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Volumn 14, Issue 1, 2014, Pages

Antimicrobial susceptibility of Neisseria gonorrhoeae isolates from symptomatic men attending the Nanjing sexually transmitted diseases clinic (2011-2012): Genetic characteristics of isolates with reduced sensitivity to ceftriaxone

Author keywords

Antimicrobial resistance; Ceftriaxone; Neisseria gonorrhoeae; Resistance determinants; Resistance plasmids

Indexed keywords

BETA LACTAMASE; CEFTRIAXONE; CIPROFLOXACIN; PENICILLIN DERIVATIVE; SPECTINOMYCIN; TETRACYCLINE; ANTIINFECTIVE AGENT;

EID: 84964315850     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/s12879-014-0622-0     Document Type: Article
Times cited : (19)

References (89)
  • 3
    • 33749512799 scopus 로고    scopus 로고
    • Antibiotic resistance in Neisseria gonorrhoeae is diminishing available treatment options for gonorrhea: some possible remedies
    • Tapsall J: Antibiotic resistance in Neisseria gonorrhoeae is diminishing available treatment options for gonorrhea: some possible remedies. Expert Rev Anti Infect Ther 2006, 4:619-628.
    • (2006) Expert Rev Anti Infect Ther , vol.4 , pp. 619-628
    • Tapsall, J.1
  • 4
    • 84857737837 scopus 로고    scopus 로고
    • Antibiotic resistance in Neisseria gonorrhoeae: origin, evolution, and lessons learned for the future
    • Unemo M, Shafer WM: Antibiotic resistance in Neisseria gonorrhoeae: origin, evolution, and lessons learned for the future. Ann N Y Acad Sci 2011, 1230:E19-E28.
    • (2011) Ann N Y Acad Sci , vol.1230 , pp. E19-E28
    • Unemo, M.1    Shafer, W.M.2
  • 5
    • 79955441458 scopus 로고    scopus 로고
    • Gonorrhoea treatment failures to cefixime and azithromycin in England, 2010
    • Ison CA, Hussey J, Sankar KN, Evans J, Alexander S: Gonorrhoea treatment failures to cefixime and azithromycin in England, 2010. Euro Surveill 2011, 16(14).
    • (2011) Euro Surveill , vol.16 , Issue.14
    • Ison, C.A.1    Hussey, J.2    Sankar, K.N.3    Evans, J.4    Alexander, S.5
  • 6
    • 84870891391 scopus 로고    scopus 로고
    • Emergence of multidrug-resistant, extensively drug-resistant and untreatable gonorrhea
    • Unemo M, Nicholas RA: Emergence of multidrug-resistant, extensively drug-resistant and untreatable gonorrhea. Future Microbiol 2012, 7:1401-1422.
    • (2012) Future Microbiol , vol.7 , pp. 1401-1422
    • Unemo, M.1    Nicholas, R.A.2
  • 7
    • 65649083059 scopus 로고    scopus 로고
    • The use of cephalosporins for gonorrhea: the impending problem of resistance
    • Barry PM, Klausner JD: The use of cephalosporins for gonorrhea: the impending problem of resistance. Expert Opin Pharmacother 2009, 10:555-577.
    • (2009) Expert Opin Pharmacother , vol.10 , pp. 555-577
    • Barry, P.M.1    Klausner, J.D.2
  • 8
    • 78649801372 scopus 로고    scopus 로고
    • Two cases of verified clinical failures using internationally recommended first-line cefixime for gonorrhoea treatment, Norway, 2010
    • Unemo M, Golparian D, Syversen G, Vestrheim DF, Moi H: Two cases of verified clinical failures using internationally recommended first-line cefixime for gonorrhoea treatment, Norway, 2010. Euro Surveill 2010, 15(47).
    • (2010) Euro Surveill , vol.15 , Issue.47
    • Unemo, M.1    Golparian, D.2    Syversen, G.3    Vestrheim, D.F.4    Moi, H.5
  • 9
    • 79959189164 scopus 로고    scopus 로고
    • Is Neisseria gonorrhoeae initiating a future era of untreatable gonorrhea?: detailed characterization of the first strain with high-level resistance to ceftriaxone
    • Ohnishi M, Golparian D, Shimuta K, Saika T, Hoshina S, Iwasaku K, Nakayama S, Kitawaki J, Unemo M: Is Neisseria gonorrhoeae initiating a future era of untreatable gonorrhea?: detailed characterization of the first strain with high-level resistance to ceftriaxone. Antimicrob Agents Chemother 2011, 55:3538-3545.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 3538-3545
    • Ohnishi, M.1    Golparian, D.2    Shimuta, K.3    Saika, T.4    Hoshina, S.5    Iwasaku, K.6    Nakayama, S.7    Kitawaki, J.8    Unemo, M.9
  • 10
    • 84862838826 scopus 로고    scopus 로고
    • Treatment failure of pharyngeal gonorrhoea with internationally recommended first-line ceftriaxone verified in Slovenia, September 2011
    • Unemo M, Golparian D, Potocnik M, Jeverica S: Treatment failure of pharyngeal gonorrhoea with internationally recommended first-line ceftriaxone verified in Slovenia, September 2011. Euro Surveill 2012, 17(25).
    • (2012) Euro Surveill , vol.17 , Issue.25
    • Unemo, M.1    Golparian, D.2    Potocnik, M.3    Jeverica, S.4
  • 11
    • 67650488213 scopus 로고    scopus 로고
    • Two cases of failed ceftriaxone treatment in pharyngeal gonorrhoea verified by molecular microbiological methods
    • Tapsall J, Read P, Carmody C, Bourne C, Ray S, Limnios A, Sloots T, Whiley D: Two cases of failed ceftriaxone treatment in pharyngeal gonorrhoea verified by molecular microbiological methods. J Med Microbiol 2009, 58:683-687.
