-
1
-
-
33747771435
-
Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC phases one and three repeat multicountry cross-sectional surveys
-
ISAAC Phase Three Study Group
-
Asher MI, Montefort S, Björkstén B, Lai CK, Strachan DP, Weiland SK, Williams H; ISAAC Phase Three Study Group. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC phases one and three repeat multicountry cross-sectional surveys. Lancet 2006; 368:733-743.
-
(2006)
Lancet
, vol.368
, pp. 733-743
-
-
Asher, M.I.1
Montefort, S.2
Björkstén, B.3
Lai, C.K.4
Strachan, D.P.5
Weiland, S.K.6
Williams, H.7
-
2
-
-
84871395067
-
Lung microbiology and exacerbations in COPD
-
Beasley V, Joshi PV, Singanayagam A, Molyneaux PL, Johnston SL, Mallia P. Lung microbiology and exacerbations in COPD. Int J Chron Obstruct Pulmon Dis 2012;7:555-569.
-
(2012)
Int J Chron Obstruct Pulmon Dis
, vol.7
, pp. 555-569
-
-
Beasley, V.1
Joshi, P.V.2
Singanayagam, A.3
Molyneaux, P.L.4
Johnston, S.L.5
Mallia, P.6
-
3
-
-
0036794862
-
Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease
-
Donaldson GC, Seemungal TA, Bhowmik A, Wedzicha JA. Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease. Thorax 2002;57:847-852.
-
(2002)
Thorax
, vol.57
, pp. 847-852
-
-
Donaldson, G.C.1
Seemungal, T.A.2
Bhowmik, A.3
Wedzicha, J.A.4
-
4
-
-
0028990124
-
Community study of role of viral infections in exacerbations of asthma in 9-11 year old children
-
Johnston SL, Pattemore PK, Sanderson G, Smith S, Lampe F, Josephs L, Symington P, OToole S, Myint SH, Tyrrell DA, et al. Community study of role of viral infections in exacerbations of asthma in 9-11 year old children. BMJ 1995;310:1225-1229.
-
(1995)
BMJ
, vol.310
, pp. 1225-1229
-
-
Johnston, S.L.1
Pattemore, P.K.2
Sanderson, G.3
Smith, S.4
Lampe, F.5
Josephs, L.6
Symington, P.7
Otoole, S.8
Myint, S.H.9
Tyrrell, D.A.10
-
5
-
-
77952695527
-
The role of viruses in acute exacerbations of asthma
-
Jackson DJ, Johnston SL. The role of viruses in acute exacerbations of asthma. J Allergy Clin Immunol 2010;125:1178-1187.
-
(2010)
J Allergy Clin Immunol
, vol.125
, pp. 1178-1187
-
-
Jackson, D.J.1
Johnston, S.L.2
-
6
-
-
0037045846
-
Frequency, severity, and duration of rhinovirus infections in asthmatic and non-Asthmatic individuals: A longitudinal cohort study
-
Corne JM, Marshall C, Smith S, Schreiber J, Sanderson G, Holgate ST, Johnston SL. Frequency, severity, and duration of rhinovirus infections in asthmatic and non-Asthmatic individuals: A longitudinal cohort study. Lancet 2002;359:831-834.
-
(2002)
Lancet
, vol.359
, pp. 831-834
-
-
Corne, J.M.1
Marshall, C.2
Smith, S.3
Schreiber, J.4
Sanderson, G.5
Holgate, S.T.6
Johnston, S.L.7
-
7
-
-
33846837480
-
Prevalence of viral respiratory tract infections in children with asthma
-
Khetsuriani N, Kazerouni NN, Erdman DD, Lu X, Redd SC, Anderson LJ, Teague WG. Prevalence of viral respiratory tract infections in children with asthma. J Allergy Clin Immunol 2007;119:314-321.
-
(2007)
J Allergy Clin Immunol
, vol.119
, pp. 314-321
-
-
Khetsuriani, N.1
Kazerouni, N.N.2
Erdman, D.D.3
Lu, X.4
Redd, S.C.5
Anderson, L.J.6
Teague, W.G.7
-
9
-
-
84880171452
-
Proposals for the classification of human rhinovirus species A, B and C into genotypically assigned types
-
McIntyre CL, Knowles NJ, Simmonds P. Proposals for the classification of human rhinovirus species A, B and C into genotypically assigned types. J Gen Virol 2013;94:1791-1806.
-
(2013)
J Gen Virol
, vol.94
, pp. 1791-1806
-
-
McIntyre, C.L.1
Knowles, N.J.2
Simmonds, P.3
-
10
-
-
84928689999
-
Cadherin-related family member 3, a childhood asthma susceptibility gene product, mediates rhinovirus C binding and replication
-
Bochkov YA, Watters K, Ashraf S, Griggs TF, Devries MK, Jackson DJ, Palmenberg AC, Gern JE. Cadherin-related family member 3, a childhood asthma susceptibility gene product, mediates rhinovirus C binding and replication. Proc Natl Acad Sci USA 2015;112: 5485-5490.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. 5485-5490
-
-
Bochkov, Y.A.1
Watters, K.2
Ashraf, S.3
Griggs, T.F.4
Devries, M.K.5
Jackson, D.J.6
Palmenberg, A.C.7
Gern, J.E.8
-
11
-
-
0034050930
-
Rhinoviruses infect the lower airways
-
Papadopoulos NG, Bates PJ, Bardin PG, Papi A, Leir SH, Fraenkel DJ, Meyer J, Lackie PM, Sanderson G, Holgate ST, et al. Rhinoviruses infect the lower airways. J Infect Dis 2000;181:1875-1884.
-
(2000)
J Infect Dis
, vol.181
, pp. 1875-1884
-
-
Papadopoulos, N.G.1
Bates, P.J.2
Bardin, P.G.3
Papi, A.4
Leir, S.H.5
Fraenkel, D.J.6
Meyer, J.7
Lackie, P.M.8
Sanderson, G.9
Holgate, S.T.10
-
12
-
-
79251492014
-
Co-ordinated role of TLR3 RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium
-
Slater L, Bartlett NW, Haas JJ, Zhu J, Message SD, Walton RP, Sykes A, Dahdaleh S, Clarke DL, Belvisi MG, et al. Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium. PLoS Pathog 2010;6:e1001178.
