Characterization of Intersubunit Communication in the Virginiamycin trans-Acyl Transferase Polyketide Synthase

Journal of the American Chemical Society

Volumn 138, Issue 12, 2016, Pages 4155-4167

  Dorival, Jonathan ^a   Annaval, Thibault ^a   Risser, Fanny ^a   Collin, Sabrina ^a   Roblin, Pierre ^b,c   Jacob, Christophe ^a   Gruez, Arnaud ^a   Chagot, Benjamin ^a   Weissman, Kira J ^a  

^a UNIVERSITÉ DE LORRAINE   (France)

^b SYNCHROTRON SOLEIL   (France)

^c INRA   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; KETONES; METABOLITES; PLANTS (BOTANY); PROTEINS;

ACYL CARRIER PROTEINS; INTERSUBUNIT INTERFACE; INTRINSICALLY DISORDERED PROTEINS; MULTIPLE CHARACTERISTICS; PROTEIN-PROTEIN COMPLEXES; SECONDARY METABOLITES; SITE DIRECTED MUTAGENESIS; SPECIFIC RECOGNITION;

X RAY SCATTERING;

GENOMIC DNA; INTRINSICALLY DISORDERED PROTEIN; POLYKETIDE SYNTHASE; UNCLASSIFIED DRUG; VIRGINIAMYCIN; VIRGINIAMYCIN TRANS ACYLTRANSFERASE POLYKETIDE SYNTHASE; ACYLTRANSFERASE;

ARTICLE; CIRCULAR DICHROISM; COMPLEX FORMATION; COMPUTER MODEL; CONFORMATIONAL TRANSITION; ENZYME ACTIVE SITE; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR DOCKING; MOLECULAR MODEL; MOLECULAR WEIGHT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; SITE DIRECTED MUTAGENESIS; STATIC ELECTRICITY; STREPTOMYCES; STREPTOMYCES VIRGINIAE; X RAY CRYSTALLOGRAPHY; CHEMISTRY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ACYLTRANSFERASES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; POLYKETIDE SYNTHASES; VIRGINIAMYCIN;

EID: 84964319329     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.5b13372     Document Type: Article

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