-
1
-
-
84875490185
-
Cancer genome landscapes
-
Vogelstein, B., Papadopoulos, N., Velculescu, V. E., Zhou, S., Diaz, L. A. and Kinzler, K. W. (2013) Cancer Genome Landscapes. Science, 339, 1546-1558.
-
(2013)
Science
, vol.339
, pp. 1546-1558
-
-
Vogelstein, B.1
Papadopoulos, N.2
Velculescu, V.E.3
Zhou, S.4
Diaz, L.A.5
Kinzler, K.W.6
-
2
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan, D. and Weinberg, R. A. Hallmarks of Cancer: The Next Generation. Cell, 144, 646-674.
-
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
3
-
-
0345357773
-
Gene silencing in cancer in association with promoter hypermethylation
-
Herman, J. G. and Baylin, S. B. (2003) Gene Silencing in Cancer in Association with Promoter Hypermethylation. N. Engl. J. Med., 349, 2042-2054.
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 2042-2054
-
-
Herman, J.G.1
Baylin, S.B.2
-
4
-
-
0037455915
-
Epigenetic gene silencing in cancer initiation and progression
-
Nephew, K. P. and Huang, T. H.-M. (2003) Epigenetic gene silencing in cancer initiation and progression. Cancer Letters, 190, 125-133.
-
(2003)
Cancer Letters
, vol.190
, pp. 125-133
-
-
Nephew, K.P.1
Huang, T.H.-M.2
-
5
-
-
85027954125
-
DNA methylation profiling in the clinic: Applications and challenges
-
Heyn, H. and Esteller, M. (2012) DNA methylation profiling in the clinic: applications and challenges. Nat. Rev. Genet., 13, 679-692.
-
(2012)
Nat. Rev. Genet.
, vol.13
, pp. 679-692
-
-
Heyn, H.1
Esteller, M.2
-
6
-
-
84868206265
-
Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues
-
Landan, G., Cohen, N. M., Mukamel, Z., Bar, A., Molchadsky, A., Brosh, R., Horn-Saban, S., Zalcenstein, D. A., Goldfinger, N., Zundelevich, A. et al. (2012) Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues. Nat. Genet., 44, 1207-1214.
-
(2012)
Nat. Genet.
, vol.44
, pp. 1207-1214
-
-
Landan, G.1
Cohen, N.M.2
Mukamel, Z.3
Bar, A.4
Molchadsky, A.5
Brosh, R.6
Horn-Saban, S.7
Zalcenstein, D.A.8
Goldfinger, N.9
Zundelevich, A.10
-
7
-
-
29244469466
-
The epigenetic progenitor origin of human cancer
-
Feinberg, A. P., Ohlsson, R. and Henikoff, S. (2006) The epigenetic progenitor origin of human cancer. Nat. Rev. Genet., 7, 21-33.
-
(2006)
Nat. Rev. Genet.
, vol.7
, pp. 21-33
-
-
Feinberg, A.P.1
Ohlsson, R.2
Henikoff, S.3
-
8
-
-
84901853867
-
Cancer epigenetics: Tumor heterogeneity, plasticity of stem-like states, and drug resistance
-
Easwaran, H., Tsai, H.-C. and Baylin, S. B. Cancer Epigenetics: Tumor Heterogeneity, Plasticity of Stem-like States, and Drug Resistance. Mol. Cell, 54, 716-727.
-
Mol. Cell
, vol.54
, pp. 716-727
-
-
Easwaran, H.1
Tsai, H.-C.2
Baylin, S.B.3
-
9
-
-
84908251818
-
Poised epigenetic states and acquired drug resistance in cancer
-
Brown, R., Curry, E., Magnani, L., Wilhelm-Benartzi, C. S. and Borley, J. (2014) Poised epigenetic states and acquired drug resistance in cancer. Nat. Rev. Cancer., 14, 747-753.
-
(2014)
Nat. Rev. Cancer.
, vol.14
, pp. 747-753
-
-
Brown, R.1
Curry, E.2
Magnani, L.3
Wilhelm-Benartzi, C.S.4
Borley, J.5
-
10
-
-
77950809059
-
A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations
-
Sharma, S. V., Lee, D. Y., Li, B., Quinlan, M. P., Takahashi, F., Maheswaran, S., McDermott, U., Azizian, N., Zou, L., Fischbach, M. A. et al. (2010) A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations. Cell, 141, 69-80.
-
(2010)
Cell
, vol.141
, pp. 69-80
-
-
Sharma, S.V.1
Lee, D.Y.2
Li, B.3
Quinlan, M.P.4
Takahashi, F.5
Maheswaran, S.6
McDermott, U.7
Azizian, N.8
Zou, L.9
Fischbach, M.A.10
-
11
-
-
84884377472
-
Tumour heterogeneity and cancer cell plasticity
-
Meacham, C. E. and Morrison, S. J. (2013) Tumour heterogeneity and cancer cell plasticity. Nature, 501, 328-337.