    • (2009) J Med Microbiol , vol.58 , pp. 683-687
    • Tapsall, J.1    Read, P.2    Carmody, C.3    Bourne, C.4    Ray, S.5    Limnios, A.6    Sloots, T.7    Whiley, D.8
  • 13
    • 45749158073 scopus 로고    scopus 로고
    • Analysis of amino acid sequences of penicillin-binding protein 2 in clinical isolates of Neisseria gonorrhoeae with reduced susceptibility to cefixime and ceftriaxone
    • Osaka K, Takakura T, Narukawa K, Takahata M, Endo K, Kiyota H, Onodera S: Analysis of amino acid sequences of penicillin-binding protein 2 in clinical isolates of Neisseria gonorrhoeae with reduced susceptibility to cefixime and ceftriaxone. J Infect Chemother 2008, 14:195-203.
    • (2008) J Infect Chemother , vol.14 , pp. 195-203
    • Osaka, K.1    Takakura, T.2    Narukawa, K.3    Takahata, M.4    Endo, K.5    Kiyota, H.6    Onodera, S.7
  • 14
    • 59449108342 scopus 로고    scopus 로고
    • Crystal structures of penicillin-binding protein 2 from penicillin-susceptible and-resistant strains of Neisseria gonorrhoeae reveal an unexpectedly subtle mechanism for antibiotic resistance
    • Powell AJ, Tomberg J, Deacon AM, Nicholas RA, Davies C: Crystal structures of penicillin-binding protein 2 from penicillin-susceptible and-resistant strains of Neisseria gonorrhoeae reveal an unexpectedly subtle mechanism for antibiotic resistance. J Biol Chem 2009, 284:1202-1212.
    • (2009) J Biol Chem , vol.284 , pp. 1202-1212
    • Powell, A.J.1    Tomberg, J.2    Deacon, A.M.3    Nicholas, R.A.4    Davies, C.5
  • 15
    • 35948939272 scopus 로고    scopus 로고
    • Diversity of penA alterations and subtypes in Neisseria gonorrhoeae strains from Sydney, Australia, that are less susceptible to ceftriaxone
    • Whiley DM, Limnios EA, Ray S, Sloots TP, Tapsall JW: Diversity of penA alterations and subtypes in Neisseria gonorrhoeae strains from Sydney, Australia, that are less susceptible to ceftriaxone. Antimicrob Agents Chemother 2007, 51:3111-3116.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 3111-3116
    • Whiley, D.M.1    Limnios, E.A.2    Ray, S.3    Sloots, T.P.4    Tapsall, J.W.5
  • 16
    • 77954747876 scopus 로고    scopus 로고
    • Reduced susceptibility to ceftriaxone in Neisseria gonorrhoeae is associated with mutations G542S, P551S and P551L in the gonococcal penicillin-binding protein 2
    • Whiley DM, Goire N, Lambert SB, Ray S, Limnios EA, Nissen MD, Sloots TP, Tapsall JW: Reduced susceptibility to ceftriaxone in Neisseria gonorrhoeae is associated with mutations G542S, P551S and P551L in the gonococcal penicillin-binding protein 2. J Antimicrob Chemother 2010, 65:1615-1618.
    • (2010) J Antimicrob Chemother , vol.65 , pp. 1615-1618
    • Whiley, D.M.1    Goire, N.2    Lambert, S.B.3    Ray, S.4    Limnios, E.A.5    Nissen, M.D.6    Sloots, T.P.7    Tapsall, J.W.8
  • 17
    • 52649131941 scopus 로고    scopus 로고
    • Clinically relevant mutations that cause derepression of the Neisseria gonorrhoeae MtrC-MtrD-MtrE Efflux pump system confer different levels of antimicrobial resistance and in vivo fitness
    • Warner DM, Shafer WM, Jerse AE: Clinically relevant mutations that cause derepression of the Neisseria gonorrhoeae MtrC-MtrD-MtrE Efflux pump system confer different levels of antimicrobial resistance and in vivo fitness. Mol Microbiol 2008, 70:462-478.
    • (2008) Mol Microbiol , vol.70 , pp. 462-478
    • Warner, D.M.1    Shafer, W.M.2    Jerse, A.E.3
  • 18
    • 0028906903 scopus 로고
    • Resistance of Neisseria gonorrhoeae to antimicrobial hydrophobic agents is modulated by the mtrRCDE efflux system
    • Hagman KE, Pan W, Spratt BG, Balthazar JT, Judd RC, Shafer WM: Resistance of Neisseria gonorrhoeae to antimicrobial hydrophobic agents is modulated by the mtrRCDE efflux system. Microbiology 1995, 141(Pt 3):611-622.
