Epigenetic assimilation in the aging human brain

Genome Biology

Volumn 17, Issue 1, 2016, Pages

  Oh, Gabriel ^a   Ebrahimi, Sasha ^a   Wang, Sun Chong ^b   Cortese, Rene ^a,c   Kaminsky, Zachary A ^d   Gottesman, Irving I ^e   Burke, James R ^f   Plassman, Brenda L ^f   Petronis, Art ^a  

^a CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^b NATIONAL CENTRAL UNIVERSITY   (Taiwan)

^c UNIVERSITY OF CHICAGO   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF MINNESOTA   (United States)

^f DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Aging; Alzheimer's disease; Dedifferentiation; DNA methylation; Epigenetic drift; Epigenetics; Genomic organization; Transcriptome

Indexed keywords

TRANSCRIPTOME;

ADULT; AGE; AGED; AGING; ALZHEIMER DISEASE; ARTICLE; BRAIN; CELL DEDIFFERENTIATION; CLINICAL ARTICLE; CORRELATIONAL STUDY; DNA DETERMINATION; DNA MODIFICATION; DNA TRANSCRIPTION; EPIGENETIC ASSIMILATION; EPIGENETICS; GENE ONTOLOGY; GENETIC VARIABILITY; HUMAN; HUMAN TISSUE; MOLECULAR DYNAMICS; RISK FACTOR; TRANSCRIPTOMICS; TWINS; DNA METHYLATION; FEMALE; FRONTAL LOBE; GENETIC EPIGENESIS; GENETICS; GROWTH, DEVELOPMENT AND AGING; MALE; METABOLISM; MIDDLE AGED; PHYSIOLOGY; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; FRONTAL LOBE; HUMANS; MALE; MIDDLE AGED; TWINS;

EID: 84964300307     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-016-0946-8     Document Type: Article

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