-
1
-
-
33847640493
-
Immunosenescence: Emerging challenges for an ageing population
-
PMID:17313487
-
Aw D, Silva AB, Palmer DB. Immunosenescence: emerging challenges for an ageing population. Immunology 2007; 120:435-46; PMID:17313487; http://dx.doi.org/10.1111/j.1365-2567.2007.02555.x
-
(2007)
Immunology
, vol.120
, pp. 435-446
-
-
Aw, D.1
Silva, A.B.2
Palmer, D.B.3
-
3
-
-
84964246896
-
-
Aging NIO. Global Health and Aging Living Longer. NIH publication no. 11-7737. October 2011
-
Aging NIO. Global Health and Aging Living Longer. NIH publication no. 11-7737. October 2011. From: https://www.nia.nih.gov/research/publication/globalhealth-and-aging/preface
-
-
-
-
4
-
-
84876535364
-
Understanding immunosenescence to improve responses to vaccines
-
PMID:23598398
-
Goronzy JJ, Weyand CM. Understanding immunosenescence to improve responses to vaccines. Nature Immunol 2013; 14:428-36; PMID:23598398; http://dx.doi.org/10.1038/ni.2588
-
(2013)
Nature Immunol
, vol.14
, pp. 428-436
-
-
Goronzy, J.J.1
Weyand, C.M.2
-
5
-
-
84919767893
-
-
Fulop T, Franceschi C, Hirokawa K, Pawelec G, eds. Handbook on Immunosenescence: Springer Netherlands
-
Sebastián C, Lloberas J, Celada A. Molecular and Cellular Aspects of Macrophage Aging. In: Fulop T, Franceschi C, Hirokawa K, Pawelec G, eds. Handbook on Immunosenescence: Springer Netherlands, 2009:919-45
-
(2009)
Molecular and Cellular Aspects of Macrophage Aging
, pp. 919-945
-
-
Sebastián, C.1
Lloberas, J.2
Celada, A.3
-
6
-
-
0035754079
-
Cell senescence and cancer
-
PMID:11902575
-
Mathon NF, Lloyd AC. Cell senescence and cancer. Nat Rev Cancer 2001; 1:203-13; PMID:11902575; http://dx.doi.org/10.1038/35106045
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 203-213
-
-
Mathon, N.F.1
Lloyd, A.C.2
-
7
-
-
84874603171
-
Cellular senescence and the senescent secretory phenotype: Therapeutic opportunities
-
PMID:23454759
-
Tchkonia T, Zhu Y, van Deursen J, Campisi J, Kirkland JL. Cellular senescence and the senescent secretory phenotype: therapeutic opportunities. J Clin Invest 2013; 123:966-72; PMID:23454759; http://dx. doi.org/10.1172/JCI64098
-
(2013)
J Clin Invest
, vol.123
, pp. 966-972
-
-
Tchkonia, T.1
Zhu, Y.2
Van Deursen, J.3
Campisi, J.4
Kirkland, J.L.5
-
8
-
-
84925944989
-
Cellular senescence: From growth arrest to immunogenic conversion
-
PMID:25787341
-
Burton DG, Faragher RG. Cellular senescence: from growth arrest to immunogenic conversion. Age 2015; 37:27; PMID:25787341; http://dx.doi.org/10.1007/s11357-015-9764-2
-
(2015)
Age
, vol.37
, pp. 27
-
-
Burton, D.G.1
Faragher, R.G.2
-
9
-
-
33846111415
-
Inflammaging and anti-inflammaging: A systemic perspective on aging and longevity emerged from studies in humans
-
PMID:17116321
-
Franceschi C, Capri M, Monti D, Giunta S, Olivieri F, Sevini F, Panourgia MP, Invidia L, Celani L, Scurti M, et al. Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans. Mechanisms Age Dev 2007; 128:92-105; PMID:17116321; http://dx.doi.org/10.1016/j.mad.2006.11.016
-
(2007)
Mechanisms Age Dev
, vol.128
, pp. 92-105
-
-
Franceschi, C.1
Capri, M.2
Monti, D.3
Giunta, S.4
Olivieri, F.5
Sevini, F.6
Panourgia, M.P.7
Invidia, L.8
Celani, L.9
Scurti, M.10
-
10
-
-
80855138775
-
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
-
PMID:22048312
-
Baker DJ, Wijshake T, Tchkonia T, LeBrasseur NK, Childs BG, van de Sluis B, Kirkland JL, van Deursen JM. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature 2011; 479:232-6; PMID:22048312; http://dx.doi.org/10.1038/nature10600
-
(2011)
Nature
, vol.479
, pp. 232-236
-
-
Baker, D.J.1
Wijshake, T.2
Tchkonia, T.3
Lebrasseur, N.K.4
Childs, B.G.5
Van De Sluis, B.6
Kirkland, J.L.7
Van Deursen, J.M.8
-
11
-
-
84878864199
-
The hallmarks of aging
-
PMID:23746838
-
Lopez-Otin C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell 2013; 153:1194-217; PMID:23746838; http://dx.doi.org/10.1016/j.cell.2013.05.039
-
(2013)
Cell
, vol.153
, pp. 1194-1217
-
-
Lopez-Otin, C.1
Blasco, M.A.2
Partridge, L.3
Serrano, M.4
Kroemer, G.5
-
12
-
-
84900988267
-
Chronic inflammation (Inflammaging) and its potential contribution to ageassociated diseases
-
PMID:24833586
-
Franceschi C, Campisi J. Chronic inflammation (inflammaging) and its potential contribution to ageassociated diseases. J Gerontol Series A, Biol Sci Med Sci 2014; 69 Suppl 1:S4-9; PMID:24833586; http://dx.doi.org/10.1093/gerona/glu057
-
(2014)
J Gerontol Series A, Biol Sci Med Sci
, vol.69
, Issue.1
, pp. S4-S9