-
(2010)
PLoS Pathog
, vol.6
, pp. e1001178
-
-
Slater, L.1
Bartlett, N.W.2
Haas, J.J.3
Zhu, J.4
Message, S.D.5
Walton, R.P.6
Sykes, A.7
Dahdaleh, S.8
Clarke, D.L.9
Belvisi, M.G.10
-
13
-
-
3242813113
-
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
-
Yoneyama M, Kikuchi M, Natsukawa T, Shinobu N, Imaizumi T, Miyagishi M, Taira K, Akira S, Fujita T. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol 2004;5:730-737.
-
(2004)
Nat Immunol
, vol.5
, pp. 730-737
-
-
Yoneyama, M.1
Kikuchi, M.2
Natsukawa, T.3
Shinobu, N.4
Imaizumi, T.5
Miyagishi, M.6
Taira, K.7
Akira, S.8
Fujita, T.9
-
14
-
-
25144439512
-
Toll-like receptor 3 is induced by and mediates antiviral activity against rhinovirus infection of human bronchial epithelial cells
-
Hewson CA, Jardine A, Edwards MR, Laza-Stanca V, Johnston SL. Toll-like receptor 3 is induced by and mediates antiviral activity against rhinovirus infection of human bronchial epithelial cells. J Virol 2005;79:12273-12279.
-
(2005)
J Virol
, vol.79
, pp. 12273-12279
-
-
Hewson, C.A.1
Jardine, A.2
Edwards, M.R.3
Laza-Stanca, V.4
Johnston, S.L.5
-
15
-
-
32044440119
-
Rhinovirus induces airway epithelial gene expression through double-stranded RNA and IFNdependent pathways
-
Chen Y, Hamati E, Lee PK, Lee WM, Wachi S, Schnurr D, Yagi S, Dolganov G, Boushey H, Avila P, et al. Rhinovirus induces airway epithelial gene expression through double-stranded RNA and IFNdependent pathways. Am J Respir Cell Mol Biol 2006;34:192-203.
-
(2006)
Am J Respir Cell Mol Biol
, vol.34
, pp. 192-203
-
-
Chen, Y.1
Hamati, E.2
Lee, P.K.3
Lee, W.M.4
Wachi, S.5
Schnurr, D.6
Yagi, S.7
Dolganov, G.8
Boushey, H.9
Avila, P.10
-
16
-
-
0032526639
-
Low grade rhinovirus infection induces a prolonged release of IL-8 in pulmonary epithelium
-
Johnston SL, Papi A, Bates PJ, Mastronarde JG, Monick MM, Hunninghake GW. Low grade rhinovirus infection induces a prolonged release of IL-8 in pulmonary epithelium. J Immunol 1998; 160:6172-6181.
-
(1998)
J Immunol
, vol.160
, pp. 6172-6181
-
-
Johnston, S.L.1
Papi, A.2
Bates, P.J.3
Mastronarde, J.G.4
Monick, M.M.5
Hunninghake, G.W.6
-
17
-
-
33845464265
-
Human rhinovirus induces robust IP-10 release by monocytic cells, which is independent of viral replication but linked to type i interferon receptor ligation and STAT1 activation
-
Korpi-Steiner NL, Bates ME, Lee WM, Hall DJ, Bertics PJ. Human rhinovirus induces robust IP-10 release by monocytic cells, which is independent of viral replication but linked to type I interferon receptor ligation and STAT1 activation. J Leukoc Biol 2006;80:1364-1374.
-
(2006)
J Leukoc Biol
, vol.80
, pp. 1364-1374
-
-
Korpi-Steiner, N.L.1
Bates, M.E.2
Lee, W.M.3
Hall, D.J.4
Bertics, P.J.5
-
18
-
-
33746802360
-
Rhinovirus replication in human macrophages induces NF-kappaB-dependent tumor necrosis factor alpha production
-
Laza-Stanca V, Stanciu LA, Message SD, Edwards MR, Gern JE, Johnston SL. Rhinovirus replication in human macrophages induces NF-kappaB-dependent tumor necrosis factor alpha production. J Virol 2006;80:8248-8258.
-
(2006)
J Virol
, vol.80
, pp. 8248-8258
-
-
Laza-Stanca, V.1
Stanciu, L.A.2
Message, S.D.3
Edwards, M.R.4
Gern, J.E.5
Johnston, S.L.6
-
19
-
-
0030696032
-
Rhinovirus stimulation of interleukin-8 in vivo and in vitro: Role of NF-kappaB
-
Zhu Z, Tang W, Gwaltney JM Jr, Wu Y, Elias JA. Rhinovirus stimulation of interleukin-8 in vivo and in vitro: role of NF-kappaB. Am J Physiol 1997;273:L814-L824.
-
(1997)
Am J Physiol
, vol.273
, pp. L814-L824
-
-
Zhu, Z.1
Tang, W.2
Gwaltney, J.M.3
Wu, Y.4
Elias, J.A.5
-
20
-
-
34447530935
-
Corticosteroids and beta2 agonists differentially regulate rhinovirusinduced interleukin-6 via distinct Cis-Acting elements
-
Edwards MR, Haas J, Panettieri RA Jr, Johnson M, Johnston SL. Corticosteroids and beta2 agonists differentially regulate rhinovirusinduced interleukin-6 via distinct Cis-Acting elements. J Biol Chem 2007;282:15366-15375.
-
(2007)
J Biol Chem
, vol.282
, pp. 15366-15375
-
-
Edwards, M.R.1
Haas, J.2
Panettieri, R.A.3
Johnson, M.4
Johnston, S.L.5
-
21
-
-
20844440294
-
Human airway epithelial cells produce IP-10 (CXCL10) in vitro and in vivo upon rhinovirus infection
-
Spurrell JC, Wiehler S, Zaheer RS, Sanders SP, Proud D. Human airway epithelial cells produce IP-10 (CXCL10) in vitro and in vivo upon rhinovirus infection. Am J Physiol Lung Cell Mol Physiol 2005;289: L85-L95.
-
(2005)
Am J Physiol Lung Cell Mol Physiol
, vol.289
, pp. L85-L95
-
-
Spurrell, J.C.1
Wiehler, S.2
Zaheer, R.S.3
Sanders, S.P.4
Proud, D.5
-
22
-
-
0030061283
-
Rhinovirus stimulation of interleukin-6 in vivo and in vitro Evidence for nuclear factor kappa B-dependent transcriptional activation
-
Zhu Z, Tang W, Ray A, Wu Y, Einarsson O, Landry ML, Gwaltney J Jr, Elias JA. Rhinovirus stimulation of interleukin-6 in vivo and in vitro. Evidence for nuclear factor kappa B-dependent transcriptional activation. J Clin Invest 1996;97:421-430.
