-
1
-
-
84867021989
-
Transcriptional amplification in tumor cells with elevated c-Myc
-
23021215
-
Lin CY, Loven J, Rahl PB, Paranal RM, Burge CB, Bradner JE, Lee TI, Young RA. Transcriptional amplification in tumor cells with elevated c-Myc. Cell 2012; 151:56-67; PMID:23021215; http://dx.doi.org/10.1016/j.cell.2012.08.026
-
(2012)
Cell
, vol.151
, pp. 56-67
-
-
Lin, C.Y.1
Loven, J.2
Rahl, P.B.3
Paranal, R.M.4
Burge, C.B.5
Bradner, J.E.6
Lee, T.I.7
Young, R.A.8
-
2
-
-
84867010006
-
C-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells
-
23021216
-
Nie Z, Hu G, Wei G, Cui K, Yamane A, Resch W, Wang R, Green DR, Tessarollo L, Casellas R, et al. c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells. Cell 2012; 151:68-79; PMID:23021216; http://dx.doi.org/10.1016/j-cell.2012.08.033
-
(2012)
Cell
, vol.151
, pp. 68-79
-
-
Nie, Z.1
Hu, G.2
Wei, G.3
Cui, K.4
Yamane, A.5
Resch, W.6
Wang, R.7
Green, D.R.8
Tessarollo, L.9
Casellas, R.10
-
3
-
-
84904785973
-
Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis
-
25043028
-
Sabo A, Kress TR, Pelizzola M, de Pretis S, Gorski MM, Tesi A, Morelli MJ, Bora P, Doni M, Verrecchia A, et al. Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis. Nature 2014; 511: 488-492; PMID:25043028; http://dx.doi.org/10.1038/nature13537
-
(2014)
Nature
, vol.511
, pp. 488-492
-
-
Sabo, A.1
Kress, T.R.2
Pelizzola, M.3
De Pretis, S.4
Gorski, M.M.5
Tesi, A.6
Morelli, M.J.7
Bora, P.8
Doni, M.9
Verrecchia, A.10
-
4
-
-
84904823447
-
Activation and repression by onco-genic MYC shape tumour-specific gene expression profiles
-
25043018
-
Walz S, Lorenzin F, Morton J, Wiese KE, von Eyss B, Herold S, Rycak L, Dumay-Odelot H, Karim S, Bartkuhn M, et al. Activation and repression by onco-genic MYC shape tumour-specific gene expression profiles. Nature 2014; 511:483-487; PMID:25043018; http://dx.doi.org/10.1038/nature13473
-
(2014)
Nature
, vol.511
, pp. 483-487
-
-
Walz, S.1
Lorenzin, F.2
Morton, J.3
Wiese, K.E.4
Von Eyss, B.5
Herold, S.6
Rycak, L.7
Dumay-Odelot, H.8
Karim, S.9
Bartkuhn, M.10
-
5
-
-
23144464363
-
Transcriptional regulation and transformation by Myc proteins
-
16064138
-
Adhikary S, Eilers M. Transcriptional regulation and transformation by Myc proteins. Nat Rev Mol Cell Biol 2005; 6:635-645; PMID:16064138; http://dx.doi.org/doi:10.1038/nrm1703
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 635-645
-
-
Adhikary, S.1
Eilers, M.2
-
6
-
-
56749184298
-
Reflecting on 25 years with MYC
-
19029958
-
Meyer N, Penn LZ. Reflecting on 25 years with MYC. Nat Rev Cancer 2008; 8:976-990; PMID:19029958; http://dx.doi.org/10.1038/nrc2231
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 976-990
-
-
Meyer, N.1
Penn, L.Z.2
-
7
-
-
77949920493
-
MYC as a regulator of ribosome biogenesis and protein synthesis
-
19029958
-
van Riggelen J, Yetil A, Felsher DW. MYC as a regulator of ribosome biogenesis and protein synthesis. Nat Rev Cancer 2010; 10: 301-309; PMID:19029958; http://dx.doi.org/10.1038/nrc2231
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 301-309
-
-
Van Riggelen, J.1
Yetil, A.2
Felsher, D.W.3
-
8
-
-
0033551374
-
MYC onco-genes and human neoplastic disease
-
20332779
-
Nesbit CE, Tersak JM, aProchownik EV. MYC onco-genes and human neoplastic disease. Oncogene 1999; 18:3004-3016; PMID:20332779; http://dx.doi.org/10.1038/nrc2819
-
(1999)
Oncogene
, vol.18
, pp. 3004-3016
-
-
Nesbit, C.E.1
Tersak, J.M.2
