메뉴 건너뛰기




Volumn 23, Issue 9, 2016, Pages 1555-1564

The initiator caspase Dronc is subject of enhanced autophagy upon proteasome impairment in Drosophila

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY PROTEIN 7; CASPASE 3; CASPASE 9; CELL PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN 1; INITIATOR CASPASE; INITIATOR CASPASE DRONC; PROTEASOME; PROTEASOME SUBUNIT BETA 2; UBIQUITIN; UNCLASSIFIED DRUG; CASPASE; DROSOPHILA PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN; NC PROTEIN, DROSOPHILA; PROSBETA2 PROTEIN, DROSOPHILA; PROTEINASE; SMALL INTERFERING RNA; THREAD PROTEIN, DROSOPHILA;

EID: 84964240595     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2016.40     Document Type: Article
Times cited : (14)

References (79)
  • 1
    • 79952585579 scopus 로고    scopus 로고
    • Integration of clearance mechanisms: The proteasome and autophagy
    • Wong E, Cuervo AM. Integration of clearance mechanisms: the proteasome and autophagy. Cold Spring Harb Perspect Biol 2010; 2: a006734.
    • (2010) Cold Spring Harb Perspect Biol , vol.2 , pp. a006734
    • Wong, E.1    Cuervo, A.M.2
  • 2
    • 84901466274 scopus 로고    scopus 로고
    • Perilous journey: A tour of the ubiquitin-proteasome system
    • Kleiger G, Mayor T. Perilous journey: a tour of the ubiquitin-proteasome system. Trends Cell Biol 2014; 24: 352-359.
    • (2014) Trends Cell Biol , vol.24 , pp. 352-359
    • Kleiger, G.1    Mayor, T.2
  • 3
    • 84883451249 scopus 로고    scopus 로고
    • Selective autophagy: Talking with the UPS
    • Park C, Cuervo AM. Selective autophagy: talking with the UPS. Cell Biochem Biophys 2013; 67: 3-13.
    • (2013) Cell Biochem Biophys , vol.67 , pp. 3-13
    • Park, C.1    Cuervo, A.M.2
  • 4
    • 77956404377 scopus 로고    scopus 로고
    • Eaten alive: A history of macroautophagy
    • Yang Z, Klionsky DJ. Eaten alive: a history of macroautophagy. Nat Cell Biol 2010; 129: 814-822.
    • (2010) Nat Cell Biol , vol.129 , pp. 814-822
    • Yang, Z.1    Klionsky, D.J.2
  • 5
    • 1542344435 scopus 로고    scopus 로고
    • Proteasomes and their kin: Proteases in the machine age
    • Pickart CM, Cohen RE. Proteasomes and their kin: proteases in the machine age. Nat Rev Mol Cell Biol 2004; 5: 177-187.
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 177-187
    • Pickart, C.M.1    Cohen, R.E.2
  • 7
    • 0037101762 scopus 로고    scopus 로고
    • Assembly of the Drosophila 26 S proteasome is accompanied by extensive subunit rearrangements
    • Kurucz E, o I, Sumegi M, Holzl H, Kapelari B, Baumeister W et al. Assembly of the Drosophila 26 S proteasome is accompanied by extensive subunit rearrangements. Biochem J 2002; 365(Pt 2): 527-536.
    • (2002) Biochem J , vol.365 , pp. 527-536
    • Kurucz, E.I.1    Sumegi, M.2    Holzl, H.3    Kapelari, B.4    Baumeister, W.5
  • 8
    • 0036743483 scopus 로고    scopus 로고
    • Targeted expression of dominant negative proteasome mutants in Drosophila melanogaster
    • Belote JM, Fortier E. Targeted expression of dominant negative proteasome mutants in Drosophila melanogaster. Genesis 2002; 34: 80-82.
    • (2002) Genesis , vol.34 , pp. 80-82
    • Belote, J.M.1    Fortier, E.2
  • 9
    • 34248180045 scopus 로고    scopus 로고
    • A conditional yeast E1 mutant blocks the ubiquitin-proteasome pathway and reveals a role for ubiquitin conjugates in targeting Rad23 to the proteasome
    • Ghaboosi N, Deshaies RJ. A conditional yeast E1 mutant blocks the ubiquitin-proteasome pathway and reveals a role for ubiquitin conjugates in targeting Rad23 to the proteasome. Mol Biol Cell 2007; 18: 1953-1963.
