Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation

Science Translational Medicine

Volumn 6, Issue 256, 2014, Pages

  Beale, Janine ^a,b,c   Jayaraman, Annabelle ^a,b,c   Jackson, David J ^a,b,c,d   Macintyre, Jonathan D R ^a,b,c,d   Edwards, Michael R ^a,b   Walton, Ross P ^a,b,c   Zhu, Jie ^a,b,c   Ching, Yee Man ^a,b,c   Shamji, Betty ^e   Edwards, Matt ^e   Westwick, John ^e   Cousins, David J ^b,f   Hwang, You Yi ^g   McKenzie, Andrew ^g   Johnston, Sebastian L ^a,b,c,d   Bartlett, Nathan W ^a,b,c  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d IMPERIAL COLLEGE HEALTHCARE NHS TRUST   (United Kingdom)

^e NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^f KING'S COLLEGE LONDON   (United Kingdom)

^g MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 25; INTERLEUKIN 17; INTERLEUKIN 17 RECEPTOR;

ADAPTIVE IMMUNITY; ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASOPHIL; BRONCHUS MUCOSA; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE EXACERBATION; EOSINOPHIL; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INNATE IMMUNITY; MOUSE; MUCUS SECRETION; NONHUMAN; PROTEIN EXPRESSION; RESPIRATORY TRACT ALLERGY; RHINOVIRUS; RHINOVIRUS INFECTION; T LYMPHOCYTE; VIRUS IMMUNITY; VIRUS LOAD; ANTAGONISTS AND INHIBITORS; ASTHMA; BIOSYNTHESIS; CELL CULTURE; HYPERSENSITIVITY; IMMUNOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PICORNAVIRUS INFECTION; VIROLOGY; VIRUS PNEUMONIA;

ASTHMA; CELLS, CULTURED; HUMANS; HYPERSENSITIVITY; INTERLEUKIN-17; PICORNAVIRIDAE INFECTIONS; PNEUMONIA, VIRAL; RECEPTORS, INTERLEUKIN-17; RHINOVIRUS; T-LYMPHOCYTES;

EID: 84908374296     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3009124     Document Type: Article

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