메뉴 건너뛰기




Volumn 439, Issue 2, 2013, Pages 116-122

Quantification of branched-chain keto acids in tissue by ultra fast liquid chromatography-mass spectrometry

Author keywords

2 Keto 3 methylvalerate; 2 Ketoisocaproate; 2 Ketoisovalerate; Branched chain keto acid; Maple syrup urine disease; Spectrometry; Ultra fast liquid chromatography mass

Indexed keywords

HIGH PRESSURE LIQUID CHROMATOGRAPHY; HISTOLOGY; LIQUIDS; MASS SPECTROMETRY; POLYMER BLENDS; SPECTROMETRY; TISSUE;

EID: 84879217970     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2013.05.002     Document Type: Article
Times cited : (30)

References (41)
  • 1
    • 84555195141 scopus 로고    scopus 로고
    • Hypothalamic leucine metabolism regulates liver glucose production
    • Y. Su, T.K. Lam, W. He, A. Pocai, J. Bryan, L. Aguilar-Bryan, R. Gutierrez-Juarez, Hypothalamic leucine metabolism regulates liver glucose production, Diabetes 61 (2012) 85-93.
    • (2012) Diabetes , vol.61 , pp. 85-93
    • Su, Y.1    Lam, T.K.2    He, W.3    Pocai, A.4    Bryan, J.L.R.5
  • 4
    • 84857031834 scopus 로고    scopus 로고
    • Leucine as a pharmaconutrient in health and disease
    • L.J. van Loon, Leucine as a pharmaconutrient in health and disease, Curr. Opin. Clin. Nutr. Metab. Care 15 (2012) 71-77.
    • (2012) Curr. Opin. Clin. Nutr. Metab. Care , vol.15 , pp. 71-77
    • Van Loon, L.J.1
  • 5
    • 84862282554 scopus 로고    scopus 로고
    • Emerging perspectives on essential amino acid metabolism in obesity and the insulin-resistant state
    • S.H. Adams, Emerging perspectives on essential amino acid metabolism in obesity and the insulin-resistant state, Adv. Nutr. 2 (2011) 445-456.
    • (2011) Adv. Nutr. , vol.2 , pp. 445-456
    • Adams, S.H.1
  • 6
    • 0025597875 scopus 로고
    • Elusive proximal signals of beta-cells for insulin secretion
    • M.J. MacDonald, Elusive proximal signals of beta-cells for insulin secretion, Diabetes 39 (1990) 1461-1466.
    • (1990) Diabetes , vol.39 , pp. 1461-1466
    • MacDonald, M.J.1
  • 8
    • 33744505375 scopus 로고    scopus 로고
    • Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1
    • DOI 10.1016/j.cmet.2006.05.003, PII S1550413106001586
    • S.H. Um, D. D'Alessio, G. Thomas, Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1, Cell Metab. 3 (2006) 393-402. (Pubitemid 43811780)
    • (2006) Cell Metabolism , vol.3 , Issue.6 , pp. 393-402
    • Um, S.H.1    D'Alessio, D.2    Thomas, G.3
  • 9
    • 0035798097 scopus 로고    scopus 로고
    • Mammalian TOR: A homeostatic ATP sensor
    • DOI 10.1126/science.1063518
    • P.B. Dennis, A. Jaeschke, M. Saitoh, B. Fowler, S.C. Kozma, G. Thomas, Mammalian TOR: a homeostatic ATP sensor, Science 294 (2001) 1102-1105. (Pubitemid 33041865)
    • (2001) Science , vol.294 , Issue.5544 , pp. 1102-1105
    • Dennis, P.B.1    Jaeschke, A.2    Saitoh, M.3    Fowler, B.4    Kozma, S.C.5    Thomas, G.6
  • 10
    • 37149027613 scopus 로고    scopus 로고
    • Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism
    • DOI 10.1152/ajpendo.00134.2007
    • P. She, C. Van Horn, T. Reid, S.M. Hutson, R.N. Cooney, C.J. Lynch, Obesityrelated elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism, Am. J. Physiol. Endocrinol. Metab. 293 (2007) E1552-E1563. (Pubitemid 350255104)
    • (2007) American Journal of Physiology - Endocrinology and Metabolism , vol.293 , Issue.6
    • She, P.1    Van Horn, C.2    Reid, T.3    Hutson, S.M.4    Cooney, R.N.5    Lynch, C.J.6
  • 12
    • 0014669160 scopus 로고
    • Plasma amino acid levels and insulin secretion in obesity
    • P. Felig, E. Marliss, G.F. Cahill Jr., Plasma amino acid levels and insulin secretion in obesity, N. Engl. J. Med. 281 (1969) 811-816.
    • (1969) N. Engl. J. Med. , vol.281 , pp. 811-816
    • Felig, P.1    Marliss, E.2    Cahill Jr., G.F.3
  • 13
    • 20344391157 scopus 로고    scopus 로고
