Design and evaluation of lipoprotein resembling curcumin-encapsulated protein-free nanostructured lipid carrier for brain targeting

International Journal of Pharmaceutics

Volumn 506, Issue 1-2, 2016, Pages 46-56

  Meng, Fanfei ^a   Asghar, Sajid ^a,b   Xu, Yurui ^a   Wang, Jianping ^a   Jin, Xin ^a   Wang, Zhilin ^a   Wang, Jing ^c   Ping, Qineng ^a   Zhou, Jianping ^a   Xiao, Yanyu ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b GOVERNMENT COLLEGE UNIVERSITY   (Pakistan)

^c LIAOCHENG PEOPLE'S HOSPITAL   (China)

Author keywords

Brain targeting; Curcumin; Drug delivery; Lipoprotein; Protein free nanostructured lipid carrier

Indexed keywords

CURCUMIN; LIPOPROTEIN; NANOCARRIER; NANOMATERIAL; NANOSTRUCTURED LIPID CARRIER; UNCLASSIFIED DRUG; DRUG CARRIER; LIPID; NANOPARTICLE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOCOMPATIBILITY; BLOOD BRAIN BARRIER; BRAIN; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACCUMULATION; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG PENETRATION; DRUG RELEASE; DRUG SAFETY; FLUORESCENCE; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MOUSE; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PLASMA; PRIORITY JOURNAL; RAT; ZETA POTENTIAL; ANIMAL; CELL LINE; CHEMISTRY; DRUG EFFECTS; INSTITUTE FOR CANCER RESEARCH MOUSE; MEDICINAL CHEMISTRY; PROCEDURES; SPRAGUE DAWLEY RAT;

ANIMALS; BRAIN; CELL LINE; CHEMISTRY, PHARMACEUTICAL; CURCUMIN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; LIPIDS; LIPOPROTEINS; MICE; MICE, INBRED ICR; NANOPARTICLES; NANOSTRUCTURES; PARTICLE SIZE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84964336792     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2016.04.033     Document Type: Article

References (55)

