Targeting the Transient Receptor Potential Vanilloid Type 1 (TRPV1) assembly domain attenuates inflammation-induced hypersensitivity

Journal of Biological Chemistry

Volumn 289, Issue 24, 2014, Pages 16675-16687

  Flynn, Robyn ^a   Chapman, Kevin ^a   Iftinca, Mircea ^a   Aboushousha, Reem ^a   Varela, Diego ^b   Altier, Christophe ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF CHILE   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTROPHYSIOLOGY; NEURONS;

BIOCHEMICAL ASSAY; BIOLUMINESCENCE RESONANCE ENERGY TRANSFER; ESSENTIAL ELEMENTS; FUNCTIONAL CHANNELS; NON-SELECTIVE CATION CHANNELS; SUBUNIT ASSOCIATIONS; TRANSIENT RECEPTOR POTENTIAL CHANNELS; TRANSIENT RECEPTOR POTENTIAL VANILLOID;

CELL MEMBRANES;

VANILLOID RECEPTOR 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOLUMINESCENCE RESONANCE ENERGY TRANSFER; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ELECTROPHYSIOLOGY; HYPERALGESIA; HYPERSENSITIVITY; IMMUNOCYTOCHEMISTRY; IMMUNOPRECIPITATION; INFLAMMATION; KIDNEY CELL; MALE; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL; WESTERN BLOTTING;

BIOLUMINESCENCE RESONANCE ENERGY TRANSFER (BRET); BIOMOLECULAR FLUORESCENCE COMPLEMENTATION; PAIN; PROTEIN ASSEMBLY; SITE-DIRECTED MUTAGENESIS; TRAFFICKING; TRANSIENT RECEPTOR POTENTIAL CHANNELS (TRP CHANNELS);

AMINO ACID MOTIFS; ANIMALS; ARTHRITIS, EXPERIMENTAL; BINDING SITES; GENE DELETION; HEK293 CELLS; HUMANS; HYPERALGESIA; INFLAMMATION; MALE; MICE; MICE, INBRED C57BL; PROTEIN MULTIMERIZATION; PROTEIN SUBUNITS; PROTEIN TRANSPORT; RATS; TRPV CATION CHANNELS;

EID: 84902438344     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.558668     Document Type: Article

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