-
1
-
-
84983123731
-
Epidemiological modifiers of non-alcoholic fatty liver disease: Focus on high-risk groups
-
Lonardo, A.; Bellentani, S.; Argo, C.K.; Ballestri, S.; Byrne, C.D.; Caldwell, S.H.; Cortez-Pinto, H.; Grieco, A.; Machado, M.V.; Miele, L.; et al. Epidemiological modifiers of non-alcoholic fatty liver disease: Focus on high-risk groups. Dig. Liver Dis. 2015, 47, 997-1006
-
(2015)
Dig. Liver Dis
, vol.47
, pp. 997-1006
-
-
Lonardo, A.1
Bellentani, S.2
Argo, C.K.3
Ballestri, S.4
Byrne, C.D.5
Caldwell, S.H.6
Cortez-Pinto, H.7
Grieco, A.8
Machado, M.V.9
Miele, L.10
-
2
-
-
33644547706
-
Nonalcoholic fatty liver disease: From steatosis to cirrhosis
-
Farrell, G.C.; Larter, C.Z. Nonalcoholic fatty liver disease: From steatosis to cirrhosis. Hepatology 2006, 43, S99-S112
-
(2006)
Hepatology
, vol.43
, pp. SS99-S112
-
-
Farrell, G.C.1
Larter, C.Z.2
-
3
-
-
84964499074
-
-
Hepatology
-
Younossi, Z.M.; Koenig, A.B.; Abdelatif, D.; Fazel, Y.; Henry, L.; Wymer, M. Global epidemiology of non-alcoholic fatty liver disease-meta-analytic assessment of prevalence, incidence and outcomes. Hepatology 2015
-
(2015)
Global Epidemiology of Non-Alcoholic Fatty Liver Disease-Meta-Analytic Assessment of Prevalence, Incidence and Outcomes
-
-
Younossi, Z.M.1
Koenig, A.B.2
Abdelatif, D.3
Fazel, Y.4
Henry, L.5
Wymer, M.6
-
4
-
-
84928540539
-
Role of ultrasound in the diagnosis and treatment of nonalcoholic fatty liver disease and its complications
-
Ballestri, S.; Romagnoli, D.; Nascimbeni, F.; Francica, G.; Lonardo, A. Role of ultrasound in the diagnosis and treatment of nonalcoholic fatty liver disease and its complications. Expert Rev. Gastroenterol. Hepatol. 2015, 9, 603-627
-
(2015)
Expert Rev. Gastroenterol. Hepatol
, vol.9
, pp. 603-627
-
-
Ballestri, S.1
Romagnoli, D.2
Nascimbeni, F.3
Francica, G.4
Lonardo, A.5
-
6
-
-
79960029926
-
Systematic review: The epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults
-
Vernon, G.; Baranova, A.; Younossi, Z.M. Systematic review: The epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults. Aliment. Pharmacol. Ther. 2011, 34, 274-285
-
(2011)
Aliment. Pharmacol. Ther
, vol.34
, pp. 274-285
-
-
Vernon, G.1
Baranova, A.2
Younossi, Z.M.3
-
7
-
-
79954507610
-
Genetic determinants of susceptibility and severity in nonalcoholic fatty liver disease
-
Daly, A.K.; Ballestri, S.; Carulli, L.; Loria, P.; Day, C.P. Genetic determinants of susceptibility and severity in nonalcoholic fatty liver disease. Expert Rev. Gastroenterol. Hepatol. 2011, 5, 253-263
-
(2011)
Expert Rev. Gastroenterol. Hepatol.