-
(1996)
J Clin Invest
, vol.97
, pp. 421-430
-
-
Zhu, Z.1
Tang, W.2
Ray, A.3
Wu, Y.4
Einarsson, O.5
Landry, M.L.6
Gwaltney, J.7
Elias, J.A.8
-
23
-
-
33748446393
-
Role of deficient type III interferon-lambda production in asthma exacerbations
-
Contoli M, Message SD, Laza-Stanca V, Edwards MR, Wark PA, Bartlett NW, Kebadze T, Mallia P, Stanciu LA, Parker HL, et al. Role of deficient type III interferon-lambda production in asthma exacerbations. Nat Med 2006;12:1023-1026.
-
(2006)
Nat Med
, vol.12
, pp. 1023-1026
-
-
Contoli, M.1
Message, S.D.2
Laza-Stanca, V.3
Edwards, M.R.4
Wark, P.A.5
Bartlett, N.W.6
Kebadze, T.7
Mallia, P.8
Stanciu, L.A.9
Parker, H.L.10
-
24
-
-
53749103610
-
Rhinovirus infection and house dust mite exposure synergize in inducing bronchial epithelial cell interleukin-8 release
-
Bossios A, Gourgiotis D, Skevaki CL, Saxoni-Papageorgiou P, Lötvall J, Psarras S, Karpathios T, Constandopoulos AG, Johnston SL, Papadopoulos NG. Rhinovirus infection and house dust mite exposure synergize in inducing bronchial epithelial cell interleukin-8 release. Clin Exp Allergy 2008;38:1615-1626.
-
(2008)
Clin Exp Allergy
, vol.38
, pp. 1615-1626
-
-
Bossios, A.1
Gourgiotis, D.2
Skevaki, C.L.3
Saxoni-Papageorgiou, P.4
Lötvall, J.5
Psarras, S.6
Karpathios, T.7
Constandopoulos, A.G.8
Johnston, S.L.9
Papadopoulos, N.G.10
-
25
-
-
0037236826
-
IL-28 IL-29 and their class II cytokine receptor IL-28R
-
Sheppard P, Kindsvogel W, Xu W, Henderson K, Schlutsmeyer S, Whitmore TE, Kuestner R, Garrigues U, Birks C, Roraback J, et al. IL-28, IL-29 and their class II cytokine receptor IL-28R. Nat Immunol 2003;4:63-68.
-
(2003)
Nat Immunol
, vol.4
, pp. 63-68
-
-
Sheppard, P.1
Kindsvogel, W.2
Xu, W.3
Henderson, K.4
Schlutsmeyer, S.5
Whitmore, T.E.6
Kuestner, R.7
Garrigues, U.8
Birks, C.9
Roraback, J.10
-
26
-
-
2942579665
-
Double-stranded RNA activates RANTES gene transcription through co-operation of nuclear factor-kappaB and interferon regulatory factors in human airway epithelial cells
-
Ieki K, Matsukura S, Kokubu F, Kimura T, Kuga H, Kawaguchi M, Odaka M, Suzuki S, Watanabe S, Takeuchi H, et al. Double-stranded RNA activates RANTES gene transcription through co-operation of nuclear factor-kappaB and interferon regulatory factors in human airway epithelial cells. Clin Exp Allergy 2004;34:745-752.
-
(2004)
Clin Exp Allergy
, vol.34
, pp. 745-752
-
-
Ieki, K.1
Matsukura, S.2
Kokubu, F.3
Kimura, T.4
Kuga, H.5
Kawaguchi, M.6
Odaka, M.7
Suzuki, S.8
Watanabe, S.9
Takeuchi, H.10
-
28
-
-
65549165903
-
Interferons and viral infections
-
Fensterl V, Sen GC. Interferons and viral infections. Biofactors 2009;35: 14-20.
-
(2009)
Biofactors
, vol.35
, pp. 14-20
-
-
Fensterl, V.1
Sen, G.C.2
-
29
-
-
0033009888
-
Natural killer cells in antiviral defense: Function and regulation by innate cytokines
-
Biron CA, Nguyen KB, Pien GC, Cousens LP, Salazar-Mather TP. Natural killer cells in antiviral defense: function and regulation by innate cytokines. Annu Rev Immunol 1999;17:189-220.
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 189-220
-
-
Biron, C.A.1
Nguyen, K.B.2
Pien, G.C.3
Cousens, L.P.4
Salazar-Mather, T.P.5
-
30
-
-
17144403499
-
Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus
-
Wark PA, Johnston SL, Bucchieri F, Powell R, Puddicombe S, Laza-Stanca V, Holgate ST, Davies DE. Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus. J Exp Med 2005;201:937-947.
-
(2005)
J Exp Med
, vol.201
, pp. 937-947
-
-
Wark, P.A.1
Johnston, S.L.2
Bucchieri, F.3
Powell, R.4
Puddicombe, S.5
Laza-Stanca, V.6
Holgate, S.T.7
Davies, D.E.8
-
31
-
-
79955634439
-
Exogenous IFN-b has antiviral and anti-inflammatory properties in primary bronchial epithelial cells from asthmatic subjects exposed to rhinovirus
-
Cakebread JA, Xu Y, Grainge C, Kehagia V, Howarth PH, Holgate ST, Davies DE. Exogenous IFN-b has antiviral and anti-inflammatory properties in primary bronchial epithelial cells from asthmatic subjects exposed to rhinovirus. J Allergy Clin Immunol 2011;127: 1148-1154.e9.
-
(2011)
J Allergy Clin Immunol
, vol.127
, pp. 1148-1148e9
-
-
Cakebread, J.A.1
Xu, Y.2
Grainge, C.3
Kehagia, V.4
Howarth, P.H.5
Holgate, S.T.6
Davies, D.E.7
-
32
-
-
77249119309
-
Rhinovirus-induced modulation of gene expression in bronchial epithelial cells from subjects with asthma
-
Bochkov YA, Hanson KM, Keles S, Brockman-Schneider RA, Jarjour NN, Gern JE. Rhinovirus-induced modulation of gene expression in bronchial epithelial cells from subjects with asthma. Mucosal Immunol 2010;3:69-80.