    • (1995) Microbiology , vol.141 , pp. 611-622
    • Hagman, K.E.1    Pan, W.2    Spratt, B.G.3    Balthazar, J.T.4    Judd, R.C.5    Shafer, W.M.6
  • 19
    • 0031753295 scopus 로고    scopus 로고
    • Gonococcal resistance to beta-lactams and tetracycline involves mutation in loop 3 of the porin encoded at the penB locus
    • Gill MJ, Simjee S, Al-Hattawi K, Robertson BD, Easmon CS, Ison CA: Gonococcal resistance to beta-lactams and tetracycline involves mutation in loop 3 of the porin encoded at the penB locus. Antimicrob Agents Chemother 1998, 42:2799-2803.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 2799-2803
    • Gill, M.J.1    Simjee, S.2    Al-Hattawi, K.3    Robertson, B.D.4    Easmon, C.S.5    Ison, C.A.6
  • 20
    • 0036171501 scopus 로고    scopus 로고
    • Mutations in ponA, the gene encoding penicillin-binding protein 1, and a novel locus, penC, are required for high-level chromosomally mediated penicillin resistance in Neisseria gonorrhoeae
    • Ropp PA, Hu M, Olesky M, Nicholas RA: Mutations in ponA, the gene encoding penicillin-binding protein 1, and a novel locus, penC, are required for high-level chromosomally mediated penicillin resistance in Neisseria gonorrhoeae. Antimicrob Agents Chemother 2002, 46:769-777.
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 769-777
    • Ropp, P.A.1    Hu, M.2    Olesky, M.3    Nicholas, R.A.4
  • 21
    • 23844463837 scopus 로고    scopus 로고
    • The penC mutation conferring antibiotic resistance in Neisseria gonorrhoeae arises from a mutation in the PilQ secretin that interferes with multimer stability
    • Zhao S, Tobiason DM, Hu M, Seifert HS, Nicholas RA: The penC mutation conferring antibiotic resistance in Neisseria gonorrhoeae arises from a mutation in the PilQ secretin that interferes with multimer stability. Mol Microbiol 2005, 57:1238-1251.
    • (2005) Mol Microbiol , vol.57 , pp. 1238-1251
    • Zhao, S.1    Tobiason, D.M.2    Hu, M.3    Seifert, H.S.4    Nicholas, R.A.5
  • 22
    • 78149491898 scopus 로고    scopus 로고
    • Alterations of the pilQ gene in Neisseria gonorrhoeae are unlikely contributors to decreased susceptibility to ceftriaxone and cefixime in clinical gonococcal strains
    • Whiley DM, Jacobsson S, Tapsall JW, Nissen MD, Sloots TP, Unemo M: Alterations of the pilQ gene in Neisseria gonorrhoeae are unlikely contributors to decreased susceptibility to ceftriaxone and cefixime in clinical gonococcal strains. J Antimicrob Chemother 2010, 65:2543-2547.
    • (2010) J Antimicrob Chemother , vol.65 , pp. 2543-2547
    • Whiley, D.M.1    Jacobsson, S.2    Tapsall, J.W.3    Nissen, M.D.4    Sloots, T.P.5    Unemo, M.6
  • 23
    • 70349135516 scopus 로고    scopus 로고
    • Genetics of chromosomally mediated intermediate resistance to ceftriaxone and cefixime in Neisseria gonorrhoeae
    • Zhao S, Duncan M, Tomberg J, Davies C, Unemo M, Nicholas RA: Genetics of chromosomally mediated intermediate resistance to ceftriaxone and cefixime in Neisseria gonorrhoeae. Antimicrob Agents Chemother 2009, 53:3744-3751.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 3744-3751
    • Zhao, S.1    Duncan, M.2    Tomberg, J.3    Davies, C.4    Unemo, M.5    Nicholas, R.A.6
  • 27
    • 79960729480 scopus 로고    scopus 로고
    • Surveillance of antibiotic resistance in Neisseria gonorrhoeae in the WHO Western Pacific and South East Asian Regions, 2009
    • W. H. O. Western Pacific South East Asian Gonococcal Antimicrobial Surveillance, Programmes: Surveillance of antibiotic resistance in Neisseria gonorrhoeae in the WHO Western Pacific and South East Asian Regions, 2009. Commun Dis Intell Q Rep 2011, 35:2-7.
    • (2011) Commun Dis Intell Q Rep , vol.35 , pp. 2-7
  • 28
    • 84870987947 scopus 로고    scopus 로고
    • Surveillance of antibiotic resistance in Neisseria gonorrhoeae in the WHO Western Pacific and South East Asian Regions, 2010
    • Lahra MM, WHO Western Pacific South East Asian Gonococcal Antimicrobial Surveillance Programme: Surveillance of antibiotic resistance in Neisseria gonorrhoeae in the WHO Western Pacific and South East Asian Regions, 2010. Commun Dis Intell Q Rep 2012, 36:95-100.
    • (2012) Commun Dis Intell Q Rep , vol.36 , pp. 95-100
    • Lahra, M.M.1
  • 29
    • 79959922373 scopus 로고    scopus 로고
    • Surveillance of antibiotic susceptibility of Neisseria gonorrhoeae in the WHO western Pacific region 1992-4
    • WHO Western Pacific Region Gonococcal Antimicrobial Surveillance Programme: Surveillance of antibiotic susceptibility of Neisseria gonorrhoeae in the WHO western Pacific region 1992-4. Genitourin Med 1997, 73:355-361.
    • (1997) Genitourin Med , vol.73 , pp. 355-361
  • 30
    • 71049150745 scopus 로고    scopus 로고
    • Edited by Wang QQ, Zhang GC. Shanghai: Shanghai Scientific and Technological Literature Press;
    • National Center for STD Control, China CDC: Gonorrhea. In Guidelines for Diagnosis and Treatment of Sexually Transmitted Diseases [in Chinese]. Edited by Wang QQ, Zhang GC. Shanghai: Shanghai Scientific and Technological Literature Press; 2007.
