Transient suppression of TGFβ receptor signaling facilitates human islet transplantation

Endocrinology

Volumn 157, Issue 4, 2016, Pages 1348-1356

  Xiao, Xiangwei ^a   Fischbach, Shane ^a   Song, Zewen ^a,b   Gaffar, Iljana ^a   Zimmerman, Ray ^a   Wiersch, John ^a   Prasadan, Krishna ^a   Shiota, Chiyo ^a   Guo, Ping ^a   Ramachandran, Sabarinathan ^c   Witkowski, Piotr ^c   Gittes, George K ^a  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^b THE THIRD XIANGYA HOSPITAL OF CENTRAL SOUTH UNIVERSITY   (China)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; BECLIN 1; C PEPTIDE; CASPASE 9; CYCLIN D1; CYCLIN D2; CYCLIN DEPENDENT KINASE 4; CYTOCHROME C; GLUCOSE; INSULIN; PROTEIN P27; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; 1,3 DIOXOLANE DERIVATIVE; 4-(5-BENZO(1,3)DIOXOL-5-YL-4-PYRIDIN-2-YL-1H-IMIDAZOL-2-YL)BENZAMIDE; BENZAMIDE DERIVATIVE; GLUCOSE BLOOD LEVEL; PROTEIN SERINE THREONINE KINASE; TGF-BETA TYPE I RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BLOOD GLUCOSE MONITORING; CAPILLARY DENSITY; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; DIABETES MELLITUS; DRUG MECHANISM; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HUMAN; HUMAN CELL; INSULIN BLOOD LEVEL; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SCID MOUSE; SIGNAL TRANSDUCTION; TREATMENT OUTCOME; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; CELL CULTURE; CONFOCAL MICROSCOPY; DRUG EFFECTS; METABOLISM; NONOBESE DIABETIC MOUSE; PANCREAS ISLET; PHYSIOLOGY; PROCEDURES; SECRETION (PROCESS); WESTERN BLOTTING; XENOGRAFT;

ANIMALS; BENZAMIDES; BLOOD GLUCOSE; BLOTTING, WESTERN; C-PEPTIDE; CELL PROLIFERATION; CELLS, CULTURED; DIOXOLES; FEMALE; HUMANS; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; MICE, INBRED NOD; MICE, SCID; MICROSCOPY, CONFOCAL; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; TRANSPLANTATION, HETEROLOGOUS;

EID: 84964412501     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2015-1986     Document Type: Article

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