-
(2010)
Mucosal Immunol
, vol.3
, pp. 69-80
-
-
Bochkov, Y.A.1
Hanson, K.M.2
Keles, S.3
Brockman-Schneider, R.A.4
Jarjour, N.N.5
Gern, J.E.6
-
33
-
-
67649210683
-
Vitro susceptibility to rhinovirus infection is greater for bronchial than for nasal airway epithelial cells in human subjects
-
Lopez-Souza N, Favoreto S, Wong H, Ward T, Yagi S, Schnurr D, Finkbeiner WE, Dolganov GM, Widdicombe JH, Boushey HA, et al. In vitro susceptibility to rhinovirus infection is greater for bronchial than for nasal airway epithelial cells in human subjects. J Allergy Clin Immunol 2009;123:1384-1390.e2.
-
(2009)
J Allergy Clin Immunol
, vol.123
, pp. 1384-1384e2
-
-
Lopez-Souza, N.1
Favoreto, S.2
Wong, H.3
Ward, T.4
Yagi, S.5
Schnurr, D.6
Finkbeiner, W.E.7
Dolganov, G.M.8
Widdicombe, J.H.9
Boushey, H.A.10
-
34
-
-
84893914123
-
Rhinovirus-induced interferon production is not deficient in well controlled asthma
-
Sykes A, Macintyre J, Edwards MR, Del Rosario A, Haas J, Gielen V, Kon OM, McHale M, Johnston SL. Rhinovirus-induced interferon production is not deficient in well controlled asthma. Thorax 2014;69: 240-246.
-
(2014)
Thorax
, vol.69
, pp. 240-246
-
-
Sykes, A.1
Macintyre, J.2
Edwards, M.R.3
Del Rosario, A.4
Haas, J.5
Gielen, V.6
Kon, O.M.7
McHale, M.8
Johnston, S.L.9
-
35
-
-
84879170291
-
TLR3 TLR4 and TLRs7-9 induced interferons are not impaired in airway and blood cells in well controlled asthma
-
Sykes A, Edwards MR, Macintyre J, Del Rosario A, Gielen V, Haas J, Kon OM, McHale M, Johnston SL. TLR3, TLR4 and TLRs7-9 induced interferons are not impaired in airway and blood cells in well controlled asthma. PLoS One 2013;8:e65921.
-
(2013)
PLoS One
, vol.8
, pp. e65921
-
-
Sykes, A.1
Edwards, M.R.2
Macintyre, J.3
Del Rosario, A.4
Gielen, V.5
Haas, J.6
Kon, O.M.7
McHale, M.8
Johnston, S.L.9
-
36
-
-
84879400685
-
Impaired innate interferon induction in severe therapy resistant atopic asthmatic children
-
Edwards MR, Regamey N, Vareille M, Kieninger E, Gupta A, Shoemark A, Saglani S, Sykes A, Macintyre J, Davies J, et al. Impaired innate interferon induction in severe therapy resistant atopic asthmatic children. Mucosal Immunol 2013;6:797-806.
-
(2013)
Mucosal Immunol
, vol.6
, pp. 797-806
-
-
Edwards, M.R.1
Regamey, N.2
Vareille, M.3
Kieninger, E.4
Gupta, A.5
Shoemark, A.6
Saglani, S.7
Sykes, A.8
Macintyre, J.9
Davies, J.10
-
37
-
-
84870291769
-
Deficient antiviral immune responses in childhood: Distinct roles of atopy and asthma
-
Baraldo S, Contoli M, Bazzan E, Turato G, Padovani A, Marku B, Calabrese F, Caramori G, Ballarin A, Snijders D, et al. Deficient antiviral immune responses in childhood: distinct roles of atopy and asthma. J Allergy Clin Immunol 2012;130:1307-1314.
-
(2012)
J Allergy Clin Immunol
, vol.130
, pp. 1307-1314
-
-
Baraldo, S.1
Contoli, M.2
Bazzan, E.3
Turato, G.4
Padovani, A.5
Marku, B.6
Calabrese, F.7
Caramori, G.8
Ballarin, A.9
Snijders, D.10
-
38
-
-
84923315952
-
Asthma is associated with multiple alterations in anti-viral innate signalling pathways
-
Pritchard AL, White OJ, Burel JG, Carroll ML, Phipps S, Upham JW. Asthma is associated with multiple alterations in anti-viral innate signalling pathways. PLoS One 2014;9:e106501.
-
(2014)
PLoS One
, vol.9
, pp. e106501
-
-
Pritchard, A.L.1
White, O.J.2
Burel, J.G.3
Carroll, M.L.4
Phipps, S.5
Upham, J.W.6
-
39
-
-
84861654883
-
Rhinovirus 16-induced IFN-A and IFN-b are deficient in bronchoalveolar lavage cells in asthmatic patients
-
Sykes A, Edwards MR, Macintyre J, del Rosario A, Bakhsoliani E, Trujillo-Torralbo MB, Kon OM, Mallia P, McHale M, Johnston SL. Rhinovirus 16-induced IFN-A and IFN-b are deficient in bronchoalveolar lavage cells in asthmatic patients. J Allergy Clin Immunol 2012;129:1506-1514.e6.
-
(2012)
J Allergy Clin Immunol
, vol.129
, pp. 1506-1506e6
-
-
Sykes, A.1
Edwards, M.R.2
Macintyre, J.3
Del Rosario, A.4
Bakhsoliani, E.5
Trujillo-Torralbo, M.B.6
Kon, O.M.7
Mallia, P.8
McHale, M.9
Johnston, S.L.10
-
40
-
-
84906932841
-
The effect of inhaled IFN-b on worsening of asthma symptoms caused by viral infections. A randomized trial
-
INTERCIA Study Group
-
DjukanovićR, Harrison T, Johnston SL, Gabbay F, Wark P, Thomson NC, Niven R, Singh D, Reddel HK, Davies DE, et al.; INTERCIA Study Group. The effect of inhaled IFN-b on worsening of asthma symptoms caused by viral infections. A randomized trial. Am J Respir Crit Care Med 2014;190:145-154.
-
(2014)
Am J Respir Crit Care Med
, vol.190
, pp. 145-154
-
-
Djukanović, R.1
Harrison, T.2
Johnston, S.L.3
Gabbay, F.4
Wark, P.5
Thomson, N.C.6
Niven, R.7
Singh, D.8
Reddel, H.K.9
Davies, D.E.10
-
41
-
-
77953530680
-
Regulated gene expression in cultured type II cells of adult human lung
-
Ballard PL, Lee JW, Fang X, Chapin C, Allen L, Segal MR, Fischer H, Illek B, Gonzales LW, Kolla V, et al. Regulated gene expression in cultured type II cells of adult human lung. Am J Physiol Lung Cell Mol Physiol 2010;299:L36-L50.