-
-
Franceschi, C.1
Campisi, J.2
-
13
-
-
84921436015
-
Premature immunosenescence is associated with memory dysfunction in rheumatoid arthritis
-
PMID:24751698
-
Petersen LE, Grassi-Oliveira R, Siara T, Dos Santos SG, Ilha M, de Nardi T, Keisermann M, Bauer ME. Premature immunosenescence is associated with memory dysfunction in rheumatoid arthritis. Neuroimmunomodulation 2015; 22:130-7; PMID:24751698; http://dx.doi.org/10.1159/000358437
-
(2015)
Neuroimmunomodulation
, vol.22
, pp. 130-137
-
-
Petersen, L.E.1
Grassi-Oliveira, R.2
Siara, T.3
Dos Santos, S.G.4
Ilha, M.5
De Nardi, T.6
Keisermann, M.7
Bauer, M.E.8
-
14
-
-
79551614790
-
HIV infection, inflammation, immunosenescence, and aging
-
PMID:21090961
-
Deeks SG. HIV infection, inflammation, immunosenescence, and aging. Ann Rev Med 2011; 62:141-55; PMID:21090961; http://dx.doi.org/10.1146/annurevmed-042909-093756
-
(2011)
Ann Rev Med
, vol.62
, pp. 141-155
-
-
Deeks, S.G.1
-
15
-
-
84884695279
-
Telomere dynamics in mice and humans
-
PMID:23956466
-
Calado RT, Dumitriu B. Telomere dynamics in mice and humans. Seminars Hematol 2013; 50:165-74; PMID:23956466; http://dx.doi.org/10.1053/j.seminhematol.2013.03.030
-
(2013)
Seminars Hematol
, vol.50
, pp. 165-174
-
-
Calado, R.T.1
Dumitriu, B.2
-
16
-
-
0035795985
-
An overview of the immune system
-
PMID:11403834
-
Parkin J, Cohen B. An overview of the immune system. Lancet 2001; 357:1777-89; PMID:11403834; http://dx.doi.org/10.1016/S0140-6736(00)04904-7
-
(2001)
Lancet
, vol.357
, pp. 1777-1789
-
-
Parkin, J.1
Cohen, B.2
-
18
-
-
0033562357
-
Dynamic changes in mouse hematopoietic stem cell numbers during aging
-
PMID:10233881
-
de Haan G, Van Zant G. Dynamic changes in mouse hematopoietic stem cell numbers during aging. Blood 1999; 93:3294-301; PMID:10233881
-
(1999)
Blood
, vol.93
, pp. 3294-3301
-
-
De Haan, G.1
Van Zant, G.2
-
19
-
-
79952338609
-
Accumulation of DNA damage in hematopoietic stem and progenitor cells during human aging
-
PMID:21408175
-
Rube CE, Fricke A, Widmann TA, Furst T, Madry H, Pfreundschuh M, Rube C. Accumulation of DNA damage in hematopoietic stem and progenitor cells during human aging. PloS One 2011; 6:e17487; PMID:21408175
-
(2011)
Plos One
, pp. 6
-
-
Rube, C.E.1
Fricke, A.2
Widmann, T.A.3
Furst, T.4
Madry, H.5
Pfreundschuh, M.6
Rube, C.7
-
20
-
-
84055200841
-
Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age
-
Pang WW, Price EA, Sahoo D, Beerman I, Maloney WJ, Rossi DJ, Schrier SL, Weissman IL. Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age. Proc Natl Acad Sci USA 2011; 108:20012-7
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 20012-20017
-
-
Pang, W.W.1
Price, E.A.2
Sahoo, D.3
Beerman, I.4
Maloney, W.J.5
Rossi, D.J.6
Schrier, S.L.7
Weissman, I.L.8
-
21
-
-
80355131976
-
Protective and pathogenic functions of macrophage subsets
-
PMID:21997792
-
Murray PJ, Wynn TA. Protective and pathogenic functions of macrophage subsets. Nat Rev Immunol 2011; 11:723-37; PMID:21997792; http://dx.doi.org/10.1038/nri3073
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 723-737
-
-
Murray, P.J.1
Wynn, T.A.2
-
22
-
-
56749174940
-
Exploring the full spectrum of macrophage activation
-
PMID:19029990
-
Mosser DM, Edwards JP. Exploring the full spectrum of macrophage activation. Nat Rev Immunol 2008; 8:958-69; PMID:19029990; http://dx.doi.org/10.1038/nri2448
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 958-969
-
-
Mosser, D.M.1
Edwards, J.P.2
-
23
-
-
13844301899
-
Innate immunity in aging: Impact on macrophage function
-
PMID:15268749
-
Plowden J, Renshaw-Hoelscher M, Engleman C, Katz J, Sambhara S. Innate immunity in aging: impact on macrophage function. Aging cell 2004; 3:161-7; PMID:15268749; http://dx.doi.org/10.1111/ j.1474-9728.2004.00102.x
-
(2004)
Aging Cell
, vol.3
, pp. 161-167
-
-
Plowden, J.1
Renshaw-Hoelscher, M.2
Engleman, C.3
Katz, J.4
Sambhara, S.5
-
24
-
-
0022373393
-
Monocyte chemiluminescence and macrophage precursors in the aged
-
PMID:4091040
-
Takahashi I, Ohmoto E, Aoyama S, Takizawa M, Oda Y, Nonaka K, Nakada H, Yorimitsu S, Kimura I. Monocyte chemiluminescence and macrophage precursors in the aged. Acta medica Okayama 1985; 39:447-51; PMID:4091040
-
(1985)
Acta Medica Okayama
, vol.39
, pp. 447-451
-
-
Takahashi, I.1
Ohmoto, E.2
Aoyama, S.3
Takizawa, M.4
Oda, Y.5
Nonaka, K.6
Nakada, H.7
Yorimitsu, S.8
Kimura, I.9
-
25
-
-
0021332894
-
The effect of aging and chronic sun exposure on human Langerhans cell populations
