Shifts in dietary carbohydrate-lipid exposure regulate expression of the non-alcoholic fatty liver disease-associated gene PNPLA3/adiponutrin in mouse liver and HepG2 human liver cells

Metabolism: Clinical and Experimental

Volumn 63, Issue 10, 2014, Pages 1352-1362

  Hao, Lei ^a   Ito, Kyoko ^a   Huang, Kuan Hsun ^a   Sae Tan, Sudathip ^a   Lambert, Joshua D ^a   Ross, A Catharine ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Glucose; Lipid emulsion; Nonalcoholic fatty liver disease; Patatin like phospholipase domain containing 3

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ADIPONUTRIN; GLUCAGON; GLUCOSE; INSULIN; LIPID EMULSION; LIPOPROTEIN; MESSENGER RNA; OLEIC ACID; STEROL REGULATORY ELEMENT BINDING PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; UNCLASSIFIED DRUG; UNSATURATED FATTY ACID; LIPID; MEMBRANE PROTEIN;

ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARBOHYDRATE DIET; CONTROLLED STUDY; HEPG2 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIPID DIET; LIPID LIVER LEVEL; LIPID METABOLISM; LIPID STORAGE; LOW FAT DIET; MALE; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; FATTY LIVER; GENE EXPRESSION; GENETICS; LIPOGENESIS; LIVER; LIVER CELL; METABOLISM; METHODOLOGY; PATATIN-LIKE PHOSPHOLIPASE DOMAIN CONTAINING 3; TUMOR CELL LINE;

GLUCOSE; LIPID EMULSION; NONALCOHOLIC FATTY LIVER DISEASE; PATATIN-LIKE PHOSPHOLIPASE DOMAIN CONTAINING 3;

ANIMALS; CELL LINE, TUMOR; DIET, HIGH-FAT; DIETARY CARBOHYDRATES; FATTY LIVER; GENE EXPRESSION; GLUCAGON; GLUCOSE; HEP G2 CELLS; HEPATOCYTES; HUMANS; INSULIN; LIPID METABOLISM; LIPIDS; LIPOGENESIS; LIVER; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL;

EID: 84908250676     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2014.06.016     Document Type: Article

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