Spatio-temporally precise activation of engineered receptor tyrosine kinases by light

EMBO Journal

Volumn 33, Issue 15, 2014, Pages 1713-1726

  Grusch, Michael ^a   Schelch, Karin ^a   Riedler, Robert ^b   Reichhart, Eva ^b   Differ, Christopher ^b   Berger, Walter ^a   Inglés Prieto, Álvaro ^b   Janovjak, Harald ^b  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA   (Austria)

Author keywords

aureochrome; cell signalling; light oxygen voltage (LOV) sensing domain; optogenetics; synthetic biology; synthetic physiology

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR 1; OXYGEN; PROTEIN TYROSINE KINASE;

ARTICLE; BLUE LIGHT; CONTROLLED STUDY; DIMERIZATION; ELECTRIC POTENTIAL; EMBRYO; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ENGINEERING; GENETIC TRANSFECTION; HEK293 CELL LINE; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; NONHUMAN; OPTOGENETICS; PHOTORECEPTOR; PRIORITY JOURNAL; STRAMENOPILE;

AUREOCHROME; CELL SIGNALLING; LIGHT-OXYGEN-VOLTAGE (LOV)-SENSING DOMAIN; OPTOGENETICS; SYNTHETIC BIOLOGY; SYNTHETIC PHYSIOLOGY;

ENZYME ACTIVATION; HEK293 CELLS; HUMANS; LIGHT; PHOSPHORYLATION; PROTEIN ENGINEERING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION;

EID: 84905385453     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201387695     Document Type: Article

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