    • Markers associated with inborn errors of metabolism of branched-chain amino acids and their relevance to upper levels of intake in healthy people: An implication from clinical and molecular investigations on maple syrup urine disease
    • H. Mitsubuchi, M. Owada, F. Endo, Markers associated with inborn errors of metabolism of branched-chain amino acids and their relevance to upper levels of intake in healthy people: an implication from clinical and molecular investigations on maple syrup urine disease, J. Nutr. 135 (2005) 1565S-1570S. (Pubitemid 40791671)
    • (2005) Journal of Nutrition , vol.135 , Issue.6
    • Mitsubuchi, H.1    Owada, M.2    Endo, F.3
  • 14
    • 31544455515 scopus 로고    scopus 로고
    • Lessons from genetic disorders of branched-chain amino acid metabolism
    • D.T. Chuang, J.L. Chuang, R.M. Wynn, Lessons from genetic disorders of branched-chain amino acid metabolism, J. Nutr. 136 (2006) 243S-249S. (Pubitemid 43156517)
    • (2006) Journal of Nutrition , vol.136 , Issue.1
    • Chuang, D.T.1    Chuang, J.L.2    Wynn, R.M.3
  • 16
    • 9244261568 scopus 로고    scopus 로고
    • Evidence that the branched-chain -keto acids accumulating in maple syrup urine disease induce morphological alterations and death in cultured astrocytes from rat cerebral cortex
    • DOI 10.1002/glia.20072
    • C. Funchal, C. Gottfried, L.M. De Almeida, M. Wajner, R. Pessoa-Pureur, Evidence that the branched-chain a-keto acids accumulating in maple syrup urine disease induce morphological alterations and death in cultured astrocytes from rat cerebral cortex, Glia 48 (2004) 230-240. (Pubitemid 39549319)
    • (2004) GLIA , vol.48 , Issue.3 , pp. 230-240
    • Funchal, C.1    Gottfried, C.2    Vieira De Almeida, L.M.3    Wajner, M.4    Pessoa-Pureur, R.5
  • 20
    • 84873083880 scopus 로고    scopus 로고
    • A novel regulatory defect in the branched-chain a-ketoacid dehydrogenase complex due to a mutation in the ppm1k gene causes a mild variant phenotype of maple syrup urine disease
    • A. Oyarzabal, M. Martinez-Pardo, B. Merinero, R. Navarrete, L.R. Desviat, M. Ugarte, P. Rodriguez-Pombo, A novel regulatory defect in the branched-chain a-ketoacid dehydrogenase complex due to a mutation in the PPM1K gene causes a mild variant phenotype of maple syrup urine disease, Hum. Mutat. 34 (2013) 355-362.
    • (2013) Hum. Mutat. , vol.34 , pp. 355-362
    • Oyarzabal, A.M.1    Merinero, B.2    Navarrete, R.3    Desviat, L.R.4    Ugarte, M.P.5
  • 23
    • 79953755716 scopus 로고    scopus 로고
    • Catabolism of branched-chain amino acids in heart failure: Insights from genetic models
    • H. Sun, G. Lu, S. Ren, J. Chen, Y. Wang, Catabolism of branched-chain amino acids in heart failure: insights from genetic models, Pediatr. Cardiol. 32 (2011) 305-310.
    • (2011) Pediatr. Cardiol. , vol.32 , pp. 305-310
    • Sun, H.1    Lu, G.2    Ren, S.3    Chen, J.4    Wang, Y.5
  • 24
    • 23844540128 scopus 로고    scopus 로고
    • Morphological alterations and cell death provoked by the branched-chain -amino acids accumulating in maple syrup urine disease in astrocytes from rat cerebral cortex
    • DOI 10.1007/s10571-005-4938-6
    • C. Funchal, C. Gottfried, L.M. de Almeida, A.Q. dos Santos, M. Wajner, R. Pessoa-Pureur, Morphological alterations and cell death provoked by the branchedchain a-Amino acids accumulating in maple syrup urine disease in astrocytes from rat cerebral cortex, Cell. Mol. Neurobiol. 25 (2005) 851-867. (Pubitemid 41160103)
    • (2005) Cellular and Molecular Neurobiology , vol.25 , Issue.5 , pp. 851-867
    • Funchal, C.1    Gottfried, C.2    Vieira De Almeida, L.M.3    Dos Santos, A.Q.4    Wajner, M.5    Pessoa-Pureur, R.6
  • 25
    • 79955456000 scopus 로고    scopus 로고
    • Branched-chain amino acid metabolism in heart disease: An epiphenomenon or a real culprit?