-
(2013)
Nature
, vol.501
, pp. 328-337
-
-
Meacham, C.E.1
Morrison, S.J.2
-
12
-
-
84884407337
-
Tumour heterogeneity in the clinic
-
Bedard, P. L., Hansen, A. R., Ratain, M. J. and Siu, L. L. (2013) Tumour heterogeneity in the clinic. Nature, 501, 355-364.
-
(2013)
Nature
, vol.501
, pp. 355-364
-
-
Bedard, P.L.1
Hansen, A.R.2
Ratain, M.J.3
Siu, L.L.4
-
13
-
-
84859113048
-
Genetic heterogeneity and cancer drug resistance
-
Turner, N. C. and Reis-Filho, J. S. (2012) Genetic heterogeneity and cancer drug resistance. Lancet Oncol., 13, e178-e185.
-
(2012)
Lancet Oncol.
, vol.13
, pp. e178-e185
-
-
Turner, N.C.1
Reis-Filho, J.S.2
-
14
-
-
84919469035
-
Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemia
-
Landau, D. A., Clement, K., Ziller, M. J., Boyle, P., Fan, J., Gu, H., Stevenson, K., Sougnez, C., Wang, L., Li, S. et al. Locally Disordered Methylation Forms the Basis of Intratumor Methylome Variation in Chronic Lymphocytic Leukemia. Cancer Cell, 26, 813-825.
-
Cancer Cell
, vol.26
, pp. 813-825
-
-
Landau, D.A.1
Clement, K.2
Ziller, M.J.3
Boyle, P.4
Fan, J.5
Gu, H.6
Stevenson, K.7
Sougnez, C.8
Wang, L.9
Li, S.10
-
15
-
-
84895783051
-
Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia
-
Oakes, C. C., Claus, R., Gu, L., Assenov, Y., Hüllein, J., Zucknick, M., Bieg, M., Brocks, D., Bogatyrova, O., Schmidt, C. R. et al. (2014) Evolution of DNA Methylation Is Linked to Genetic Aberrations in Chronic Lymphocytic Leukemia. Cancer Discov., 4, 348-361.
-
(2014)
Cancer Discov.
, vol.4
, pp. 348-361
-
-
Oakes, C.C.1
Claus, R.2
Gu, L.3
Assenov, Y.4
Hüllein, J.5
Zucknick, M.6
Bieg, M.7
Brocks, D.8
Bogatyrova, O.9
Schmidt, C.R.10
-
16
-
-
79957458567
-
Cell-free nucleic acids as biomarkers in cancer patients
-
Schwarzenbach, H., Hoon, D. S. B. and Pantel, K. (2011) Cell-free nucleic acids as biomarkers in cancer patients. Nat. Rev. Cancer, 11, 426-437.
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 426-437
-
-
Schwarzenbach, H.1
Hoon, D.S.B.2
Pantel, K.3
-
17
-
-
84907207898
-
Dynamic and static maintenance of epigenetic memory in pluripotent and somatic cells
-
Shipony, Z., Mukamel, Z., Cohen, N. M., Landan, G., Chomsky, E., Zeliger, S. R., Fried, Y. C., Ainbinder, E., Friedman, N. and Tanay, A. (2014) Dynamic and static maintenance of epigenetic memory in pluripotent and somatic cells. Nature, 513, 115-119.
-
(2014)
Nature
, vol.513
, pp. 115-119
-
-
Shipony, Z.1
Mukamel, Z.2
Cohen, N.M.3
Landan, G.4
Chomsky, E.5
Zeliger, S.R.6
Fried, Y.C.7
Ainbinder, E.8
Friedman, N.9
Tanay, A.10
-
18
-
-
84874025843
-
Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples
-
Cibulskis, K., Lawrence, M. S., Carter, S. L., Sivachenko, A., Jaffe, D., Sougnez, C., Gabriel, S., Meyerson, M., Lander, E. S. and Getz, G. (2013) Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples. Nat. Biotech., 31, 213-219.
-
(2013)
Nat. Biotech.
, vol.31
, pp. 213-219
-
-
Cibulskis, K.1
Lawrence, M.S.2
Carter, S.L.3
Sivachenko, A.4
Jaffe, D.5
Sougnez, C.6
Gabriel, S.7
Meyerson, M.8
Lander, E.S.9
Getz, G.10
-
19
-
-
84898542288
-
Liquid biopsies: Genotyping circulating tumor DNA
-
Diaz, L. A. and Bardelli, A. (2014) Liquid Biopsies: Genotyping Circulating Tumor DNA. J. Clin. Oncol., 32, 579-586.