, vol.5
, pp. 253-263
-
-
Daly, A.K.1
Ballestri, S.2
Carulli, L.3
Loria, P.4
Day, C.P.5
-
8
-
-
67349174005
-
A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans
-
Kotronen, A.; Johansson, L.E.; Johansson, L.M.; Roos, C.; Westerbacka, J.; Hamsten, A.; Bergholm, R.; Arkkila, P.; Arola, J.; Kiviluoto, T.; et al. A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans. Diabetologia 2009, 52, 1056-1060
-
(2009)
Diabetologia
, vol.52
, pp. 1056-1060
-
-
Kotronen, A.1
Johansson, L.E.2
Johansson, L.M.3
Roos, C.4
Westerbacka, J.5
Hamsten, A.6
Bergholm, R.7
Arkkila, P.8
Arola, J.9
Kiviluoto, T.10
-
9
-
-
84869843235
-
PNPLA3, the triacylglycerol synthesis/hydrolysis/storage dilemma, and nonalcoholic fatty liver disease
-
Sookoian, S.; Pirola, C.J. PNPLA3, the triacylglycerol synthesis/hydrolysis/storage dilemma, and nonalcoholic fatty liver disease. World J. Gastroenterol. 2012, 18, 6018-6026
-
(2012)
World J. Gastroenterol
, vol.18
, pp. 6018-6026
-
-
Sookoian, S.1
Pirola, C.J.2
-
10
-
-
10344262633
-
Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities
-
Jenkins, C.M.; Mancuso, D.J.; Yan, W.; Sims, H.F.; Gibson, B.; Gross, R.W. Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities. J. Biol. Chem. 2004, 279, 48968-48975
-
(2004)
J. Biol. Chem
, vol.279
, pp. 48968-48975
-
-
Jenkins, C.M.1
Mancuso, D.J.2
Yan, W.3
Sims, H.F.4
Gibson, B.5
Gross, R.W.6
-
11
-
-
27444433258
-
Expression, regulation, and triglyceride hydrolase activity of Adiponutrin family members
-
Lake, A.C.; Sun, Y.; Li, J.L.; Kim, J.E.; Johnson, J.W.; Li, D.; Revett, T.; Shih, H.H.; Liu, W.; Paulsen, J.E.; et al. Expression, regulation, and triglyceride hydrolase activity of Adiponutrin family members. J. Lipid Res. 2005, 46, 2477-2487
-
(2005)
J. Lipid Res
, vol.46
, pp. 2477-2487
-
-
Lake, A.C.1
Sun, Y.2
Li, J.L.3
Kim, J.E.4
Johnson, J.W.5
Li, D.6
Revett, T.7
Shih, H.H.8
Liu, W.9
Paulsen, J.E.10
-
12
-
-
56749096610
-
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
-
Romeo, S.; Kozlitina, J.; Xing, C.; Pertsemlidis, A.; Cox, D.; Pennacchio, L.A.; Boerwinkle, E.; Cohen, J.C.; Hobbs, H.H. Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease. Nat. Genet. 2008, 40, 1461-1465
-
(2008)
Nat. Genet
, vol.40
, pp. 1461-1465
-
-
Romeo, S.1
Kozlitina, J.2
Xing, C.3
Pertsemlidis, A.4
Cox, D.5
Pennacchio, L.A.6
Boerwinkle, E.7
Cohen, J.C.8
Hobbs, H.H.9
-
13
-
-
77956636268
-
The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease
-
Rotman, Y.; Koh, C.; Zmuda, J.M.; Kleiner, D.E.; Liang, T.J. The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease. Hepatology 2010, 52, 894-903
-
(2010)
Hepatology
, vol.52
, pp. 894-903
-
-
Rotman, Y.1
Koh, C.2
Zmuda, J.M.3
Kleiner, D.E.4
Liang, T.J.5
-
14
-
-
77957936457
-
I148M patatin-like phospholipase domain-containing 3 gene variant and severity of pediatric nonalcoholic fatty liver disease
-
Valenti, L.; Alisi, A.; Galmozzi, E.; Bartuli, A.; Del Menico, B.; Alterio, A.; Dongiovanni, P.; Fargion, S.; Nobili, V. I148M patatin-like phospholipase domain-containing 3 gene variant and severity of pediatric nonalcoholic fatty liver disease. Hepatology 2010, 52, 1274-1280
-
(2010)
Hepatology
, vol.52
, pp. 1274-1280
-
-
Valenti, L.1
Alisi, A.2
Galmozzi, E.3
Bartuli, A.4
Del Menico, B.5
Alterio, A.6
Dongiovanni, P.7
Fargion, S.8
Nobili, V.9
-
15
-
-
79957462315
-
Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease
-
Sookoian, S.; Pirola, C.J. Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease. Hepatology 2011, 53, 1883-1894
-
(2011)
Hepatology
, vol.53
, pp. 1883-1894
-
-
Sookoian, S.1
Pirola, C.J.2
-
16
-
-
79959562237
-
Variant adiponutrin (PNPLA3) represents a common fibrosis risk gene: Non-invasive elastography-based study in chronic liver disease
-
Krawczyk, M.; Grünhage, F.; Zimmer, V.; Lammert, F. Variant adiponutrin (PNPLA3) represents a common fibrosis risk gene: Non-invasive elastography-based study in chronic liver disease. J. Hepatol. 2011, 55, 299-306
-
(2011)
J. Hepatol
, vol.55
, pp. 299-306
-
-
Krawczyk, M.1
Grünhage, F.2
Zimmer, V.3
Lammert, F.4
-
17
-
-
77950607738
-
Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease
-