-
(2010)
Am J Physiol Lung Cell Mol Physiol
, vol.299
, pp. L36-L50
-
-
Ballard, P.L.1
Lee, J.W.2
Fang, X.3
Chapin, C.4
Allen, L.5
Segal, M.R.6
Fischer, H.7
Illek, B.8
Gonzales, L.W.9
Kolla, V.10
-
42
-
-
0037504020
-
Subepithelial basement membrane immunoreactivity for matrix metalloproteinase 9: Association with asthma severity, neutrophilic inflammation, and wound repair
-
Wenzel SE, Balzar S, Cundall M, Chu HW. Subepithelial basement membrane immunoreactivity for matrix metalloproteinase 9: Association with asthma severity, neutrophilic inflammation, and wound repair. J Allergy Clin Immunol 2003;111:1345-1352.
-
(2003)
J Allergy Clin Immunol
, vol.111
, pp. 1345-1352
-
-
Wenzel, S.E.1
Balzar, S.2
Cundall, M.3
Chu, H.W.4
-
43
-
-
37349091262
-
Effect of ADRB2 polymorphisms on response to longacting beta2-Agonist therapy: A pharmacogenetic analysis of two randomised studies
-
Bleecker ER, Postma DS, Lawrance RM, Meyers DA, Ambrose HJ, Goldman M. Effect of ADRB2 polymorphisms on response to longacting beta2-Agonist therapy: A pharmacogenetic analysis of two randomised studies. Lancet 2007;370:2118-2125.
-
(2007)
Lancet
, vol.370
, pp. 2118-2125
-
-
Bleecker, E.R.1
Postma, D.S.2
Lawrance, R.M.3
Meyers, D.A.4
Ambrose, H.J.5
Goldman, M.6
-
44
-
-
58849139194
-
Long-Acting beta-Agonists: A review of formoterol safety data from asthma clinical trials
-
Sears MR, Ottosson A, Radner F, Suissa S. Long-Acting beta-Agonists: A review of formoterol safety data from asthma clinical trials. Eur Respir J 2009;33:21-32.
-
(2009)
Eur Respir J
, vol.33
, pp. 21-32
-
-
Sears, M.R.1
Ottosson, A.2
Radner, F.3
Suissa, S.4
-
45
-
-
34247265510
-
Functional polymorphism in the suppressor of cytokine signaling 1 gene associated with adult asthma
-
Harada M, Nakashima K, Hirota T, Shimizu M, Doi S, Fujita K, Shirakawa T, Enomoto T, Yoshikawa M, Moriyama H, et al. Functional polymorphism in the suppressor of cytokine signaling 1 gene associated with adult asthma. Am J Respir Cell Mol Biol 2007; 36:491-496.
-
(2007)
Am J Respir Cell Mol Biol
, vol.36
, pp. 491-496
-
-
Harada, M.1
Nakashima, K.2
Hirota, T.3
Shimizu, M.4
Doi, S.5
Fujita, K.6
Shirakawa, T.7
Enomoto, T.8
Yoshikawa, M.9
Moriyama, H.10
-
46
-
-
0042967672
-
SOCS-3 regulates onset and maintenance of T(H)2-mediated allergic responses
-
Seki Y, Inoue H, Nagata N, Hayashi K, Fukuyama S, Matsumoto K, Komine O, Hamano S, Himeno K, Inagaki-Ohara K, et al. SOCS-3 regulates onset and maintenance of T(H)2-mediated allergic responses. Nat Med 2003;9:1047-1054.
-
(2003)
Nat Med
, vol.9
, pp. 1047-1054
-
-
Seki, Y.1
Inoue, H.2
Nagata, N.3
Hayashi, K.4
Fukuyama, S.5
Matsumoto, K.6
Komine, O.7
Hamano, S.8
Himeno, K.9
Inagaki-Ohara, K.10
-
47
-
-
84949117566
-
Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons
-
Gielen V, Sykes V, Zhu J, Chan B, Macintyre J, Regamey N, Kieninger E, Gupta A, Shoemark A, Bossley C, et al. Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons. J Allergy Clin Immunol 2015;136:177-188.e11.
-
(2015)
J Allergy Clin Immunol
, vol.136
, pp. 177-177e11
-
-
Gielen, V.1
Sykes, V.2
Zhu, J.3
Chan, B.4
Macintyre, J.5
Regamey, N.6
Kieninger, E.7
Gupta, A.8
Shoemark, A.9
Bossley, C.10
-
48
-
-
84866126983
-
Transforming growth factor-beta promotes rhinovirus replication in bronchial epithelial cells by suppressing the innate immune response
-
Bedke N, Sammut D, Green B, Kehagia V, Dennison P, Jenkins G, Tatler A, Howarth PH, Holgate ST, Davies DE. Transforming growth factor-beta promotes rhinovirus replication in bronchial epithelial cells by suppressing the innate immune response. PLoS One 2012; 7:e44580.
-
(2012)
PLoS One
, vol.7
, pp. e44580
-
-
Bedke, N.1
Sammut, D.2
Green, B.3
Kehagia, V.4
Dennison, P.5
Jenkins, G.6
Tatler, A.7
Howarth, P.H.8
Holgate, S.T.9
Davies, D.E.10
-
49
-
-
69449100311
-
Transforming growth factor-beta enhances rhinovirus infection by diminishing early innate responses
-
Thomas BJ, Lindsay M, Dagher H, Freezer NJ, Li D, Ghildyal R, Bardin PG. Transforming growth factor-beta enhances rhinovirus infection by diminishing early innate responses. Am J Respir Cell Mol Biol 2009;41:339-347.
-
(2009)
Am J Respir Cell Mol Biol
, vol.41
, pp. 339-347
-
-
Thomas, B.J.1
Lindsay, M.2
Dagher, H.3
Freezer, N.J.4
Li, D.5
Ghildyal, R.6
Bardin, P.G.7
-
50
-
-
84879516877
-
Interaction between allergy and innate immunity: Model for eosinophil regulation of epithelial cell interferon expression
-
Mathur SK, Fichtinger PS, Kelly JT, Lee WM, Gern JE, Jarjour NN. Interaction between allergy and innate immunity: model for eosinophil regulation of epithelial cell interferon expression. Ann Allergy Asthma Immunol 2013;111:25-31.
