Time-resolved multimodal analysis of src homology 2 (SH2) domain binding in signaling by receptor tyrosine kinases

eLife

Volumn 5, Issue APRIL2016, 2016, Pages

  Jadwin, Joshua A ^a   Oh, Dongmyung ^a   Curran, Timothy G ^b,c   Ogiue Ikeda, Mari ^a   Jia, Lin ^a   White, Forest M ^b,c   Machida, Kazuya ^a   Yu, Ji ^a   Mayer, Bruce J ^a  

^a UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRK LIKE PROTEIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; PHOSPHOLIPASE C GAMMA1; PROTEIN SH2; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE SHP 2; PROTEIN BINDING;

ARTICLE; BINDING SITE; CELL PROLIFERATION ASSAY; CONTROLLED STUDY; FAR WESTERN BLOTTING; FLUORESCENCE MICROSCOPY; GENE ONTOLOGY; HUMAN; HUMAN CELL; IMMOBILIZED METAL AFFINITY CHROMATOGRAPHY; IMMUNOPRECIPITATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; WESTERN BLOTTING; CELL MEMBRANE; DRUG EFFECTS; EPITHELIUM CELL; FLUORESCENCE IMAGING; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAIN; TUMOR CELL LINE;

BLOTTING, FAR-WESTERN; CELL LINE, TUMOR; CELL MEMBRANE; EPIDERMAL GROWTH FACTOR; EPITHELIAL CELLS; HUMANS; MASS SPECTROMETRY; OPTICAL IMAGING; PROTEIN BINDING; RECEPTOR PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS;

EID: 84964545756     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.11835     Document Type: Article

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