    • (2007) Mol Biol Cell , vol.18 , pp. 1953-1963
    • Ghaboosi, N.1    Deshaies, R.J.2
  • 11
    • 84871940845 scopus 로고    scopus 로고
    • Development of proteasome inhibitors as research tools and cancer drugs
    • Goldberg AL. Development of proteasome inhibitors as research tools and cancer drugs. J Cell Biol 2012; 199: 583-588.
    • (2012) J Cell Biol , vol.199 , pp. 583-588
    • Goldberg, A.L.1
  • 12
    • 33745674468 scopus 로고    scopus 로고
    • Drug discovery in the ubiquitin-proteasome system
    • Nalepa G, Rolfe M, Harper JW. Drug discovery in the ubiquitin-proteasome system. Nat Rev Drug Discov 2006; 5: 596-613.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 596-613
    • Nalepa, G.1    Rolfe, M.2    Harper, J.W.3
  • 13
    • 84868148725 scopus 로고    scopus 로고
    • Failure of amino acid homeostasis causes cell death following proteasome inhibition
    • Suraweera A, Munch C, Hanssum A, Bertolotti A. Failure of amino acid homeostasis causes cell death following proteasome inhibition. Mol Cell 2012; 48: 242-253.
    • (2012) Mol Cell , vol.48 , pp. 242-253
    • Suraweera, A.1    Munch, C.2    Hanssum, A.3    Bertolotti, A.4
  • 14
    • 20344387475 scopus 로고    scopus 로고
    • Autophagy: Dual roles in life and death?
    • Baehrecke EH. Autophagy: dual roles in life and death? Nat Rev Mol Cell Biol 2005; 6: 505-510.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 505-510
    • Baehrecke, E.H.1
  • 15
    • 84937639381 scopus 로고    scopus 로고
    • Eaten alive: Novel insights into autophagy from multicellular model systems
    • Zhang H, Baehrecke EH. Eaten alive: novel insights into autophagy from multicellular model systems. Trends Cell Biol 2015; 25: 376-387.
    • (2015) Trends Cell Biol , vol.25 , pp. 376-387
    • Zhang, H.1    Baehrecke, E.H.2
  • 16
    • 36849021043 scopus 로고    scopus 로고
    • Atg7-dependent autophagy promotes neuronal health, stress tolerance, longevity but is dispensable for metamorphosis in Drosophila
    • Juhasz G, Erdi B, Sass M, Neufeld TP. Atg7-dependent autophagy promotes neuronal health, stress tolerance, longevity but is dispensable for metamorphosis in Drosophila. Genes Dev 2007; 21: 3061-3066.
    • (2007) Genes Dev , vol.21 , pp. 3061-3066
    • Juhasz, G.1    Erdi, B.2    Sass, M.3    Neufeld, T.P.4
  • 17
    • 4344563878 scopus 로고    scopus 로고
    • Role and regulation of starvation-induced autophagy in the Drosophila fat body
    • Scott RC, Schuldiner O, Neufeld TP. Role and regulation of starvation-induced autophagy in the Drosophila fat body. Dev Cell 2004; 7: 167-178.
    • (2004) Dev Cell , vol.7 , pp. 167-178
    • Scott, R.C.1    Schuldiner, O.2    Neufeld, T.P.3
  • 19
    • 84895890042 scopus 로고    scopus 로고
    • Proteasome failure promotes positioning of lysosomes around the aggresome via local block of microtubuledependent transport
    • Zaarur N, Meriin AB, Bejarano E, Xu X, Gabai VL, Cuervo AM et al. Proteasome failure promotes positioning of lysosomes around the aggresome via local block of microtubuledependent transport. Mol Cell Biol 2014; 34: 1336-1348.
    • (2014) Mol Cell Biol , vol.34 , pp. 1336-1348
    • Zaarur, N.1    Meriin, A.B.2    Bejarano, E.3    Xu, X.4    Gabai, V.L.5    Cuervo, A.M.6
  • 20
    • 77950487987 scopus 로고    scopus 로고
    • Mechanisms of cross-talk between the ubiquitinproteasome and autophagy-lysosome systems
    • Korolchuk VI, Menzies FM, Rubinsztein DC. Mechanisms of cross-talk between the ubiquitinproteasome and autophagy-lysosome systems. FEBS Lett 2010; 584: 1393-1398.