-
(2014)
J. Clin. Oncol.
, vol.32
, pp. 579-586
-
-
Diaz, L.A.1
Bardelli, A.2
-
20
-
-
85015462482
-
Current challenges for detection of circulating tumor cells and cell-free circulating nucleic acids, and their characterization in non-small cell lung carcinoma patients. What is the best blood substrate for personalized medicine?
-
Ilie, M., Hofman, V., Long, E., Bordone, O., Selva, E., Washetine, K., Marquette, C. H. and Hofman, P. (2014) Current challenges for detection of circulating tumor cells and cell-free circulating nucleic acids, and their characterization in non-small cell lung carcinoma patients. What is the best blood substrate for personalized medicine? Ann. Transl. Med., 2, 107.
-
(2014)
Ann. Transl. Med.
, vol.2
, pp. 107
-
-
Ilie, M.1
Hofman, V.2
Long, E.3
Bordone, O.4
Selva, E.5
Washetine, K.6
Marquette, C.H.7
Hofman, P.8
-
21
-
-
0036241916
-
Molecular mechanisms of gene silencing mediated by DNA methylation
-
Curradi, M., Izzo, A., Badaracco, G. and Landsberger, N. (2002) Molecular Mechanisms of Gene Silencing Mediated by DNA Methylation. Mol. Cell. Biol., 22, 3157-3173.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 3157-3173
-
-
Curradi, M.1
Izzo, A.2
Badaracco, G.3
Landsberger, N.4
-
22
-
-
0029843950
-
Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands
-
Herman, J. G., Graff, J. R., Mÿohänen, S., Nelkin, B. D. and Baylin, S. B. (1996) Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc. Nat. Acad. Sci., 93, 9821-9826.
-
(1996)
Proc. Nat. Acad. Sci.
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Mÿohänen, S.3
Nelkin, B.D.4
Baylin, S.B.5
-
23
-
-
0033566692
-
Quantitative analysis of aberrant p16 methylation using real-time quantitativemethylation-specific polymerase chain reaction
-
Lo, Y. M. D., Wong, I. H. N., Zhang, J., Tein, M. S. C., Ng, M. H. L. and Hjelm, N. M. (1999) Quantitative Analysis of Aberrant p16 Methylation Using Real-Time QuantitativeMethylation-specific Polymerase Chain Reaction. Cancer Res., 59, 3899-3903.
-
(1999)
Cancer Res.
, vol.59
, pp. 3899-3903
-
-
Lo, Y.M.D.1
Wong, I.H.N.2
Zhang, J.3
Tein, M.S.C.4
Ng, M.H.L.5
Hjelm, N.M.6
-
24
-
-
0034654669
-
MethyLight: A high-throughput assay to measure DNA methylation
-
Eads, C. A., Danenberg, K. D., Kawakami, K., Saltz, L. B., Blake, C., Shibata, D., Danenberg, P. V. and Laird, P. W. (2000) MethyLight: a high-throughput assay to measure DNA methylation. Nucleic Acids Res., 28, e32.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. e32
-
-
Eads, C.A.1
Danenberg, K.D.2
Kawakami, K.3
Saltz, L.B.4
Blake, C.5
Shibata, D.6
Danenberg, P.V.7
Laird, P.W.8
-
25
-
-
33644649616
-
High-throughput DNA methylation profiling using universal bead arrays
-
Bibikova, M., Lin, Z., Zhou, L., Chudin, E., Garcia, E. W., Wu, B., Doucet, D., Thomas, N. J., Wang, Y., Vollmer, E. et al. (2006) High-throughput DNA methylation profiling using universal bead arrays. Genome Res., 16, 383-393.
-
(2006)
Genome Res.
, vol.16
, pp. 383-393
-
-
Bibikova, M.1
Lin, Z.2
Zhou, L.3
Chudin, E.4
Garcia, E.W.5
Wu, B.6
Doucet, D.7
Thomas, N.J.8
Wang, Y.9
Vollmer, E.10
-
26
-
-
34548734299
-
Ultradeep bisulfite sequencing analysis of DNA methylation patterns in multiple gene promoters by 454 sequencing
-
Taylor, K. H., Kramer, R. S., Davis, J. W., Guo, J., Duff, D. J., Xu, D., Caldwell, C. W. and Shi, H. (2007) Ultradeep Bisulfite Sequencing Analysis of DNA Methylation Patterns in Multiple Gene Promoters by 454 Sequencing. Cancer Res., 67, 8511-8518.
-
(2007)
Cancer Res.