Valenti, L.; Al-Serri, A.; Daly, A.K.; Galmozzi, E.; Rametta, R.; Dongiovanni, P.; Nobili, V.; Mozzi, E.; Roviaro, G.; Vanni, E.; et al. Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease. Hepatology 2010, 51, 1209-1217
-
(2010)
Hepatology
, vol.51
, pp. 1209-1217
-
-
Valenti, L.1
Al-Serri, A.2
Daly, A.K.3
Galmozzi, E.4
Rametta, R.5
Dongiovanni, P.6
Nobili, V.7
Mozzi, E.8
Roviaro, G.9
Vanni, E.10
-
18
-
-
84862765487
-
A multi-ethnic study of a PNPLA3 gene variant and its association with disease severity in non-alcoholic fatty liver disease
-
Zain, S.M.; Mohamed, R.; Mahadeva, S.; Cheah, P.L.; Rampal, S.; Basu, R.C.; Mohamed, Z. A multi-ethnic study of a PNPLA3 gene variant and its association with disease severity in non-alcoholic fatty liver disease. Hum. Genet. 2012, 131, 1145-1152
-
(2012)
Hum. Genet
, vol.131
, pp. 1145-1152
-
-
Zain, S.M.1
Mohamed, R.2
Mahadeva, S.3
Cheah, P.L.4
Rampal, S.5
Basu, R.C.6
Mohamed, Z.7
-
19
-
-
84951083544
-
The genetic variant I148M in PNPLA3 is associated with increased hepatic retinyl-palmitate storage in humans
-
Kovarova, M.; Königsrainer, I.; Königsrainer, A.; Machicao, F.; Häring, H.-U.; Schleicher, E.; Peter, A. The genetic variant I148M in PNPLA3 is associated with increased hepatic retinyl-palmitate storage in humans. J. Clin. Endocrinol. Metab. 2015, 100, E1568-E1574
-
(2015)
J. Clin. Endocrinol. Metab
, vol.100
, pp. E1568-E1574
-
-
Kovarova, M.1
Königsrainer, I.2
Königsrainer, A.3
Machicao, F.4
Häring, H.-U.5
Schleicher, E.6
Peter, A.7
-
20
-
-
84903996547
-
PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells
-
Pirazzi, C.; Valenti, L.; Motta, B.M.; Pingitore, P.; Hedfalk, K.; Mancina, R.M.; Burza, M.A.; Indiveri, C.; Ferro, Y.; Montalcini, T.; et al. PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells. Hum. Mol. Genet. 2014, 23, 4077-4085
-
(2014)
Hum. Mol. Genet.
, vol.23
, pp. 4077-4085
-
-
Pirazzi, C.1
Valenti, L.2
Motta, B.M.3
Pingitore, P.4
Hedfalk, K.5
Mancina, R.M.6
Burza, M.A.7
Indiveri, C.8
Ferro, Y.9
Montalcini, T.10
-
21
-
-
84877347936
-
PNPLA3/adiponutrin functions in lipid droplet formation
-
Chamoun, Z.; Vacca, F.; Parton, R.G.; Gruenberg, J. PNPLA3/adiponutrin functions in lipid droplet formation. Biol. Cell 2013, 105, 219-233
-
(2013)
Biol. Cell
, vol.105
, pp. 219-233
-
-
Chamoun, Z.1
Vacca, F.2
Parton, R.G.3
Gruenberg, J.4
-
22
-
-
84897430331
-
PNPLA3 mediates hepatocyte triacylglycerol remodelling
-
Ruhanen, H.; Perttilä, J.; Hölttä-Vuori, M.; Zhou, Y.; Yki-Järvinen, H.; Ikonen, E.; Käkelä, R.; Olkkonen, V.M. PNPLA3 mediates hepatocyte triacylglycerol remodelling. J. Lipid Res. 2014, 55, 739-746
-
(2014)
J. Lipid Res
, vol.55
, pp. 739-746
-
-
Ruhanen, H.1
Perttilä, J.2
Hölttä-Vuori, M.3
Zhou, Y.4
Yki-Järvinen, H.5
Ikonen, E.6
Käkelä, R.7
Olkkonen, V.M.8
-
23
-
-
84903625185
-
Metabolic profiling reveals that PNPLA3 induces widespread effects on metabolism beyond triacylglycerol remodeling in Huh-7 hepatoma cells
-
Min, H.-K.; Sookoian, S.; Pirola, C.J.; Cheng, J.; Mirshahi, F.; Sanyal, A.J. Metabolic profiling reveals that PNPLA3 induces widespread effects on metabolism beyond triacylglycerol remodeling in Huh-7 hepatoma cells. Am. J. Physiol. Gastrointest. Liver Physiol. 2014, 307, G66-G76
-
(2014)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.307
, pp. G66-G76
-
-
Min, H.-K.1
Sookoian, S.2
Pirola, C.J.3
Cheng, J.4
Mirshahi, F.5
Sanyal, A.J.6
-
24
-
-
84964511310
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini, Y.; Hochberg, Y. Controlling the false discovery rate: A practical and powerful approach to multiple testing. J. R. Stat. Soc. B 1995, 57, 289-300.
-
(1995)
J. R. Stat. Soc. B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
25
-
-
84914178553
-
Altered fatty acid metabolism-related gene expression in liver from morbidly obese women with non-alcoholic fatty liver disease
-
Auguet, T.; Berlanga, A.; Guiu-Jurado, E.; Martinez, S.; Porras, J.A.; Aragonès, G.; Sabench, F.; Hernandez, M.; Aguilar, C.; Sirvent, J.J.; et al. Altered fatty acid metabolism-related gene expression in liver from morbidly obese women with non-alcoholic fatty liver disease. Int. J. Mol. Sci. 2014, 15, 22173-22187
-
(2014)
Int. J. Mol. Sci.