    • Y. Huang, M. Zhou, H. Sun, Y. Wang, Branched-chain amino acid metabolism in heart disease: an epiphenomenon or a real culprit?, Cardiovasc Res. 90 (2011) 220-223.
    • (2011) Cardiovasc Res. , vol.90 , pp. 220-223
    • Huang, Y.1    Zhou, M.2    Sun, H.3    Wang, Y.4
  • 26
    • 84875164464 scopus 로고    scopus 로고
    • Whole body protein synthesis and breakdown
    • John Wiley, Hoboken, NJ
    • R.R. Wolfe, D.L. Chinkes, Whole body protein synthesis and breakdown, in: Isotope Tracers in Metabolic Research, John Wiley, Hoboken, NJ, 2005, pp. 299-323.
    • (2005) Isotope Tracers in Metabolic Research , pp. 299-323
    • Wolfe, R.R.1    Chinkes, D.L.2
  • 27
    • 0029115046 scopus 로고
    • Rapid quantitative determination of sialic acids in glycoproteins by high-performance liquid chromatography with a sensitive fluorescence detection
    • K.R. Anumula, Rapid quantitative determination of sialic acids in glycoproteins by high-performance liquid chromatography with a sensitive fluorescence detection, Anal. Biochem. 230 (1995) 24-30.
    • (1995) Anal. Biochem. , vol.230 , pp. 24-30
    • Anumula, K.R.1
  • 28
    • 0020289624 scopus 로고
    • High-performance liquid chromatographic determination of -keto acids in human urine and plasma
    • DOI 10.1016/0003-2697(82)90267-6
    • T. Hayashi, H. Tsuchiya, H. Todoriki, H. Naruse, High-performance liquid chromatographic determination of a-keto acids in human urine and plasma, Anal. Biochem. 122 (1982) 173-179. (Pubitemid 12014331)
    • (1982) Analytical Biochemistry , vol.122 , Issue.1 , pp. 173-179
    • Hayashi, T.1    Tsuchiya, H.2    Todoriki, H.3    Naruse, H.4
  • 29
    • 0020585756 scopus 로고
    • High-performance liquid chromatographic determination of -keto acids in plasma with fluorometric detection
    • T. Hayashi, H. Tsuchiya, H. Naruse, High-performance liquid chromatographic determination of a-keto acids in plasma with fluorometric detection, J. Chromatogr. 273 (1983) 245-252. (Pubitemid 13135563)
    • (1983) Journal of Chromatography , vol.273 , Issue.2 , pp. 245-252
    • Hayashi, T.1    Tsuchiya, H.2    Naruse, H.3
  • 30
    • 0021485786 scopus 로고
    • Fluorescent analysis of a-keto acids in serum and urine by high-performance liquid chromatography
    • K. Koike, M. Koike, Fluorescent analysis of a-keto acids in serum and urine by high-performance liquid chromatography, Anal. Biochem. 141 (1984) 481-487.
    • (1984) Anal. Biochem. , vol.141 , pp. 481-487
    • Koike, K.1    Koike, M.2
  • 31
    • 0022421659 scopus 로고
    • Determination of -keto acids in serum and urine by high-performance liquid chromatography with fluorescence detection
    • S. Hara, Y. Takemori, M. Yamaguchi, M. Nakamura, Y. Ohkura, Determination of a-keto acids in serum and urine by high-performance liquid chromatography with fluorescence detection, J. Chromatogr. 344 (1985) 33-39. (Pubitemid 16204242)
    • (1985) Journal of Chromatography - Biomedical Applications , vol.VOL. 344 , pp. 33-39
    • Hara, S.1    Takemori, Y.2    Yamaguchi, M.3    Nakamura, M.4
  • 32
    • 0034123725 scopus 로고    scopus 로고
    • Branched-chain keto-acids and pyruvate in blood: Measurement by hplc with fluorimetric detection and changes in older subjects
    • K. Pailla, F. Blonde-Cynober, C. Aussel, J.P. De Bandt, L. Cynober, Branchedchain keto-Acids and pyruvate in blood: measurement by HPLC with fluorimetric detection and changes in older subjects, Clin. Chem. 46 (2000) 848-853. (Pubitemid 30397450)
    • (2000) Clinical Chemistry , vol.46 , Issue.6 , pp. 848-853
    • Pailla, K.1    Blonde-Cynober, F.2    Aussel, C.3    De Bandt, J.-P.4    Cynober, L.5
  • 33
    • 67649235962 scopus 로고    scopus 로고
    • Determination of branched chain amino acids, methionine, phenylalanine, tyrosine, and a-keto acids in plasma and dried blood samples using hplc with fluorescence detection