1. S. Acharya, F. Dilnawaz, and S.K. Sahoo Targeted epidermal growth factor receptor nanoparticle bioconjugates for breast cancer therapy Biomaterials 30 2009 5737 5750
2. S. Asghar, J.M.M. Salmani, W. Hassan, Y. Xie, F. Meng, Z. Su, M. Sun, Y. Xiao, and Q. Ping A facile approach for crosslinker free nano self assembly of protein for anti-tumor drug delivery: factors' optimization, characterization and in vitro evaluation Eur. J. Pharm. Sci. 63 2014 53 62
3. D. Chen, and K.H. Lee Biodistribution of calcitonin encapsulated in liposomes in mice with particular reference to the central nervous system Biochim. Biophys. Acta 1158 1993 244 250
4. F.Z. Dahmani, H. Yang, J. Zhou, J. Yao, T. Zhang, and Q. Zhang Enhanced oral bioavailability of paclitaxel in pluronic/LHR mixed polymeric micelles: preparation, in vitro and in vivo evaluation Eur. J. Pharm. Sci. 47 2012 179 189
5. S. Das, and A. Chaudhury Recent advances in lipid nanoparticle formulations with solid matrix for oral drug delivery AAPS PharmSciTech 12 2011 62 76
6. S. Das, W.K. Ng, and R.B. Tan Are nanostructured lipid carriers (NLCs) better than solid lipid nanoparticles (SLNs): development, characterizations and comparative evaluations of clotrimazole-loaded SLNs and NLCs? Eur. J. Pharm. Sci. 47 2012 139 151
7. A.O. Elzoghby, W.M. Samy, and N.A. Elgindy Albumin-based nanoparticles as potential controlled release drug delivery systems J. Control. Release: Off. J. Control. Release Soc. 157 2012 168 182
8. A. Fabregas, N. Sanchez-Hernandez, J.R. Tico, E. Garcia-Montoya, P. Perez-Lozano, J.M. Sune-Negre, C. Hernandez-Munain, C. Sune, and M. Minarro A new optimized formulation of cationic solid lipid nanoparticles intended for gene delivery: development, characterization and DNA binding efficiency of TCERG1 expression plasmid Int. J. Pharm. 473 2014 270 279
9. J.Y. Fang, C.L. Fang, C.H. Liu, and Y.H. Su Lipid nanoparticles as vehicles for topical psoralen delivery: solid lipid nanoparticles (SLN) versus nanostructured lipid carriers (NLC) Eur. J. Pharm. Biopharm. 70 2008 633 640
10. R. Gabathuler Approaches to transport therapeutic drugs across the blood-brain barrier to treat brain diseases Neurobiol. Dis. 37 2010 48 57
11. K. Gao, and X. Jiang Influence of particle size on transport of methotrexate across blood brain barrier by polysorbate 80-coated polybutylcyanoacrylate nanoparticles Int. J. Pharm. 310 2006 213 219
12. L. Gastaldi, L. Battaglia, E. Peira, D. Chirio, E. Muntoni, I. Solazzi, M. Gallarate, and F. Dosio Solid lipid nanoparticles as vehicles of drugs to the brain: current state of the art Eur. J. Pharm. Biopharm. 87 2014 433 444
13. S. Gelperina, O. Maksimenko, A. Khalansky, L. Vanchugova, E. Shipulo, K. Abbasova, R. Berdiev, S. Wohlfart, N. Chepurnova, and J. Kreuter Drug delivery to the brain using surfactant-coated poly(lactide-co-glycolide) nanoparticles: influence of the formulation parameters Eur. J. Pharm. Biopharm. 74 2010 157 163
14. T. Hekmatara, S. Gelperina, V. Vogel, S.R. Yang, and J. Kreuter Encapsulation of water-insoluble drugs in poly(butyl cyanoacrylate) nanoparticles J. Nanosci. Nanotechnol. 9 2009 5091 5098
15. D.B. Huntosova, D. Petrovajova, P. Kasak, Z. Nadova, D. Jancura, F. Sureau, and P. Miskovsky Development of a new LDL-based transport system for hydrophobic/amphiphilic drug delivery to cancer cells Int. J. Pharm. 436 2012 463 471
16. J. Huwyler, D. Wu, and W.M. Pardridge Brain drug delivery of small molecules using immunoliposomes Proc. Natl. Acad. Sci. U. S. A. 93 1996 14164 14169
17. K. Jores, W. Mehnert, M. Drechsler, H. Bunjes, C. Johann, and K. Mader Investigations on the structure of solid lipid nanoparticles (SLN) and oil-loaded solid lipid nanoparticles by photon correlation spectroscopy, field-flow fractionation and transmission electron microscopy J. Control. Release 95 2004 217 227
