A bioguided identification of the active compounds that contribute to the antiproliferative/cytotoxic effects of rosemary extract on colon cancer cells

Food and Chemical Toxicology

Volumn 80, Issue , 2015, Pages 215-222

  Borrás Linares, Isabel ^a,c   Pérez Sánchez, Almudena ^b   Lozano Sánchez, Jesús ^a,c   Barrajón Catalán, Enrique ^b   Arráez Román, David ^a,c   Cifuentes, Alejandro ^d   Micol, Vicente ^b,e   Carretero, Antonio Segura ^a,c  

^a UNIVERSITY OF GRANADA   (Spain)

^b MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

^c Research and Development of Functional Food Centre CIDAF   (Spain)

^d INSTITUTE OF FOOD SCIENCE RESEARCH CIAL   (Spain)

^e Instituto de Salud Carlos III   (Spain)

Author keywords

Antiproliferative activity; Colon cancer; Cytotoxicity; HPLC ESI QTOF MS; Rosemary; Terpenoids

Indexed keywords

12 METHOXYCARNOSIC ACID; ANEMOSAPOGENIN; ANTINEOPLASTIC AGENT; BETULIC ACID; CARNOSIC ACID; CARNOSOL; EPIISOROSMANOL; GENKWANIN; HINOKIONE; MILTIPOLONE; NOTOHAMOSIN B; PHARMACOLOGY; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; ROSMADIAL; ROSMANOL; ROSMARINUS OFFICINALIS EXTRACT; SHOGAOL; TAXODIONE; TERPENOID; UNCLASSIFIED DRUG; URSOLIC ACID;

ADENOCARCINOMA; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL; CELL PROLIFERATION; CELL VIABILITY; CHEMISTRY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DETERMINATION; DRUG EFFECTS; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG MECHANISM; DRUG POTENTIATION; DRUG THERAPY; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; PLANT LEAF; QUANTITATIVE ANALYSIS; ROSMARINUS; TIME OF FLIGHT MASS SPECTROMETRY; TUMOR CELL LINE;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CELL PROLIFERATION; CHEMISTRY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG EFFECTS; DRUG THERAPY; HUMANS; PHARMACOLOGY; PLANT EXTRACTS; PLANT LEAVES; ROSMARINUS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

ROSMARINUS OFFICINALIS;

EID: 84964252298     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2015.03.013     Document Type: Article

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