-
PMID:6199432
-
Thiers BH, Maize JC, Spicer SS, Cantor AB. The effect of aging and chronic sun exposure on human Langerhans cell populations. J Invest Dermatol 1984; 82:223-6; PMID:6199432; http://dx.doi.org/10.1111/1523-1747.ep12260055
-
(1984)
J Invest Dermatol
, vol.82
, pp. 223-226
-
-
Thiers, B.H.1
Maize, J.C.2
Spicer, S.S.3
Cantor, A.B.4
-
26
-
-
84930342642
-
Increases of M2a macrophages and fibrosis in aging muscle are influenced by bone marrow aging and negatively regulated by muscle-derived nitric oxide
-
PMID:26009878
-
Wang Y, Wehling-Henricks M, Samengo G, Tidball JG. Increases of M2a macrophages and fibrosis in aging muscle are influenced by bone marrow aging and negatively regulated by muscle-derived nitric oxide. Aging Cell 2015; 14:678-88; PMID:26009878; http://dx.doi.org/10.1111/acel.12350
-
(2015)
Aging Cell
, vol.14
, pp. 678-688
-
-
Wang, Y.1
Wehling-Henricks, M.2
Samengo, G.3
Tidball, J.G.4
-
27
-
-
0032617861
-
Agerelated decrease in accessory cell function of human alveolar macrophages
-
PMID:10071481
-
Zissel G, Schlaak M, Muller-Quernheim J. Agerelated decrease in accessory cell function of human alveolar macrophages. J Investig Med 1999; 47:51-6; PMID:10071481
-
(1999)
J Investig Med
, vol.47
, pp. 51-56
-
-
Zissel, G.1
Schlaak, M.2
Muller-Quernheim, J.3
-
28
-
-
0037012020
-
Immunosenescence of macrophages: Reduced MHC class II gene expression
-
PMID:11772525
-
Herrero C, Sebastian C, Marques L, Comalada M, Xaus J, Valledor AF, Lloberas J, Celada A. Immunosenescence of macrophages: reduced MHC class II gene expression. Exp Gerontol 2002; 37:389-94; PMID:11772525; http://dx.doi.org/10.1016/S0531-5565(01)00205-4
-
(2002)
Exp Gerontol
, vol.37
, pp. 389-394
-
-
Herrero, C.1
Sebastian, C.2
Marques, L.3
Comalada, M.4
Xaus, J.5
Valledor, A.F.6
Lloberas, J.7
Celada, A.8
-
29
-
-
0034855409
-
Evaluation of phagocytosis and arachidonate metabolism by alveolar macrophages and recruited neutrophils from F344xBN rats of different ages
-
PMID:11557288
-
Mancuso P, McNish RW, Peters-Golden M, Brock TG. Evaluation of phagocytosis and arachidonate metabolism by alveolar macrophages and recruited neutrophils from F344xBN rats of different ages. Mechanisms Ageing Dev 2001; 122:1899-913; PMID:11557288; http://dx.doi.org/10.1016/S0047-6374(01)00322-0
-
(2001)
Mechanisms Ageing Dev
, vol.122
, pp. 1899-1913
-
-
Mancuso, P.1
McNish, R.W.2
Peters-Golden, M.3
Brock, T.G.4
-
30
-
-
0035725929
-
Agerelated alterations in the inflammatory response to dermal injury
-
PMID:11710909
-
Swift ME, Burns AL, Gray KL, DiPietro LA. Agerelated alterations in the inflammatory response to dermal injury. J Invest Dermatol 2001; 117:1027-35; PMID:11710909; http://dx.doi.org/10.1046/j.0022-202x.2001.01539.x
-
(2001)
J Invest Dermatol
, vol.117
, pp. 1027-1035
-
-
Swift, M.E.1
Burns, A.L.2
Gray, K.L.3
Dipietro, L.A.4
-
31
-
-
0029995022
-
Nitric oxide and superoxide anion production decrease with age in resident and activated rat peritoneal macrophages
-
PMID:8612288
-
Alvarez E, Machado A, Sobrino F, Santa Maria C. Nitric oxide and superoxide anion production decrease with age in resident and activated rat peritoneal macrophages. Cell Immunol 1996; 169:152-5; PMID:8612288; http://dx.doi.org/10.1006/cimm.1996.0103
-
(1996)
Cell Immunol
, vol.169
, pp. 152-155
-
-
Alvarez, E.1
Machado, A.2
Sobrino, F.3
Santa Maria, C.4
-
32
-
-
0021871082
-
Changes in the macrophage function with aging. Comparative Biochem Physiol A
-
PMID:2863082
-
De La Fuente M. Changes in the macrophage function with aging. Comparative Biochem Physiol A, Comparative Physiol 1985; 81:935-8; PMID:2863082; http://dx.doi.org/10.1016/0300-9629(85)90933-8
-
(1985)
Comparative Physiol
, vol.81
, pp. 935-938
-
-
De La Fuente, M.1
-
33
-
-
0030319530
-
Effect of aging on the tumoricidal functions of murine peritoneal macrophages
-
PMID:9523280
-
Khare V, Sodhi A, Singh SM. Effect of aging on the tumoricidal functions of murine peritoneal macrophages. Natural Immunity 1996; 15:285-94; PMID:9523280
-
(1996)
Natural Immunity
, vol.15
, pp. 285-294
-
-
Khare, V.1
Sodhi, A.2
Singh, S.M.3
-
34
-
-
0034665085
-
Effect of aging on the modulation of macrophage functions by neuropeptides
-
PMID:11057762
-
De la Fuente M, Medina S, Del Rio M, Ferrandez MD, Hernanz A. Effect of aging on the modulation of macrophage functions by neuropeptides. Life Sci 2000; 67:2125-35; PMID:11057762; http://dx.doi.org/10.1016/S0024-3205(00)00799-2