    • (2010) FEBS Lett , vol.584 , pp. 1393-1398
    • Korolchuk, V.I.1    Menzies, F.M.2    Rubinsztein, D.C.3
  • 21
    • 69449090071 scopus 로고    scopus 로고
    • A novel link between autophagy and the ubiquitin-proteasome system
    • Korolchuk VI, Menzies FM, Rubinsztein DC. A novel link between autophagy and the ubiquitin-proteasome system. Autophagy 2009; 5: 862-863.
    • (2009) Autophagy , vol.5 , pp. 862-863
    • Korolchuk, V.I.1    Menzies, F.M.2    Rubinsztein, D.C.3
  • 22
    • 34250183177 scopus 로고    scopus 로고
    • HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
    • Pandey UB, Nie Z, Batlevi Y, McCray BA, Ritson GP, Nedelsky NB et al. HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS. Nature 2007; 447: 859-863.
    • (2007) Nature , vol.447 , pp. 859-863
    • Pandey, U.B.1    Nie, Z.2    Batlevi, Y.3    McCray, B.A.4    Ritson, G.P.5    Nedelsky, N.B.6
  • 23
    • 34548299555 scopus 로고    scopus 로고
    • Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability
    • Ding WX, Ni HM, Gao W, Yoshimori T, Stolz DB, Ron D et al. Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. Am J Pathol 2007; 171: 513-524.
    • (2007) Am J Pathol , vol.171 , pp. 513-524
    • Ding, W.X.1    Ni, H.M.2    Gao, W.3    Yoshimori, T.4    Stolz, D.B.5    Ron, D.6
  • 24
    • 75149175502 scopus 로고    scopus 로고
    • Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells
    • Zhu K, Dunner K Jr., McConkey DJ. Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells. Oncogene 2010; 29: 451-462.
    • (2010) Oncogene , vol.29 , pp. 451-462
    • Zhu, K.1    Dunner, Jr.K.2    McConkey, D.J.3
  • 25
  • 26
    • 78349276861 scopus 로고    scopus 로고
    • Autophagy is activated by proteasomal inhibition and involved in aggresome clearance in cultured astrocytes
    • Janen SB, Chaachouay H, Richter-Landsberg C. Autophagy is activated by proteasomal inhibition and involved in aggresome clearance in cultured astrocytes. Glia 2010; 58: 1766-1774.
    • (2010) Glia , vol.58 , pp. 1766-1774
    • Janen, S.B.1    Chaachouay, H.2    Richter-Landsberg, C.3
  • 27
    • 84872309097 scopus 로고    scopus 로고
    • Detrimental effects of proteasome inhibition activity in Drosophila melanogaster: Implication of ER stress, autophagy, apoptosis
    • Velentzas PD, Velentzas AD, Mpakou VE, Antonelou MH, Margaritis LH, Papassideri IS et al. Detrimental effects of proteasome inhibition activity in Drosophila melanogaster: implication of ER stress, autophagy, apoptosis. Cell Biol Toxicol 2013; 29: 13-37.
    • (2013) Cell Biol Toxicol , vol.29 , pp. 13-37
    • Velentzas, P.D.1    Velentzas, A.D.2    Mpakou, V.E.3    Antonelou, M.H.4    Margaritis, L.H.5    Papassideri, I.S.6
  • 28
    • 84893491874 scopus 로고    scopus 로고
    • Crosstalk between autophagy and proteasome protein degradation systems: Possible implications for cancer therapy
    • Wojcik S. Crosstalk between autophagy and proteasome protein degradation systems: possible implications for cancer therapy. Folia Histochem Cytobiol/Pol Acad Sci Pol Histochem Cytochem Soc 2013; 51: 249-264.
    • (2013) Folia Histochem Cytobiol/Pol Acad Sci Pol Histochem Cytochem Soc , vol.51 , pp. 249-264
    • Wojcik, S.1
  • 29
    • 77951248828 scopus 로고    scopus 로고
    • Autophagy: Links with the proteasome
    • Lamark T, Johansen T. Autophagy: links with the proteasome. Curr Opin Cell Biol 2010; 22: 192-198.
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 192-198
    • Lamark, T.1    Johansen, T.2
  • 30
    • 34548259958 scopus 로고    scopus 로고
    • P62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
    • Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H et al. p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem 2007; 282: 24131-24145.