-
(2013)
Ann Allergy Asthma Immunol
, vol.111
, pp. 25-31
-
-
Mathur, S.K.1
Fichtinger, P.S.2
Kelly, J.T.3
Lee, W.M.4
Gern, J.E.5
Jarjour, N.N.6
-
51
-
-
84884540824
-
Interleukin-1 receptor-Associated kinase M (IRAK-M) promotes human rhinovirus infection in lung epithelial cells via the autophagic pathway
-
Wu Q, van Dyk LF, Jiang D, Dakhama A, Li L, White SR, Gross A, Chu HW. Interleukin-1 receptor-Associated kinase M (IRAK-M) promotes human rhinovirus infection in lung epithelial cells via the autophagic pathway. Virology 2013;446:199-206.
-
(2013)
Virology
, vol.446
, pp. 199-206
-
-
Wu, Q.1
Van Dyk, L.F.2
Jiang, D.3
Dakhama, A.4
Li, L.5
White, S.R.6
Gross, A.7
Chu, H.W.8
-
52
-
-
79151476446
-
IL-13 suppresses double-stranded RNA-induced IFN-l production in lung cells
-
Moriwaki A, Matsumoto K, Matsunaga Y, Fukuyama S, Matsumoto T, Kan-o K, Noda N, Asai Y, Nakanishi Y, Inoue H. IL-13 suppresses double-stranded RNA-induced IFN-l production in lung cells. Biochem Biophys Res Commun 2011;404:922-927.
-
(2011)
Biochem Biophys Res Commun
, vol.404
, pp. 922-927
-
-
Moriwaki, A.1
Matsumoto, K.2
Matsunaga, Y.3
Fukuyama, S.4
Matsumoto, T.5
Kan-O, K.6
Noda, N.7
Asai, Y.8
Nakanishi, Y.9
Inoue, H.10
-
53
-
-
84938199992
-
Th2 cytokines impair innate immune responses to rhinovirus in respiratory epithelial cells
-
Contoli, M., Ito K, Padovani A, Poletti D, Marku B, Edwards MR, Stanciu LA, Gnesini G, Pastore A, Spanevello A, et al., Th2 cytokines impair innate immune responses to rhinovirus in respiratory epithelial cells. Allergy 2015;70:910-920.
-
(2015)
Allergy
, vol.70
, pp. 910-920
-
-
Contoli, M.1
Ito, K.2
Padovani, A.3
Poletti, D.4
Marku, B.5
Edwards, M.R.6
Stanciu, L.A.7
Gnesini, G.8
Pastore, A.9
Spanevello, A.10
-
54
-
-
81355136055
-
Budesonide and formoterol reduce early innate anti-viral immune responses in vitro
-
Davies JM, Carroll ML, Li H, Poh AM, Kirkegard D, Towers M, Upham JW. Budesonide and formoterol reduce early innate anti-viral immune responses in vitro. PLoS One 2011; 6:e27898.
-
(2011)
PLoS One
, vol.6
, pp. e27898
-
-
Davies, J.M.1
Carroll, M.L.2
Li, H.3
Poh, A.M.4
Kirkegard, D.5
Towers, M.6
Upham, J.W.7
-
55
-
-
84925263127
-
Glucocorticosteroids enhance replication of respiratory viruses: Effect of adjuvant interferon
-
Thomas BJ, Porritt RA, Hertzog PJ, Bardin PG, Tate MD. Glucocorticosteroids enhance replication of respiratory viruses: effect of adjuvant interferon. Sci Rep 2014;4:7176.
-
(2014)
Sci Rep
, vol.4
, pp. 7176
-
-
Thomas, B.J.1
Porritt, R.A.2
Hertzog, P.J.3
Bardin, P.G.4
Tate, M.D.5
-
56
-
-
84919339989
-
IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo
-
Jackson DJ, Makrinioti H, Rana BM, Shamji BW, Trujillo-Torralbo MB, Footitt J, Jerico Del-Rosario, Telcian AG, Nikonova A, Zhu J, et al. IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo. Am J Respir Crit Care Med 2014;190: 1373-1382.
-
(2014)
Am J Respir Crit Care Med
, vol.190
, pp. 1373-1382
-
-
Jackson, D.J.1
Makrinioti, H.2
Rana, B.M.3
Shamji, B.W.4
Trujillo-Torralbo, M.B.5
Footitt, J.6
Del-Rosario, J.7
Telcian, A.G.8
Nikonova, A.9
Zhu, J.10
-
57
-
-
84908374296
-
Rhinovirusinduced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation
-
Beale J, Jayaraman A, Jackson DJ, Macintyre JD, Edwards MR, Walton RP, Zhu J, Ching YM, Shamji B, Edwards M, et al. Rhinovirusinduced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation. Sci Transl Med 2014;6:256ra134.
-
(2014)
Sci Transl Med
, vol.6
, pp. 256ra134
-
-
Beale, J.1
Jayaraman, A.2
Jackson, D.J.3
Macintyre, J.D.4
Edwards, M.R.5
Walton, R.P.6
Zhu, J.7
Ching, Y.M.8
Shamji, B.9
Edwards, M.10
-
58
-
-
80155144555
-
CXCL10 and its receptor CXCR3 regulate synovial fibroblast invasion in rheumatoid arthritis
-
Laragione T, Brenner M, Sherry B, Gulko PS. CXCL10 and its receptor CXCR3 regulate synovial fibroblast invasion in rheumatoid arthritis. Arthritis Rheum 2011;63:3274-3283.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 3274-3283
-
-
Laragione, T.1
Brenner, M.2
Sherry, B.3
Gulko, P.S.4
-
59
-
-
84861816840
-
A phase II, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of MDX-1100, a fully human anti-CXCL10 monoclonal antibody, in combination with methotrexate in patients with rheumatoid arthritis
-
Yellin M, Paliienko I, Balanescu A, Ter-Vartanian S, Tseluyko V, Xu LA, Tao X, Cardarelli PM, Leblanc H, Nichol G, et al. A phase II, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of MDX-1100, a fully human anti-CXCL10 monoclonal antibody, in combination with methotrexate in patients with rheumatoid arthritis. Arthritis Rheum 2012;64: 1730-1739.
