Role of TRPA1 and TRPV1 in the ROS-dependent sensory irritation of superior laryngeal capsaicin-sensitive afferents by cigarette smoke in anesthetized rats

Pulmonary Pharmacology and Therapeutics

Volumn 26, Issue 3, 2013, Pages 364-372

  Liu, Bi Yu ^a   Tsai, Tung Lung ^b   Ho, Ching Yin ^a,b   Lu, Shing Hwa ^c   Lai, Ching Jung ^d   Kou, Yu Ru ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^c TAIPEI CITY HOSPITAL   (Taiwan)

^d TZU CHI UNIVERSITY   (Taiwan)

Author keywords

Cigarette smoke; Laryngeal capsaicin sensitive afferents; Laryngeal sensory irritation; Reactive oxygen species; TRPA1; TRPV1

Indexed keywords

ACETYLCYSTEINE; BAPTA AM; CALCIUM CHELATING AGENT; CALCIUM ION; CAPSAICIN; CAPSAZEPINE; CIGARETTE SMOKE; EGTAZIC ACID; INDOMETACIN; N (4 ISOPROPYLPHENYL) 2 (1,2,3,6 TETRAHYDRO 1,3 DIMETHYL 2,6 DIOXO 7H PURIN 7 YL)ACETAMIDE; REACTIVE OXYGEN METABOLITE; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APNEA; ARTICLE; BREATHING PATTERN; BREATHING REFLEX; CONTROLLED STUDY; HEART RATE; LARYNX DISORDER; MALE; MEAN ARTERIAL PRESSURE; MECHANICAL STIMULATION; NERVE CONDUCTION; NONHUMAN; PERIPHERAL NEUROPATHY; PNEUMOTACHYGRAPHY; PREMEDICATION; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; RESPIRATORY AIRFLOW; SMOKING; SUPERIOR LARYNGEAL NERVE; SUPERIOR LARYNGEAL NERVE IRRITATION; TIDAL VOLUME;

ACETANILIDES; ACETYLCYSTEINE; ANIMALS; ANTIOXIDANTS; APNEA; CALCIUM CHANNELS; CAPSAICIN; CHELATING AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; EGTAZIC ACID; INDOMETHACIN; LARYNGEAL NERVES; LARYNX; NEURONS, AFFERENT; PURINES; RATS; REACTIVE OXYGEN SPECIES; SMOKING; TRPC CATION CHANNELS; TRPV CATION CHANNELS;

EID: 84875920432     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2013.01.010     Document Type: Article

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