Pancreatic beta cells in very old mice retain capacity for compensatory proliferation

Journal of Biological Chemistry

Volumn 287, Issue 33, 2012, Pages 27407-27414

  Stolovich Rain, Miri ^a   Hija, Ayat ^a   Grimsby, Joseph ^b   Glaser, Benjamin ^c   Dor, Yuval ^a  

^a HEBREW UNIVERSITY   (Israel)

^b Hoffman La Roche Department of Metabolic Diseases   (United States)

^c HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

BASAL CONDITIONS; BETA CELL; DIPHTHERIA TOXIN; GLUCOKINASE; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; HIGH-FAT DIET; MITOGENIC; OLD AGE; PANCREATIC BETA CELLS; PARTIAL PANCREATECTOMY; SMALL MOLECULES; STREPTOZOTOCIN INJECTIONS; TRANSGENIC MICE; TRANSIENT EXPRESSION;

CYTOLOGY; GLUCOSE; MAMMALS; MEDICAL PROBLEMS;

CELLS;

DIPHTHERIA TOXIN; DOXYCYCLINE; ENZYME ACTIVATOR; GLUCOKINASE ACTIVATOR; UNCLASSIFIED DRUG;

AGE; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIVISION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; GLYCOLYSIS; MOUSE; NONHUMAN; PANCREAS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; TRANSGENIC MOUSE;

AGING; ANIMALS; CELL PROLIFERATION; DIPHTHERIA TOXIN; ENZYME ACTIVATORS; GENE EXPRESSION; GLUCOKINASE; GLUCOSE; GLUCOSE TOLERANCE TEST; INSULIN-SECRETING CELLS; MICE; MICE, TRANSGENIC; TRANSGENES;

EID: 84865029204     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.350736     Document Type: Article

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