    • (2007) Guidelines for Diagnosis and Treatment of Sexually Transmitted Diseases [in Chinese]
  • 31
    • 84891852867 scopus 로고    scopus 로고
    • Monitoring antimicrobial resistance in Neisseria gonorrhoeae in selected countries of the WHO South-East Asia Region between 2009 and 2012: a retrospective analysis
    • Bala M, Kakran M, Singh V, Sood S, Ramesh V, Members of WHOGSN: Monitoring antimicrobial resistance in Neisseria gonorrhoeae in selected countries of the WHO South-East Asia Region between 2009 and 2012: a retrospective analysis. Sex Transm Infect 2013, 89(4):iv28-iv35.
    • (2013) Sex Transm Infect , vol.89 , Issue.4 , pp. iv28-iv35
    • Bala, M.1    Kakran, M.2    Singh, V.3    Sood, S.4    Ramesh, V.5
  • 32
    • 84882620294 scopus 로고    scopus 로고
    • Decreased susceptibility to cephalosporins among gonococci: data from the Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP) in England and Wales, 2007-2011
    • Ison CA, Town K, Obi C, Chisholm S, Hughes G, Livermore DM, Lowndes CM, GRASP collaborative group: Decreased susceptibility to cephalosporins among gonococci: data from the Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP) in England and Wales, 2007-2011. Lancet Infect Dis 2013, 13:762-768.
    • (2013) Lancet Infect Dis , vol.13 , pp. 762-768
    • Ison, C.A.1    Town, K.2    Obi, C.3    Chisholm, S.4    Hughes, G.5    Livermore, D.M.6    Lowndes, C.M.7
  • 33
    • 84891859404 scopus 로고    scopus 로고
    • Trends in antimicrobial resistance in Neisseria gonorrhoeae in the USA: the Gonococcal Isolate Surveillance Project (GISP), January 2006-June 2012
    • Kirkcaldy RD, Kidd S, Weinstock HS, Papp JR, Bolan GA: Trends in antimicrobial resistance in Neisseria gonorrhoeae in the USA: the Gonococcal Isolate Surveillance Project (GISP), January 2006-June 2012. Sex Transm Infect 2013, 89(4):iv5-iv10.
    • (2013) Sex Transm Infect , vol.89 , Issue.4 , pp. iv5-iv10
    • Kirkcaldy, R.D.1    Kidd, S.2    Weinstock, H.S.3    Papp, J.R.4    Bolan, G.A.5
  • 36
    • 79960394084 scopus 로고    scopus 로고
    • Gonorrhoea in men: clinical and diagnostic aspects
    • Sherrard J, Barlow D: Gonorrhoea in men: clinical and diagnostic aspects. Genitourin Med 1996, 72:422-426.
    • (1996) Genitourin Med , vol.72 , pp. 422-426
    • Sherrard, J.1    Barlow, D.2
  • 38
    • 84864505639 scopus 로고    scopus 로고
    • Molecular characterization of two high-level ceftriaxone-resistant Neisseria gonorrhoeae isolates detected in Catalonia, Spain
    • Camara J, Serra J, Ayats J, Bastida T, Carnicer-Pont D, Andreu A, Ardanuy C: Molecular characterization of two high-level ceftriaxone-resistant Neisseria gonorrhoeae isolates detected in Catalonia, Spain. J Antimicrob Chemother 2012, 67:1858-1860.
    • (2012) J Antimicrob Chemother , vol.67 , pp. 1858-1860
    • Camara, J.1    Serra, J.2    Ayats, J.3    Bastida, T.4    Carnicer-Pont, D.5    Andreu, A.6    Ardanuy, C.7
  • 39
    • 36348946875 scopus 로고    scopus 로고
    • Surveillance of antimicrobial susceptibilities in Neisseria gonorrhoeae in Nanjing, China, 1999-2006
    • Su X, Jiang F, Qimuge, Dai X, Sun H, Ye S: Surveillance of antimicrobial susceptibilities in Neisseria gonorrhoeae in Nanjing, China, 1999-2006. Sex Transm Dis 2007, 34:995-999.
    • (2007) Sex Transm Dis , vol.34 , pp. 995-999
    • Su, X.1    Jiang, F.2    Qimuge, D.3    Dai, X.4    Sun, H.5    Ye, S.6
  • 40
    • 0019493481 scopus 로고
    • Simple method for detecting penicillinaseproducing Neisseria gonorrhoeae and Staphylococcus aureus
    • Sng EH, Yeo KL, Rajan VS: Simple method for detecting penicillinaseproducing Neisseria gonorrhoeae and Staphylococcus aureus. Br J Vener Dis 1981, 57:141-142.
    • (1981) Br J Vener Dis , vol.57 , pp. 141-142
    • Sng, E.H.1    Yeo, K.L.2    Rajan, V.S.3
  • 41
    • 0027915836 scopus 로고
    • Sentinel surveillance for antimicrobial resistance in Neisseria gonorrhoeae-United States, 1988-1991. The Gonococcal Isolate Surveillance Project Study Group
    • Gorwitz RJ, Nakashima AK, Moran JS, Knapp JS: Sentinel surveillance for antimicrobial resistance in Neisseria gonorrhoeae-United States, 1988-1991. The Gonococcal Isolate Surveillance Project Study Group. MMWR CDC Surveill Summ 1993, 42:29-39.
    • (1993) MMWR CDC Surveill Summ , vol.42 , pp. 29-39
    • Gorwitz, R.J.1    Nakashima, A.K.2    Moran, J.S.3    Knapp, J.S.4
  • 42
    • 0033023829 scopus 로고    scopus 로고
    • Molecular epidemiology of tetM genes in Neisseria gonorrhoeae
    • Turner A, Gough KR, Leeming JP: Molecular epidemiology of tetM genes in Neisseria gonorrhoeae. Sex Transm Infect 1999, 75:60-66.
