Transforming Growth Factor-Beta Promotes Rhinovirus Replication in Bronchial Epithelial Cells by Suppressing the Innate Immune Response

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Bedke, Nicole ^a   Sammut, David ^a   Green, Ben ^a   Kehagia, Valia ^a   Dennison, Patrick ^a,b   Jenkins, Gisli ^c   Tatler, Amanda ^c   Howarth, Peter H ^a,b   Holgate, Stephen T ^a,b   Davies, Donna E ^a,b  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b University Hospital Southampton NHS Foundation Trust   (United Kingdom)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED RNA; INTERFERON; NEUTRALIZING ANTIBODY; SMAD2 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; SUPPRESSOR OF CYTOKINE SIGNALING 2; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA2;

ARTICLE; ASTHMA; BRONCHUS MUCOSA; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOKINE RESPONSE; DISEASE EXACERBATION; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; INNATE IMMUNITY; PROTEIN EXPRESSION; RHINOVIRUS; RHINOVIRUS INFECTION; VIRUS REPLICATION;

ANTIBODIES, NEUTRALIZING; BLOTTING, WESTERN; BRONCHI; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; HUMANS; IMMUNITY, INNATE; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHINOVIRUS; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRANSFORMING GROWTH FACTOR BETA; VIRUS REPLICATION;

RHINOVIRUS;

EID: 84866126983     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044580     Document Type: Article

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