Cross-talk between branched-chain amino acids and hepatic mitochondria is compromised in nonalcoholic fatty liver disease

American Journal of Physiology - Endocrinology and Metabolism

Volumn 309, Issue 4, 2015, Pages E311-E319

  Sunny, Nishanth E ^a   Kalavalapalli, Srilaxmi ^a   Bril, Fernando ^a   Garrett, Timothy J ^b   Nautiyal, Manisha ^a   Mathew, Justin T ^a   Williams, Caroline M ^f   Cusi, Kenneth ^a,c,d,e  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d Mays Cancer Center at UT Health San Antonio   (United States)

^e SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Branched chain amino acids; Insulin resistance; Mitochondrial metabolism; Nonalcoholic fatty liver disease

Indexed keywords

ACYLCARNITINE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BRANCHED CHAIN AMINO ACID; CARBON; FATTY ACID; GLUCOSE; HEMOGLOBIN A1C; INSULIN; ISOLEUCINE; KETONE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; TRICARBOXYLIC ACID; VALINE;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY FAT; BODY MASS; CATABOLISM; CITRIC ACID CYCLE; CONTROLLED STUDY; DIET RESTRICTION; FATTY ACID BLOOD LEVEL; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE CLAMP TECHNIQUE; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIVER MITOCHONDRION; MAJOR CLINICAL STUDY; MALE; METABOLIC FLUX ANALYSIS; METABOLITE; METABOLOMICS; MITOCHONDRIAL RESPIRATION; MOLECULAR INTERACTION; MOUSE; MOUSE MODEL; NONALCOHOLIC FATTY LIVER; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXIDATION; PRIORITY JOURNAL; PROVOCATION TEST; UPREGULATION; ANIMAL; C57BL MOUSE; CLINICAL TRIAL; DRUG EFFECTS; LIPID METABOLISM; LIVER; METABOLISM; MIDDLE AGED; PATHOLOGY; SIGNAL TRANSDUCTION;

AMINO ACIDS, BRANCHED-CHAIN; ANIMALS; CITRIC ACID CYCLE; FEMALE; GLUCOSE CLAMP TECHNIQUE; HUMANS; INSULIN; INSULIN RESISTANCE; LIPID METABOLISM; LIVER; MALE; MICE; MICE, INBRED C57BL; MIDDLE AGED; MITOCHONDRIA, LIVER; NON-ALCOHOLIC FATTY LIVER DISEASE; RECEPTOR CROSS-TALK;

EID: 84939432312     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00161.2015     Document Type: Article

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