, vol.67
, pp. 8511-8518
-
-
Taylor, K.H.1
Kramer, R.S.2
Davis, J.W.3
Guo, J.4
Duff, D.J.5
Xu, D.6
Caldwell, C.W.7
Shi, H.8
-
27
-
-
27144500218
-
Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis
-
Meissner, A., Gnirke, A., Bell, G. W., Ramsahoye, B., Lander, E. S. and Jaenisch, R. (2005) Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis. Nucleic Acids Res., 33, 5868-5877.
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 5868-5877
-
-
Meissner, A.1
Gnirke, A.2
Bell, G.W.3
Ramsahoye, B.4
Lander, E.S.5
Jaenisch, R.6
-
28
-
-
77955450160
-
The implications of heterogeneous DNA methylation for the accurate quantification of methylation
-
Mikeska, T., Candiloro, I. L. M. and Dobrovic, A. (2010) The implications of heterogeneous DNA methylation for the accurate quantification of methylation. Epigenomics, 2, 561-573.
-
(2010)
Epigenomics
, vol.2
, pp. 561-573
-
-
Mikeska, T.1
Candiloro, I.L.M.2
Dobrovic, A.3
-
29
-
-
77249137168
-
Principles and challenges of genome-wide DNA methylation analysis
-
Laird, P. W. (2010) Principles and challenges of genome-wide DNA methylation analysis. Nat. Rev. Genet., 11, 191-203.
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 191-203
-
-
Laird, P.W.1
-
30
-
-
84903218109
-
An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage
-
Newman, A. M., Bratman, S. V., To, J., Wynne, J. F., Eclov, N. C. W., Modlin, L. A., Liu, C. L., Neal, J. W., Wakelee, H. A., Merritt, R. E. et al. (2014) An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage. Nat. Med., 20, 552-558.
-
(2014)
Nat. Med.
, vol.20
, pp. 552-558
-
-
Newman, A.M.1
Bratman, S.V.2
To, J.3
Wynne, J.F.4
Eclov, N.C.W.5
Modlin, L.A.6
Liu, C.L.7
Neal, J.W.8
Wakelee, H.A.9
Merritt, R.E.10
-
31
-
-
69049103181
-
Intra-tumor heterogeneity of MLH1 promoter methylation revealed by deep single molecule bisulfite sequencing
-
Varley, K. E., Mutch, D. G., Edmonston, T. B., Goodfellow, P. J. and Mitra, R. D. (2009) Intra-tumor heterogeneity of MLH1 promoter methylation revealed by deep single molecule bisulfite sequencing. Nucleic Acids Res., 37, 4603-4612.
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 4603-4612
-
-
Varley, K.E.1
Mutch, D.G.2
Edmonston, T.B.3
Goodfellow, P.J.4
Mitra, R.D.5
-
32
-
-
84916638952
-
Heterogeneous DNA methylation contributes to tumorigenesis through inducing the loss of coexpression connectivity in colorectal cancer
-
Wang, Q., Jia, P., Cheng, F. and Zhao, Z. (2015) Heterogeneous DNA methylation contributes to tumorigenesis through inducing the loss of coexpression connectivity in colorectal cancer. Genes Chromosomes Cancer, 54, 110-121.
-
(2015)
Genes Chromosomes Cancer
, vol.54
, pp. 110-121
-
-
Wang, Q.1
Jia, P.2
Cheng, F.3
Zhao, Z.4
-
33
-
-
0034723255
-
Methylation patterns of the E-cadherin 5' CpG island are unstable and reflect the dynamic, heterogeneous loss of E-cadherin expression during metastatic progression
-
Graff, J. R., Gabrielson, E., Fujii, H., Baylin, S. B. and Herman, J. G. (2000) Methylation patterns of the E-cadherin 5' CpG island are unstable and reflect the dynamic, heterogeneous loss of E-cadherin expression during metastatic progression. J. Biol. Chem., 275, 2727-2732.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2727-2732
-
-
Graff, J.R.1
Gabrielson, E.2
Fujii, H.3
Baylin, S.B.4
Herman, J.G.5
-
34
-
-
84901840587
-
Clonal intratumor heterogeneity of promoter hypermethylation in breast cancer by MS-MLPA
-
Moelans, C. B., De Groot, J. S., Pan, X., Van Der Wall, E. and Van Diest, P. J. (2014) Clonal intratumor heterogeneity of promoter hypermethylation in breast cancer by MS-MLPA. Mod. Pathol., 27, 869-874.
-
(2014)
Mod. Pathol.
