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Volumn 65, Issue 12, 2010, Pages 2543-2547

Alterations of the pilQ gene in Neisseria gonorrhoeae are unlikely contributors to decreased susceptibility to ceftriaxone and cefixime in clinical gonococcal strains

Author keywords

Antimicrobial resistance; Extended spectrum cephalosporins; Gonorrhoea; penA; Third generation

Indexed keywords

CEFIXIME; CEFTRIAXONE;

EID: 78149491898     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkq377     Document Type: Article
Times cited : (36)

References (11)
  • 1
    • 70350627375 scopus 로고    scopus 로고
    • Meeting the public health challenge of multidrug-and extensively drug-resistant Neisseria gonorrhoeae
    • Tapsall JW, Ndowa F, Lewis DA et al. Meeting the public health challenge of multidrug-and extensively drug-resistant Neisseria gonorrhoeae. Expert Rev Anti Infect Ther 2009; 7: 821-34.
    • (2009) Expert Rev Anti Infect Ther , vol.7 , pp. 821-834
    • Tapsall, J.W.1    Ndowa, F.2    Lewis, D.A.3
  • 2
    • 70349135516 scopus 로고    scopus 로고
    • Genetics of chromosomally mediated intermediate resistance to ceftriaxone and cefixime in Neisseria gonorrhoeae
    • Zhao S, Duncan M, Tomberg J et al. Genetics of chromosomally mediated intermediate resistance to ceftriaxone and cefixime in Neisseria gonorrhoeae. Antimicrob Agents Chemother 2009; 53: 3744-51.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 3744-3751
    • Zhao, S.1    Duncan, M.2    Tomberg, J.3
  • 3
    • 35948939272 scopus 로고    scopus 로고
    • Diversity of penA alterations and subtypes in Neisseria gonorrhoeae strains from Sydney, Australia, that are less susceptible to ceftriaxone
    • Whiley DM, Limnios EA, Ray S et al. Diversity of penA alterations and subtypes in Neisseria gonorrhoeae strains from Sydney, Australia, that are less susceptible to ceftriaxone. Antimicrob Agents Chemother 2007; 51: 3111-6.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 3111-3116
    • Whiley, D.M.1    Limnios, E.A.2    Ray, S.3
  • 4
    • 77956565733 scopus 로고    scopus 로고
    • Molecular and structural analysis of mosaic variants of penicillin-binding protein 2 conferring decreased susceptibility to expanded-spectrum cephalosporins in Neisseria gonorrhoeae: role of epistatic mutations
    • Tomberg J, Unemo M, Davies C et al. Molecular and structural analysis of mosaic variants of penicillin-binding protein 2 conferring decreased susceptibility to expanded-spectrum cephalosporins in Neisseria gonorrhoeae: role of epistatic mutations. Biochemistry 2010; 49: 8062-70.
    • (2010) Biochemistry , vol.49 , pp. 8062-8070
    • Tomberg, J.1    Unemo, M.2    Davies, C.3
  • 5
    • 23844463837 scopus 로고    scopus 로고
    • The penC mutation conferring antibiotic resistance in Neisseria gonorrhoeae arises from a mutation in the PilQ secretin that interferes with multimer stability
    • Zhao S, Tobiason DM, Hu M et al. The penC mutation conferring antibiotic resistance in Neisseria gonorrhoeae arises from a mutation in the PilQ secretin that interferes with multimer stability. Mol Microbiol 2005; 57: 1238-51.
    • (2005) Mol Microbiol , vol.57 , pp. 1238-1251
    • Zhao, S.1    Tobiason, D.M.2    Hu, M.3
  • 6
    • 1642581491 scopus 로고    scopus 로고
    • A mutant form of the Neisseria gonorrhoeae pilus secretin protein PilQ allows increased entry of heme and antimicrobial compounds
    • Chen CJ, Tobiason DM, Thomas CE et al. A mutant form of the Neisseria gonorrhoeae pilus secretin protein PilQ allows increased entry of heme and antimicrobial compounds. J Bacteriol 2004; 186: 730-9.
    • (2004) J Bacteriol , vol.186 , pp. 730-739
    • Chen, C.J.1    Tobiason, D.M.2    Thomas, C.E.3
  • 7
    • 0029024772 scopus 로고
    • The sensitivity of 173 Sydney isolates of Neisseria gonorrhoeae to cefpodoxime and other antibiotics used to treat gonorrhoea
    • Tapsall JW, Phillips EA. The sensitivity of 173 Sydney isolates of Neisseria gonorrhoeae to cefpodoxime and other antibiotics used to treat gonorrhoea. Pathology 1995; 27:64-6.
    • (1995) Pathology , vol.27 , pp. 64-66
    • Tapsall, J.W.1    Phillips, E.A.2
  • 8
    • 65749101194 scopus 로고    scopus 로고
    • Phenotypic and genetic characterization of the 2008 WHO Neisseria gonorrhoeae reference strain panel intended for global quality assurance and quality control of gonococcal antimicrobial resistance surveillance for public health purposes
    • Unemo M, Fasth O, Fredlund H et al. Phenotypic and genetic characterization of the 2008 WHO Neisseria gonorrhoeae reference strain panel intended for global quality assurance and quality control of gonococcal antimicrobial resistance surveillance for public health purposes. J Antimicrob Chemother 2009; 63: 1142-51.
    • (2009) J Antimicrob Chemother , vol.63 , pp. 1142-1151
    • Unemo, M.1    Fasth, O.2    Fredlund, H.3
  • 9
    • 70349349063 scopus 로고    scopus 로고
    • Simple, rapid, and inexpensive detection of Neisseria gonorrhoeae resistance mechanisms using heat-denatured isolates and SYBR green-based real-time PCR
    • Kugelman G, Tapsall JW, Goire N et al. Simple, rapid, and inexpensive detection of Neisseria gonorrhoeae resistance mechanisms using heat-denatured isolates and SYBR green-based real-time PCR. Antimicrob Agents Chemother 2009; 53: 4211-6.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 4211-4216
    • Kugelman, G.1    Tapsall, J.W.2    Goire, N.3
  • 10
    • 34247850883 scopus 로고    scopus 로고
    • pilQ missense mutations have diverse effects on PilQ multimer formation, piliation, and pilus function in Neisseria gonorrhoeae
    • Helm RA, Barnhart MM, Seifert HS. pilQ missense mutations have diverse effects on PilQ multimer formation, piliation, and pilus function in Neisseria gonorrhoeae. J Bacteriol 2007; 189: 3198-207.
    • (2007) J Bacteriol , vol.189 , pp. 3198-3207
    • Helm, R.A.1    Barnhart, M.M.2    Seifert, H.S.3
  • 11
    • 0035050277 scopus 로고    scopus 로고
    • Antigenic variation of gonococcal pilin expression in vivo: analysis of the strain FA1090 pilin repertoire and identification of the pilS gene copies recombining with pilE during experimental human infection
    • Hamrick TS, Dempsey JA, Cohen MS et al. Antigenic variation of gonococcal pilin expression in vivo: analysis of the strain FA1090 pilin repertoire and identification of the pilS gene copies recombining with pilE during experimental human infection. Microbiology 2001; 147: 839-49.
    • (2001) Microbiology , vol.147 , pp. 839-849
    • Hamrick, T.S.1    Dempsey, J.A.2    Cohen, M.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.