Aprochownik, E.V.3
-
10
-
-
33748138585
-
Role of post-translational modifications in regulating c-Myc proteolysis, transcriptional activity and biological function
-
16938463, PMID:16938463
-
Hann SR. Role of post-translational modifications in regulating c-Myc proteolysis, transcriptional activity and biological function. Semin Cancer Biol 2006; 16:288-302; PMID:16938463; http://dx.doi.org/10.1016/j.semcancer.2006.08.004; PMID:16938463
-
(2006)
Semin Cancer Biol
, vol.16
, pp. 288-302
-
-
Hann, S.R.1
-
11
-
-
0033082892
-
Ras enhances Myc protein stability
-
10078200
-
Sears R, Leone G, DeGregori J, Nevins JR. Ras enhances Myc protein stability. Mol Cell 1999; 3:169-179; PMID:10078200; http://dx.doi.org/10.1016/S1097-2765(00)80308-1
-
(1999)
Mol Cell
, vol.3
, pp. 169-179
-
-
Sears, R.1
Leone, G.2
Degregori, J.3
Nevins, J.R.4
-
12
-
-
0034306997
-
Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability
-
11018017
-
Sears R, Nuckolls F, Haura E, Taya Y, Tamai K, Nevins JR. Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability. Genes Dev 2000;14:2501-2514; PMID:11018017; http://dx.doi.org/10.1101/gad.836800
-
(2000)
Genes Dev
, vol.14
, pp. 2501-2514
-
-
Sears, R.1
Nuckolls, F.2
Haura, E.3
Taya, Y.4
Tamai, K.5
Nevins, J.R.6
-
13
-
-
13944252067
-
The life cycle of C-myc: From synthesis to degradation
-
15467447
-
Sears RC. The life cycle of C-myc: from synthesis to degradation. Cell cycle 2004; 3:1133-1137; PMID:15467447; http://dx.doi.org/10.4161/cc.3.9.1145
-
(2004)
Cell Cycle
, vol.3
, pp. 1133-1137
-
-
Sears, R.C.1
-
15
-
-
84936857771
-
Myc and its interactors take shape
-
24933113
-
Tu WB, Helander S, Pilstal R, Hickman KA, Lourenco C, Jurisica I, Raught B, Wallner B, Sunnerhagen M, Penn LZ. Myc and its interactors take shape. Biochim Biophys Acta 2015; 1849:469-483; PMID:24933113; http://dx.doi.org/10.1016/j.bbagrm.2014.06.002
-
(2015)
Biochim Biophys Acta
, vol.1849
, pp. 469-483
-
-
Tu, W.B.1
Helander, S.2
Pilstal, R.3
Hickman, K.A.4
Lourenco, C.5
Jurisica, I.6
Raught, B.7
Wallner, B.8
Sunnerhagen, M.9
Penn, L.Z.10
-
16
-
-
0026025416
-
Degradation of nuclear oncoproteins by the ubiquitin system in vitro
-
1846034
-
Ciechanover A, DiGiuseppe JA, Bercovich B, Orian A, Richter JD, Schwartz AL, Brodeur GM. Degradation of nuclear oncoproteins by the ubiquitin system in vitro. Proc Natl Acad Sci U S A 1991; 88:139-143; PMID:1846034
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 139-143
-
-
Ciechanover, A.1
Digiuseppe, J.A.2
Bercovich, B.3
Orian, A.4
Richter, J.D.5
Schwartz, A.L.6
Brodeur, G.M.7
-
17
-
-
3543060464
-
Myc boxes, which are conserved in myc family proteins, are signals for protein degradation via the proteasome
-
9742113
-
Flinn EM, Busch CM, Wright AP. myc boxes, which are conserved in myc family proteins, are signals for protein degradation via the proteasome. Mol Cell Biol 1998; 18:5961-5969; PMID:9742113
-
(1998)
Mol Cell Biol
, vol.18
, pp. 5961-5969
-
-
Flinn, E.M.1
Busch, C.M.2
Wright, A.P.3
-
18
-
-
0028023421
-
Hierarchical phosphorylation at N-terminal transformation-sensitive sites in c-Myc protein is regulated by mitogens and in mitosis
-
8035827
-
Lutterbach B, Hann SR. Hierarchical phosphorylation at N-terminal transformation-sensitive sites in c-Myc protein is regulated by mitogens and in mitosis. Mol Cell Biol 1994; 14:5510-5522; PMID:8035827; http://dx.doi.org/10.1128/MCB.14.8.5510
-
(1994)
Mol Cell Biol
, vol.14
