Differential synthesis and action of TGFβ superfamily ligands in mouse and rat islets

Islets

Volumn 3, Issue 6, 2011, Pages 367-375

  Brown, Melissa L ^a   Kimura, Fuminori ^a   Bonomi, Lara M ^a   Ungerleider, Nathan A ^a   Schneyer, Alan L ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Activin; Follistatin; Insulin; Islet; Myostatin; TGF

Indexed keywords

ACTIVIN A; FOLLISTATIN; MYELOPID; MYOSTATIN; OSTEOGENIC PROTEIN 1; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ISOLATION; CELLULAR DISTRIBUTION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; GLUCAGON RELEASE; GLUCOSE STIMULATED INSULIN SECRETION; IMMUNOHISTOCHEMISTRY; INSULIN RELEASE; MALE; MOUSE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET CELL HYPERPLASIA; PROTEIN EXPRESSION; RAT;

ACTIVINS; ANIMALS; GLUCOSE; IMMUNOHISTOCHEMISTRY; INSULIN; ISLETS OF LANGERHANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOSTATIN; PROTEINS; RATS; RATS, INBRED LEW; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPECIES SPECIFICITY; TRANSFORMING GROWTH FACTOR BETA;

EID: 80455135050     PISSN: 19382014     EISSN: 19382022     Source Type: Journal    
DOI: 10.4161/isl.3.6.18013     Document Type: Article

References (34)