    • (2007) J Biol Chem , vol.282 , pp. 24131-24145
    • Pankiv, S.1    Clausen, T.H.2    Lamark, T.3    Brech, A.4    Bruun, J.A.5    Outzen, H.6
  • 31
    • 33645926989 scopus 로고    scopus 로고
    • P62/SQSTM1: A missing link between protein aggregates and the autophagy machinery
    • Bjorkoy G, Lamark T, Johansen T. p62/SQSTM1: a missing link between protein aggregates and the autophagy machinery. Autophagy 2006; 2: 138-139.
    • (2006) Autophagy , vol.2 , pp. 138-139
    • Bjorkoy, G.1    Lamark, T.2    Johansen, T.3
  • 32
    • 27944504351 scopus 로고    scopus 로고
    • P62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
    • Bjorkoy G, Lamark T, Brech A, Outzen H, Perander M, Overvatn A et al. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J Cell Biol 2005; 171: 603-614.
    • (2005) J Cell Biol , vol.171 , pp. 603-614
    • Bjorkoy, G.1    Lamark, T.2    Brech, A.3    Outzen, H.4    Perander, M.5    Overvatn, A.6
  • 33
    • 84863425313 scopus 로고    scopus 로고
    • P62 at the interface of autophagy, oxidative stress signaling, cancer
    • Nezis IP, Stenmark H. p62 at the interface of autophagy, oxidative stress signaling, cancer. Antioxidants Redox Signal 2012; 17: 786-793.
    • (2012) Antioxidants Redox Signal , vol.17 , pp. 786-793
    • Nezis, I.P.1    Stenmark, H.2
  • 34
    • 79957916551 scopus 로고    scopus 로고
    • P62, Ref (2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects
    • Bartlett BJ, Isakson P, Lewerenz J, Sanchez H, Kotzebue RW, Cumming RC et al. p62, Ref (2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects. Autophagy 2011; 7: 572-583.
    • (2011) Autophagy , vol.7 , pp. 572-583
    • Bartlett, B.J.1    Isakson, P.2    Lewerenz, J.3    Sanchez, H.4    Kotzebue, R.W.5    Cumming, R.C.6
  • 35
    • 84892859905 scopus 로고    scopus 로고
    • Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy
    • Rogov V, Dotsch V, Johansen T, Kirkin V. Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy. Mol Cell 2014; 53: 167-178.
    • (2014) Mol Cell , vol.53 , pp. 167-178
    • Rogov, V.1    Dotsch, V.2    Johansen, T.3    Kirkin, V.4
  • 37
    • 84866170154 scopus 로고    scopus 로고
    • Autophagy impairment: A crossroad between neurodegeneration and tauopathies
    • Nassif M, Hetz C. Autophagy impairment: a crossroad between neurodegeneration and tauopathies. BMC Biol 2012; 10: 78.
    • (2012) BMC Biol , vol.10 , pp. 78
    • Nassif, M.1    Hetz, C.2
  • 39
    • 78049502859 scopus 로고    scopus 로고
    • Apoptosis, stem cells, tissue regeneration
    • Bergmann A, Steller H. Apoptosis, stem cells, tissue regeneration. Sci Signal 2010; 3: re8.
    • (2010) Sci Signal , vol.3 , pp. re8
    • Bergmann, A.1    Steller, H.2
  • 40
    • 84930044531 scopus 로고    scopus 로고
    • Live to die another way: Modes of programmed cell death and the signals emanating from dying cells
    • Fuchs Y, Steller H. Live to die another way: modes of programmed cell death and the signals emanating from dying cells. Nat Rev Mol Cell Biol 2015; 16: 329-344.
    • (2015) Nat Rev Mol Cell Biol , vol.16 , pp. 329-344
    • Fuchs, Y.1    Steller, H.2
  • 41
    • 33845480548 scopus 로고    scopus 로고
    • Caspase function in programmed cell death
    • Kumar S. Caspase function in programmed cell death. Cell Death Differ 2007; 14: 32-43.
    • (2007) Cell Death Differ , vol.14 , pp. 32-43
    • Kumar, S.1
  • 43
    • 81055125652 scopus 로고    scopus 로고
    • Programmed cell death in animal development and disease
    • Fuchs Y, Steller H. Programmed cell death in animal development and disease. Cell 2011; 147: 742-758.