, pp. 5510-5522
-
-
Lutterbach, B.1
Hann, S.R.2
-
19
-
-
0347695988
-
Phosphorylation by gly-cogen synthase kinase-3 controls c-myc proteolysis and subnuclear localization
-
14563837
-
Gregory MA, Qi Y, Hann SR. Phosphorylation by gly-cogen synthase kinase-3 controls c-myc proteolysis and subnuclear localization. J Biol Chem 2003; 278:51606-51612; PMID:14563837; http://dx.doi.org/10.1074/jbc.M310722200
-
(2003)
J Biol Chem
, vol.278
, pp. 51606-51612
-
-
Gregory, M.A.1
Qi, Y.2
Hann, S.R.3
-
20
-
-
0034037132
-
The c-Myc transactivation domain is a direct modulator of apoptotic versus proliferative signals
-
10825194
-
Chang DW, Claassen GF, Hann SR, Cole MD. The c-Myc transactivation domain is a direct modulator of apoptotic versus proliferative signals. Mol Cell Biol 2000; 20:4309-4319; PMID:10825194; http://dx.doi.org/10.1128/MCB.20.12.4309-4319.2000
-
(2000)
Mol Cell Biol
, vol.20
, pp. 4309-4319
-
-
Chang, D.W.1
Claassen, G.F.2
Hann, S.R.3
Cole, M.D.4
-
21
-
-
0028023421
-
Hierarchical phosphorylation at N-terminal transformation-sensitive sites in c-Myc protein is regulated by mitogens and in mitosis
-
8035827
-
Lutterbach B, aHann SR. Hierarchical phosphorylation at N-terminal transformation-sensitive sites in c-Myc protein is regulated by mitogens and in mitosis. Mol Cell Biol 1994; 14:5510-5522; PMID:8035827; http://dx.doi.org/10.1128/MCB.14.8.5510
-
(1994)
Mol Cell Biol
, vol.14
, pp. 5510-5522
-
-
Lutterbach, B.1
Ahann, S.R.2
-
22
-
-
0036192061
-
The myc onco-gene: MarvelouslY Complex
-
11885563
-
Oster SK, Ho CS, Soucie EL, Penn LZ. The myc onco-gene: MarvelouslY Complex. Adv Cancer Res 2002; 84:81-154; PMID:11885563; http://dx.doi.org/10.1016/S0065-230X(02)84004-0
-
(2002)
Adv Cancer Res
, vol.84
, pp. 81-154
-
-
Oster, S.K.1
Ho, C.S.2
Soucie, E.L.3
Penn, L.Z.4
-
23
-
-
2342526543
-
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells
-
15048125
-
Yeh E, Cunningham M, Arnold H, Chasse D, Mon-teith T, Ivaldi G, Hahn WC, Stukenberg PT, Shenoli-kar S, Uchida T, et al. A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells. Nat Cell Biol 2004; 6:308-318; PMID:15048125; http://dx.doi.org/10.1038/ncb1110
-
(2004)
Nat Cell Biol
, vol.6
, pp. 308-318
-
-
Yeh, E.1
Cunningham, M.2
Arnold, H.3
Chasse, D.4
Mon-Teith, T.5
Ivaldi, G.6
Hahn, W.C.7
Stukenberg, P.T.8
Shenoli-Kar, S.9
Uchida, T.10
-
24
-
-
2642549141
-
The Drosophila F box protein archipelago regulates dMyc protein levels in vivo
-
15182669
-
Moberg KH, Mukherjee A, Veraksa A, Artavanis-Tsa-konas S, Hariharan IK. The Drosophila F box protein archipelago regulates dMyc protein levels in vivo. Curr Biol 2004; 14:965-974; PMID:15182669; http://dx.doi.org/10.1016/j.cub.2004.04.040
-
(2004)
Curr Biol
, vol.14
, pp. 965-974
-
-
Moberg, K.H.1
Mukherjee, A.2
Veraksa, A.3
Artavanis-Tsa-Konas, S.4
Hariharan, I.K.5
-
25
-
-
2942614705
-
Phosphorylation-depen-dent degradation of c-Myc is mediated by the F-box protein Fbw7
-
15103331
-
Yada M, Hatakeyama S, Kamura T, Nishiyama M, Tsunematsu R, Imaki H, Ishida N, Okumura F, Nakayama K, Nakayama KI. Phosphorylation-depen-dent degradation of c-Myc is mediated by the F-box protein Fbw7. EMBO J 2004; 23:2116-2125; PMID:15103331; http://dx.doi.org/10.1038/sj.emboj.7600217
-
(2004)
EMBO J
, vol.23
, pp. 2116-2125
-
-
Yada, M.1
Hatakeyama, S.2
Kamura, T.3
Nishiyama, M.4
Tsunematsu, R.5
Imaki, H.6
Ishida, N.7
Okumura, F.8
Nakayama, K.9
Nakayama, K.I.10
-
26
-
