Transferrin receptor-dependent iron uptake is responsible for doxorubicin-mediated apoptosis in endothelial cells. Role of oxidant-induced iron signaling in apoptosis

Journal of Biological Chemistry

Volumn 277, Issue 19, 2002, Pages 17179-17187

  Kotamraju, Srigiridhar ^a,b   Chitambar, Christopher R ^a,b   Kalivendi, Shasi V ^a,b   Joseph, Joy ^a,b   Kalyanaraman, B ^a,b  

^a FREE RADICAL RESEARCH CENTER   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CELLS; DRUG PRODUCTS; IRON; TUMORS;

APOPTOSIS;

PROTEINS;

CHELATING AGENT; DOXORUBICIN; FLUORESCEIN DERIVATIVE; IRON; IRON REGULATORY FACTOR; OXIDIZING AGENT; REACTIVE OXYGEN METABOLITE; TRANSFERRIN RECEPTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CARDIOTOXICITY; CONTROLLED STUDY; ENDOTHELIUM CELL; FLUORESCENCE; IRON TRANSPORT; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ACONITATE HYDRATASE; ANIMALS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; APOPTOSIS; CASPASE 3; CASPASES; CATTLE; CELL LINE; CHELATING AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; ENDOTHELIUM; IRON; MODELS, BIOLOGICAL; OXIDATION-REDUCTION; OXIDATIVE STRESS; OXYGEN; PHENANTHRIDINES; REACTIVE OXYGEN SPECIES; RECEPTORS, TRANSFERRIN; SIGNAL TRANSDUCTION; TIME FACTORS;

ANIMALIA; BOVINAE; LETHRINIDAE;

EID: 0037053406     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M111604200     Document Type: Article

References (72)