Management of pharyngeal gonorrhea is crucial to prevent the emergence and spread of antibiotic-resistant Neisseria gonorrhoeae

Antimicrobial Agents and Chemotherapy

Volumn 56, Issue 7, 2012, Pages 4039-4040

  Deguchi, Takashi ^a   Yasuda, Mitsuru ^a   Ito, Shin ^b  

^a GIFU UNIVERSITY   (Japan)

^b IClinic   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; BACTERIAL PROTEIN; CEFIXIME; CEFTRIAXONE; CEPHALOSPORIN DERIVATIVE; PENA PROTEIN; PENICILLIN BINDING PROTEIN; PENICILLIN BINDING PROTEIN 2; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC THERAPY; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM IDENTIFICATION; DRUG TREATMENT FAILURE; GONOCOCCAL URETHRITIS; GONORRHEA; HUMAN; LETTER; MINIMUM INHIBITORY CONCENTRATION; NEISSERIA GONORRHOEAE; NONHUMAN; NUCLEIC ACID AMPLIFICATION; PHARYNGITIS; PHARYNX GONORRHEA; PRIORITY JOURNAL;

ANTI-BACTERIAL AGENTS; CEFIXIME; CEFTRIAXONE; CEPHALOSPORIN RESISTANCE; GONORRHEA; HUMANS; MALE; NEISSERIA GONORRHOEAE;

EID: 84862537561     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00505-12     Document Type: Letter

References (12)

1. Ameyama S, et al. 2002. Mosaic-like structure of penicillin-binding protein 2 gene (penA) in clinical isolates of Neisseria gonorrhoeae with reduced susceptibility to cefixime. Antimicrob. Agents Chemother. 46:3744-3749.
2. Bernstein KT, et al. 2009. Chlamydia trachomatis and Neisseria gonorrhoeae transmission from the oropharynx to the urethra among men who have sex with men. Clin. Infect. Dis. 49:1793-1797.
3. Ito M, et al. 2005. Emergence and spread of Neisseria gonorrhoeae clinical isolates harboring mosaic-like structure of penicillin-binding protein 2 in Central Japan. Antimicrob. Agents Chemother. 49:137-143.
4. Ito M, et al. 2004. Remarkable increase in central Japan in 2001-2002 of Neisseria gonorrhoeae isolates with decreased susceptibility to penicillin, tetracycline, oral cephalosporins, and fluoroquinolones. Antimicrob. Agents Chemother. 48:3185-3187.
5. Ochiai S, Ishiko H, Yasuda M, Deguchi T. 2008. Rapid detection of the mosaic structure of the Neisseria gonorrhoeae penA gene, which is associated with decreased susceptibilities to oral cephalosporins. J. Clin. Microbiol. 46:1804-1810.
6. Ochiai S, et al. 2007. Decreased affinity of mosaic-structure recombinant penicillin-binding protein 2 for oral cephalosporins in Neisseria gonorrhoeae. J. Antimicrob. Chemother. 60:54-60.
7. Ohnishi M, et al. 2011. Is Neisseria gonorrhoeae initiating a future era of untreatable gonorrhea?: detailed characterization of the first strain with high-level resistance to ceftriaxone. Antimicrob. Agents Chemother. 55:3538-3545.
8. Page-Shafer K, et al. 2002. Increased sensitivity of DNA amplification testing for the detection of pharyngeal gonorrhea in men who have sex with men. Clin. Infect. Dis. 34:173-176.
9. Unemo M, Golparian D, Hestner A. 2011. Ceftriaxone treatment failure of pharyngeal gonorrhoea verified by international recommendations, Sweden, July 2010. Euro Surveill. 16(6):pii=19792. http://www.eurosurveillance.org/ ViewArticle.aspx?ArticleId=19792.
10. Unemo M, et al. 2012. High-level cefixime- and ceftriaxone-resistant Neisseria gonorrhoeae in France: novel penA mosaic allele in a successful international clone causes treatment failure. Antimicrob. Agents Chemother. 56:1273-1280.
11. Workowski KA, Berman S, Centers for Disease Control and Prevention. 2010. Sexually transmitted diseases treatment guidelines, 2010. MMWR Recommend. Rep. 59(RR-12):1-110.
12. Yokoi S, et al. 2007. Threat to cefixime treatment for gonorrhea. Emerg. Infect. Dis. 13:1275-1277.