Functional and structural divergence in human TRPV1 channel subunits by oxidative cysteine modification

Journal of Biological Chemistry

Volumn 291, Issue 8, 2016, Pages 4197-4210

  Ogawa, Nozomi ^a   Kurokawa, Tatsuki ^a   Fujiwara, Kenji ^a   Polat, Onur Kerem ^a   Badr, Heba ^a   Takahashi, Nobuaki ^b   Mori, Yasuo ^a  

^a KYOTO UNIVERSITY   (Japan)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; COVALENT BONDS; ELECTROPHYSIOLOGY; MASS SPECTROMETRY; NEURONS; PROTEINS; SPECTROMETRY; SULFUR COMPOUNDS;

CHANNEL STABILITY; DISULFIDE BONDS; INFLAMMATORY MEDIATORS; MASS SPECTROMETRIC ANALYSIS; OXIDATIVE STATUS; STRUCTURAL DIVERGENCE; TETRAMERIC COMPLEX; TRANSIENT RECEPTOR POTENTIAL VANILLOID;

OXIDATION;

CYSTEINE; VANILLOID RECEPTOR 1; HYDROGEN PEROXIDE; TRPV1 PROTEIN, HUMAN; VANILLOID RECEPTOR;

AMINO ACID METABOLISM; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DIMERIZATION; DISULFIDE BOND; ELECTROPHYSIOLOGY; EMBRYO; HALF LIFE TIME; HUMAN; HUMAN CELL; MASS SPECTROMETRY; OXIDATION REDUCTION STATE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN STABILITY; STRUCTURE ACTIVITY RELATION; AMINO ACID SUBSTITUTION; ANIMAL; CHEMISTRY; GENETICS; HEK293 CELL LINE; METABOLISM; MISSENSE MUTATION; OXIDATION REDUCTION REACTION; PROTEIN MULTIMERIZATION; PROTEIN PROCESSING; RAT;

AMINO ACID SUBSTITUTION; ANIMALS; CYSTEINE; HEK293 CELLS; HUMANS; HYDROGEN PEROXIDE; MUTATION, MISSENSE; OXIDATION-REDUCTION; PROTEIN MULTIMERIZATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; TRPV CATION CHANNELS;

EID: 84964561173     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.700278     Document Type: Article

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