-
2942650133
-
The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation
-
15150404
-
Welcker M, Orian A, Jin J, Grim JE, Harper JW, Eisenman RN, Clurman B E. The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation. Proc Natl Acad Sci U S A 2004; 101:9085-9090; PMID:15150404; http://dx.doi.org/10.1073/pnas.0402770101
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 9085-9090
-
-
Welcker, M.1
Orian, A.2
Jin, J.3
Grim, J.E.4
Harper, J.W.5
Eisenman, R.N.6
Clurman, B.E.7
-
27
-
-
6944227551
-
A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size
-
15498494
-
Welcker M, Orian A, Grim JE, Eisenman RN, Clur-man BE. A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size. Curr Biol 2004; 14:965-974; PMID:15498494; http://dx.doi.org/10.1016/j.cub.2004.09.083
-
(2004)
Curr Biol
, vol.14
, pp. 965-974
-
-
Welcker, M.1
Orian, A.2
Grim, J.E.3
Eisenman, R.N.4
Clur-Man, B.E.5
-
28
-
-
0034653998
-
Larsson LG. C-Myc hot spot mutations in lymphomas result in inefficient ubiquitination and decreased proteasome-mediated turnover
-
10706881
-
Bahram F, von der Lehr N, Cetinkaya C, Larsson LG. c-Myc hot spot mutations in lymphomas result in inefficient ubiquitination and decreased proteasome-mediated turnover. Blood 2000; 95:2104-2110; PMID:10706881
-
(2000)
Blood
, vol.95
, pp. 2104-2110
-
-
Bahram, F.1
Von Der Lehr, N.2
Cetinkaya, C.3
-
29
-
-
0034059667
-
C-Myc proteolysis by the ubiq-uitin-proteasome pathway: Stabilization of c-Myc in Burkitt's lymphoma cells
-
10713166
-
Gregory MA, Hann SR. c-Myc proteolysis by the ubiq-uitin-proteasome pathway: stabilization of c-Myc in Burkitt's lymphoma cells. Mol Cell Biol. 2000; 20:2423-2435; PMID:10713166; http://dx.doi.org/10.1128/MCB.20.7.2423-2435.2000
-
(2000)
Mol Cell Biol
, vol.20
, pp. 2423-2435
-
-
Gregory, M.A.1
Hann, S.R.2
-
30
-
-
0033081027
-
Destruction ofMyc by ubiquitin-mediated proteolysis: Cancer-associated and transforming mutations stabilize Myc
-
9927431
-
Salghetti SE, Kim SY, Tansey WP. Destruction ofMyc by ubiquitin-mediated proteolysis: cancer-associated and transforming mutations stabilize Myc. EMBO J 1999; 18, 717-726; PMID:9927431
-
(1999)
EMBO J
, vol.18
, pp. 717-726
-
-
Salghetti, S.E.1
Kim, S.Y.2
Tansey, W.P.3
-
31
-
-
23844469503
-
Evasion ofthe p53 tumour surveillance network by tumour-derived MYC mutants
-
16094360
-
Hemann MT, Bric A, Teruya-Feldstein J, Herbst A, Nilsson JA, Cordon-Cardo C, Cleveland JL, Tansey WP, Lowe SW. Evasion ofthe p53 tumour surveillance network by tumour-derived MYC mutants. Nature 2005; 436:807-811; PMID:16094360; http://dx.doi.org/10.1038/nature03845
-
(2005)
Nature
, vol.436
, pp. 807-811
-
-
Hemann, M.T.1
Bric, A.2
Teruya-Feldstein, J.3
Herbst, A.4
Nilsson, J.A.5
Cordon-Cardo, C.6
Cleveland, J.L.7
Tansey, W.P.8
Lowe, S.W.9
-
32
-
-
79551552058
-
Phosphorylation regulates c-Myc's oncogenic activity in the mammary gland
-
21266350
-
Wang X, Cunningham M, Zhang X, Tokarz S, Laraway B, Troxell M, Sears RC. Phosphorylation regulates c-Myc's oncogenic activity in the mammary gland. Cancer Res 2011; 71:925-936; PMID:21266350; http://dx.doi.org/10.1158/0008-5472.CAN-10-1032
-
(2011)
Cancer Res
, vol.71
, pp. 925-936
-
-
Wang, X.1
Cunningham, M.2
Zhang, X.3
Tokarz, S.4
Laraway, B.5
Troxell, M.6
Sears, R.C.7
-
33
-
-
38549086019
-
FBW7 ubiquitin ligase: A tumour suppressor at the crossroads of cell division, growth and differentiation
-
18094723
-
