Erythromycin biosynthesis: Kinetic studies on a fully active modular polyketide synthase using natural and unnatural substrates

Biochemistry

Volumn 35, Issue 7, 1996, Pages 2054-2060

  Pieper, Rembert ^a   Ebert Khosla, Susanne ^a   Cane, David ^b   Khosla, Chaitan ^a  

^a Stanford University ^*  (United States)

^b BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A; CARBON 14; ERYTHROMYCIN; LACTONE; MACROLIDE; POLYKETIDE; PROPIONYL COENZYME A; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SYNTHETASE;

ARTICLE; BIOSYNTHESIS; CATALYSIS; CELL FREE SYSTEM; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME SUBSTRATE; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES; STEADY STATE;

ACYL COENZYME A; CARBOXYLIC ACIDS; ERYTHROMYCIN; KINETICS; MULTIENZYME COMPLEXES; NADP; PHOSPHATES; STREPTOMYCES; SUBSTRATE SPECIFICITY;

EID: 0030049982     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi952860b     Document Type: Article

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