    • R. Kand'ar, P. Zakova, J. Jirosova, M. Sladka, Determination of branched chain amino acids, methionine, phenylalanine, tyrosine, and a-keto acids in plasma and dried blood samples using HPLC with fluorescence detection, Clin. Chem. Lab. Med. 47 (2009) 565-572.
    • (2009) Clin. Chem. Lab. Med. , vol.47 , pp. 565-572
    • Kand'ar, R.1    Zakova, P.2    Jirosova, J.3    Sladka, M.4
  • 34
    • 0022801127 scopus 로고
    • Quantitation of branched-chain a-keto acids as their n-methylquinoxalone derivatives: Comparison of o-And n-Alkylation versus -silylation
    • A.A. Fernandes, S.C. Kalhan, F.G. Njoroge, G.S. Matousek, Quantitation of branched-chain a-keto acids as their N-methylquinoxalone derivatives: comparison of O-And N-Alkylation versus -silylation, Biomed. Environ. Mass Spectrom. 13 (1986) 569-581.
    • (1986) Biomed. Environ. Mass Spectrom. , vol.13 , pp. 569-581
    • Fernandes, A.A.1    Kalhan, S.C.2    Njoroge, F.G.3    Matousek, G.S.4
  • 35
    • 0018404125 scopus 로고
    • Gas-liquid chromatography of a-keto acids: Quantification of the branched-chain a-keto acids from physiological sources
    • T.C. Cree, S.M. Hutson, A.E. Harper, Gas-liquid chromatography of a-keto acids: quantification of the branched-chain a-keto acids from physiological sources, Anal. Biochem. 92 (1979) 159-163.
    • (1979) Anal. Biochem. , vol.92 , pp. 159-163
    • Cree, T.C.1    Hutson, S.M.2    Harper, A.E.3
  • 36
    • 0024215484 scopus 로고
    • Measurement of plasma and tissue levels of brached-chain -keto acids by gas-liquid chromatography
    • DOI 10.1016/S0076-6879(88)66009-5
    • P.L. Crowell, R.H. Miller, A.E. Harper, Measurement of plasma and tissue levels of branched-chain a-keto acids by gas-liquid chromatography, Methods Enzymol. 166 (1988) 39-46. (Pubitemid 19048577)
    • (1988) Methods in Enzymology , vol.166 , pp. 39-46
    • Crowell, P.L.1    Miller, R.H.2    Harper, A.E.3
  • 37
    • 0019365577 scopus 로고
    • Blood and tissue branched-chain amino and -keto acid concentrations: Effect of diet, starvation, and disease
    • S.M. Hutson, A.E. Harper, Blood and tissue branched-chain amino and a-keto acid concentrations: effect of diet, starvation, and disease, Am. J. Clin. Nutr. 34 (1981) 173-183. (Pubitemid 11186307)
    • (1981) American Journal of Clinical Nutrition , vol.34 , Issue.2 , pp. 173-183
    • Hutson, S.M.1    Harper, A.E.2
  • 38
    • 0023219799 scopus 로고
    • Measurement of branched-chain ketoacids in plasma by high-performance liquid chromatography
    • M. Walser, L.M. Swain, V. Alexander, Measurement of branched-chain ketoacids in plasma by high-performance liquid chromatography, Anal. Biochem. 164 (1987) 287-291. (Pubitemid 17123606)
    • (1987) Analytical Biochemistry , vol.164 , Issue.2 , pp. 287-291
    • Walser, M.1    Swain, L.M.2    Alexander, V.3
  • 39
    • 0037807642 scopus 로고
    • Reversed-phase high-performance liquidchromatographic analysis of a-keto acid quinoxalinol derivatives: Optimization of technique and application to natural samples
    • D.J. Kieber,K.Mopper, Reversed-phase high-performance liquidchromatographic analysis of a-keto acid quinoxalinol derivatives: optimization of technique and application to natural samples, J. Chromatogr. A 281 (1983) 135-149.
    • (1983) J. Chromatogr. A , vol.281 , pp. 135-149
    • Kieber, D.J.1    Mopper, K.2
  • 41
    • 33646195697 scopus 로고    scopus 로고
    • Production and characterization of murine models of classic and intermediate maple syrup urine disease
    • G.E. Homanics, K. Skvorak, C. Ferguson, S. Watkins, H.S. Paul, Production and characterization of murine models of classic and intermediate maple syrup urine disease, BMC Med. Genet. 7 (2006) 33.
    • (2006) BMC Med. Genet. , vol.7 , pp. 33
    • Homanics, G.E.1    Skvorak, K.2    Ferguson, C.3    Watkins, S.4    Paul, H.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.