1. Huang ES, Basu A, O'Grady M, Capretta JC. Projecting the future diabetes population size and related costs for the US Diabetes Care 2009; 32:2225-9; PMID:19940225; DOI:10.2337/dc09-0459.
2. Kahn SE, Hull RL, Utzschneider KM. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 2006; 444:840-6; PMID:17167471; DOI:10.1038/nature05482.
3. Bonner-Weir S, Weir GC. New sources of pancreatic beta-cells. Nat Biotechnol 2005; 23:857-61; PMID:16003374; DOI:10.1038/nbt1115.
4. Massagué J. TGFbeta in cancer. Cell 2008; 134:215-30; PMID:18662538; DOI:10.1016/j.cell.2008.07.001.
5. Brown ML, Schneyer A. Emerging roles for TGFβ family in β-cell homeostasis. Trends Endocrinol Metab 2010; 21:441-8; PMID:20382030; DOI:10.1016/j.tem.2010.02.008.
6. Oliver-Krasinski JM, Stoffers DA. On the origin of the {beta} cell. Genes Dev 2008; 22:1998-2021; PMID:18676806; DOI:10.1101/gad.1670808.
7. Goulley J, Dahl U, Baeza N, Mishina Y, Edlund H. BMP4-BMPR1A signaling in beta cells is required for and augments glucose-stimulated insulin secretion. Cell Metab 2007; 5:207-19; PMID:17339028; DOI:10.1016/j.cmet.2007.01.009.
8. Yamaoka T, Idehara C, Yano M, Matsushita T, Yamada T, Ii S, et al. Hypoplasia of pancreatic islets in transgenic mice expressing activin receptor mutants. J Clin Invest 1998; 102:294-301; PMID:9664070; DOI:10.1172/JCI2769.
9. Shiozaki S, Tajima T, Zhang YQ, Furukawa M, Nakazato Y, Kojima I. Impaired differentiation of endocrine and exocrine cells of the pancreas in transgenic mouse expressing the truncated type II activin receptor. Biochim Biophys Acta 1999; 1450:1-11; PMID:10231550; DOI:10.1016/S0167-4889(99)00022-1.
10. Kim SK, Hebrok M, Li E, Oh SP, Schrewe H, Harmon EB, et al. Activin receptor patterning of foregut organogenesis. Genes Dev 2000; 14:1866-71; PMID:10921901.
11. Smart NG, Apelqvist AA, Gu X, Harmon EB, Topper JN, MacDonald RJ, et al. Conditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitus. PLoS Biol 2006; 4:39; PMID:16435884; DOI:10.1371/journal.pbio.0040039.
12. Verspohl EJ, Ammon HP, Wahl MA. Activin A: its effects on rat pancreatic islets and the mechanism of action involved. Life Sci 1993; 53:1069-78; PMID:8366769; DOI:10.1016/0024-3205(93)90260-A.
13. Florio P, Luisi S, Marchetti P, Lupi R, Cobellis L, Falaschi C, et al. Activin A stimulates insulin secretion in cultured human pancreatic islets. J Endocrinol Invest 2000; 23:231-4; PMID:10853708.
14. Brun T, Franklin I, St-Onge L, Biason-Lauber A, Schoenle EJ, Wollheim CB, et al. The diabetes-linked transcription factor PAX4 promotes {beta}-cell proliferation and survival in rat and human islets. J Cell Biol 2004; 167:1123-35; PMID:15596543; DOI:10.1083/jcb.200405148.
15. Totsuka Y, Tabuchi M, Kojima I, Eto Y, Shibai H, Ogata E. Stimulation of insulin secretion by transforming growth factor-beta. Biochem Biophys Res Commun 1989; 158:1060-5; PMID:2645864; DOI:10.1016/0006-291X(89)92829-5.
16. Sjöholm A, Hellerstrom C. TGF-beta stimulates insulin secretion and blocks mitogenic response of pancreatic beta-cells to glucose. Am J Physiol 1991; 260:1046-51; PMID:2035613.
17. Lin HM, Lee JH, Yadav H, Kamaraju AK, Liu E, Zhigang D, et al. Transforming growth factor-β/smad3 signaling regulates insulin gene transcription and pancreatic islet β-cell function. J Biol Chem 2009; 284:12246-57; PMID:19265200; DOI:10.1074/jbc.M805379200.
18. Schneyer AL, Sidis Y, Gulati A, Sun JL, Keutmann H, Krasney PA. Differential antagonism of activin, myostatin and growth and differentiation factor 11 by wild-type and mutant follistatin. Endocrinology 2008; 149:4589-95; PMID:18535106; DOI:10.1210/en.2008-0259.
19. Sidis Y, Mukherjee A, Keutmann H, Sun JL, Keutmann H, Krasney PA, et al. Biological activity of follistatin isoforms and follistatin-like-3 is dependent on differential cell surface binding and specificity for activin, myostatin and bone morphogenetic proteins. Endocrinology 2006; 147:3586-97; PMID:16627583; DOI:10.1210/en.2006-0089.
20. Mukherjee A, Sidis Y, Mahan A, Raher MJ, Xia Y, Rosen ED, et al. FSTL3 deletion reveals roles for TGF-beta family ligands in glucose and fat homeostasis in adults. Proc Natl Acad Sci USA 2007; 104:1348-53; PMID:17229845; DOI:10.1073/pnas.0607966104.
21. + islet progenitor cell number and promotes beta-cell differentiation in pancreas development. Development 2004; 131:6163-74; PMID:15548585; DOI:10.1242/dev.01535.
22. McPherron AC, Lee SJ. Suppression of body fat accumulation in myostatin-deficient mice. J Clin Invest 2002; 109:595-601; PMID:11877467.
23. McPherron AC, Lawler AM, Lee SJ. Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature 1997; 387:83-90; PMID:9139826; DOI:10.1038/387083a0.
24. Guo T, Jou W, Chanturiya T, Portas J, Gavrilova O, McPherron AC. Myostatin inhibition in muscle, but not adipose tissue, decreases fat mass and improves insulin sensitivity. PLoS One 2009; 4:e4937; PMID:19295913; DOI:10.1371/journal.pone.0004937.
25. Weiss J, Crowley WF Jr, Halvorson LM, Jameson JL. Perifusion of rat pituitary cells with gonadotropin-releasing hormone, activin and inhibin reveals distinct effects on gonadotropin gene expression and secretion. Endocrinology 1993; 132:2307-11; PMID:8504735; DOI:10.1210/en.132.6.2307.
26. Ogawa K, Abe K, Kurosawa N, Kurohmaru M, Sugino H, Takahashi M, et al. Expression of alpha, betaA and betaB subunits of inhibin or activin and follistatin in rat pancreatic islets. FEBS Lett 1993; 319:217-20; PMID:8458412; DOI:10.1016/0014-5793(93)80549-A.
27. Szabat M, Johnson JD, Piret JM. Reciprocal modulation of adult beta cell maturity by activin A and follistatin. Diabetologia 2010; 53:1680-9; PMID:20440469; DOI:10.1007/s00125-010-1758-0.
28. Yasuda H, Inoue K, Shibata H, et al. Existence of activin-A in A- and D-cells of rat pancreatic islet. Endocrinology 1993; 133:624-30; PMID:8344202; DOI:10.1210/en.133.2.624.
29. Mamin A, Philippe J, Activin A. Decreases glucagon and arx gene expression in {alpha}-cell lines. Mol Endocrinol 2007; 21:259-73; PMID:16988001; DOI:10.1210/me.2005-0530.
30. Park MK, Han C, Lee KH, Hong SH, Kim HS, Lee YJ, et al. Effects of activin A on pancreatic ductal cells in streptozotocin-induced diabetic rats. Transplantation 2007; 83:925-30; PMID:17460564; DOI:10.1097/01.tp.0000259978. 62139.9d.
31. Zhang YQ, Cleary MM, Si Y, Liu G, Eto Y, Kritzik M, et al. Inhibition of activin signaling induces pancreatic epithelial cell expansion and diminishes terminal differentiation of pancreatic beta-cells. Diabetes 2004; 53:2024-33. (Pubitemid 38970751)
32. Lalani R, Bhasin S, Byhower F, Tarnuzzer R, Grant M, Shen R, et al. Myostatin and insulin-like growth factor-I and -II expression in the muscle of rats exposed to the microgravity environment of the NeuroLab space shuttle flight. J Endocr 2000; 167:417-28; PMID:11115768; DOI:10.1677/joe.0.1670417.
33. Matsakas A, Bozzo C, Cacciani N, Caliaro F, Reggiani C, Mascarello F, et al. Effect of swimming on myostatin expression in white and red gastrocnemius muscle and in cardiac muscle of rats. Exp Physiol 2006; 91:983-94; PMID:16873457; DOI:10.1113/expphysiol.2006.033571.
34. Kimura F, Sidis Y, Bonomi L, Xia Y, Schneyer A. The follistatin-288 isoform alone is sufficient for survival but not for normal fertility in mice. Endocrinology 2010; 151:1310-9; PMID:20032047; DOI:10.1210/en.2009-1176.