-
(2000)
Life Sci
, vol.67
, pp. 2125-2135
-
-
De La Fuente, M.1
Medina, S.2
Del Rio, M.3
Ferrandez, M.D.4
Hernanz, A.5
-
35
-
-
0027161033
-
Interleukin-6 and aging: Blood levels and mononuclear cell production increase with advancing age and in vitro production is modifiable by dietary restriction
-
PMID:8218595
-
Ershler WB, Sun WH, Binkley N, Gravenstein S, Volk MJ, Kamoske G, Klopp RG, Roecker EB, Daynes RA, Weindruch R. Interleukin-6 and aging: blood levels and mononuclear cell production increase with advancing age and in vitro production is modifiable by dietary restriction. Lymphokine Cytokine Res 1993; 12:225-30; PMID:8218595
-
(1993)
Lymphokine Cytokine Res
, vol.12
, pp. 225-230
-
-
Ershler, W.B.1
Sun, W.H.2
Binkley, N.3
Gravenstein, S.4
Volk, M.J.5
Kamoske, G.6
Klopp, R.G.7
Roecker, E.B.8
Daynes, R.A.9
Weindruch, R.10
-
36
-
-
0037011794
-
RANTES and MIP-1alpha production by T lymphocytes, monocytes and NK cells from nonagenarian subjects
-
PMID:11772507
-
Mariani E, Pulsatelli L, Neri S, Dolzani P, Meneghetti A, Silvestri T, Ravaglia G, Forti P, Cattini L, Facchini A. RANTES and MIP-1alpha production by T lymphocytes, monocytes and NK cells from nonagenarian subjects. Exp Gerontol 2002; 37:219-26; PMID:11772507; http://dx.doi.org/10.1016/S0531-5565(01)00187-5
-
(2002)
Exp Gerontol
, vol.37
, pp. 219-226
-
-
Mariani, E.1
Pulsatelli, L.2
Neri, S.3
Dolzani, P.4
Meneghetti, A.5
Silvestri, T.6
Ravaglia, G.7
Forti, P.8
Cattini, L.9
Facchini, A.10
-
37
-
-
0029737506
-
Lower serum concentrations of cytokines in elderly patients with pneumonia and the impaired production of cytokines by peripheral blood monocytes in the elderly
-
PMID:8870709
-
Gon Y, Hashimoto S, Hayashi S, Koura T, Matsumoto K, Horie T. Lower serum concentrations of cytokines in elderly patients with pneumonia and the impaired production of cytokines by peripheral blood monocytes in the elderly. Clin Exp Immunol 1996; 106:120-6; PMID:8870709
-
(1996)
Clin Exp Immunol
, vol.106
, pp. 120-126
-
-
Gon, Y.1
Hashimoto, S.2
Hayashi, S.3
Koura, T.4
Matsumoto, K.5
Horie, T.6
-
38
-
-
0035140821
-
Interleukin-6 production does not increase with age
-
PMID:11213271
-
Beharka AA, Meydani M, Wu D, Leka LS, Meydani A, Meydani SN. Interleukin-6 production does not increase with age. J Gerontol Series A, Biological Sci Med Sci 2001; 56:B81-8; PMID:11213271; http://dx.doi.org/10.1093/gerona/56.2.B81
-
(2001)
J Gerontol Series A, Biological Sci Med Sci
, vol.56
, pp. B81-B88
-
-
Beharka, A.A.1
Meydani, M.2
Wu, D.3
Leka, L.S.4
Meydani, A.5
Meydani, S.N.6
-
39
-
-
0034955930
-
Cytokine production by stimulated mononuclear cells did not change with aging in apparently healthy, well-nourished women
-
PMID:11438118
-
Ahluwalia N, Mastro AM, Ball R, Miles MP, Rajendra R, Handte G. Cytokine production by stimulated mononuclear cells did not change with aging in apparently healthy, well-nourished women. Mechanisms Ageing Dev 2001; 122:1269-79; PMID:11438118; http://dx.doi.org/10.1016/S0047-6374(01)00266-4
-
(2001)
Mechanisms Ageing Dev
, vol.122
, pp. 1269-1279
-
-
Ahluwalia, N.1
Mastro, A.M.2
Ball, R.3
Miles, M.P.4
Rajendra, R.5
Handte, G.6
-
40
-
-
0031227764
-
Enhanced expression of inducible cyclooxygenase with age in murine macrophages
-
Hayek MG, Mura C, Wu D, Beharka AA, Han SN, Paulson KE, Hwang D, Meydani SN. Enhanced expression of inducible cyclooxygenase with age in murine macrophages. J Immunol 1997; 159:2445-51
-
(1997)
J Immunol
, vol.159
, pp. 2445-2451
-
-
Hayek, M.G.1
Mura, C.2
Wu, D.3
Beharka, A.A.4
Han, S.N.5
Paulson, K.E.6
Hwang, D.7
Meydani, S.N.8
-
41
-
-
4344595492
-
Mechanism of age-associated up-regulation in macrophage PGE2 synthesis. Brain, Behavior
-
PMID:15331118
-
Wu D, Meydani SN. Mechanism of age-associated up-regulation in macrophage PGE2 synthesis. Brain, Behavior, Immunity 2004; 18:487-94; PMID:15331118; http://dx.doi.org/10.1016/j.bbi.2004.05.003
-
(2004)
Immunity
, vol.18
, pp. 487-494
-
-
Wu, D.1
Meydani, S.N.2
-
42
-
-
0036838909
-
Cutting edge: Impaired Toll-like receptor expression and function in aging
-
Renshaw M, Rockwell J, Engleman C, Gewirtz A, Katz J, Sambhara S. Cutting edge: impaired Toll-like receptor expression and function in aging. J Immunol 2002; 169:4697-701; http://dx.doi.org/10.4049/jimmunol.169.9.4697
-
(2002)
J Immunol
, vol.169
, pp. 4697-4701
-
-
Renshaw, M.1
Rockwell, J.2
Engleman, C.3
Gewirtz, A.4
Katz, J.5
Sambhara, S.6
-
43
-
-
0041343131
-
