Emodin loaded solid lipid nanoparticles: Preparation, characterization and antitumor activity studies

International Journal of Pharmaceutics

Volumn 430, Issue 1-2, 2012, Pages 238-246

  Wang, Shengpeng ^a   Chen, Tongkai ^b   Chen, Ruie ^a   Hu, Yangyang ^a   Chen, Meiwan ^a   Wang, Yitao ^a  

^a University of Macau   (Macao)

^b Guangzhou Institute of Pharmaceutical Industry   (China)

Author keywords

Antitumor; Emodin; High pressure homogenization; Solid lipid nanoparticles

Indexed keywords

EMODIN; POLOXAMER; POLYSORBATE 80; SOLID LIPID NANOPARTICLE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST EPITHELIUM; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL STRAIN MCF 7; CHEMICAL MODIFICATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG MECHANISM; DRUG QUALITY; DRUG SOLUBILITY; DRUG STABILITY; DRUG STORAGE; FLOW CYTOMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE HOMOGENIZATION; HUMAN; HUMAN CELL; IC 50; NANOPHARMACEUTICS; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; STAINING; SUSTAINED DRUG RELEASE; TIME; ZETA POTENTIAL;

ADMINISTRATION, ORAL; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BREAST NEOPLASMS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CHEMISTRY, PHARMACEUTICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; DRUG COMPOUNDING; DRUG STABILITY; EMODIN; FEMALE; FLOW CYTOMETRY; HUMANS; INHIBITORY CONCENTRATION 50; KINETICS; LIPIDS; NANOPARTICLES; NANOTECHNOLOGY; PARTICLE SIZE; PRESSURE; SOLUBILITY; STAINING AND LABELING; SURFACE-ACTIVE AGENTS; TECHNOLOGY, PHARMACEUTICAL;

EID: 84860727944     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.03.027     Document Type: Article

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