    • (2011) Cell , vol.147 , pp. 742-758
    • Fuchs, Y.1    Steller, H.2
  • 44
  • 45
    • 0242574748 scopus 로고    scopus 로고
    • Molecular mechanism of Reaper-Grim-Hid-mediated suppression of DIAP1-dependent Dronc ubiquitination
    • Chai J, Yan N, Huh JR, Wu JW, Li W, Hay BA et al. Molecular mechanism of Reaper-Grim-Hid-mediated suppression of DIAP1-dependent Dronc ubiquitination. Nat Struct Biol 2003; 10: 892-898.
    • (2003) Nat Struct Biol , vol.10 , pp. 892-898
    • Chai, J.1    Yan, N.2    Huh, J.R.3    Wu, J.W.4    Li, W.5    Hay, B.A.6
  • 46
    • 0346668315 scopus 로고    scopus 로고
    • The Drosophila DIAP1 protein is required to prevent accumulation of a continuously generated, processed form of the apical caspase DRONC
    • Muro I, Hay BA, Clem RJ. The Drosophila DIAP1 protein is required to prevent accumulation of a continuously generated, processed form of the apical caspase DRONC. J Biol Chem 2002; 277: 49644-49650.
    • (2002) J Biol Chem , vol.277 , pp. 49644-49650
    • Muro, I.1    Hay, B.A.2    Clem, R.J.3
  • 47
    • 0036300214 scopus 로고    scopus 로고
    • The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis
    • Wilson R, Goyal L, Ditzel M, Zachariou A, Baker DA, Agapite J et al. The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis. Nat Cell Biol 2002; 4: 445-450.
    • (2002) Nat Cell Biol , vol.4 , pp. 445-450
    • Wilson, R.1    Goyal, L.2    Ditzel, M.3    Zachariou, A.4    Baker, D.A.5    Agapite, J.6
  • 48
    • 55949118522 scopus 로고    scopus 로고
    • Inactivation of effector caspases through non-degradative polyubiquitylation
    • Ditzel M, Broemer M, Tenev T, Bolduc C, Lee TV, Rigbolt KTG et al. Inactivation of effector caspases through non-degradative polyubiquitylation. Mol Cell 2008; 32: 540-553.
    • (2008) Mol Cell , vol.32 , pp. 540-553
    • Ditzel, M.1    Broemer, M.2    Tenev, T.3    Bolduc, C.4    Lee, T.V.5    Ktg, R.6
  • 49
    • 80053439574 scopus 로고    scopus 로고
    • Drosophila IAP1-mediated ubiquitylation controls activation of the initiator caspase DRONC independent of protein degradation
    • Lee TV, Fan Y, Wang S, Srivastava M, Broemer M, Meier P et al. Drosophila IAP1-mediated ubiquitylation controls activation of the initiator caspase DRONC independent of protein degradation. PLoS Genet 2011; 7: e1002261.
    • (2011) PLoS Genet , vol.7 , pp. e1002261
    • Lee, T.V.1    Fan, Y.2    Wang, S.3    Srivastava, M.4    Broemer, M.5    Meier, P.6
  • 50
    • 50049110244 scopus 로고    scopus 로고
    • Regulation of apoptosis by XIAP ubiquitin-ligase activity
    • Schile AJ, Garcia-Fernandez M, Steller H. Regulation of apoptosis by XIAP ubiquitin-ligase activity. Genes Dev 2008; 22: 2256-2266.
    • (2008) Genes Dev , vol.22 , pp. 2256-2266
    • Schile, A.J.1    Garcia-Fernandez, M.2    Steller, H.3
  • 51
    • 0032897575 scopus 로고    scopus 로고
    • The dominant temperature-sensitive lethal DTS7 of Drosophila melanogaster encodes an altered 20S proteasome beta-type subunit
    • Smyth KA, Belote JM. The dominant temperature-sensitive lethal DTS7 of Drosophila melanogaster encodes an altered 20S proteasome beta-type subunit. Genetics 1999; 151: 211-220.