-
(2012)
Arthritis Rheum
, vol.64
, pp. 1730-1739
-
-
Yellin, M.1
Paliienko, I.2
Balanescu, A.3
Ter-Vartanian, S.4
Tseluyko, V.5
Xu, L.A.6
Tao, X.7
Cardarelli, P.M.8
Leblanc, H.9
Nichol, G.10
-
60
-
-
84891847947
-
Targeting interleukin-6 in inflammatory autoimmune diseases and cancers
-
Yao X, Huang J, Zhong H, Shen N, Faggioni R, Fung M, Yao Y. Targeting interleukin-6 in inflammatory autoimmune diseases and cancers. Pharmacol Ther 2014;141:125-139.
-
(2014)
Pharmacol Ther
, vol.141
, pp. 125-139
-
-
Yao, X.1
Huang, J.2
Zhong, H.3
Shen, N.4
Faggioni, R.5
Fung, M.6
Yao, Y.7
-
61
-
-
62549084077
-
A randomized double-blind placebo-controlled study of tumor necrosis factor-Alpha blockade in severe persistent asthma
-
T03 Asthma Investigators
-
Wenzel SE, Barnes PJ, Bleecker ER, Bousquet J, Busse W, Dahlén SE, Holgate ST, Meyers DA, Rabe KF, Antczak A, et al.; T03 Asthma Investigators. A randomized, double-blind, placebo-controlled study of tumor necrosis factor-Alpha blockade in severe persistent asthma. Am J Respir Crit Care Med 2009;179:549-558.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. 549-558
-
-
Wenzel, S.E.1
Barnes, P.J.2
Bleecker, E.R.3
Bousquet, J.4
Busse, W.5
Dahlén, S.E.6
Holgate, S.T.7
Meyers, D.A.8
Rabe, K.F.9
Antczak, A.10
-
62
-
-
0038548251
-
Efficacy and safety of oral pleconaril for treatment of colds due to picornaviruses in adults: Results of 2 double-blind randomized placebo-controlled trials
-
Pleconaril Respiratory Infection Study Group
-
Hayden FG, Herrington DT, Coats TL, Kim K, Cooper EC, Villano SA, Liu S, Hudson S, Pevear DC, Collett M, et al.; Pleconaril Respiratory Infection Study Group. Efficacy and safety of oral pleconaril for treatment of colds due to picornaviruses in adults: results of 2 double-blind, randomized, placebo-controlled trials. Clin Infect Dis 2003;36:1523-1532.
-
(2003)
Clin Infect Dis
, vol.36
, pp. 1523-1532
-
-
Hayden, F.G.1
Herrington, D.T.2
Coats, T.L.3
Kim, K.4
Cooper, E.C.5
Villano, S.A.6
Liu, S.7
Hudson, S.8
Pevear, D.C.9
Collett, M.10
-
63
-
-
83955164248
-
Combating enterovirus replication: State-of-The-Art on antiviral research
-
Thibaut HJ, De Palma AM, Neyts J. Combating enterovirus replication: state-of-The-Art on antiviral research. Biochem Pharmacol 2012;83: 185-192.
-
(2012)
Biochem Pharmacol
, vol.83
, pp. 185-192
-
-
Thibaut, H.J.1
De Palma, A.M.2
Neyts, J.3
-
64
-
-
84884678019
-
Crossserotype immunity induced by immunization with a conserved rhinovirus capsid protein
-
Glanville N, McLean GR, Guy B, Lecouturier V, Berry C, Girerd Y, Gregoire C, Walton RP, Pearson RM, Kebadze T, et al. Crossserotype immunity induced by immunization with a conserved rhinovirus capsid protein. PLoS Pathog 2013;9:e1003669.
-
(2013)
PLoS Pathog
, vol.9
, pp. e1003669
-
-
Glanville, N.1
McLean, G.R.2
Guy, B.3
Lecouturier, V.4
Berry, C.5
Girerd, Y.6
Gregoire, C.7
Walton, R.P.8
Pearson, R.M.9
Kebadze, T.10
-
65
-
-
77953404932
-
Counterregulation between the FcepsilonRI pathway and antiviral responses in human plasmacytoid dendritic cells
-
Gill MA, Bajwa G, George TA, Dong CC, Dougherty II, Jiang N, Gan VN, Gruchalla RS. Counterregulation between the FcepsilonRI pathway and antiviral responses in human plasmacytoid dendritic cells. J Immunol 2010;184:5999-6006.
-
(2010)
J Immunol
, vol.184
, pp. 5999-6006
-
-
Gill, M.A.1
Bajwa, G.2
George, T.A.3
Dong, C.C.4
Dougherty, I.I.5
Jiang, N.6
Gan, V.N.7
Gruchalla, R.S.8
-
66
-
-
77955300029
-
Double-stranded RNA induces disproportionate expression of thymic stromal lymphopoietin versus interferon-beta in bronchial epithelial cells from donors with asthma
-
Uller L, Leino M, Bedke N, Sammut D, Green B, Lau L, Howarth PH, Holgate ST, Davies DE. Double-stranded RNA induces disproportionate expression of thymic stromal lymphopoietin versus interferon-beta in bronchial epithelial cells from donors with asthma. Thorax 2010;65:626-632.
-
(2010)
Thorax
, vol.65
, pp. 626-632
-
-
Uller, L.1
Leino, M.2
Bedke, N.3
Sammut, D.4
Green, B.5
Lau, L.6
Howarth, P.H.7
Holgate, S.T.8
Davies, D.E.9
-
67
-
-
84890809832
-
TLR3 and MDA5 signalling, although not expression, is impaired in asthmatic epithelial cells in response to rhinovirus infection
-
Parsons KS, Hsu AC, Wark PA. TLR3 and MDA5 signalling, although not expression, is impaired in asthmatic epithelial cells in response to rhinovirus infection. Clin Exp Allergy 2014;44:91-101.
-
(2014)
Clin Exp Allergy
, vol.44
, pp. 91-101
-
-
Parsons, K.S.1
Hsu, A.C.2
Wark, P.A.3
-
68
-
-
84899774977
-
Viral and host factors determine innate immune responses in airway epithelial cells from children with wheeze and atopy
-
Spann KM, Baturcam E, Schagen J, Jones C, Straub CP, Preston FM, Chen L, Phipps S, Sly PD, Fantino E. Viral and host factors determine innate immune responses in airway epithelial cells from children with wheeze and atopy. Thorax 2014;69:918-925.
