Mitochondria-targeted esculetin alleviates mitochondrial dysfunction by AMPK-mediated nitric oxide and SIRT3 regulation in endothelial cells: Potential implications in atherosclerosis

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Karnewar, Santosh ^a,b   Vasamsetti, Sathish Babu ^a,b   Gopoju, Raja ^a,b   Kanugula, Anantha Koteswararao ^a   Ganji, Sai Krishna ^a   Prabhakar, Sripadi ^a   Rangaraj, Nandini ^c   Tupperwar, Nitin ^c   Kumar, Jerald Mahesh ^c   Kotamraju, Srigiridhar ^a,b  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^b ACADEMY OF SCIENTIFIC AND INNOVATIVE RESEARCH   (India)

^c CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN II; ANTIOXIDANT; APOLIPOPROTEIN E; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ESCULETIN; HYDROGEN PEROXIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; SIRTUIN 3; SMALL INTERFERING RNA; UMBELLIFERONE DERIVATIVE;

ANIMAL; ANTAGONISTS AND INHIBITORS; AORTA; APOPTOSIS; ATHEROSCLEROSIS; CELL CULTURE; CELL SURVIVAL; CHEMISTRY; CONFOCAL MICROSCOPY; CYTOLOGY; DEFICIENCY; DRUG EFFECTS; ENDOTHELIUM CELL; GENETICS; HUMAN; KNOCKOUT MOUSE; MALE; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PATHOLOGY; PHOSPHORYLATION; RNA INTERFERENCE;

AMP-ACTIVATED PROTEIN KINASES; ANGIOTENSIN II; ANIMALS; ANTIOXIDANTS; AORTA; APOLIPOPROTEINS E; APOPTOSIS; ATHEROSCLEROSIS; CELL SURVIVAL; CELLS, CULTURED; ENDOTHELIAL CELLS; HUMANS; HYDROGEN PEROXIDE; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; MITOCHONDRIA; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PHOSPHORYLATION; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIRTUIN 3; UMBELLIFERONES;

EID: 84964322461     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep24108     Document Type: Article

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