    • (1999) Genetics , vol.151 , pp. 211-220
    • Smyth, K.A.1    Belote, J.M.2
  • 52
    • 0342297875 scopus 로고    scopus 로고
    • The regulatory complex of Drosophila melanogaster 26S proteasomes. Subunit composition and localization of a deubiquitylating enzyme
    • Holzl H, Kapelari B, Kellermann J, Seemuller E, Sumegi M, Udvardy A et al. The regulatory complex of Drosophila melanogaster 26S proteasomes. Subunit composition and localization of a deubiquitylating enzyme. J Cell Biol 2000; 150: 119-130.
    • (2000) J Cell Biol , vol.150 , pp. 119-130
    • Holzl, H.1    Kapelari, B.2    Kellermann, J.3    Seemuller, E.4    Sumegi, M.5    Udvardy, A.6
  • 53
    • 0034053414 scopus 로고    scopus 로고
    • Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics
    • Newsome TP, Asling B, Dickson BJ. Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics. Development 2000; 127: 851-860.
    • (2000) Development , vol.127 , pp. 851-860
    • Newsome, T.P.1    Asling, B.2    Dickson, B.J.3
  • 54
    • 0027267041 scopus 로고
    • Analysis of genetic mosaics in developing and adult Drosophila tissues
    • Xu T, Rubin GM. Analysis of genetic mosaics in developing and adult Drosophila tissues. Development 1993; 117: 1223-1237.
    • (1993) Development , vol.117 , pp. 1223-1237
    • Xu, T.1    Rubin, G.M.2
  • 55
    • 0028070372 scopus 로고
    • Production and characterization of monoclonal antibodies specific to multi-ubiquitin chains of polyubiquitinated proteins
    • Fujimuro M, Sawada H, Yokosawa H. Production and characterization of monoclonal antibodies specific to multi-ubiquitin chains of polyubiquitinated proteins. FEBS Lett 1994; 349: 173-180.
    • (1994) FEBS Lett , vol.349 , pp. 173-180
    • Fujimuro, M.1    Sawada, H.2    Yokosawa, H.3
  • 56
    • 0030662038 scopus 로고    scopus 로고
    • Dynamics of ubiquitin conjugation during heat-shock response revealed by using a monoclonal antibody specific to multi-ubiquitin chains
    • Fujimuro M, Sawada H, Yokosawa H. Dynamics of ubiquitin conjugation during heat-shock response revealed by using a monoclonal antibody specific to multi-ubiquitin chains. Eur J Biochem 1997; 249: 427-433.
    • (1997) Eur J Biochem , vol.249 , pp. 427-433
    • Fujimuro, M.1    Sawada, H.2    Yokosawa, H.3
  • 57
    • 84879787188 scopus 로고    scopus 로고
    • Impaired proteasomal degradation enhances autophagy via hypoxia signaling in Drosophila
    • Low P, Varga A, Pircs K, Nagy P, Szatmari Z, Sass M et al. Impaired proteasomal degradation enhances autophagy via hypoxia signaling in Drosophila. BMC Cell Biol 2013; 14: 29.
    • (2013) BMC Cell Biol , vol.14 , pp. 29
    • Low, P.1    Varga, A.2    Pircs, K.3    Nagy, P.4    Szatmari, Z.5    Sass, M.6
  • 58
    • 77956880563 scopus 로고    scopus 로고
    • Metabolic regulation of Drosophila apoptosis through inhibitory phosphorylation of Dronc
    • Yang CS, Thomenius MJ, Gan EC, Tang W, Freel CD, Merritt TJ et al. Metabolic regulation of Drosophila apoptosis through inhibitory phosphorylation of Dronc. EMBO J 2010; 29: 3196-3207.
    • (2010) EMBO J , vol.29 , pp. 3196-3207
    • Yang, C.S.1    Thomenius, M.J.2    Gan, E.C.3    Tang, W.4    Freel, C.D.5    Merritt, T.J.6
  • 59
    • 0036307854 scopus 로고    scopus 로고
    • Morgue mediates apoptosis in the Drosophila melanogaster retina by promoting degradation of DIAP1
    • Hays R, Wickline L, Cagan R. Morgue mediates apoptosis in the Drosophila melanogaster retina by promoting degradation of DIAP1. Nat Cell Biol 2002; 4: 425-431.
    • (2002) Nat Cell Biol , vol.4 , pp. 425-431
    • Hays, R.1    Wickline, L.2    Cagan, R.3
  • 60
    • 0036303143 scopus 로고    scopus 로고
    • Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition
    • Holley CL, Olson MR, Colon-Ramos DA, Kornbluth S. Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition. Nat Cell Biol 2002; 4: 439-444.