    • (1999) Sex Transm Infect , vol.75 , pp. 60-66
    • Turner, A.1    Gough, K.R.2    Leeming, J.P.3
  • 43
    • 0034078256 scopus 로고    scopus 로고
    • A multiplex polymerase chain reaction to differentiate beta-lactamase plasmids of neisseria gonorrhoeae
    • Palmer HM, Leeming JP, Turner A: A multiplex polymerase chain reaction to differentiate beta-lactamase plasmids of neisseria gonorrhoeae. J Antimicrob Chemother 2000, 45:777-782.
    • (2000) J Antimicrob Chemother , vol.45 , pp. 777-782
    • Palmer, H.M.1    Leeming, J.P.2    Turner, A.3
  • 44
    • 79954569209 scopus 로고    scopus 로고
    • Analysis of mutations in multiple loci of Neisseria gonorrhoeae isolates reveals effects of PIB, PBP2 and MtrR on reduced susceptibility to ceftriaxone
    • Liao M, Gu WM, Yang Y, Dillon JA: Analysis of mutations in multiple loci of Neisseria gonorrhoeae isolates reveals effects of PIB, PBP2 and MtrR on reduced susceptibility to ceftriaxone. J Antimicrob Chemother 2011, 66:1016-1023.
    • (2011) J Antimicrob Chemother , vol.66 , pp. 1016-1023
    • Liao, M.1    Gu, W.M.2    Yang, Y.3    Dillon, J.A.4
  • 45
    • 77952570638 scopus 로고    scopus 로고
    • Various penA mutations together with mtrR, porB and ponA mutations in Neisseria gonorrhoeae isolates with reduced susceptibility to cefixime or ceftriaxone
    • Lee SG, Lee H, Jeong SH, Yong D, Chung GT, Lee YS, Chong Y, Lee K: Various penA mutations together with mtrR, porB and ponA mutations in Neisseria gonorrhoeae isolates with reduced susceptibility to cefixime or ceftriaxone. J Antimicrob Chemother 2010, 65:669-675.
    • (2010) J Antimicrob Chemother , vol.65 , pp. 669-675
    • Lee, S.G.1    Lee, H.2    Jeong, S.H.3    Yong, D.4    Chung, G.T.5    Lee, Y.S.6    Chong, Y.7    Lee, K.8
  • 47
    • 84858705834 scopus 로고    scopus 로고
    • Emergence and characterization of Neisseria gonorrhoeae isolates with decreased susceptibilities to ceftriaxone and cefixime in Canada: 2001-2010
    • Martin I, Sawatzky P, Allen V, Hoang L, Lefebvre B, Mina N, Wong T, Gilmour M: Emergence and characterization of Neisseria gonorrhoeae isolates with decreased susceptibilities to ceftriaxone and cefixime in Canada: 2001-2010. Sex Transm Dis 2012, 39:316-323.
    • (2012) Sex Transm Dis , vol.39 , pp. 316-323
    • Martin, I.1    Sawatzky, P.2    Allen, V.3    Hoang, L.4    Lefebvre, B.5    Mina, N.6    Wong, T.7    Gilmour, M.8
  • 48
    • 84871620371 scopus 로고    scopus 로고
    • The role of penicillin-binding protein 2 (PBP2) in the cephalosporin susceptibility of Neisseria gonorrhoeae and the need for consensus in naming of PBP2
    • Chen CC, Lin KY, Li SY: The role of penicillin-binding protein 2 (PBP2) in the cephalosporin susceptibility of Neisseria gonorrhoeae and the need for consensus in naming of PBP2. J Formos Med Assoc 2012, 111:665-666.
    • (2012) J Formos Med Assoc , vol.111 , pp. 665-666
    • Chen, C.C.1    Lin, K.Y.2    Li, S.Y.3
  • 50
    • 2142695441 scopus 로고    scopus 로고
    • Rapid sequencebased identification of gonococcal transmission clusters in a large metropolitan area
    • Martin IM, Ison CA, Aanensen DM, Fenton KA, Spratt BG: Rapid sequencebased identification of gonococcal transmission clusters in a large metropolitan area. J Infect Dis 2004, 189:1497-1505.
    • (2004) J Infect Dis , vol.189 , pp. 1497-1505
    • Martin, I.M.1    Ison, C.A.2    Aanensen, D.M.3    Fenton, K.A.4    Spratt, B.G.5
  • 51
    • 80455132320 scopus 로고    scopus 로고
    • A novel mechanism of high-level, broad-spectrum antibiotic resistance caused by a single base pair change in Neisseria gonorrhoeae
    • Ohneck EA, Zalucki YM, Johnson PJ, Dhulipala V, Golparian D, Unemo M, Jerse AE, Shafer WM: A novel mechanism of high-level, broad-spectrum antibiotic resistance caused by a single base pair change in Neisseria gonorrhoeae. MBio 2011, 2:e00187-11.
    • (2011) MBio , vol.2
    • Ohneck, E.A.1    Zalucki, Y.M.2    Johnson, P.J.3    Dhulipala, V.4    Golparian, D.5    Unemo, M.6    Jerse, A.E.7    Shafer, W.M.8
  • 52
    • 84990036717 scopus 로고    scopus 로고
    • Study of antimicrobial susceptibilities and molecular resistance determines in Neisseria gonorrhoeae isolated in Shanghai
    • Yang Y, WL ZC, Gu W: Study of antimicrobial susceptibilities and molecular resistance determines in Neisseria gonorrhoeae isolated in Shanghai. Chin J Lab Med 2009, 32:1173-1175.