Welcker M, Clurman BE. FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation. Nat Rev Cancer 2008; 8:83-93; PMID:18094723; http://dx.doi.org/10.1038/nrc2290
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 83-93
-
-
Welcker, M.1
Clurman, B.E.2
-
34
-
-
12444264823
-
The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription
-
12769844
-
von der Lehr N, Johansson S, Wu S, Bahram F, Castell A, Cetinkaya C, Hydbring P, Weidung I, Nakayama K, Nakayama KI, et al. The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription. Mol Cell 2003; 11:1189-1200; PMID:12769844; http://dx.doi.org/10.1016/S1097-2765(03)00193-X
-
(2003)
Mol Cell
, vol.11
, pp. 1189-1200
-
-
Von Der Lehr, N.1
Johansson, S.2
Wu, S.3
Bahram, F.4
Castell, A.5
Cetinkaya, C.6
Hydbring, P.7
Weidung, I.8
Nakayama, K.9
Nakayama, K.I.10
-
35
-
-
2342513572
-
Implication of the ubiquitin/proteasome system in Myc-regulated transcription
-
12963825
-
von der Lehr N, Johansson S, Larsson LG. Implication of the ubiquitin/proteasome system in Myc-regulated transcription. Cell Cycle 2003; 2:403-407; PMID:12963825; http://dx.doi.org/10.4161/cc.2.5.484
-
(2003)
Cell Cycle
, vol.2
, pp. 403-407
-
-
Von Der Lehr, N.1
Johansson, S.2
Larsson, L.G.3
-
36
-
-
0037648338
-
Skp2 regulates Myc protein stability and activity
-
12769843
-
Kim SY, Herbst A, Tworkowski KA, Salghetti SE, Tan-sey WP. Skp2 regulates Myc protein stability and activity. Mol Cell 2003; 11:1177-1188; PMID:12769843; http://dx.doi.org/10.1016/S1097-2765(03)00173-4
-
(2003)
Mol Cell
, vol.11
, pp. 1177-1188
-
-
Kim, S.Y.1
Herbst, A.2
Tworkowski, K.A.3
Salghetti, S.E.4
Tan-Sey, W.P.5
-
37
-
-
84872548776
-
Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activity
-
23277542
-
Zhang Q, Spears E, Boone DN, Li Z, Gregory MA, Hann SR. Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activity. Proc Natl Acad Sci U S A 2013; 110:978-983; PMID:23277542; http://dx.doi.org/10.1073/pnas.1208334110
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 978-983
-
-
Zhang, Q.1
Spears, E.2
Boone, D.N.3
Li, Z.4
Gregory, M.A.5
Hann, S.R.6
-
38
-
-
84880651314
-
Pin1 regulates the dynamics of c-Myc DNA binding to facilitate target gene regulation and oncogenesis
-
23716601
-
Farrell AS, Pelz C, Wang X, Daniel CJ, Wang Z, Su Y, Janghorban M, Zhang X, Morgan C, Impey S, et al. Pin1 regulates the dynamics of c-Myc DNA binding to facilitate target gene regulation and oncogenesis. Mol Cell Biol 2013; 33:2930-2949; PMID:23716601; http://dx.doi.org/10.1128/MCB.01455-12
-
(2013)
Mol Cell Biol
, vol.33
, pp. 2930-2949
-
-
Farrell, A.S.1
Pelz, C.2
Wang, X.3
Daniel, C.J.4
Wang, Z.5
Su, Y.6
Janghorban, M.7
Zhang, X.8
Morgan, C.9
Impey, S.10
-
39
-
-
77951978532
-
Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis
-
20383141
-
Chan CH, Lee SW, Li CF, Wang J, Yang WL, Wu CY, Wu J, Nakayama KI, Kang HY, Huang HY, et al. Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis. Nat Cell Biol 2010;12:457-467; PMID:20383141; http://dx.doi.org/10.1038/ncb2047
-
(2010)
Nat Cell Biol
, vol.12
, pp. 457-467
-
-
Chan, C.H.1
Lee, S.W.2
Li, C.F.3
Wang, J.4
Yang, W.L.5
Wu, C.Y.6
Wu, J.7
Nakayama, K.I.8
Kang, H.Y.9
Huang, H.Y.10
-
40
-
-
84888251433
-
ERK-dependent downregulation of Skp2 reduces Myc activity with HGF, leading to inhibition of cell proliferation through a decrease in Id1 expression
-
24177224
-
