Hydroxysafflor yellow A protects neurons from excitotoxic death through inhibition of NMDARs

ASN Neuro

Volumn 8, Issue 2, 2016, Pages

  Wang, Xingtao ^a   Ma, Zhiyuan ^b   Fu, Zhongxiao ^c   Gao, Su ^a   Yang, Liu ^a   Jin, Yan ^c   Sun, Hui ^a   Wang, Chaoyun ^a   Fan, Weiming ^a   Chen, Lin ^c   Zheng, Qing Yin ^a   Bi, Guoqiang ^c   Ma, Chun Lei ^a  

^a BINZHOU MEDICAL UNIVERSITY   (China)

^b SHANGHAI UNIVERSITY OF FINANCE AND ECONOMICS   (China)

^c University of Science and Technology of China   (China)

Author keywords

Ca2+ imaging; Hydroxysafflor yellow A; NMDA receptor; Oxygen glucose deprivation; Whole cell patch clamp recording

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; HYDROXYSAFFLOR YELLOW A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PLANT MEDICINAL PRODUCT; SAFFLOWER EXTRACT; UNCLASSIFIED DRUG; YELLOW FLUORESCENT PROTEIN; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; AMINO ACID RECEPTOR AFFECTING AGENT; AMINO ACID RECEPTOR BLOCKING AGENT; CALCIUM; CENTRAL STIMULANT AGENT; CHALCONE; GLUCOSE; NEUROPROTECTIVE AGENT; PICROTOXIN; QUINONE DERIVATIVE; STRYCHNINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CELL DEATH; CELL MEMBRANE DEPOLARIZATION; CELL VIABILITY; CONTROLLED STUDY; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPAL NEURONAL CULTURE; IMAGE ANALYSIS; LONG TERM POTENTIATION; MOUSE; NEUROTRANSMITTER RELEASE; NONHUMAN; PATCH CLAMP TECHNIQUE; REPERFUSION INJURY; SAFFLOWER; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; CELL CULTURE; CYTOLOGY; DEFICIENCY; DRUG EFFECTS; HIPPOCAMPAL CA1 REGION; HYPOXIA; IN VITRO STUDY; MEMBRANE POTENTIAL; METABOLISM; NERVE CELL; NEWBORN;

6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ANIMALS; ANIMALS, NEWBORN; CA1 REGION, HIPPOCAMPAL; CALCIUM; CELL DEATH; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM STIMULANTS; CHALCONE; EXCITATORY AMINO ACID AGENTS; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; GLUCOSE; GLYCINE AGENTS; HYPOXIA; IN VITRO TECHNIQUES; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; NEURONS; NEUROPROTECTIVE AGENTS; PICROTOXIN; QUINONES; RECEPTORS, N-METHYL-D-ASPARTATE; STRYCHNINE;

EID: 84964284418     PISSN: None     EISSN: 17590914     Source Type: Journal    
DOI: 10.1177/1759091416642345     Document Type: Article

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