    • (2009) Chin J Lab Med , vol.32 , pp. 1173-1175
    • Yang, Y.1    Liu, Z.C.2    Gu, W.3
  • 54
    • 84990036710 scopus 로고    scopus 로고
    • Analysis on the drug-resistance of Nersseria gonorrhoeae to antibiotics in Hainan area from 2006-2011
    • Zhong N, ZW WF, Zhang LF, Lu YZ: Analysis on the drug-resistance of Nersseria gonorrhoeae to antibiotics in Hainan area from 2006-2011. Chin J Derm Venereol 2013, 27:56-57.
    • (2013) Chin J Derm Venereol , vol.27 , pp. 56-57
    • Zhong, N.1    Zheng, W.F.2    Zhang, L.F.3    Lu, Y.Z.4
  • 55
    • 84872680077 scopus 로고    scopus 로고
    • Antimicrobial susceptibility and genetic characteristics of Neisseria gonorrhoeae isolates from India, Pakistan and Bhutan in 2007-2011
    • Sethi S, Golparian D, Bala M, Dorji D, Ibrahim M, Jabeen K, Unemo M: Antimicrobial susceptibility and genetic characteristics of Neisseria gonorrhoeae isolates from India, Pakistan and Bhutan in 2007-2011. BMC Infect Dis 2013, 13:35.
    • (2013) BMC Infect Dis , vol.13 , pp. 35
    • Sethi, S.1    Golparian, D.2    Bala, M.3    Dorji, D.4    Ibrahim, M.5    Jabeen, K.6    Unemo, M.7
  • 56
    • 84872769585 scopus 로고    scopus 로고
    • Antimicrobial susceptibility and genetic characteristics of Neisseria gonorrhoeae isolates from Vietnam, 2011
    • Olsen B, Pham TL, Golparian D, Johansson E, Tran HK, Unemo M: Antimicrobial susceptibility and genetic characteristics of Neisseria gonorrhoeae isolates from Vietnam, 2011. BMC Infect Dis 2013, 13:40.
    • (2013) BMC Infect Dis , vol.13 , pp. 40
    • Olsen, B.1    Pham, T.L.2    Golparian, D.3    Johansson, E.4    Tran, H.K.5    Unemo, M.6
  • 57
    • 80054096932 scopus 로고    scopus 로고
    • Trends in antimicrobial resistance of Neisseria gonorrhoeae isolated from Korean patients from 2000 to 2006
    • Lee H, Hong SG, Soe Y, Yong D, Jeong SH, Lee K, Chong Y: Trends in antimicrobial resistance of Neisseria gonorrhoeae isolated from Korean patients from 2000 to 2006. Sex Transm Dis 2011, 38:1082-1086.
    • (2011) Sex Transm Dis , vol.38 , pp. 1082-1086
    • Lee, H.1    Hong, S.G.2    Soe, Y.3    Yong, D.4    Jeong, S.H.5    Lee, K.6    Chong, Y.7
  • 58
    • 80052969760 scopus 로고    scopus 로고
    • Trends in antimicrobial resistance in Neisseria gonorrhoeae isolated in Canada: 2000-2009
    • Martin I, Jayaraman G, Wong T, Liu G, Gilmour M, Canadian Public Health Laboratory Network: Trends in antimicrobial resistance in Neisseria gonorrhoeae isolated in Canada: 2000-2009. Sex Transm Dis 2011, 38:892-898.
    • (2011) Sex Transm Dis , vol.38 , pp. 892-898
    • Martin, I.1    Jayaraman, G.2    Wong, T.3    Liu, G.4    Gilmour, M.5
  • 59
    • 84891842227 scopus 로고    scopus 로고
    • Two decades of the gonococcal antimicrobial surveillance program in South America and the Caribbean: challenges and opportunities
    • Dillon JA, Trecker MA, Thakur SD, Gonococcal Antimicrobial Surveillance Program Network in Latin A, Caribbean: Two decades of the gonococcal antimicrobial surveillance program in South America and the Caribbean: challenges and opportunities. Sex Transm Infect 2013, 89(4):iv36-iv41.
    • (2013) Sex Transm Infect , vol.89 , Issue.4 , pp. iv36-iv41
    • Dillon, J.A.1    Trecker, M.A.2    Thakur, S.D.3
  • 62
    • 78449240179 scopus 로고    scopus 로고
    • European surveillance of antimicrobial resistance in Neisseria gonorrhoeae
    • Cole MJ, Chisholm SA, Hoffmann S, Stary A, Lowndes CM, Ison CA, European Surveillance of Sexually Transmitted Infections Network: European surveillance of antimicrobial resistance in Neisseria gonorrhoeae. Sex Transm Infect 2010, 86:427-432.
    • (2010) Sex Transm Infect , vol.86 , pp. 427-432
    • Cole, M.J.1    Chisholm, S.A.2    Hoffmann, S.3    Stary, A.4    Lowndes, C.M.5    Ison, C.A.6
  • 64
    • 84862318667 scopus 로고    scopus 로고
    • Australian Gonococcal Surveillance Programme annual report, 2010
    • Australian Gonococcal Surveillance P: Australian Gonococcal Surveillance Programme annual report, 2010. Commun Dis Intell Q Rep 2011, 35:229-236.
