Thiol-blocking electrophiles interfere with labeling and detection of protein sulfenic acids

FEBS Journal

Volumn 280, Issue 23, 2013, Pages 6150-6161

  Reisz, Julie A ^a   Bechtold, Erika ^b,c   King, S Bruce ^b   Poole, Leslie B ^a   Furdui, Cristina M ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b WAKE FOREST UNIVERSITY   (United States)

^c TUFTS UNIVERSITY   (United States)

Author keywords

dimedone; mass spectrometry; protein sulfenic acid; S nitrosation; thiol blocking

Indexed keywords

5,5 DIMETHYL 1,3 CYCLOHEXANEDIONE; ASCORBIC ACID; CYSTEINE; DITHIOTHREITOL; DNA; ELECTROPHILE; IODOACETAMIDE; N ETHYLMALEIMIDE; REACTIVE OXYGEN METABOLITE; SULFENIC ACID DERIVATIVE; THIOMESYLIC ACID METHYL ESTER; TRIS(2 CARBOXYETHYL)PHOSPHINE;

ALKYLATION; ARTICLE; CHEMICAL LABELING; CHEMICAL REACTION; CROSS REACTION; KINETICS; LIPID OXIDATION; NUCLEOPHILICITY; PATHOLOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PROCESSING;

DIMEDONE; MASS SPECTROMETRY; PROTEIN SULFENIC ACID; S-NITROSATION; THIOL BLOCKING;

ASCORBIC ACID; CYCLOHEXANONES; CYSTEINE; DITHIOTHREITOL; ETHYLMALEIMIDE; IODOACETAMIDE; METHYL METHANESULFONATE; OXIDATION-REDUCTION; PROTEINS; REACTIVE OXYGEN SPECIES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SULFENIC ACIDS; SULFHYDRYL COMPOUNDS;

EID: 84888301385     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12535     Document Type: Article

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