, vol.27
, pp. 869-874
-
-
Moelans, C.B.1
De Groot, J.S.2
Pan, X.3
Van Der Wall, E.4
Van Diest, P.J.5
-
35
-
-
84893671693
-
Multiplex mapping of chromatin accessibility and DNA methylation within targeted single molecules identifies epigenetic heterogeneity in neural stem cells and glioblastoma
-
Nabilsi, N. H., Deleyrolle, L. P., Darst, R. P., Riva, A., Reynolds, B. A. and Kladde, M. P. (2014) Multiplex mapping of chromatin accessibility and DNA methylation within targeted single molecules identifies epigenetic heterogeneity in neural stem cells and glioblastoma. Genome Res., 24, 329-339.
-
(2014)
Genome Res.
, vol.24
, pp. 329-339
-
-
Nabilsi, N.H.1
Deleyrolle, L.P.2
Darst, R.P.3
Riva, A.4
Reynolds, B.A.5
Kladde, M.P.6
-
36
-
-
63349097282
-
Methylation-sensitive high-resolution melting
-
Wojdacz, T. K., Dobrovic, A. and Hansen, L. L. (2008) Methylation-sensitive high-resolution melting. Nat. Protoc., 3, 1903-1908.
-
(2008)
Nat. Protoc.
, vol.3
, pp. 1903-1908
-
-
Wojdacz, T.K.1
Dobrovic, A.2
Hansen, L.L.3
-
37
-
-
19744383664
-
BiSearch: Primer-design and search tool for PCR on bisulfite-treated genomes
-
Tusńady, G. E., Simon, I., Váradi, A. and Aŕanyi, T. (2005) BiSearch: primer-design and search tool for PCR on bisulfite-treated genomes. Nucleic Acids Res., 33, e9.
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. e9
-
-
Tusńady, G.E.1
Simon, I.2
Váradi, A.3
Aŕanyi, T.4
-
38
-
-
79953313021
-
Umelt: Prediction of high-resolution melting curves and dynamic melting profiles of PCR products in a rich web application
-
Dwight, Z., Palais, R. and Wittwer, C. T. (2011) uMELT: prediction of high-resolution melting curves and dynamic melting profiles of PCR products in a rich web application. Bioinformatics, 27, 1019-1020.
-
(2011)
Bioinformatics
, vol.27
, pp. 1019-1020
-
-
Dwight, Z.1
Palais, R.2
Wittwer, C.T.3
-
39
-
-
18344390653
-
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
-
Rhee, I., Bachman, K. E., Park, B. H., Jair, K.-W., Yen, R.-W. C., Schuebel, K. E., Cui, H., Feinberg, A. P., Lengauer, C., Kinzler, K. W. et al. (2002) DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature, 416, 552-556.
-
(2002)
Nature
, vol.416
, pp. 552-556
-
-
Rhee, I.1
Bachman, K.E.2
Park, B.H.3
Jair, K.-W.4
Yen, R.-W.C.5
Schuebel, K.E.6
Cui, H.7
Feinberg, A.P.8
Lengauer, C.9
Kinzler, K.W.10
-
40
-
-
84883029814
-
Extraction and processing of circulating DNA from large sample volumes using methylation on beads for the detection of rare epigenetic events
-
Keeley, B., Stark, A., Pisanic II, T. R., Kwak, R., Zhang, Y., Wrangle, J., Baylin, S., Herman, J., Ahuja, N., Brock, M. V. et al. (2013) Extraction and processing of circulating DNA from large sample volumes using methylation on beads for the detection of rare epigenetic events. Clin. Chim. Acta, 425, 169-175.
-
(2013)
Clin. Chim. Acta
, vol.425
, pp. 169-175
-
-
Keeley, B.1
Stark, A.2
Pisanic, T.R.3
Kwak, R.4
Zhang, Y.5
Wrangle, J.6
Baylin, S.7
Herman, J.8
Ahuja, N.9
Brock, M.V.10
-
41
-
-
58749087364
-
Errors in the bisulfite conversion of DNA: Modulating inappropriate- and failed-conversion frequencies
-
Genereux, D. P., Johnson, W. C., Burden, A. F., Sẗoger, R. and Laird, C. D. (2008) Errors in the bisulfite conversion of DNA: modulating inappropriate- and failed-conversion frequencies. Nucleic Acids Res., 36, e150.
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. e150
-
-
Genereux, D.P.1
Johnson, W.C.2
Burden, A.F.3
Sẗoger, R.4
Laird, C.D.5
-
42
-
-
51649102357
-
Touchdown PCR for increased specificity and sensitivity in PCR amplification
-
Korbie, D. J. and Mattick, J. S. (2008) Touchdown PCR for increased specificity and sensitivity in PCR amplification. Nat. Protoc., 3, 1452-1456.
-
(2008)
Nat. Protoc.