    • (2011) Commun Dis Intell Q Rep , vol.35 , pp. 229-236
    • Australian Gonococcal Surveillance, P.1
  • 67
    • 84884922548 scopus 로고    scopus 로고
    • Phenotypic and genetic characterization of the first two cases of extended-spectrum-cephalosporin-resistant Neisseria gonorrhoeae infection in South Africa and association with cefixime treatment failure
    • Lewis DA, Sriruttan C, Muller EE, Golparian D, Gumede L, Fick D, de Wet J, Maseko V, Coetzee J, Unemo M: Phenotypic and genetic characterization of the first two cases of extended-spectrum-cephalosporin-resistant Neisseria gonorrhoeae infection in South Africa and association with cefixime treatment failure. J Antimicrob Chemother 2013, 68:1267-1270.
    • (2013) J Antimicrob Chemother , vol.68 , pp. 1267-1270
    • Lewis, D.A.1    Sriruttan, C.2    Muller, E.E.3    Golparian, D.4    Gumede, L.5    Fick, D.6    de Wet, J.7    Maseko, V.8    Coetzee, J.9    Unemo, M.10
  • 70
    • 79960262635 scopus 로고    scopus 로고
    • Cephalosporin susceptibility among Neisseria gonorrhoeae isolates-United States, 2000-2010
    • Centers for Disease Control and Prevention: Cephalosporin susceptibility among Neisseria gonorrhoeae isolates-United States, 2000-2010. MMWR Morb Mortal Wkly Rep 2011, 60:873-877.
    • (2011) MMWR Morb Mortal Wkly Rep , vol.60 , pp. 873-877
  • 71
    • 84872862875 scopus 로고    scopus 로고
    • Neisseria gonorrhoeae strain with high-level resistance to spectinomycin due to a novel resistance mechanism (mutated ribosomal protein S5) verified in Norway
    • Unemo M, Golparian D, Skogen V, Olsen AO, Moi H, Syversen G, Hjelmevoll SO: Neisseria gonorrhoeae strain with high-level resistance to spectinomycin due to a novel resistance mechanism (mutated ribosomal protein S5) verified in Norway. Antimicrob Agents Chemother 2013, 57:1057-1061.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 1057-1061
    • Unemo, M.1    Golparian, D.2    Skogen, V.3    Olsen, A.O.4    Moi, H.5    Syversen, G.6    Hjelmevoll, S.O.7
  • 73
    • 0017103415 scopus 로고
    • Beta-lactamase-producing, penicillin-resistant gonococcus
    • Phillips I: Beta-lactamase-producing, penicillin-resistant gonococcus. Lancet 1976, 2:656-657.
    • (1976) Lancet , vol.2 , pp. 656-657
    • Phillips, I.1
  • 74
    • 0024558061 scopus 로고
    • Beta-lactamase plasmids and chromosomally mediated antibiotic resistance in pathogenic Neisseria species
    • Dillon JA, Yeung KH: Beta-lactamase plasmids and chromosomally mediated antibiotic resistance in pathogenic Neisseria species. Clin Microbiol Rev 1989, 2(Suppl):S125-S133.
    • (1989) Clin Microbiol Rev , vol.2 , pp. S125-S133
    • Dillon, J.A.1    Yeung, K.H.2
  • 75
    • 79953214377 scopus 로고    scopus 로고
    • Plasmid-mediated penicillin and tetracycline resistance among Neisseria gonorrhoeae isolates in South Africa: prevalence, detection and typing using a novel molecular assay
    • Fayemiwo SA, Muller EE, Gumede L, Lewis DA: Plasmid-mediated penicillin and tetracycline resistance among Neisseria gonorrhoeae isolates in South Africa: prevalence, detection and typing using a novel molecular assay. Sex Transm Dis 2011, 38:329-333.
    • (2011) Sex Transm Dis , vol.38 , pp. 329-333
    • Fayemiwo, S.A.1    Muller, E.E.2    Gumede, L.3    Lewis, D.A.4
  • 76
    • 84905405829 scopus 로고    scopus 로고
    • Characterisation of a novel Neisseria gonorrhoeae penicillinase-producing plasmid isolated in Australia in 2012
    • Trembizki E, Buckley C, Lawrence A, Lahra M, Whiley D, GRAND Study Investigators: Characterisation of a novel Neisseria gonorrhoeae penicillinase-producing plasmid isolated in Australia in 2012. Antimicrob Agents Chemother 2014, 58:4984-4985.
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 4984-4985
    • Trembizki, E.1    Buckley, C.2    Lawrence, A.3    Lahra, M.4    Whiley, D.5
  • 77
    • 84885908832 scopus 로고    scopus 로고
    • Antimicrobial resistance and molecular typing of Neisseria gonorrhoeae isolates in Kyoto and Osaka, Japan, 2010 to 2012: intensified surveillance after identification of the first strain (H041) with high-level ceftriaxone resistance
    • Shimuta K, Unemo M, Nakayama S, Morita-Ishihara T, Dorin M, Kawahata T, Ohnishi M, Antibiotic-Resistant Gonorrhea Study Group: Antimicrobial resistance and molecular typing of Neisseria gonorrhoeae isolates in Kyoto and Osaka, Japan, 2010 to 2012: intensified surveillance after identification of the first strain (H041) with high-level ceftriaxone resistance. Antimicrob Agents Chemother 2013, 57:5225-5232.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 5225-5232
    • Shimuta, K.1    Unemo, M.2    Nakayama, S.3    Morita-Ishihara, T.4    Dorin, M.5    Kawahata, T.6    Ohnishi, M.7
  • 78
    • 84857146496 scopus 로고    scopus 로고
    • Highlevel cefixime-and ceftriaxone-resistant Neisseria gonorrhoeae in France: novel penA mosaic allele in a successful international clone causes treatment failure
    • Unemo M, Golparian D, Nicholas R, Ohnishi M, Gallay A, Sednaoui P: Highlevel cefixime-and ceftriaxone-resistant Neisseria gonorrhoeae in France: novel penA mosaic allele in a successful international clone causes treatment failure. Antimicrob Agents Chemother 2012, 56:1273-1280.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 1273-1280
    • Unemo, M.1    Golparian, D.2    Nicholas, R.3    Ohnishi, M.4    Gallay, A.5    Sednaoui, P.6
  • 80
    • 78449239981 scopus 로고    scopus 로고
    • Emergence, spread and characteristics of Neisseria gonorrhoeae isolates with in vitro decreased susceptibility and resistance to extended-spectrum cephalosporins in Sweden
    • Golparian D, Hellmark B, Fredlund H, Unemo M: Emergence, spread and characteristics of Neisseria gonorrhoeae isolates with in vitro decreased susceptibility and resistance to extended-spectrum cephalosporins in Sweden. Sex Transm Infect 2010, 86:454-460.