Ageing and wound healing
-
PMID:12510172
-
Ashcroft GS, Mills SJ, Ashworth JJ. Ageing and wound healing. Biogerontology 2002; 3:337-45; PMID:12510172; http://dx.doi.org/10.1023/A:1021399228395
-
(2002)
Biogerontology
, vol.3
, pp. 337-345
-
-
Ashcroft, G.S.1
Mills, S.J.2
Ashworth, J.J.3
-
44
-
-
0031931635
-
Aging alters the inflammatory and endothelial cell adhesion molecule profiles during human cutaneous wound healing
-
PMID:9461121
-
Ashcroft GS, Horan MA, Ferguson MW. Aging alters the inflammatory and endothelial cell adhesion molecule profiles during human cutaneous wound healing. Lab Invest; J Tech Meth Pathol 1998; 78:47-58; PMID:9461121
-
(1998)
Lab Invest
, vol.78
, pp. 47-58
-
-
Ashcroft, G.S.1
Horan, M.A.2
Ferguson, M.W.3
-
45
-
-
0342289468
-
Promotion of wound repair in old mice by local injection of macrophages
-
Danon D, Kowatch MA, Roth GS. Promotion of wound repair in old mice by local injection of macrophages. Proc Natl Acad Sci USA 1989; 86:2018-20
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 2018-2020
-
-
Danon, D.1
Kowatch, M.A.2
Roth, G.S.3
-
46
-
-
0041343279
-
An angiogenic switch in macrophages involving synergy between Toll-like receptors 2, 4, 7, and 9 and adenosine A(2A) receptors
-
PMID:12875990
-
Pinhal-Enfield G, Ramanathan M, Hasko G, Vogel SN, Salzman AL, Boons GJ, Leibovich SJ. An angiogenic switch in macrophages involving synergy between Toll-like receptors 2, 4, 7, and 9 and adenosine A(2A) receptors. Am J Pathol 2003; 163:711-21; PMID:12875990; http://dx.doi.org/10.1016/S0002-9440(10)63698-X
-
(2003)
Am J Pathol
, vol.163
, pp. 711-721
-
-
Pinhal-Enfield, G.1
Ramanathan, M.2
Hasko, G.3
Vogel, S.N.4
Salzman, A.L.5
Boons, G.J.6
Leibovich, S.J.7
-
47
-
-
80053516103
-
Functional CD8 T cell memory responding to persistent latent infection is maintained for life
-
Lang A, Nikolich-Zugich J. Functional CD8 T cell memory responding to persistent latent infection is maintained for life. J Immunol 2011; 187:3759-68; http://dx.doi.org/10.4049/jimmunol.1100666
-
(2011)
J Immunol
, vol.187
, pp. 3759-3768
-
-
Lang, A.1
Nikolich-Zugich, J.2
-
48
-
-
84857416171
-
Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans
-
PMID:22365666
-
den Braber I, Mugwagwa T, Vrisekoop N, Westera L, Mogling R, de Boer AB, Willems N, Schrijver EH, Spierenburg G, Gaiser K, et al. Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans. Immunity 2012; 36:288-97; PMID:22365666; http://dx.doi.org/10.1016/j.immuni.2012.02.006
-
(2012)
Immunity
, vol.36
, pp. 288-297
-
-
Den Braber, I.1
Mugwagwa, T.2
Vrisekoop, N.3
Westera, L.4
Mogling, R.5
De Boer, A.B.6
Willems, N.7
Schrijver, E.H.8
Spierenburg, G.9
Gaiser, K.10
-
49
-
-
84874199537
-
Thymus Size and Age-related Thymic Involution: Early Programming, Sexual Dimorphism, Progenitors and Stroma
-
PMID:22724086
-
Gui J, Mustachio LM, Su DM, Craig RW. Thymus Size and Age-related Thymic Involution: Early Programming, Sexual Dimorphism, Progenitors and Stroma. Aging Dis 2012; 3:280-90; PMID:22724086
-
(2012)
Aging Dis
, vol.3
, pp. 280-290
-
-
Gui, J.1
Mustachio, L.M.2
Su, D.M.3
Craig, R.W.4
-
50
-
-
0022377731
-
The involution of the ageing human thymic epithelium is independent of puberty. A morphometric study
-
PMID:4081647
-
Steinmann GG, Klaus B, Muller-Hermelink HK. The involution of the ageing human thymic epithelium is independent of puberty. A morphometric study. Scandinavian J Immunol 1985; 22:563-75; PMID:4081647; http://dx.doi.org/10.1111/j.1365-3083.1985.tb01916.x
-
(1985)
Scandinavian J Immunol
, vol.22
, pp. 563-575
-
-
Steinmann, G.G.1
Klaus, B.2
Muller-Hermelink, H.K.3
-
51
-
-
80052375962
-
The narrowing of the CD8 T cell repertoire in old age
-
PMID:21652194
-
Blackman MA, Woodland DL. The narrowing of the CD8 T cell repertoire in old age. Curr Opin Immunol 2011; 23:537-42; PMID:21652194; http://dx.doi.org/10.1016/j.coi.2011.05.005
-
(2011)
Curr Opin Immunol
, vol.23
, pp. 537-542
-
-
Blackman, M.A.1
Woodland, D.L.2
-
52
-
-
67649407892
-
CD28(-) T cells: Their role in the age-associated decline of immune function
-
PMID:19540809
-
Weng NP, Akbar AN, Goronzy J. CD28(-) T cells: their role in the age-associated decline of immune function. Trends Immunol 2009; 30:306-12; PMID:19540809; http://dx.doi.org/10.1016/j.it.2009.03.013
-
(2009)
Trends Immunol
, vol.30
, pp. 306-312
-
-
Weng, N.P.1
Akbar, A.N.2
Goronzy, J.3
-
53
-
-
5644299299
-
Cellular cholesterol enrichment impairs T cell activation and chemotaxis
-