, vol.3
, pp. 1452-1456
-
-
Korbie, D.J.1
Mattick, J.S.2
-
43
-
-
0033985151
-
Hypermethylation-associated inactivation of p14ARF Is independent of p16INK4a methylation and p53 mutational status
-
Esteller, M., Tortola, S., Toyota, M., Capella, G., Peinado, M. A., Baylin, S. B. and Herman, J. G. (2000) Hypermethylation-associated Inactivation of p14ARF Is Independent of p16INK4a Methylation and p53 Mutational Status. Cancer Res., 60, 129-133.
-
(2000)
Cancer Res.
, vol.60
, pp. 129-133
-
-
Esteller, M.1
Tortola, S.2
Toyota, M.3
Capella, G.4
Peinado, M.A.5
Baylin, S.B.6
Herman, J.G.7
-
45
-
-
77952966822
-
Single-tube analysis of DNA methylation with silica superparamagnetic beads
-
Bailey, V. J., Zhang, Y., Keeley, B. P., Yin, C., Pelosky, K. L., Brock, M., Baylin, S. B., Herman, J. G. and Wang, T.-H. (2010) Single-Tube Analysis of DNA Methylation with Silica Superparamagnetic Beads. Clin. Chem., 56, 1022-1025
-
(2010)
Clin. Chem.
, vol.56
, pp. 1022-1025
-
-
Bailey, V.J.1
Zhang, Y.2
Keeley, B.P.3
Yin, C.4
Pelosky, K.L.5
Brock, M.6
Baylin, S.B.7
Herman, J.G.8
Wang, T.-H.9
-
46
-
-
38649136194
-
Characterization of EvaGreen and the implication of its physicochemical properties for qPCR applications
-
Mao, F., Leung, W.-Y. and Xin, X. (2007) Characterization of EvaGreen and the implication of its physicochemical properties for qPCR applications. BMC Biotechnol., 7, 76.
-
(2007)
BMC Biotechnol.
, vol.7
, pp. 76
-
-
Mao, F.1
Leung, W.-Y.2
Xin, X.3
-
47
-
-
0032169516
-
The alternative product from the human CDKN2A locus, p14 (ARF), participates in a regulatory feedback loop with p53 and MDM2
-
Stott, F. J., Bates, S., James, M. C., McConnell, B. B., Starborg, M., Brookes, S., Palmero, I., Ryan, K., Hara, E., Vousden, K. H. et al. (1998) The alternative product from the human CDKN2A locus, p14 (ARF), participates in a regulatory feedback loop with p53 and MDM2. EMBO J., 17, 5001-5014.
-
(1998)
EMBO J.
, vol.17
, pp. 5001-5014
-
-
Stott, F.J.1
Bates, S.2
James, M.C.3
McConnell, B.B.4
Starborg, M.5
Brookes, S.6
Palmero, I.7
Ryan, K.8
Hara, E.9
Vousden, K.H.10
-
48
-
-
3242711153
-
CpG island methylation is responsible for p14ARF inactivation and inversely correlates with p53 overexpression in resected non-small cell lung cancer
-
Hsu, H.-S., Wang, Y.-C., Tseng, R.-C., Chang, J.-W., Chen, J.-T., Shih, C.-M., Chen, C.-Y. and Wang, Y.-C. (2004) CpG Island Methylation Is Responsible for p14ARF Inactivation and Inversely Correlates with p53 Overexpression in Resected Non-Small Cell Lung Cancer. Clin. Cancer Res., 10, 4734-4741.
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 4734-4741
-
-
Hsu, H.-S.1
Wang, Y.-C.2
Tseng, R.-C.3
Chang, J.-W.4
Chen, J.-T.5
Shih, C.-M.6
Chen, C.-Y.7
Wang, Y.-C.8
-
49
-
-
33847704518
-
Prognostic significance of RASSF1A promoter methylation on survival of non-small cell lung cancer patients treated with gemcitabine
-
Fischer, J. R., Ohnmacht, U., Rieger, N., Zemaitis, M., Stoffregen, C., Manegold, C. and Lahm, H. (2007) Prognostic significance of RASSF1A promoter methylation on survival of non-small cell lung cancer patients treated with gemcitabine. Lung Cancer, 56, 115-123.
-
(2007)
Lung Cancer
, vol.56
, pp. 115-123
-
-
Fischer, J.R.1
Ohnmacht, U.2
Rieger, N.3
Zemaitis, M.4
Stoffregen, C.5
Manegold, C.6
Lahm, H.7
-
50
-
-
84882269037
-
Antitumor impact of p14ARF on gefitinib-resistant non-small cell lung cancers
-
Saito, K., Takigawa, N., Ohtani, N., Iioka, H., Tomita, Y., Ueda, R., Fukuoka, J., Kuwahara, K., Ichihara, E., Kiura, K. et al. (2013) Antitumor Impact of p14ARF on Gefitinib-Resistant Non-Small Cell Lung Cancers. Mol. Cancer Ther., 12, 1616-1628.