, vol.15
, pp. 22173-22187
-
-
Auguet, T.1
Berlanga, A.2
Guiu-Jurado, E.3
Martinez, S.4
Porras, J.A.5
Aragonès, G.6
Sabench, F.7
Hernandez, M.8
Aguilar, C.9
Sirvent, J.J.10
-
26
-
-
84896939136
-
Genetic variants in GCKR and PNPLA3 confer susceptibility to nonalcoholic fatty liver disease in obese individuals
-
Lin, Y.-C.; Chang, P.-F.; Chang, M.-H.; Ni, Y.-H. Genetic variants in GCKR and PNPLA3 confer susceptibility to nonalcoholic fatty liver disease in obese individuals. Am. J. Clin. Nutr. 2014, 99, 869-874
-
(2014)
Am. J. Clin. Nutr.
, vol.99
, pp. 869-874
-
-
Lin, Y.-C.1
Chang, P.-F.2
Chang, M.-H.3
Ni, Y.-H.4
-
27
-
-
84929515461
-
[Association between patatin-like phospholipase domain-containing protein 3 gene rs738409 polymorphism and non-alcoholic fatty liver disease susceptibility: A meta-analysis]
-
Wu, P.; Shu, Y.; Guo, F.; Luo, H.; Zhang, G.; Tan, S. [Association between patatin-like phospholipase domain-containing protein 3 gene rs738409 polymorphism and non-alcoholic fatty liver disease susceptibility: A meta-analysis]. Zhonghua Liu Xing Bing Xue Za Zhi 2015, 36, 78-82.
-
(2015)
Zhonghua Liu Xing Bing Xue Za Zhi
, vol.36
, pp. 78-82
-
-
Wu, P.1
Shu, Y.2
Guo, F.3
Luo, H.4
Zhang, G.5
Tan, S.6
-
28
-
-
84925260735
-
Association between patatin-like phospholipase domain containing 3 gene (PNPLA3) polymorphisms and nonalcoholic fatty liver disease: A HuGE review and meta-analysis
-
Xu, R.; Tao, A.; Zhang, S.; Deng, Y.; Chen, G. Association between patatin-like phospholipase domain containing 3 gene (PNPLA3) polymorphisms and nonalcoholic fatty liver disease: A HuGE review and meta-analysis. Sci. Rep. 2015, 5, 9284
-
(2015)
Sci. Rep
, vol.5
-
-
Xu, R.1
Tao, A.2
Zhang, S.3
Deng, Y.4
Chen, G.5
-
29
-
-
84926635029
-
PNPLA3 polymorphisms (Rs738409) and non-alcoholic fatty liver disease risk and related phenotypes: A meta-analysis
-
Zhang, L.; You, W.; Zhang, H.; Peng, R.; Zhu, Q.; Yao, A.; Li, X.; Zhou, Y.; Wang, X.; Pu, L.; et al. PNPLA3 polymorphisms (rs738409) and non-alcoholic fatty liver disease risk and related phenotypes: A meta-analysis. J. Gastroenterol. Hepatol. 2015, 30, 821-829
-
(2015)
J. Gastroenterol. Hepatol.
, vol.30
, pp. 821-829
-
-
Zhang, L.1
You, W.2
Zhang, H.3
Peng, R.4
Zhu, Q.5
Yao, A.6
Li, X.7
Zhou, Y.8
Wang, X.9
Pu, L.10
-
30
-
-
84924603398
-
A genetic risk score is associated with hepatic triglyceride content and non-alcoholic steatohepatitis in Mexicans with morbid obesity
-
León-Mimila, P.; Vega-Badillo, J.; Gutiérrez-Vidal, R.; Villamil-Ramírez, H.; Villareal-Molina, T.; Larrieta-Carrasco, E.; López-Contreras, B.E.; Kauffer, L.R.M.; Maldonado-Pintado, D.G.; Méndez-Sánchez, N.; et al. A genetic risk score is associated with hepatic triglyceride content and non-alcoholic steatohepatitis in Mexicans with morbid obesity. Exp. Mol. Pathol. 2015, 98, 178-183
-
(2015)
Exp. Mol. Pathol.