PMID:15491683
-
Nguyen DH, Espinoza JC, Taub DD. Cellular cholesterol enrichment impairs T cell activation and chemotaxis. Mechan Ageing Dev 2004; 125:641-50; PMID:15491683; http://dx.doi.org/10.1016/j.mad.2004.08.002
-
(2004)
Mechan Ageing Dev
, vol.125
, pp. 641-650
-
-
Nguyen, D.H.1
Espinoza, J.C.2
Taub, D.D.3
-
54
-
-
0033523712
-
Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice
-
PMID:10510091
-
Haynes L, Linton PJ, Eaton SM, Tonkonogy SL, Swain SL. Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice. J Exp Med 1999; 190:1013-24; PMID:10510091; http://dx.doi.org/10.1084/jem.190.7.1013
-
(1999)
J Exp Med
, vol.190
, pp. 1013-1024
-
-
Haynes, L.1
Linton, P.J.2
Eaton, S.M.3
Tonkonogy, S.L.4
Swain, S.L.5
-
55
-
-
84870293512
-
Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity
-
PMID:23023500
-
Li G, Yu M, Lee WW, Tsang M, Krishnan E, Weyand CM, Goronzy JJ. Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity. Nat Med 2012; 18:1518-24; PMID:23023500; http://dx.doi.org/10.1038/nm.2963
-
(2012)
Nat Med
, vol.18
, pp. 1518-1524
-
-
Li, G.1
Yu, M.2
Lee, W.W.3
Tsang, M.4
Krishnan, E.5
Weyand, C.M.6
Goronzy, J.J.7
-
56
-
-
84871835297
-
Peripheral selection rather than thymic involution explains sudden contraction in naive CD4 T-cell diversity with age
-
Johnson PL, Yates AJ, Goronzy JJ, Antia R. Peripheral selection rather than thymic involution explains sudden contraction in naive CD4 T-cell diversity with age. Proc Natl Acad Sci U S A 2012; 109:21432-7
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 21432-21437
-
-
Johnson, P.L.1
Yates, A.J.2
Goronzy, J.J.3
Antia, R.4
-
57
-
-
84868199335
-
Age-related changes in CD8 T cell homeostasis and immunity to infection
-
PMID:22554418
-
Nikolich-Zugich J, Li G, Uhrlaub JL, Renkema KR, Smithey MJ. Age-related changes in CD8 T cell homeostasis and immunity to infection. Seminars Immunol 2012; 24:356-64; PMID:22554418; http://dx.doi.org/10.1016/j.smim.2012.04.009
-
(2012)
Seminars Immunol
, vol.24
, pp. 356-364
-
-
Nikolich-Zugich, J.1
Li, G.2
Uhrlaub, J.L.3
Renkema, K.R.4
Smithey, M.J.5
-
58
-
-
84868198678
-
Age-related Deficiencies in Antigen-Specific CD4 T cell Responses: Lessons from Mouse Models
-
PMID:22396889
-
Haynes L, Lefebvre JS. Age-related Deficiencies in Antigen-Specific CD4 T cell Responses: Lessons from Mouse Models. Aging Dis 2011; 2:374-81; PMID:22396889
-
(2011)
Aging Dis
, vol.2
, pp. 374-381
-
-
Haynes, L.1
Lefebvre, J.S.2
-
59
-
-
0035915757
-
Age-related change in peripheral blood T-lymphocyte subpopulations and cytomegalovirus infection in the very old: The Swedish longitudinal OCTO immune study
-
PMID:11164473
-
Olsson J, Wikby A, Johansson B, Lofgren S, Nilsson BO, Ferguson FG. Age-related change in peripheral blood T-lymphocyte subpopulations and cytomegalovirus infection in the very old: the Swedish longitudinal OCTO immune study. Mechan Age Dev 2000; 121:187-201; PMID:11164473; http://dx.doi.org/10.1016/S0047-6374(00)00210-4
-
(2000)
Mechan Age Dev
, vol.121
, pp. 187-201
-
-
Olsson, J.1
Wikby, A.2
Johansson, B.3
Lofgren, S.4
Nilsson, B.O.5
Ferguson, F.G.6
-
60
-
-
0037012021
-
Expansions of peripheral blood CD8 T-lymphocyte subpopulations and an association with cytomegalovirus seropositivity in the elderly: The Swedish NONA immune study
-
PMID:11772532
-
Wikby A, Johansson B, Olsson J, Lofgren S, Nilsson BO, Ferguson F. Expansions of peripheral blood CD8 T-lymphocyte subpopulations and an association with cytomegalovirus seropositivity in the elderly: the Swedish NONA immune study. Exp Gerontol 2002; 37:445-53; PMID:11772532; http://dx.doi.org/10.1016/S0531-5565(01)00212-1
-
(2002)
Exp Gerontol
, vol.37
, pp. 445-453
-
-
Wikby, A.1
Johansson, B.2
Olsson, J.3
Lofgren, S.4
Nilsson, B.O.5
Ferguson, F.6
-
61
-
-
84964201452
-
-
Center for Disease Control and Prevention. Cytomegalovirus (CMV) and Congenital CMV Infection: Prevention. 28 July 2010 From
-
Center for Disease Control and Prevention. Cytomegalovirus (CMV) and Congenital CMV Infection: Prevention. 28 July 2010 From: http://www.cdc.gov/cmv/prevention.html
-
-
-
-
62
-
-
80455144472
-
Rejuvenating senescent and centenarian human cells by reprogramming through the pluripotent state
-
PMID:22056670
-
Lapasset L, Milhavet O, Prieur A, Besnard E, Babled A, Ait-Hamou N, Leschik J, Pellestor F, Ramirez JM, De Vos J, et al. Rejuvenating senescent and centenarian human cells by reprogramming through the pluripotent state. Genes Dev 2011; 25:2248-53; PMID:22056670; http://dx.doi.org/10.1101/gad.173922.111
