Carnosic acid modulates Akt/IKK/NF-κB signaling by PP2A and induces intrinsic and extrinsic pathway mediated apoptosis in human prostate carcinoma PC-3 cells

Apoptosis

Volumn 17, Issue 7, 2012, Pages 735-747

  Kar, Susanta ^a   Palit, Shreyasi ^a   Ball, Writoban Basu ^a   Das, Pijush K ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

Akt; Carnosic acid; NF B; PP2A; Prostate cancer

Indexed keywords

CALYCULIN A; CARNOSIC ACID; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; CYTOCHROME C; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; TRANSCRIPTION FACTOR RELA;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA BINDING; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; NICK END LABELING; PRIORITY JOURNAL; PROSTATE CARCINOMA; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN SECRETION; SIGNAL TRANSDUCTION;

APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; DITERPENES, ABIETANE; DOWN-REGULATION; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME ACTIVATION; HUMANS; I-KAPPA B KINASE; MALE; NF-KAPPA B; PLANT EXTRACTS; PROSTATIC NEOPLASMS; PROTEIN PHOSPHATASE 2; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

ROSMARINUS OFFICINALIS;

EID: 84862501584     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-012-0715-4     Document Type: Article

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