Li X, Bian Y, Takizawa Y, Hashimoto T, Ikoma T, Tanaka J, Kitamura N, Inagaki Y, Komada M, Tanaka T. ERK-dependent downregulation of Skp2 reduces Myc activity with HGF, leading to inhibition of cell proliferation through a decrease in Id1 expression. Mol Cancer Res 2013; 11:1437-1447; PMID:24177224; http://dx.doi.org/10.1158/1541-7786.MCR-12-0718
-
(2013)
Mol Cancer Res
, vol.11
, pp. 1437-1447
-
-
Li, X.1
Bian, Y.2
Takizawa, Y.3
Hashimoto, T.4
Ikoma, T.5
Tanaka, J.6
Kitamura, N.7
Inagaki, Y.8
Komada, M.9
Tanaka, T.10
-
41
-
-
27544473311
-
The ubiquitin ligase HectH9 regulates transcrip-tional activation by Myc and is essential for tumor cell proliferation
-
16269333
-
Adhikary S, Marinoni F, Hock A, Hulleman E, Popov N, Beier R, Bernard S, Quarto M, Capra M, Goettig S, et al. The ubiquitin ligase HectH9 regulates transcrip-tional activation by Myc and is essential for tumor cell proliferation. Cell 2005; 123:409-421; PMID:16269333; http://dx.doi.org/10.1016/j.cell.2005.08.016
-
(2005)
Cell
, vol.123
, pp. 409-421
-
-
Adhikary, S.1
Marinoni, F.2
Hock, A.3
Hulleman, E.4
Popov, N.5
Beier, R.6
Bernard, S.7
Quarto, M.8
Capra, M.9
Goettig, S.10
-
42
-
-
84918519265
-
Tumor cell-specific inhibition of MYC function using small molecule inhibitors ofthe HUWE1 ubiquitin ligase
-
25253726
-
Peter S, Bultinck J, Myant K, Jaenicke LA, Walz S, Muller J, Gmachl M, Treu M, Boehmelt G, Ade CP, et al. Tumor cell-specific inhibition of MYC function using small molecule inhibitors ofthe HUWE1 ubiquitin ligase. EMBO Mol Med 2014; 6:1525-1541; PMID:25253726; http://dx.doi.org/10.15252/emmm.201403927
-
(2014)
EMBO Mol Med
, vol.6
, pp. 1525-1541
-
-
Peter, S.1
Bultinck, J.2
Myant, K.3
Jaenicke, L.A.4
Walz, S.5
Muller, J.6
Gmachl, M.7
Treu, M.8
Boehmelt, G.9
Ade, C.P.10
-
43
-
-
84880026012
-
CDK-mediated activation of the SCF(FBXO) (28) ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer
-
23776131
-
Cepeda D, Ng HF, Sharifi HR Mahmoudi S, Cerrato VS, Fredlund E, Magnusson K, Nilsson H, Malyukova A, Rantala J, et al. CDK-mediated activation of the SCF(FBXO) (28) ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer. EMBO Mol Med 2013; 5:999-1018; PMID:23776131; http://dx.doi.org/10.1002/emmm.201202341
-
(2013)
EMBO Mol Med
, vol.5
, pp. 999-1018
-
-
Cepeda, D.1
Ng, H.F.2
Sharifi Hr Mahmoudi, S.3
Cerrato, V.S.4
Fredlund, E.5
Magnusson, K.6
Nilsson, H.7
Malyukova, A.8
Rantala, J.9
-
44
-
-
77957564565
-
Ubiquity-lation of the amino terminus of Myc by SCF(Fl-TrCP) antagonizes SCF(Fbw7)-mediated turnover
-
20852628
-
Popov N, Schulein C, Jaenicke LA, Eilers M. Ubiquity-lation of the amino terminus of Myc by SCF(fl-TrCP) antagonizes SCF(Fbw7)-mediated turnover. Nat Cell Biol 2010; 12:973-981; PMID:20852628; http://dx.doi.org/10.1038/ncb2104
-
(2010)
Nat Cell Biol
, vol.12
, pp. 973-981
-
-
Popov, N.1
Schulein, C.2
Jaenicke, L.A.3
Eilers, M.4
-
45
-
-
84928042155
-
Bae I. B-TrCP1 degradation is a novel action mechanism of PI3K/mTOR inhibitors in triple-negative breast cancer cells
-
25721419
-
Yi YW, Kang HJ, Bae EJ, Oh S, Seong YS, Bae I. b-TrCP1 degradation is a novel action mechanism of PI3K/mTOR inhibitors in triple-negative breast cancer cells. Exp Mol Med 2015; 47, e143; PMID:25721419; http://dx.doi.org/10.1038/emm.2014.127
-
(2015)
Exp Mol Med
, vol.47
-
-
Yi, Y.W.1
Kang, H.J.2
Bae, E.J.3
Oh, S.4
Seong, Y.S.5
-
46
-
-
77953934816
-
Myc protein is stabilized by suppression of a novel E3 ligase complex in cancer cells
-
20551172
-