-
(2013)
Mol. Cancer Ther.
, vol.12
, pp. 1616-1628
-
-
Saito, K.1
Takigawa, N.2
Ohtani, N.3
Iioka, H.4
Tomita, Y.5
Ueda, R.6
Fukuoka, J.7
Kuwahara, K.8
Ichihara, E.9
Kiura, K.10
-
51
-
-
78751629661
-
BRCA1 CpG island hypermethylation predicts sensitivity to poly (adenosine diphosphate) - Ribose polymerase inhibitors
-
Veeck, J., Ropero, S., Setien, F., Gonzalez-Suarez, E., Osorio, A., Benitez, J., Herman, J. G. and Esteller, M. (2010) BRCA1 CpG Island Hypermethylation Predicts Sensitivity to Poly (Adenosine Diphosphate) - Ribose Polymerase Inhibitors. J. Clin. Oncol., 28, e563-e564.
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. e563-e564
-
-
Veeck, J.1
Ropero, S.2
Setien, F.3
Gonzalez-Suarez, E.4
Osorio, A.5
Benitez, J.6
Herman, J.G.7
Esteller, M.8
-
52
-
-
84964533387
-
Epigenetic silencing of BRCA1 is linked to homologous recombination repair defects and elevated Mir-155 expression in myeloid neoplasms
-
Poh, W., Moliterno, A. R., Pratz, K. W., Gojo, I., McDevitt, M. A. and Herman, J. G. (2014) Epigenetic Silencing of BRCA1 Is Linked to Homologous Recombination Repair Defects and Elevated Mir-155 Expression in Myeloid Neoplasms. Blood, 124, 3525-3525.
-
(2014)
Blood
, vol.124
, pp. 3525
-
-
Poh, W.1
Moliterno, A.R.2
Pratz, K.W.3
Gojo, I.4
McDevitt, M.A.5
Herman, J.G.6
-
53
-
-
84899444670
-
Performance evaluation of kits for bisulfite-conversion of DNA from tissues, cell lines, FFPE tissues, aspirates, lavages, effusions, plasma, serum, and urine
-
Holmes, E. E., Jung, M., Meller, S., Leisse, A., Sailer, V., Zech, J., Mengdehl, M., Garbe, L.-A., Uhl, B., Kristiansen, G. et al. (2014) Performance Evaluation of Kits for Bisulfite-Conversion of DNA from Tissues, Cell Lines, FFPE Tissues, Aspirates, Lavages, Effusions, Plasma, Serum, and Urine. PLoS ONE, 9, e93933.
-
(2014)
PLoS ONE
, vol.9
, pp. e93933
-
-
Holmes, E.E.1
Jung, M.2
Meller, S.3
Leisse, A.4
Sailer, V.5
Zech, J.6
Mengdehl, M.7
Garbe, L.-A.8
Uhl, B.9
Kristiansen, G.10
-
54
-
-
0036311202
-
Identification and resolution of artifacts in bisulfite sequencing
-
Warnecke, P. M., Stirzaker, C., Song, J., Grunau, C., Melki, J. R. and Clark, S. J. (2002) Identification and resolution of artifacts in bisulfite sequencing. Methods, 27, 101-107.
-
(2002)
Methods
, vol.27
, pp. 101-107
-
-
Warnecke, P.M.1
Stirzaker, C.2
Song, J.3
Grunau, C.4
Melki, J.R.5
Clark, S.J.6
-
55
-
-
84964240053
-
Biological and therapeutic impact of intratumor heterogeneity in cancer evolution
-
McGranahan, N. and Swanton, C. (2015) Biological and Therapeutic Impact of Intratumor Heterogeneity in Cancer Evolution. Cancer Cell, 27, 15-26.
-
(2015)
Cancer Cell
, vol.27
, pp. 15-26
-
-
McGranahan, N.1
Swanton, C.2
-
56
-
-
69449096005
-
Heterogeneity in cancer: Cancer stem cells versus clonal evolution
-
Shackleton, M., Quintana, E., Fearon, E. R. and Morrison, S. J. (2009) Heterogeneity in Cancer: Cancer Stem Cells versus Clonal Evolution. Cell, 138, 822-829.
-
(2009)
Cell
, vol.138
, pp. 822-829
-
-
Shackleton, M.1
Quintana, E.2
Fearon, E.R.3
Morrison, S.J.4
-
57
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya, T., Morrison, S. J., Clarke, M. F. and Weissman, I. L. (2001) Stem cells, cancer, and cancer stem cells. Nature, 414, 105-111.