-
(2014)
Thorax
, vol.69
, pp. 918-925
-
-
Spann, K.M.1
Baturcam, E.2
Schagen, J.3
Jones, C.4
Straub, C.P.5
Preston, F.M.6
Chen, L.7
Phipps, S.8
Sly, P.D.9
Fantino, E.10
-
69
-
-
84892981475
-
DsRNA-induced changes in gene expression profiles of primary nasal and bronchial epithelial cells from patients with asthma rhinitis and controls
-
Wagener AH, Zwinderman AH, Luiten S, Fokkens WJ, Bel EH, Sterk PJ, van Drunen CM. dsRNA-induced changes in gene expression profiles of primary nasal and bronchial epithelial cells from patients with asthma, rhinitis and controls. Respir Res 2014;15:9-9.
-
(2014)
Respir Res
, vol.15
, pp. 9
-
-
Wagener, A.H.1
Zwinderman, A.H.2
Luiten, S.3
Fokkens, W.J.4
Bel, E.H.5
Sterk, P.J.6
Van Drunen, C.M.7
-
70
-
-
84919633225
-
Interferon response and respiratory virus control are preserved in bronchial epithelial cells in asthma
-
Patel DA, You Y, Huang G, Byers DE, Kim HJ, Agapov E, Moore ML, Peebles RS Jr, Castro M, Sumino K, et al. Interferon response and respiratory virus control are preserved in bronchial epithelial cells in asthma. J Allergy Clin Immunol 2014;134:1402-1412.e7.
-
(2014)
J Allergy Clin Immunol
, vol.134
, pp. 1402-1402e7
-
-
Patel, D.A.1
You, Y.2
Huang, G.3
Byers, D.E.4
Kim, H.J.5
Agapov, E.6
Moore, M.L.7
Peebles, R.S.8
Castro, M.9
Sumino, K.10
-
71
-
-
0034907372
-
Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma
-
Busse W, Corren J, Lanier BQ, McAlary M, Fowler-Taylor A, Cioppa GD, van As A, Gupta N. Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma. J Allergy Clin Immunol 2001;108:184-190.
-
(2001)
J Allergy Clin Immunol
, vol.108
, pp. 184-190
-
-
Busse, W.1
Corren, J.2
Lanier, B.Q.3
McAlary, M.4
Fowler-Taylor, A.5
Cioppa, G.D.6
Van As, A.7
Gupta, N.8
-
72
-
-
0034881877
-
The anti-IgE antibody omalizumab reduces exacerbations and steroid requirement in allergic asthmatics
-
Solè r M, Matz J, Townley R, Buhl R, OBrien J, Fox H, Thirlwell J, Gupta N, Della Cioppa G. The anti-IgE antibody omalizumab reduces exacerbations and steroid requirement in allergic asthmatics. Eur Respir J 2001;18:254-261.
-
(2001)
Eur Respir J
, vol.18
, pp. 254-261
-
-
Solèr, M.1
Matz, J.2
Townley, R.3
Buhl, R.4
Obrien, J.5
Fox, H.6
Thirlwell, J.7
Gupta, N.8
Della Cioppa, G.9
-
73
-
-
84865145614
-
Mepolizumab for severe eosinophilic asthma (DREAM): A multicentre, double-blind, placebo-controlled trial
-
Pavord ID, Korn S, Howarth P, Bleecker ER, Buhl R, Keene ON, Ortega H, Chanez P. Mepolizumab for severe eosinophilic asthma (DREAM): A multicentre, double-blind, placebo-controlled trial. Lancet 2012; 380:651-659.
-
(2012)
Lancet
, vol.380
, pp. 651-659
-
-
Pavord, I.D.1
Korn, S.2
Howarth, P.3
Bleecker, E.R.4
Buhl, R.5
Keene, O.N.6
Ortega, H.7
Chanez, P.8
-
74
-
-
84919382915
-
Benralizumab, an antiinterleukin 5 receptor a monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: A phase 2b randomised doseranging study
-
Castro M, Wenzel SE, Bleecker ER, Pizzichini E, Kuna P, Busse WW, Gossage DL, Ward CK, Wu Y, Wang B, et al. Benralizumab, an antiinterleukin 5 receptor a monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: A phase 2b randomised doseranging study. Lancet Respir Med 2014;2:879-890.
-
(2014)
Lancet Respir Med
, vol.2
, pp. 879-890
-
-
Castro, M.1
Wenzel, S.E.2
Bleecker, E.R.3
Pizzichini, E.4
Kuna, P.5
Busse, W.W.6
Gossage, D.L.7
Ward, C.K.8
Wu, Y.9
Wang, B.10
-
75
-
-
61849086181
-
Mepolizumab and exacerbations of refractory eosinophilic asthma
-
Haldar P, Brightling CE, Hargadon B, Gupta S, Monteiro W, Sousa A, Marshall RP, Bradding P, Green RH, Wardlaw AJ, et al. Mepolizumab and exacerbations of refractory eosinophilic asthma. N Engl J Med 2009;360:973-984.
-
(2009)
N Engl J Med
, vol.360
, pp. 973-984
-
-
Haldar, P.1
Brightling, C.E.2
Hargadon, B.3
Gupta, S.4
Monteiro, W.5
Sousa, A.6
Marshall, R.P.7
Bradding, P.8
Green, R.H.9
Wardlaw, A.J.10
-
76
-
-
80053084755
-
Lebrikizumab treatment in adults with asthma
-
Corren J, Lemanske RF, Hanania NA, Korenblat PE, Parsey MV, Arron JR, Harris JM, Scheerens H, Wu LC, Su Z, et al. Lebrikizumab treatment in adults with asthma. N Engl J Med 2011;365: 1088-1098.
-
(2011)
N Engl J Med
, vol.365
, pp. 1088-1098
-
-
Corren, J.1
Lemanske, R.F.2
Hanania, N.A.3
Korenblat, P.E.4
Parsey, M.V.5
Arron, J.R.6
Harris, J.M.7
Scheerens, H.8
Wu, L.C.9
Su, Z.10
-
77
-
-
84879401471
-
Dupilumab in persistent asthma with elevated eosinophil levels
-
Wenzel S, Ford L, Pearlman D, Spector S, Sher L, Skobieranda F, Wang L, Kirkesseli S, Rocklin R, Bock B, et al. Dupilumab in persistent asthma with elevated eosinophil levels. N Engl J Med 2013;368: 2455-2466.
-
(2013)
N Engl J Med
, vol.368
, pp. 2455-2466
-
-
Wenzel, S.1
Ford, L.2
Pearlman, D.3
Spector, S.4
Sher, L.5
Skobieranda, F.6
Wang, L.7
Kirkesseli, S.8
Rocklin, R.9
Bock, B.10
|