18. J. Kreuter, D. Shamenkov, V. Petrov, P. Ramge, K. Cychutek, C. Koch-Brandt, and R. Alyautdin Apolipoprotein-mediated transport of nanoparticle-bound drugs across the blood-brain barrier J. Drug Target. 10 2002 317 325
19. J. Kreuter, T. Hekmatara, S. Dreis, T. Vogel, S. Gelperina, and K. Langer Covalent attachment of apolipoprotein A-I and apolipoprotein B-100 to albumin nanoparticles enables drug transport into the brain J. Control. Release 118 2007 54 58
20. J. Kreuter Nanoparticulate systems for brain delivery of drugs Adv. Drug Deliv. Rev. 47 2001 65 81
21. Y.-C. Kuo, and C.-Y. Shih-Huang Solid lipid nanoparticles with surface antibody for targeting the brain and inhibiting lymphatic phagocytosis J. Taiwan Inst. Chem. Eng. 45 2014 1154 1163
22. P.R. Lockman, J.M. Koziara, R.J. Mumper, and D.D. Allen Nanoparticle surface charges alter blood-brain barrier integrity and permeability J. Drug Target. 12 2004 635 641
23. Y. Luo, D. Chen, L. Ren, X. Zhao, and J. Qin Solid lipid nanoparticles for enhancing vinpocetine's oral bioavailability J. Control. Release 114 2006 53 59
24. S. Martins, I. Tho, I. Reimold, G. Fricker, E. Souto, D. Ferreira, and M. Brandl Brain delivery of camptothecin by means of solid lipid nanoparticles: formulation design, in vitro and in vivo studies Int. J. Pharm. 439 2012 49 62
25. S.M. Martins, B. Sarmento, C. Nunes, M. Lucio, S. Reis, and D.C. Ferreira Brain targeting effect of camptothecin-loaded solid lipid nanoparticles in rat after intravenous administration Eur. J. Pharm. Biopharm. 85 2013 488 502
26. M. Masquelier, B. Lundberg, C. Peterson, and S. Vitols Cytotoxic effect of a lipophilic alkylating agent after incorporation into low density lipoprotein or emulsions: studies in human leukemic cells Leuk. Res. 30 2006 136 144
27. F. Meng, S. Asghar, S. Gao, Z. Su, J. Song, M. Huo, W. Meng, Q. Ping, and Y. Xiao A novel LDL-mimic nanocarrier for the targeted delivery of curcumin into the brain to treat Alzheimer's disease Colloids Surf., B 134 2015 88 97
28. C. Mohanty, and S.K. Sahoo The in vitro stability and in vivo pharmacokinetics of curcumin prepared as an aqueous nanoparticulate formulation Biomaterials 31 2010 6597 6611
29. V. Papadopoulou, K. Kosmidis, M. Vlachou, and P. Macheras On the use of the Weibull function for the discernment of drug release mechanisms Int. J. Pharm. 309 2006 44 50
30. W.M. Pardridge Blood-brain barrier delivery Drug Discov. Today 12 2007 54 61
31. P. Costa, and J.M. Sousa Lobo Modeling and comparison of dissolution profiles Eur. J. Pharm. Sci. 13 2001 123 133
32. B. Petri, A. Bootz, A. Khalansky, T. Hekmatara, R. Muller, R. Uhl, J. Kreuter, and S. Gelperina Chemotherapy of brain tumour using doxorubicin bound to surfactant-coated poly(butyl cyanoacrylate) nanoparticles: revisiting the role of surfactants J. Control. Release 117 2007 51 58
33. R. Prassl, and P. Laggner Molecular structure of low density lipoprotein: current status and future challenges Eur. Biophys. J 38 2009 145 158
34. M. Ricci, P. Blasi, S. Giovagnoli, and C. Rossi Delivering drugs to the central nervous system: a medicinal chemistry or a pharmaceutical technology issue? Curr. Med. Chem. 13 2006 1757 1775
35. R. Qiao, Q. Jia, S. Hüwel, R. Xia, T. Liu, F. Gao, H.J. Galla, and M. Gao Receptor-Mediated delivery of magnetic nanoparticles across the blood-brain barrier ACS Nano 6 2012 3304 3310
36. S.N.H. Shah, S. Asghar, M.A. Choudhry, M.S.H. Akash, and S. Rehman N. u. Baksh Formulation and evaluation of natural gum-based sustained release matrix tablets of flurbiprofen using response surface methodology Drug Dev. Ind. Pharm. 35 2009 1470 1478
37. S.J. Lim, and C.K. Kim Formulation parameters determining the physicochemical characteristics of solid lipid nanoparticles loaded with all-trans retinoic acid Int. J. Pharm. 243 2002 135 146