Choi SH, Wright JB, Gerber SA, Cole MD. Myc protein is stabilized by suppression of a novel E3 ligase complex in cancer cells. Genes Dev 2010; 24:1236-1241; PMID:20551172; http://dx.doi.org/10.1101/gad.1920310
-
(2010)
Genes Dev
, vol.24
, pp. 1236-1241
-
-
Choi, S.H.1
Wright, J.B.2
Gerber, S.A.3
Cole, M.D.4
-
47
-
-
84943787999
-
The G1 phase E3 ubiquitin ligase TRUSS that gets deregulated in human cancers is a novel substrate of the S-phase E3 ubiquitin ligase Skp2
-
26038816
-
Jamal A, Swarnalatha M, Sultana S, Joshi P, Panda SK, Kumar V. The G1 phase E3 ubiquitin ligase TRUSS that gets deregulated in human cancers is a novel substrate of the S-phase E3 ubiquitin ligase Skp2. Cell Cycle, 2015; 14:2688-2700; PMID:26038816; http://dx.doi.org/10.1080/15384101.2015.1056946
-
(2015)
Cell Cycle
, vol.14
, pp. 2688-2700
-
-
Jamal, A.1
Swarnalatha, M.2
Sultana, S.3
Joshi, P.4
Panda, S.K.5
Kumar, V.6
-
48
-
-
61349191567
-
The TRIM-NHL protein TRIM32 activates micro RNAs and prevents self-renewal in mouse neural progenitors
-
19269368
-
Schwamborn JC, Berezikov E, Knoblich JA. The TRIM-NHL protein TRIM32 activates micro RNAs and prevents self-renewal in mouse neural progenitors. Cell 2009; 136:913-925; PMID:19269368; http://dx.doi.org/10.1016/j.cell.2008.12.024
-
(2009)
Cell
, vol.136
, pp. 913-925
-
-
Schwamborn, J.C.1
Berezikov, E.2
Knoblich, J.A.3
-
49
-
-
81755160906
-
Role ofPirh2 in mediating the regulation of p53 and c-Myc
-
22125490
-
Hakem A, Bohgaki M, Lemmers B, Tai E, Salmena L, Matysiak-Zablocki E, Jung YS, Karaskova J, Kaustov L, Duan S, et al. Role ofPirh2 in mediating the regulation of p53 and c-Myc. PLoS genetics 2011; 7:e1002360; PMID:22125490; http://dx.doi.org/10.1371/journal.pgen.1002360
-
(2011)
Plos Genetics
, vol.7
-
-
Hakem, A.1
Bohgaki, M.2
Lemmers, B.3
Tai, E.4
Salmena, L.5
Matysiak-Zablocki, E.6
Jung, Y.S.7
Karaskova, J.8
Kaustov, L.9
Duan, S.10
-
50
-
-
0033013126
-
Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions
-
10330192
-
Ballinger CA, Connell P, Wu Y, Hu Z, Thompson LJ, Yin LY, Patterson C. Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions. Mol Cell Biol 1999; 19:4535-4545; PMID:10330192
-
(1999)
Mol Cell Biol
, vol.19
, pp. 4535-4545
-
-
Ballinger, C.A.1
Connell, P.2
Wu, Y.3
Hu, Z.4
Thompson, L.J.5
Yin, L.Y.6
Patterson, C.7
-
51
-
-
84874785567
-
The ubiquitin ligase CHIP regulates c-Myc stability and transcriptional activity
-
22543587
-
Paul I, Ahmed SF, Bhowmik A, Deb S, Ghosh MK. The ubiquitin ligase CHIP regulates c-Myc stability and transcriptional activity. Oncogene 2013; 32:1284-1295; PMID:22543587; http://dx.doi.org/10.1038/onc.2012.144
-
(2013)
Oncogene
, vol.32
, pp. 1284-1295
-
-
Paul, I.1
Ahmed, S.F.2
Bhowmik, A.3
Deb, S.4
Ghosh, M.K.5
-
52
-
-
84941343714
-
FBXO32 Targets c-Myc for Proteasomal Degradation and Inhibits c-Myc Activity
-
25944903
-
Mei Z, Zhang D, Hu B, Wang J, Shen X, a Xiao W. FBXO32 Targets c-Myc for Proteasomal Degradation and Inhibits c-Myc Activity. J Biol Chem 2015; 290:16202-16214; PMID:25944903; http://dx.doi.org/10.1074/jbc.M115.645978
-
(2015)
J Biol Chem
, vol.290
, pp. 16202-16214
-
-
Mei, Z.1
Zhang, D.2
Hu, B.3
Wang, J.4
Shen, X.5
A Xiao, W.6
-
53
-
-
68049084674
-
Breaking the chains: Structure and function of the deubiquitinases
-
19626045
-
Komander D, Clague MJ, Urbe S. Breaking the chains: structure and function of the deubiquitinases. Nat Rev Mol Cell Biol 2009; 10:550-563; PMID:19626045; http://dx.doi.org/10.1038/nrm2731