, vol.98
, pp. 178-183
-
-
León-Mimila, P.1
Vega-Badillo, J.2
Gutiérrez-Vidal, R.3
Villamil-Ramírez, H.4
Villareal-Molina, T.5
Larrieta-Carrasco, E.6
López-Contreras, B.E.7
Kauffer, L.R.M.8
Maldonado-Pintado, D.G.9
Méndez-Sánchez, N.10
-
31
-
-
84907835097
-
Association between the PNPLA3 I148M polymorphism and non-alcoholic fatty liver disease in the Uygur and Han ethnic groups of northwestern China
-
Zhang, Y.; Cai, W.; Song, J.; Miao, L.; Zhang, B.; Xu, Q.; Zhang, L.; Yao, H. Association between the PNPLA3 I148M polymorphism and non-alcoholic fatty liver disease in the Uygur and Han ethnic groups of northwestern China. PLoS ONE 2014, 9, e108381
-
(2014)
Plos ONE
, vol.9
-
-
Zhang, Y.1
Cai, W.2
Song, J.3
Miao, L.4
Zhang, B.5
Xu, Q.6
Zhang, L.7
Yao, H.8
-
32
-
-
84938082463
-
PNPLA3 genotype increases susceptibility of nonalcoholic steatohepatitis among obese patients with nonalcoholic fatty liver disease
-
Tai, C.-M.; Huang, C.-K.; Tu, H.-P.; Hwang, J.-C.; Chang, C.-Y.; Yu, M.-L. PNPLA3 genotype increases susceptibility of nonalcoholic steatohepatitis among obese patients with nonalcoholic fatty liver disease. Surg. Obes. Relat. Dis. 2014, 11, 888-894
-
(2014)
Surg. Obes. Relat. Dis
, vol.11
, pp. 888-894
-
-
Tai, C.-M.1
Huang, C.-K.2
Tu, H.-P.3
Hwang, J.-C.4
Chang, C.-Y.5
Yu, M.-L.6
-
33
-
-
84912525645
-
Role of the PNPLA3 I148M polymorphism in nonalcoholic fatty liver disease and fibrosis in Korea
-
Lee, S.S.; Byoun, Y.-S.; Jeong, S.-H.; Woo, B.H.; Jang, E.S.; Kim, J.-W.; Kim, H.Y. Role of the PNPLA3 I148M polymorphism in nonalcoholic fatty liver disease and fibrosis in Korea. Dig. Dis. Sci. 2014, 59, 2967-2974
-
(2014)
Dig. Dis. Sci.
, vol.59
, pp. 2967-2974
-
-
Lee, S.S.1
Byoun, Y.-S.2
Jeong, S.-H.3
Woo, B.H.4
Jang, E.S.5
Kim, J.-W.6
Kim, H.Y.7
-
34
-
-
84929347096
-
Paradoxical dissociation between hepatic fat content and de novo lipogenesis due to PNPLA3 sequence variant
-
Margherita Mancina, R.; Matikainen, N.; Maglio, C.; Söderlund, S.; Lundbom, N.; Hakkarainen, A.; Rametta, R.; Mozzi, E.; Fargion, S.; Valenti, L.; et al. Paradoxical dissociation between hepatic fat content and de novo lipogenesis due to PNPLA3 sequence variant. J. Clin. Endocrinol. Metab. 2015, 100, E821-E825
-
(2015)
J. Clin. Endocrinol. Metab.
, vol.100
, pp. E821-E825
-
-
Margherita Mancina, R.1
Matikainen, N.2
Maglio, C.3
Söderlund, S.4
Lundbom, N.5
Hakkarainen, A.6
Rametta, R.7
Mozzi, E.8
Fargion, S.9
Valenti, L.10
-
35
-
-
84941910908
-
GWAS-identified common variants with nonalcoholic fatty liver disease in chinese children
-
Shang, X.R.; Song, J.Y.; Liu, F.H.; Ma, J.; Wang, H.J. GWAS-identified common variants with nonalcoholic fatty liver disease in chinese children. J. Pediatr. Gastroenterol. Nutr. 2015, 60, 669-674
-
(2015)
J. Pediatr. Gastroenterol. Nutr
, vol.60
, pp. 669-674
-
-
Shang, X.R.1
Song, J.Y.2
Liu, F.H.3
Ma, J.4
Wang, H.J.5
-
36
-
-
84899486785
-
Influence of dietary pattern, physical activity, and I148M PNPLA3 on steatosis severity in at-risk adolescents
-
Nobili, V.; Liccardo, D.; Bedogni, G.; Salvatori, G.; Gnani, D.; Bersani, I.; Alisi, A.; Valenti, L.; Raponi, M. Influence of dietary pattern, physical activity, and I148M PNPLA3 on steatosis severity in at-risk adolescents. Genes Nutr. 2014, 9, 392
-
(2014)
Genes Nutr
, vol.9
-
-
Nobili, V.1
Liccardo, D.2
Bedogni, G.3
Salvatori, G.4
Gnani, D.5
Bersani, I.6
Alisi, A.7
Valenti, L.8
Raponi, M.9
-
37
-
-
84954290324
-
The rs2294918 E434K variant modulates patatin-like phospholipase domain-containing 3 expression and liver damage
