mass and muscle protein synthesis following weight loss: a randomized controlled trial
    • COI: 1:CAS:528:DC%2BC3sXhsVaitLvI, PID: 23739654
    • Pasiakos SM, Cao JJ, Margolis LM et al (2013) Effects of high-protein diets on fat-free mass and muscle protein synthesis following weight loss: a randomized controlled trial. FASEB J 27:3837–3847
    • (2013) FASEB J , vol.27 , pp. 3837-3847
    • Pasiakos, S.M.1    Cao, J.J.2    Margolis, L.M.3
  • 35
    • 77951232682 scopus 로고    scopus 로고
    • Adipose tissue branched chain amino acid (BCAA) metabolism modulates circulating BCAA levels
    • COI: 1:CAS:528:DC%2BC3cXktFGlsbc%3D, PID: 20093359
    • Herman MA, She P, Peroni OD et al (2010) Adipose tissue branched chain amino acid (BCAA) metabolism modulates circulating BCAA levels. J Biol Chem 285:11348–11356
    • (2010) J Biol Chem , vol.285 , pp. 11348-11356
    • Herman, M.A.1    She, P.2    Peroni, O.D.3
  • 36
    • 25844432311 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma co-activator 1 alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency
    • COI: 1:CAS:528:DC%2BD2MXhtVensb7M, PID: 16079133
    • Koves TR, Li P, An J et al (2005) Peroxisome proliferator-activated receptor-gamma co-activator 1 alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency. J Biol Chem 280:33588–33598
    • (2005) J Biol Chem , vol.280 , pp. 33588-33598
    • Koves, T.R.1    Li, P.2    An, J.3
  • 37
    • 84875475979 scopus 로고    scopus 로고
    • A lipidomics analysis of the relationship between dietary fatty acid composition and insulin sensitivity in young adults
    • COI: 1:CAS:528:DC%2BC3sXpvFCktbw%3D, PID: 23238293
    • Kien CL, Bunn JY, Poynter ME et al (2013) A lipidomics analysis of the relationship between dietary fatty acid composition and insulin sensitivity in young adults. Diabetes 62:1054–1063
    • (2013) Diabetes , vol.62 , pp. 1054-1063
    • Kien, C.L.1    Bunn, J.Y.2    Poynter, M.E.3
  • 38
    • 57049142094 scopus 로고    scopus 로고
    • Metabolic flexibility and insulin resistance
    • COI: 1:CAS:528:DC%2BD1cXhsVWkurbK, PID: 18765680
    • Galgani JE, Moro C, Ravussin E (2008) Metabolic flexibility and insulin resistance. Am J Physiol Endocrinol Metab 295:E1009–E1017
    • (2008) Am J Physiol Endocrinol Metab , vol.295 , pp. E1009-E1017
    • Galgani, J.E.1    Moro, C.2    Ravussin, E.3
  • 39
    • 79951715433 scopus 로고    scopus 로고
    • Exercise-induced changes in metabolic intermediates, hormones, and inflammatory markers associated with improvements in insulin sensitivity
    • PID: 20921216
    • Huffman KM, Slentz CA, Bateman LA et al (2011) Exercise-induced changes in metabolic intermediates, hormones, and inflammatory markers associated with improvements in insulin sensitivity. Diabetes Care 34:174–176
    • (2011) Diabetes Care , vol.34 , pp. 174-176
    • Huffman, K.M.1    Slentz, C.A.2    Bateman, L.A.3
  • 40
    • 0343114366 scopus 로고    scopus 로고
    • Quantitative analysis of urinary acylglycines for the diagnosis of beta-oxidation defects using GC-NCI-MS
    • COI: 1:CAS:528:DC%2BD3cXot1ar, PID: 10708405
    • Costa CG, Guerand WS, Struys EA et al (2000) Quantitative analysis of urinary acylglycines for the diagnosis of beta-oxidation defects using GC-NCI-MS. J Pharm Biomed Anal 21:1215–1224
    • (2000) J Pharm Biomed Anal , vol.21 , pp. 1215-1224
    • Costa, C.G.1    Guerand, W.S.2    Struys, E.A.3
  • 41
    • 82755184864 scopus 로고    scopus 로고
    • The footprints of gut microbial-mammalian co-metabolism
    • COI: 1:CAS:528:DC%2BC3MXhtlGgur7J, PID: 21970572
    • Zheng X, Xie G, Zhao A et al (2011) The footprints of gut microbial-mammalian co-metabolism. J Proteome Res 10:5512–5522
    • (2011) J Proteome Res , vol.10 , pp. 5512-5522
    • Zheng, X.1    Xie, G.2    Zhao, A.3
  • 42
    • 84867453026 scopus 로고    scopus 로고
    • Metabolomics view on gut microbiome modulation by polyphenol-rich foods
    • COI: 1:CAS:528:DC%2BC38Xht1ahu7jO, PID: 22905879
    • Moco S, Martin FP, Rezzi S (2012) Metabolomics view on gut microbiome modulation by polyphenol-rich foods. J Proteome Res 11:4781–4790
    • (2012) J Proteome Res , vol.11 , pp. 4781-4790
    • Moco, S.1    Martin, F.P.2    Rezzi, S.3
  • 43
    • 84883478660 scopus 로고    scopus 로고
    • Gut microbiota from twins discordant for obesity modulate metabolism in mice
    • PID: 24009397
    • Ridaura VK, Faith JJ, Rey FE et al (2013) Gut microbiota from twins discordant for obesity modulate metabolism in mice. Science 341:1241214
    • (2013) Science , vol.341 , pp. 1241214
    • Ridaura, V.K.1    Faith, J.J.2    Rey, F.E.3
  • 44
    • 0031978984 scopus 로고    scopus 로고
    • Exercise, glucose transport, and insulin sensitivity
    • COI: 1:CAS:528:DyaK1cXhtFKqs74%3D, PID: 9509261
    • Goodyear LJ, Kahn BB (1998) Exercise, glucose transport, and insulin sensitivity. Annu Rev Med 49:235–261
    • (1998) Annu Rev Med , vol.49 , pp. 235-261
    • Goodyear, L.J.1    Kahn, B.B.2
  • 45
    • 84893117372 scopus 로고    scopus 로고
    • BMI, RQ, diabetes, and sex affect the relationships between amino acids and clamp measures of insulin action in humans
    • PID: 24130332
    • Thalacker-Mercer AE, Ingram KH, Guo F, Ilkayeva O, Newgard CB, Garvey WT (2014) BMI, RQ, diabetes, and sex affect the relationships between amino acids and clamp measures of insulin action in humans. Diabetes 63:791–800
    • (2014) Diabetes , vol.63 , pp. 791-800
    • Thalacker-Mercer, A.E.1    Ingram, K.H.2    Guo, F.3    Ilkayeva, O.4    Newgard, C.B.5    Garvey, W.T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.