    • (2010) Sex Transm Infect , vol.86 , pp. 454-460
    • Golparian, D.1    Hellmark, B.2    Fredlund, H.3    Unemo, M.4
  • 81
    • 84890117307 scopus 로고    scopus 로고
    • Neisseria gonorrhoeae and extended-spectrum cephalosporins in California: surveillance and molecular detection of mosaic penA
    • Gose S, Nguyen D, Lowenberg D, Samuel M, Bauer H, Pandori M: Neisseria gonorrhoeae and extended-spectrum cephalosporins in California: surveillance and molecular detection of mosaic penA. BMC Infect Dis 2013, 13:570.
    • (2013) BMC Infect Dis , vol.13 , pp. 570
    • Gose, S.1    Nguyen, D.2    Lowenberg, D.3    Samuel, M.4    Bauer, H.5    Pandori, M.6
  • 82
    • 77956565733 scopus 로고    scopus 로고
    • Molecular and structural analysis of mosaic variants of penicillin-binding protein 2 conferring decreased susceptibility to expanded-spectrum cephalosporins in Neisseria gonorrhoeae: role of epistatic mutations
    • Tomberg J, Unemo M, Davies C, Nicholas RA: Molecular and structural analysis of mosaic variants of penicillin-binding protein 2 conferring decreased susceptibility to expanded-spectrum cephalosporins in Neisseria gonorrhoeae: role of epistatic mutations. Biochemistry 2010, 49:8062-8070.
    • (2010) Biochemistry , vol.49 , pp. 8062-8070
    • Tomberg, J.1    Unemo, M.2    Davies, C.3    Nicholas, R.A.4
  • 83
    • 84864993313 scopus 로고    scopus 로고
    • Update to CDC's sexually transmitted diseases treatment guidelines, 2010: oral cephalosporins no longer a recommended treatment for gonococcal infections
    • Centers for Disease Control Prevention: Update to CDC's sexually transmitted diseases treatment guidelines, 2010: oral cephalosporins no longer a recommended treatment for gonococcal infections. MMWR Morb Mortal Wkly Rep 2012, 61:590-594.
    • (2012) MMWR Morb Mortal Wkly Rep , vol.61 , pp. 590-594
  • 84
    • 80054750360 scopus 로고    scopus 로고
    • UK national guideline for the management of gonorrhoea in adults, 2011
    • Bignell C, Fitzgerald M, Guideline Development Group, British Association for Sexual Health and HIV UK: UK national guideline for the management of gonorrhoea in adults, 2011. Int J STD AIDS 2011, 22:541-547.
    • (2011) Int J STD AIDS , vol.22 , pp. 541-547
    • Bignell, C.1    Fitzgerald, M.2
  • 85
    • 84879495636 scopus 로고    scopus 로고
    • 2012 European guideline on the diagnosis and treatment of gonorrhoea in adults
    • Bignell C, Unemo M, European STI Guidelines Editorial Board: 2012 European guideline on the diagnosis and treatment of gonorrhoea in adults. Int J STD AIDS 2013, 24:85-92.
    • (2013) Int J STD AIDS , vol.24 , pp. 85-92
    • Bignell, C.1    Unemo, M.2
  • 87
    • 84886926874 scopus 로고    scopus 로고
    • One confirmed and one suspected case of pharyngeal gonorrhoea treatment failure following 500 mg ceftriaxone in Sydney, Australia
    • Read PJ, Limnios EA, McNulty A, Whiley D, Lahra MM: One confirmed and one suspected case of pharyngeal gonorrhoea treatment failure following 500 mg ceftriaxone in Sydney, Australia. Sex Health 2013, 10:460-462.
    • (2013) Sex Health , vol.10 , pp. 460-462
    • Read, P.J.1    Limnios, E.A.2    McNulty, A.3    Whiley, D.4    Lahra, M.M.5
  • 89
    • 84862537561 scopus 로고    scopus 로고
    • Management of pharyngeal gonorrhea is crucial to prevent the emergence and spread of antibiotic-resistant Neisseria gonorrhoeae
    • author reply 4041-4032
    • Deguchi T, Yasuda M, Ito S: Management of pharyngeal gonorrhea is crucial to prevent the emergence and spread of antibiotic-resistant Neisseria gonorrhoeae. Antimicrob Agents Chemother 2012, 56:4039-4040. author reply 4041-4032.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 4039-4040
    • Deguchi, T.1    Yasuda, M.2    Ito, S.3


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