Mitochondrial-targeted curcuminoids: A strategy to enhance bioavailability and anticancer efficacy of curcumin

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Reddy, Cheruku Apoorva ^a   Somepalli, Venkateswarlu ^b   Golakoti, Trimurtulu ^b   Kanugula, Anantha KoteswaraRao ^c   Karnewar, Santosh ^c   Rajendiran, Karthikraj ^c   Vasagiri, Nagarjuna ^a   Prabhakar, Sripadi ^c   Kuppusamy, Periannan ^d   Kotamraju, Srigiridhar ^c   Kutala, Vijay Kumar ^a  

^a NIZAM'S INSTITUTE OF MEDICAL SCIENCES   (India)

^b Unit I   (India)

^c INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^d DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 8; CURCUMIN; METHYLTRIPHENYLPHOSPHONIUM; MITOCURCUMINOID 1; MITOCURCUMINOID 2; MITOCURCUMINOID 3; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BNIP3; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; STAT3 PROTEIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; BNIP3 PROTEIN, HUMAN; MEMBRANE PROTEIN; ONCOPROTEIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL STRAIN MCF 7; CELL TRANSPORT; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG UPTAKE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HELA CELL; HUMAN; HUMAN CELL; IC 50; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UPREGULATION; BIOAVAILABILITY; CELL CYCLE CHECKPOINT; CHEMISTRY; CYTOSOL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; METABOLISM; SIGNAL TRANSDUCTION; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BIOLOGICAL AVAILABILITY; BIOLOGICAL TRANSPORT; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CURCUMIN; CYTOSOL; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MAP KINASE SIGNALING SYSTEM; MEMBRANE POTENTIAL, MITOCHONDRIAL; MEMBRANE PROTEINS; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; STAT3 TRANSCRIPTION FACTOR;

EID: 84898007849     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0089351     Document Type: Article

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