38. Z. Su, J. Niu, Y. Xiao, Q. Ping, M. Sun, A. Huang, W. You, X. Sang, and D. Yuan Effect of octreotide-polyethylene glycol(100) monostearate modification on the pharmacokinetics and cellular uptake of nanostructured lipid carrier loaded with hydroxycamptothecine Mol. Pharm. 8 2011 1641 1651
39. Z. Su, Y. Shi, Y. Xiao, M. Sun, Q. Ping, L. Zong, S. Li, J. Niu, A. Huang, W. You, Y. Chen, X. Chen, J. Fei, and J. Tian Effect of octreotide surface density on receptor-mediated endocytosis in vitro and anticancer efficacy of modified nanocarrier in vivo after optimization Int. J. Pharm. 447 2013 281 292
40. Z. Su, L. Xing, Y. Chen, Y. Xu, F. Yang, C. Zhang, Q. Ping, and Y. Xiao Lactoferrin-modified poly(ethylene glycol)-grafted BSA nanoparticles as a dual-targeting carrier for treating brain gliomas Mol. Pharm. 11 2014 1823 1834
41. R.K. Subedi, K.W. Kang, and H.K. Choi Preparation and characterization of solid lipid nanoparticles loaded with doxorubicin Eur. J. Pharm. Sci. 37 2009 508 513
42. W. Sun, C. Xie, H. Wang, and Y. Hu Specific role of polysorbate 80 coating on the targeting of nanoparticles to the brain Biomaterials 25 2004 3065 3071
43. J. Sun, C. Bi, H.M. Chan, S. Sun, Q. Zhang, and Y. Zheng Curcumin-loaded solid lipid nanoparticles have prolonged in vitro antitumour activity, cellular uptake and improved in vivo bioavailability Colloids Surf., B 111 2013 367 375
44. M.J. Tsai, P.C. Wu, Y.B. Huang, J.S. Chang, C.L. Lin, Y.H. Tsai, and J.Y. Fang Baicalein loaded in tocol nanostructured lipid carriers (tocol NLCs) for enhanced stability and brain targeting Int. J. Pharm. 423 2012 461 470
45. C. Vauthier, D. Labarre, and G. Ponchel Design aspects of poly(alkylcyanoacrylate) nanoparticles for drug delivery J. Drug Target 15 2007 641
46. C.X. Wang, L.S. Huang, L.B. Hou, L. Jiang, Z.T. Yan, Y.L. Wang, and Z.L. Chen Antitumor effects of polysorbate-80 coated gemcitabine polybutylcyanoacrylate nanoparticles in vitro and its pharmacodynamics in vivo on C6 glioma cells of a brain tumor model Brain Res. 1261 2009 91 99
47. S. Wang, T. Chen, R. Chen, Y. Hu, M. Chen, and Y. Wang Emodin loaded solid lipid nanoparticles: preparation, characterization and antitumor activity studies Int. J. Pharm. 430 2012 238 246
48. S. Wohlfart, S. Gelperina, and J. Kreuter Transport of drugs across the blood-brain barrier by nanoparticles J. Control. Release 161 2012 264 273
49. Y. Xiao, X. Chen, L. Yang, X. Zhu, L. Zou, F. Meng, and Q. Ping Preparation and oral bioavailability study of curcuminoid-loaded microemulsion J. Agric. Food Chem. 61 2013 3654 3660
50. L. Yang, S. Gao, S. Asghar, G. Liu, J. Song, X. Wang, Q. Ping, C. Zhang, and Y. Xiao Hyaluronic acid/chitosan nanoparticles for delivery of curcuminoid and its in vitro evaluation in glioma cells Int. J. Biol. Macromol. 72 2015 1391 1401
51. W. Zhang, J. Liu, S. Li, M. Chen, and H. Liu Preparation and evaluation of stealth Tashinone IIA-loaded solid lipid nanoparticles: Influence of Poloxamer 188 coating on phagocytic uptake J. Microencapsul. 25 2008 203 209
52. W.L. Zhang, X. Gu, H. Bai, R.H. Yang, C.D. Dong, and J.P. Liu Nanostructured lipid carriers constituted from high-density lipoprotein components for delivery of a lipophilic cardiovascular drug Int. J. Pharm. 391 2010 313 321
53. Y. Zhang, M. Huo, J. Zhou, A. Zou, W. Li, C. Yao, and S. Xie DDSolver: an add-in program for modeling and comparison of drug dissolution profiles AAPS J. 12 2010 263 271
54. C. Zhao, Y. Liu, T. Fan, D. Zhou, Y. Yang, Y. Jin, Z. Zhang, and Y. Huang A novel strategy for encapsulating poorly soluble drug into nanostructured lipid carriers for intravenous administration Pharm. Dev. Technol. 17 2012 443 456
55. Q.L. Zhu, Y. Zhou, M. Guan, X.F. Zhou, S.D. Yang, Y. Liu, W.L. Chen, C.G. Zhang, Z.Q. Yuan, C. Liu, A.J. Zhu, and X.N. Zhang Low-density lipoprotein-coupled N-succinyl chitosan nanoparticles co-delivering siRNA and doxorubicin for hepatocyte-targeted therapy Biomaterials 35 2014 5965 5976