-
Donati, B.; Motta, B.M.; Pingitore, P.; Meroni, M.; Pietrelli, A.; Alisi, A.; Petta, S.; Xing, C.; Dongiovanni, P.; del Menico, B.; et al. The rs2294918 E434K variant modulates patatin-like phospholipase domain-containing 3 expression and liver damage. Hepatology 2016, 63, 787-798
-
(2016)
Hepatology
, vol.63
, pp. 787-798
-
-
Donati, B.1
Motta, B.M.2
Pingitore, P.3
Meroni, M.4
Pietrelli, A.5
Alisi, A.6
Petta, S.7
Xing, C.8
Dongiovanni, P.9
Del Menico, B.10
-
38
-
-
84924772254
-
Altered hepatic gene expression in nonalcoholic fatty liver disease is associated with lower hepatic n-3 and n-6 polyunsaturated fatty acids
-
Arendt, B.M.; Comelli, E.M.; Ma, D.W.L.; Lou, W.; Teterina, A.; Kim, T.; Fung, S.K.; Wong, D.K.H.; McGilvray, I.; Fischer, S.E.; et al. Altered hepatic gene expression in nonalcoholic fatty liver disease is associated with lower hepatic n-3 and n-6 polyunsaturated fatty acids. Hepatology 2015, 61, 1565-1578
-
(2015)
Hepatology
, vol.61
, pp. 1565-1578
-
-
Arendt, B.M.1
Comelli, E.M.2
Ma, D.W.L.3
Lou, W.4
Teterina, A.5
Kim, T.6
Fung, S.K.7
Wong, D.K.H.8
McGilvray, I.9
Fischer, S.E.10
-
39
-
-
84942833417
-
Targeted-bisulfite sequence analysis of the methylation of CpG islands in genes encoding PNPLA3, SAMM50, and PARVB of patients with non-alcoholic fatty liver disease
-
Kitamoto, T.; Kitamoto, A.; Ogawa, Y.; Honda, Y.; Imajo, K.; Saito, S.; Yoneda, M.; Nakamura, T.; Nakajima, A.; Hotta, K. Targeted-bisulfite sequence analysis of the methylation of CpG islands in genes encoding PNPLA3, SAMM50, and PARVB of patients with non-alcoholic fatty liver disease. J. Hepatol. 2015, 63, 494-502
-
(2015)
J. Hepatol
, vol.63
, pp. 494-502
-
-
Kitamoto, T.1
Kitamoto, A.2
Ogawa, Y.3
Honda, Y.4
Imajo, K.5
Saito, S.6
Yoneda, M.7
Nakamura, T.8
Nakajima, A.9
Hotta, K.10
-
40
-
-
84908250676
-
Shifts in dietary carbohydrate-lipid exposure regulate expression of the non-alcoholic fatty liver disease-associated gene PNPLA3/adiponutrin in mouse liver and HepG2 human liver cells
-
Hao, L.; Ito, K.; Huang, K.H.; Sae-tan, S.; Lambert, J.D.; Ross, A.C. Shifts in dietary carbohydrate-lipid exposure regulate expression of the non-alcoholic fatty liver disease-associated gene PNPLA3/adiponutrin in mouse liver and HepG2 human liver cells. Metabolism 2014, 63, 1352-1362
-
(2014)
Metabolism
, vol.63
, pp. 1352-1362
-
-
Hao, L.1
Ito, K.2
Huang, K.H.3
Sae-Tan, S.4
Lambert, J.D.5
Ross, A.C.6
-
41
-
-
77952409634
-
A feed-forward loop amplifies nutritional regulation of PNPLA3
-
Huang, Y.; He, S.; Li, J.Z.; Seo, Y.-K.; Osborne, T.F.; Cohen, J.C.; Hobbs, H.H. A feed-forward loop amplifies nutritional regulation of PNPLA3. Proc. Natl. Acad. Sci. USA 2010, 107, 7892-7897
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 7892-7897
-
-
Huang, Y.1
He, S.2
Li, J.Z.3
Seo, Y.-K.4
Osborne, T.F.5
Cohen, J.C.6
Hobbs, H.H.7
-
42
-
-
84858701950
-
The interaction of hepatic lipid and glucose metabolism in liver diseases
-
Bechmann, L.P.; Hannivoort, R.A.; Gerken, G.; Hotamisligil, G.S.; Trauner, M.; Canbay, A. The interaction of hepatic lipid and glucose metabolism in liver diseases. J. Hepatol. 2012, 56, 952-964
-
(2012)
J. Hepatol
, vol.56
, pp. 952-964
-
-
Bechmann, L.P.1
Hannivoort, R.A.2
Gerken, G.3
Hotamisligil, G.S.4
Trauner, M.5
Canbay, A.6
-
43
-
-
84898600202
-
Receptor activation increases hepatic fatty acid desaturation by the induction of SCD1 expression through an LXRα-SREBP1c-dependent mechanism
-