-
(2011)
Genes Dev
, vol.25
, pp. 2248-2253
-
-
Lapasset, L.1
Milhavet, O.2
Prieur, A.3
Besnard, E.4
Babled, A.5
Ait-Hamou, N.6
Leschik, J.7
Pellestor, F.8
Ramirez, J.M.9
De Vos, J.10
-
63
-
-
84879694584
-
Generation of engraftable hematopoietic stem cells from induced pluripotent stem cells by way of teratoma formation
-
PMID:23670574
-
Suzuki N, Yamazaki S, Yamaguchi T, Okabe M, Masaki H, Takaki S, Otsu M, Nakauchi H. Generation of engraftable hematopoietic stem cells from induced pluripotent stem cells by way of teratoma formation. Mol Therapy 2013; 21:1424-31; PMID:23670574; http://dx.doi.org/10.1038/mt.2013.71
-
(2013)
Mol Therapy
, vol.21
, pp. 1424-1431
-
-
Suzuki, N.1
Yamazaki, S.2
Yamaguchi, T.3
Okabe, M.4
Masaki, H.5
Takaki, S.6
Otsu, M.7
Nakauchi, H.8
-
64
-
-
80053606380
-
Impact of caloric and dietary restriction regimens on markers of health and longevity in humans and animals: A summary of available findings
-
PMID:21981968
-
Trepanowski JF, Canale RE, Marshall KE, Kabir MM, Bloomer RJ. Impact of caloric and dietary restriction regimens on markers of health and longevity in humans and animals: a summary of available findings. Nutri J 2011; 10:107; PMID:21981968; http://dx.doi.org/10.1186/1475-2891-10-107
-
(2011)
Nutri J
, vol.10
, pp. 107
-
-
Trepanowski, J.F.1
Canale, R.E.2
Marshall, K.E.3
Kabir, M.M.4
Bloomer, R.J.5
-
65
-
-
84937517237
-
Autophagy Controls Acquisition of Aging Features in Macrophages
-
PMID:25764971
-
Stranks AJ, Hansen AL, Panse I, Mortensen M, Ferguson DJ, Puleston DJ, Shenderov K, Watson AS, Veldhoen M, Phadwal K, et al. Autophagy Controls Acquisition of Aging Features in Macrophages. J Innate Immunity 2015; 7:375-91; PMID:25764971; http://dx.doi.org/10.1159/000370112
-
(2015)
J Innate Immunity
, vol.7
, pp. 375-391
-
-
Stranks, A.J.1
Hansen, A.L.2
Panse, I.3
Mortensen, M.4
Ferguson, D.J.5
Puleston, D.J.6
Shenderov, K.7
Watson, A.S.8
Veldhoen, M.9
Phadwal, K.10
-
66
-
-
5444232420
-
Age effects on macrophage function vary by tissue site, nature of stimulant, and exercise behavior
-
PMID:15489058
-
Kohut ML, Senchina DS, Madden KS, Martin AE, Felten DL, Moynihan JA. Age effects on macrophage function vary by tissue site, nature of stimulant, and exercise behavior. Exp Gerontol 2004; 39:1347-60; PMID:15489058; http://dx.doi.org/10.1016/j.exger.2004.07.001
-
(2004)
Exp Gerontol
, vol.39
, pp. 1347-1360
-
-
Kohut, M.L.1
Senchina, D.S.2
Madden, K.S.3
Martin, A.E.4
Felten, D.L.5
Moynihan, J.A.6
-
67
-
-
0029022703
-
Superoxide generation by alveolar macrophages from aged rats: Improvement by in vitro treatment with IFN-gamma
-
PMID:7564571
-
Hayakawa H, Sato A, Yagi T, Uchiyama H, Ide K, Nakano M. Superoxide generation by alveolar macrophages from aged rats: improvement by in vitro treatment with IFN-gamma. Mechan Ageing dev 1995; 80:199-211; PMID:7564571; http://dx.doi.org/10.1016/0047-6374(95)01573-I
-
(1995)
Mechan Ageing Dev
, vol.80
, pp. 199-211
-
-
Hayakawa, H.1
Sato, A.2
Yagi, T.3
Uchiyama, H.4
Ide, K.5
Nakano, M.6
-
68
-
-
0032968287
-
The immune-endocrine loop during aging: Role of growth hormone and insulin-like growth factor-I
-
PMID:9876236
-
Burgess W, Liu Q, Zhou J, Tang Q, Ozawa A, Van- Hoy R, Arkins S, Dantzer R, Kelley KW. The immune-endocrine loop during aging: role of growth hormone and insulin-like growth factor-I. Neuroimmunomodulation 1999; 6:56-68; PMID:9876236; http://dx.doi.org/10.1159/000026365
-
(1999)
Neuroimmunomodulation
, vol.6
, pp. 56-68
-
-
Burgess, W.1
Liu, Q.2
Zhou, J.3
Tang, Q.4
Ozawa, A.5
Van- Hoy, R.6
Arkins, S.7
Dantzer, R.8
Kelley, K.W.9
-
69
-
-
20344384993
-
Immunosenescence and macrophage functional plasticity: Dysregulation of macrophage function by age-associated microenvironmental changes
-
PMID:15882345
-
Stout RD, Suttles J. Immunosenescence and macrophage functional plasticity: dysregulation of macrophage function by age-associated microenvironmental changes. Immunol Rev 2005; 205:60-71; PMID:15882345; http://dx.doi.org/10.1111/j.0105-2896.2005.00260.x
-
(2005)
Immunol Rev
, vol.205
, pp. 60-71
-
-
Stout, R.D.1
Suttles, J.2
-
70
-
-
84877798009
-
Targeting macrophages rescues age-related immune deficiencies in C57BL/6J geriatric mice
-
PMID:23442123
-
Jackaman C, Radley-Crabb HG, Soffe Z, Shavlakadze T, Grounds MD, Nelson DJ. Targeting macrophages rescues age-related immune deficiencies in C57BL/6J geriatric mice. Aging Cell 2013; 12:345-57; PMID:23442123; http://dx.doi.org/10.1111/acel.12062
