Cerebroside-A provides potent neuroprotection after cerebral ischaemia through reducing glutamate release and Ca 2+ influx of NMDA receptors

International Journal of Neuropsychopharmacology

Volumn 15, Issue 4, 2012, Pages 497-507

  Li, Lin ^a   Yang, Rong ^a   Sun, Kaiyue ^b   Bai, Yinyang ^a   Zhang, Zhuo ^a   Zhou, Libin ^a   Qi, Zhi ^c   Qi, Jianhua ^b   Chen, Ling ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c XIAMEN UNIVERSITY   (China)

Author keywords

Cerebral ischaemia; cerebroside (CS); large conductance Ca 2+ activated K + (BKCa) channel; NMDA receptor (NMDAR); oxygen glucose deprivation (OGD)

Indexed keywords

CALCIUM ACTIVATED POTASSIUM CHANNEL; CALCIUM ION; CEREBROSIDE; CEREBROSIDE A; CHARYBDOTOXIN; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION; BRAIN INJURY; BRAIN ISCHEMIA; CELL DEATH; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG MECHANISM; DRUG STRUCTURE; HIPPOCAMPAL CA1 REGION; LONG TERM POTENTIATION; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; OCCLUSIVE CEREBROVASCULAR DISEASE; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; STROKE;

6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ANALYSIS OF VARIANCE; ANIMALS; ANOXIA; BRAIN ISCHEMIA; CALCIUM; CEREBRAL INFARCTION; CEREBROSIDES; CHARYBDOTOXIN; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ELECTRIC STIMULATION; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; GLUCOSE; GLUTAMIC ACID; HIPPOCAMPUS; INFARCTION, MIDDLE CEREBRAL ARTERY; LONG-TERM POTENTIATION; MALE; MICE; MICE, INBRED C57BL; N-METHYLASPARTATE; NEUROPROTECTIVE AGENTS; NEUROTOXINS; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; TETRAZOLIUM SALTS; VALINE;

EID: 84862665658     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1017/S1461145711000654     Document Type: Article

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