Zhang, X.; Liu, J.; Su, W.; Wu, J.; Wang, C.; Kong, X.; Gustafsson, J.-Å.; Ding, J.; Ma, X.; Guan, Y. Liver X receptor activation increases hepatic fatty acid desaturation by the induction of SCD1 expression through an LXRα-SREBP1c-dependent mechanism. J. Diabetes 2014, 6, 212-220
-
(2014)
J. Diabetes
, vol.6
, pp. 212-220
-
-
Zhang, X.1
Liu, J.2
Su, W.3
Wu, J.4
Wang, C.5
Kong, X.6
Gustafsson, J.-Å.7
Ding, J.8
Ma, X.9
Guan, Y.10
Liver, X.11
-
44
-
-
84963677654
-
The role of nuclear receptors in the pathophysiology, natural course, and drug treatment of NAFLD in humans
-
Ballestri, S.; Nascimbeni, F.; Romagnoli, D.; Baldelli, E.; Lonardo, A. The role of nuclear receptors in the pathophysiology, natural course, and drug treatment of NAFLD in humans. Adv. Ther. 2016, 33, 291-319
-
(2016)
Adv. Ther
, vol.33
, pp. 291-319
-
-
Ballestri, S.1
Nascimbeni, F.2
Romagnoli, D.3
Baldelli, E.4
Lonardo, A.5
-
45
-
-
79958863581
-
Distinct regulation of adiponutrin/PNPLA3 gene expression by the transcription factors ChREBP and SREBP1c in mouse and human hepatocytes
-
Dubuquoy, C.; Robichon, C.; Lasnier, F.; Langlois, C.; Dugail, I.; Foufelle, F.; Girard, J.; Burnol, A.F.; Postic, C.; Moldes, M. Distinct regulation of adiponutrin/PNPLA3 gene expression by the transcription factors ChREBP and SREBP1c in mouse and human hepatocytes. J. Hepatol. 2011, 55, 145-153
-
(2011)
J. Hepatol
, vol.55
, pp. 145-153
-
-
Dubuquoy, C.1
Robichon, C.2
Lasnier, F.3
Langlois, C.4
Dugail, I.5
Foufelle, F.6
Girard, J.7
Burnol, A.F.8
Postic, C.9
Moldes, M.10
-
46
-
-
84923067081
-
Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease
-
Pawlak, M.; Lefebvre, P.; Staels, B. Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease. J. Hepatol. 2015, 62, 720-733
-
(2015)
J. Hepatol
, vol.62
, pp. 720-733
-
-
Pawlak, M.1
Lefebvre, P.2
Staels, B.3
-
47
-
-
84874633665
-
Peroxisome proliferator-activated receptor genetic polymorphisms and nonalcoholic Fatty liver disease: Any role in disease susceptibility?
-
Dongiovanni, P.; Valenti, L. Peroxisome proliferator-activated receptor genetic polymorphisms and nonalcoholic Fatty liver disease: Any role in disease susceptibility? PPAR Res. 2013, 2013, 452061
-
(2013)
PPAR Res
, vol.2013
-
-
Dongiovanni, P.1
Valenti, L.2
-
48
-
-
84872493396
-
Cholesterol metabolism and the pathogenesis of non-alcoholic steatohepatitis
-
Musso, G.; Gambino, R.; Cassader, M. Cholesterol metabolism and the pathogenesis of non-alcoholic steatohepatitis. Prog. Lipid Res. 2013, 52, 175-191
-
(2013)
Prog. Lipid Res
, vol.52
, pp. 175-191
-
-
Musso, G.1
Gambino, R.2
Cassader, M.3
-
49
-
-
84860469242
-
Increased hepatic synthesis and dysregulation of cholesterol metabolism is associated with the severity of nonalcoholic fatty liver disease
-
Min, H.-K.; Kapoor, A.; Fuchs, M.; Mirshahi, F.; Zhou, H.; Maher, J.; Kellum, J.; Warnick, R.; Contos, M.J.; Sanyal, A.J. Increased hepatic synthesis and dysregulation of cholesterol metabolism is associated with the severity of nonalcoholic fatty liver disease. Cell Metab. 2012, 15, 665-674
-
(2012)
Cell Metab
, vol.15
, pp. 665-674
-
-
Min, H.-K.1
Kapoor, A.2
Fuchs, M.3
Mirshahi, F.4
Zhou, H.5
Maher, J.6
Kellum, J.7
Warnick, R.8
Contos, M.J.9
Sanyal, A.J.10
-
50
-
-
84873952903
-
Liver lipocalin 2 expression in severely obese women with non alcoholic fatty liver disease
-
Auguet, T.; Terra, X.; Quintero, Y.; Martínez, S.; Manresa, N.; Porras, J.A.; Aguilar, C.; Orellana-Gavaldà, J.M.; Hernández, M.; Sabench, F.; et al. Liver lipocalin 2 expression in severely obese women with non alcoholic fatty liver disease. Exp. Clin. Endocrinol. Diabetes 2013, 121, 119-124