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
58
-
-
84858608410
-
Cancer stem cells: Impact, heterogeneity, and uncertainty
-
Magee, J. A., Piskounova, E. and Morrison, S. J. (2012) Cancer Stem Cells: Impact, Heterogeneity, and Uncertainty. Cancer Cell, 21, 283-296.
-
(2012)
Cancer Cell
, vol.21
, pp. 283-296
-
-
Magee, J.A.1
Piskounova, E.2
Morrison, S.J.3
-
59
-
-
0017167185
-
The clonal evolution of tumor cell populations
-
Nowell, P. C. (1976) The Clonal Evolution of Tumor Cell Populations. Science, 194, 23-28.
-
(1976)
Science
, vol.194
, pp. 23-28
-
-
Nowell, P.C.1
-
60
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj, M., Wicha, M. S., Benito-Hernandez, A., Morrison, S. J. and Clarke, M. F. (2003) Prospective identification of tumorigenic breast cancer cells. Proc. Nat. Acad. Sci., 100, 3983-3988.
-
(2003)
Proc. Nat. Acad. Sci.
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
61
-
-
33846095137
-
Identification and expansion of human colon-cancer-initiating cells
-
Ricci-Vitiani, L., Lombardi, D. G., Pilozzi, E., Biffoni, M., Todaro, M., Peschle, C. and De Maria, R. (2007) Identification and expansion of human colon-cancer-initiating cells. Nature, 445, 111-115.
-
(2007)
Nature
, vol.445
, pp. 111-115
-
-
Ricci-Vitiani, L.1
Lombardi, D.G.2
Pilozzi, E.3
Biffoni, M.4
Todaro, M.5
Peschle, C.6
De Maria, R.7
-
62
-
-
68149157845
-
Rapid analysis of heterogeneously methylated DNA using digital methylation-sensitive high resolution melting: Application to the CDKN2B (p15) gene
-
Candiloro, I., Mikeska, T., Hokland, P. and Dobrovic, A. (2008) Rapid analysis of heterogeneously methylated DNA using digital methylation-sensitive high resolution melting: application to the CDKN2B (p15) gene. Epigenetics & Chromatin, 1, 7.
-
(2008)
Epigenetics & Chromatin
, vol.1
, pp. 7
-
-
Candiloro, I.1
Mikeska, T.2
Hokland, P.3
Dobrovic, A.4
-
63
-
-
0032580320
-
Two-sided confidence intervals for the single proportion: Comparison of seven methods
-
Newcombe, R. G. (1998) Two-sided confidence intervals for the single proportion: comparison of seven methods. Stati. Med., 17, 857-872.
-
(1998)
Stati. Med.
, vol.17
, pp. 857-872
-
-
Newcombe, R.G.1
-
64
-
-
0342445442
-
Dynamic analysis of proviral induction and de novo methylation: Implications for a histone deacetylase-independent, methylation density-dependent mechanism of transcriptional repression
-
Lorincz, M. C., Schübeler, D., Goeke, S. C., Walters, M., Groudine, M. and Martin, D. I. K. (2000) Dynamic Analysis of Proviral Induction and De Novo Methylation: Implications for a Histone Deacetylase-Independent, Methylation Density-Dependent Mechanism of Transcriptional Repression. Mol. Cell. Biol., 20, 842-850.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 842-850
-
-
Lorincz, M.C.1
Schübeler, D.2
Goeke, S.C.3
Walters, M.4
Groudine, M.5
Martin, D.I.K.6
-
65
-
-
0033215453
-
P15Ink4B CpG island methylation in primary acute leukemia is heterogeneous and suggests density as a critical factor for transcriptional silencing
-
Cameron, E. E., Baylin, S. B. and Herman, J. G. (1999) p15INK4B CpG Island Methylation in Primary Acute Leukemia Is Heterogeneous and Suggests Density as a Critical Factor for Transcriptional Silencing. Blood, 94, 2445-2451.
-
(1999)
Blood
, vol.94
, pp. 2445-2451
-
-
Cameron, E.E.1
Baylin, S.B.2
Herman, J.G.3
-
66
-
-
33845799282
-
Prenatal diagnosis: Progress through plasma nucleic acids., Nat
-
Lo, Y. M. D. and Chiu, R. W. K. (2007) Prenatal diagnosis: progress through plasma nucleic acids., Nat. Rev. Genet., 8, 71-77.
-
(2007)
Rev. Genet.
, vol.8
, pp. 71-77
-
-
Lo, Y.M.D.1
Chiu, R.W.K.2
|