    • (2002) Nat Cell Biol , vol.4 , pp. 439-444
    • Holley, C.L.1    Olson, M.R.2    Colon-Ramos, D.A.3    Kornbluth, S.4
  • 61
    • 0036300083 scopus 로고    scopus 로고
    • Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1
    • Ryoo HD, Bergmann A, Gonen H, Ciechanover A, Steller H. Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1. Nat Cell Biol 2002; 4: 432-438.
    • (2002) Nat Cell Biol , vol.4 , pp. 432-438
    • Ryoo, H.D.1    Bergmann, A.2    Gonen, H.3    Ciechanover, A.4    Steller, H.5
  • 62
    • 0036300082 scopus 로고    scopus 로고
    • Hid Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms
    • Yoo SJ, Huh JR, Muro I, Yu H, Wang L, Wang SL et al. Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms. Nat Cell Biol 2002; 4: 416-424.
    • (2002) Nat Cell Biol , vol.4 , pp. 416-424
    • Yoo, S.J.1    Huh, J.R.2    Muro, I.3    Yu, H.4    Wang, L.5    Wang, S.L.6
  • 63
    • 0035341376 scopus 로고    scopus 로고
    • Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural development
    • Lee T, Luo L. Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural development. Trends Neurosci 2001; 24: 251-254.
    • (2001) Trends Neurosci , vol.24 , pp. 251-254
    • Lee, T.1    Luo, L.2
  • 64
    • 0033613272 scopus 로고    scopus 로고
    • Dominant-negative mutation in the beta2 and beta6 proteasome subunit genes affect alternative cell fate decisions in the Drosophila sense organ lineage
    • Schweisguth F. Dominant-negative mutation in the beta2 and beta6 proteasome subunit genes affect alternative cell fate decisions in the Drosophila sense organ lineage. Proc Natl Acad Sci USA 1999; 96: 11382-11386.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 11382-11386
    • Schweisguth, F.1
  • 65
    • 27244440860 scopus 로고    scopus 로고
    • Dendrite-specific remodeling of Drosophila sensory neurons requires matrix metalloproteases, ubiquitin-proteasome, ecdysone signaling
    • Kuo CT, Jan LY, Jan YN. Dendrite-specific remodeling of Drosophila sensory neurons requires matrix metalloproteases, ubiquitin-proteasome, ecdysone signaling. Proc Natl Acad Sci USA 2005; 102: 15230-15235.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15230-15235
    • Kuo, C.T.1    Jan, L.Y.2    Jan, Y.N.3
  • 66
    • 33746363831 scopus 로고    scopus 로고
    • Identification of E2/E3 ubiquitinating enzymes and caspase activity regulating Drosophila sensory neuron dendrite pruning
    • Kuo CT, Zhu S, Younger S, Jan LY, Jan YN. Identification of E2/E3 ubiquitinating enzymes and caspase activity regulating Drosophila sensory neuron dendrite pruning. Neuron 2006; 51: 283-290.
    • (2006) Neuron , vol.51 , pp. 283-290
    • Kuo, C.T.1    Zhu, S.2    Younger, S.3    Jan, L.Y.4    Jan, Y.N.5
  • 67
    • 0038198738 scopus 로고    scopus 로고
    • Axon pruning during Drosophila metamorphosis: Evidence for local degeneration and requirement of the ubiquitin-proteasome system
    • Watts RJ, Hoopfer ED, Luo L. Axon pruning during Drosophila metamorphosis: evidence for local degeneration and requirement of the ubiquitin-proteasome system. Neuron 2003; 38: 871-885.
    • (2003) Neuron , vol.38 , pp. 871-885
    • Watts, R.J.1    Hoopfer, E.D.2    Luo, L.3
  • 70
    • 4344659685 scopus 로고    scopus 로고
    • Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy
    • Cuervo AM, Stefanis L, Fredenburg R, Lansbury PT, Sulzer D. Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy. Science 2004; 305: 1292-1295.
    • (2004) Science , vol.305 , pp. 1292-1295
    • Cuervo, A.M.1    Stefanis, L.2    Fredenburg, R.3    Lansbury, P.T.4    Sulzer, D.5
  • 71
    • 0031595780 scopus 로고    scopus 로고
    • IkappaB is a substrate for a selective pathway of lysosomal proteolysis
    • Cuervo AM, Hu W, Lim B, Dice JF. IkappaB is a substrate for a selective pathway of lysosomal proteolysis. Mol Biol Cell 1998; 9: 1995-2010.