-
(2013)
Exp. Clin. Endocrinol. Diabetes
, vol.121
, pp. 119-124
-
-
Auguet, T.1
Terra, X.2
Quintero, Y.3
Martínez, S.4
Manresa, N.5
Porras, J.A.6
Aguilar, C.7
Orellana-Gavaldà, J.M.8
Hernández, M.9
Sabench, F.10
-
51
-
-
78651232349
-
Inhibition of the proliferation and invasion of hepatocellular carcinoma cells by lipocalin 2 through blockade of JNK and PI3K/Akt signaling
-
Lee, E.-K.; Kim, H.-J.; Lee, K.-J.; Lee, H.-J.; Lee, J.-S.; Kim, D.-G.; Hong, S.-W.; Yoon, Y.; Kim, J.-S. Inhibition of the proliferation and invasion of hepatocellular carcinoma cells by lipocalin 2 through blockade of JNK and PI3K/Akt signaling. Int. J. Oncol. 2011, 38, 325-333
-
(2011)
Int. J. Oncol
, vol.38
, pp. 325-333
-
-
Lee, E.-K.1
Kim, H.-J.2
Lee, K.-J.3
Lee, H.-J.4
Lee, J.-S.5
Kim, D.-G.6
Hong, S.-W.7
Yoon, Y.8
Kim, J.-S.9
-
52
-
-
84860465005
-
Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase
-
Kumari, M.; Schoiswohl, G.; Chitraju, C.; Paar, M.; Rangrez, A.Y.; Wongsiriroj, N.; Nagy, H.M.; Pavlina, T.; Scott, S.A.; Knittelfelder, O.; et al. Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase. Cell Metab. 2012, 15, 691-702
-
(2012)
Cell Metab
, vol.15
, pp. 691-702
-
-
Kumari, M.1
Schoiswohl, G.2
Chitraju, C.3
Paar, M.4
Rangrez, A.Y.5
Wongsiriroj, N.6
Nagy, H.M.7
Pavlina, T.8
Scott, S.A.9
Knittelfelder, O.10
-
53
-
-
84921476396
-
PNPLA3 I148M variant in nonalcoholic fatty liver disease: Demographic and ethnic characteristics and the role of the variant in nonalcoholic fatty liver fibrosis
-
Chen, L.Z.; Xin, Y.N.; Geng, N.; Jiang, M.; Zhang, D.D.; Xuan, S.Y. PNPLA3 I148M variant in nonalcoholic fatty liver disease: Demographic and ethnic characteristics and the role of the variant in nonalcoholic fatty liver fibrosis. World J. Gastroenterol. 2015, 21, 794-802.
-
(2015)
World J. Gastroenterol
, vol.21
, pp. 794-802
-
-
Chen, L.Z.1
Xin, Y.N.2
Geng, N.3
Jiang, M.4
Zhang, D.D.5
Xuan, S.Y.6
-
54
-
-
20044374023
-
Design and validation of a histological scoring system for nonalcoholic fatty liver disease
-
Kleiner, D.E.; Brunt, E.M.; Van Natta, M.; Behling, C.; Contos, M.J.; Cummings, O.W.; Ferrell, L.D.; Liu, Y.-C.; Torbenson, M.S.; Unalp-Arida, A.; et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 2005, 41, 1313-1321
-
(2005)
Hepatology
, vol.41
, pp. 1313-1321
-
-
Kleiner, D.E.1
Brunt, E.M.2
Van Natta, M.3
Behling, C.4
Contos, M.J.5
Cummings, O.W.6
Ferrell, L.D.7
Liu, Y.-C.8
Torbenson, M.S.9
Unalp-Arida, A.10
-
55
-
-
0033200054
-
Nonalcoholic steatohepatitis: A proposal for grading and staging the histological lesions
-
Brunt, E.M.; Janney, C.G.; Di Bisceglie, A.M.; Neuschwander-Tetri, B.A.; Bacon, B.R. Nonalcoholic steatohepatitis: A proposal for grading and staging the histological lesions. Am. J. Gastroenterol. 1999, 94, 2467-2474
-
(1999)
Am. J. Gastroenterol
, vol.94
, pp. 2467-2474
-
-
Brunt, E.M.1
Janney, C.G.2
Di Bisceglie, A.M.3
Neuschwander-Tetri, B.A.4
Bacon, B.R.5
-
56
-
-
79953249421
-
FABP 4 is associated with inflammatory markers and metabolic syndrome in morbidly obese women
-
Terra, X.; Quintero, Y.; Auguet, T.; Porras, J.A.; Hernández, M.; Sabench, F.; Aguilar, C.; Luna, A.M.; Del Castillo, D.; Richart, C. FABP 4 is associated with inflammatory markers and metabolic syndrome in morbidly obese women. Eur. J. Endocrinol. 2011, 164, 539-547
-
(2011)
Eur. J. Endocrinol
, vol.164
, pp. 539-547
-
-
Terra, X.1
Quintero, Y.2
Auguet, T.3
Porras, J.A.4
Hernández, M.5
Sabench, F.6
Aguilar, C.7
Luna, A.M.8
Del Castillo, D.9
Richart, C.10
|