-
(2013)
Aging Cell
, vol.12
, pp. 345-357
-
-
Jackaman, C.1
Radley-Crabb, H.G.2
Soffe, Z.3
Shavlakadze, T.4
Grounds, M.D.5
Nelson, D.J.6
-
71
-
-
0030887804
-
Macrophage prostaglandin production contributes to the age-associated decrease in T cell function which is reversed by the dietary antioxidant vitamin
-
PMID:9089571
-
Beharka AA, Wu D, Han SN, Meydani SN. Macrophage prostaglandin production contributes to the age-associated decrease in T cell function which is reversed by the dietary antioxidant vitamin E. Mechan Ageing Dev 1997; 93:59-77; PMID:9089571; http://dx.doi.org/10.1016/S0047-6374(96)01819-2
-
(1997)
E. Mechan Ageing Dev
, vol.93
, pp. 59-77
-
-
Beharka, A.A.1
Wu, D.2
Han, S.N.3
Meydani, S.N.4
-
72
-
-
23844486206
-
Effects of castration on thymocyte development in two different models of thymic involution
-
Heng TS, Goldberg GL, Gray DH, Sutherland JS, Chidgey AP, Boyd RL. Effects of castration on thymocyte development in two different models of thymic involution. J Immunol 2005; 175:2982-93; http://dx.doi.org/10.4049/jimmunol.175.5.2982
-
(2005)
J Immunol
, vol.175
, pp. 2982-2993
-
-
Heng, T.S.1
Goldberg, G.L.2
Gray, D.H.3
Sutherland, J.S.4
Chidgey, A.P.5
Boyd, R.L.6
-
73
-
-
23444461765
-
Activation of thymic regeneration in mice and humans following androgen blockade
-
Sutherland JS, Goldberg GL, Hammett MV, Uldrich AP, Berzins SP, Heng TS, Blazar BR, Millar JL, Malin MA, Chidgey AP, et al. Activation of thymic regeneration in mice and humans following androgen blockade. J Immunol 2005; 175:2741-53; http://dx.doi.org/10.4049/jimmunol.175.4.2741
-
(2005)
J Immunol
, vol.175
, pp. 2741-2753
-
-
Sutherland, J.S.1
Goldberg, G.L.2
Hammett, M.V.3
Uldrich, A.P.4
Berzins, S.P.5
Heng, T.S.6
Blazar, B.R.7
Millar, J.L.8
Malin, M.A.9
Chidgey, A.P.10
-
74
-
-
0029794831
-
Enhancement of thymopoiesis after bone marrow transplant by in vivo interleukin-7
-
PMID:8781449
-
Bolotin E, Smogorzewska M, Smith S, Widmer M, Weinberg K. Enhancement of thymopoiesis after bone marrow transplant by in vivo interleukin-7. Blood 1996; 88:1887-94; PMID:8781449
-
(1996)
Blood
, vol.88
, pp. 1887-1894
-
-
Bolotin, E.1
Smogorzewska, M.2
Smith, S.3
Widmer, M.4
Weinberg, K.5
-
75
-
-
33646141172
-
T cell development, ageing and Interleukin-7
-
PMID:16529797
-
Aspinall R. T cell development, ageing and Interleukin-7. Mechan Ageing Dev 2006; 127:572-8; PMID:16529797; http://dx.doi.org/10.1016/j.mad.2006.01.016
-
(2006)
Mechan Ageing Dev
, vol.127
, pp. 572-578
-
-
Aspinall, R.1
-
76
-
-
8444234981
-
Thymic transplantation for complete DiGeorge syndrome: Medical and surgical considerations
-
PMID:15547821
-
Rice HE, Skinner MA, Mahaffey SM, Oldham KT, Ing RJ, Hale LP, Markert ML. Thymic transplantation for complete DiGeorge syndrome: medical and surgical considerations. J Pediatric Surg 2004; 39:1607-15; PMID:15547821; http://dx.doi.org/10.1016/j.jpedsurg.2004.07.020
-
(2004)
J Pediatric Surg
, vol.39
, pp. 1607-1615
-
-
Rice, H.E.1
Skinner, M.A.2
Mahaffey, S.M.3
Oldham, K.T.4
Ing, R.J.5
Hale, L.P.6
Markert, M.L.7
-
77
-
-
33745516115
-
Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium
-
PMID:16791197
-
Rossi SW, Jenkinson WE, Anderson G, Jenkinson EJ. Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium. Nature 2006; 441:988-91; PMID:16791197; http://dx.doi.org/10.1038/nature04813
-
(2006)
Nature
, vol.441
, pp. 988-991
-
-
Rossi, S.W.1
Jenkinson, W.E.2
Erson, G.3
Jenkinson, E.J.4
-
78
-
-
84930616180
-
Efficient in vitro generation of functional thymic epithelial progenitors from human embryonic stem cells
-
PMID:26044259
-
Su M, Hu R, Jin J, Yan Y, Song Y, Sullivan R, Lai L. Efficient in vitro generation of functional thymic epithelial progenitors from human embryonic stem cells. Scientific Reports 2015; 5:9882; PMID:26044259; http://dx.doi.org/10.1038/srep09882
-
(2015)
Scientific Reports
, vol.5
, pp. 9882
-
-
Su, M.1
Hu, R.2
Jin, J.3
Yan, Y.4
Song, Y.5
Sullivan, R.6
Lai, L.7
-
79
-
-
84867352260
-
The mouse lymph node as an ectopic transplantation site for multiple tissues
-
PMID:23000933
-
Komori J, Boone L, DeWard A, Hoppo T, Lagasse E. The mouse lymph node as an ectopic transplantation site for multiple tissues. Nat Biotechnol 2012; 30:976-83; PMID:23000933; http://dx.doi.org/10.1038/nbt.2379
-
(2012)
Nat Biotechnol
, vol.30
, pp. 976-983
-
-
Komori, J.1
Boone, L.2
Deward, A.3
Hoppo, T.4
Lagasse, E.5
|