    • (1998) Mol Biol Cell , vol.9 , pp. 1995-2010
    • Cuervo, A.M.1    Hu, W.2    Lim, B.3    Dice, J.F.4
  • 72
    • 38949096081 scopus 로고    scopus 로고
    • Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome
    • Ding WX, Yin XM. Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome. Autophagy 2008; 4: 141-150.
    • (2008) Autophagy , vol.4 , pp. 141-150
    • Ding, W.X.1    Yin, X.M.2
  • 73
    • 31144456216 scopus 로고    scopus 로고
    • Mis-specified cells die by an active gene-directed process, inhibition of this death results in cell fate transformation in Drosophila
    • Werz C, Lee TV, Lee PL, Lackey M, Bolduc C, Stein DS et al. Mis-specified cells die by an active gene-directed process, inhibition of this death results in cell fate transformation in Drosophila. Development 2005; 132: 5343-5352.
    • (2005) Development , vol.132 , pp. 5343-5352
    • Werz, C.1    Lee, T.V.2    Lee, P.L.3    Lackey, M.4    Bolduc, C.5    Stein, D.S.6
  • 74
    • 3142686745 scopus 로고    scopus 로고
    • The BDGP gene disruption project: Single transposon insertions associated with 40% of Drosophila genes
    • Bellen HJ, Levis RW, Liao G, He Y, Carlson JW, Tsang G et al. The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. Genetics 2004; 167: 761-781.
    • (2004) Genetics , vol.167 , pp. 761-781
    • Bellen, H.J.1    Levis, R.W.2    Liao, G.3    He, Y.4    Carlson, J.W.5    Tsang, G.6
  • 75
    • 36849088609 scopus 로고    scopus 로고
    • Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila
    • Berry DL, Baehrecke EH. Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila. Cell 2007; 131: 1137-1148.
    • (2007) Cell , vol.131 , pp. 1137-1148
    • Berry, D.L.1    Baehrecke, E.H.2
  • 76
    • 84958755102 scopus 로고    scopus 로고
    • Detecting caspase activity in Drosophila larval imaginal discs
    • Fogarty CE, Bergmann A. Detecting caspase activity in Drosophila larval imaginal discs. Methods Mol Biol 2014; 1133: 109-117.
    • (2014) Methods Mol Biol , vol.1133 , pp. 109-117
    • Fogarty, C.E.1    Bergmann, A.2
  • 77
    • 70350571244 scopus 로고    scopus 로고
    • Autophagy, not apoptosis, is essential for midgut cell death in Drosophila
    • Denton D, Shravage B, Simin R, Mills K, Berry DL, Baehrecke EH et al. Autophagy, not apoptosis, is essential for midgut cell death in Drosophila. Curr Biol 2009; 19: 1741-1746.
    • (2009) Curr Biol , vol.19 , pp. 1741-1746
    • Denton, D.1    Shravage, B.2    Simin, R.3    Mills, K.4    Berry, D.L.5    Baehrecke, E.H.6
  • 78
    • 84863728064 scopus 로고    scopus 로고
    • Relationship between growth arrest and autophagy in midgut programmed cell death in Drosophila
    • Denton D, Chang TK, Nicolson S, Shravage B, Simin R, Baehrecke EH et al. Relationship between growth arrest and autophagy in midgut programmed cell death in Drosophila. Cell Death Differ 2012; 19: 1299-1307.
    • (2012) Cell Death Differ , vol.19 , pp. 1299-1307
    • Denton, D.1    Chang, T.K.2    Nicolson, S.3    Shravage, B.4    Simin, R.5    Baehrecke, E.H.6
  • 79
    • 84870672304 scopus 로고    scopus 로고
    • Translational control by the DEAD box RNA helicase belle regulates ecdysone-triggered transcriptional cascades
    • Ihry RJ, Sapiro AL, Bashirullah A. Translational control by the DEAD box RNA helicase belle regulates ecdysone-triggered transcriptional cascades. PLoS Genet 2012; 8: e1003085.
    • (2012) PLoS Genet , vol.8 , pp. e1003085
    • Ihry, R.J.1    Sapiro, A.L.2    Bashirullah, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.