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 550-563
-
-
Komander, D.1
Clague, M.J.2
Urbe, S.3
-
54
-
-
28344456279
-
A genomic and functional inventory of deubiquitinating enzymes
-
16325574
-
Nijman SM, Luna-Vargas MP, Velds A, Brummelkamp TR, Dirac AM, Sixma TK, Bernards R. A genomic and functional inventory of deubiquitinating enzymes. Cell 2005; 123:773-786; PMID:16325574; http://dx.doi.org/10.1016/j.cell.2005.11.007
-
(2005)
Cell
, vol.123
, pp. 773-786
-
-
Nijman, S.M.1
Luna-Vargas, M.P.2
Velds, A.3
Brummelkamp, T.R.4
Dirac, A.M.5
Sixma, T.K.6
Bernards, R.7
-
55
-
-
34347401998
-
The ubiquitin-specific protease USP28 is required for MYC stability
-
17558397
-
Popov N, Wanzel M, Madiredjo M, Zhang D, Beijers-bergen R, Bernards R, Moll R, Elledge SJ, Eilers M. The ubiquitin-specific protease USP28 is required for MYC stability. Nat Cell Biol 2007; 9:765-774; PMID:17558397; http://dx.doi.org/10.1038/ncb1601
-
(2007)
Nat Cell Biol
, vol.9
, pp. 765-774
-
-
Popov, N.1
Wanzel, M.2
Madiredjo, M.3
Zhang, D.4
Beijers-Bergen, R.5
Bernards, R.6
Moll, R.7
Elledge, S.J.8
Eilers, M.9
-
56
-
-
35848942129
-
Fbw7 and Usp28 regulate myc protein stability in response to DNA damage
-
17873522
-
Popov N, Herold S, Llamazares M, Schulein C, Eilers M. Fbw7 and Usp28 regulate myc protein stability in response to DNA damage. Cell cycle 2007; 6:2327-2331; PMID:17873522; http://dx.doi.org/10.1016/j.celrep.2014.09.057
-
(2007)
Cell Cycle
, vol.6
, pp. 2327-2331
-
-
Popov, N.1
Herold, S.2
Llamazares, M.3
Schulein, C.4
Eilers, M.5
-
57
-
-
84919710063
-
Dual regulation of Fbw7 function and oncogenic transformation by Usp28
-
25437563
-
Schulein-Volk C, Wolf E, Zhu J, Xu W, Taranets L, Hellmann A, Janicke LA, Diefenbacher ME, Behrens A, Eilers M, et al. Dual regulation of Fbw7 function and oncogenic transformation by Usp28. Cell Rep 2014; 9:1099-1109; PMID:25437563; http://dx.doi.org/10.1016/j.celrep.2014.09.057
-
(2014)
Cell Rep
, vol.9
, pp. 1099-1109
-
-
Schulein-Volk, C.1
Wolf, E.2
Zhu, J.3
Xu, W.4
Taranets, L.5
Hellmann, A.6
Janicke, L.A.7
Diefenbacher, M.E.8
Behrens, A.9
Eilers, M.10
-
58
-
-
84928934406
-
Usp28 counteracts Fbw7 in intestinal homeostasis and cancer
-
25716680
-
Diefenbacher ME, Chakraborty A, Blake SM, Mitter R, Popov N, Eilers M, Behrens A. Usp28 counteracts Fbw7 in intestinal homeostasis and cancer. Cancer Res 2015; 75:1181-1186; PMID:25716680; http://dx.doi.org/10.1158/0008-5472.CAN-14-1726
-
(2015)
Cancer Res
, vol.75
, pp. 1181-1186
-
-
Diefenbacher, M.E.1
Chakraborty, A.2
Blake, S.M.3
Mitter, R.4
Popov, N.5
Eilers, M.6
Behrens, A.7
-
59
-
-
84937966446
-
USP37 directly deubiqui-tinates and stabilizes c-Myc in lung cancer
-
25284584
-
Pan J, Deng Q, Jiang C, Wang X, Niu T, Li H, Chen T, Jin J, Pan W, Cai X, et al. USP37 directly deubiqui-tinates and stabilizes c-Myc in lung cancer. Oncogene 2015; 34:3957-3967; PMID:25284584; http://dx.doi.org/10.1038/onc.2014.327
-
(2015)
Oncogene
, vol.34
, pp. 3957-3967
-
-
Pan, J.1
Deng, Q.2
Jiang, C.3
Wang, X.4
Niu, T.5
Li, H.6
Chen, T.7
Jin, J.8
Pan, W.9
Cai, X.10
-
60
-
-
20044375377
-
C-Myc associates with ribosomal DNA and activates RNA polymerase I transcription
-
15723053
-
Arabi A, Wu S, Ridderstrale K, Bierhoff H, Shiue C, Fatyol K, Fahlen S, Hydbring P, Soderberg O, Grummt I, et al. c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription. Nat Cell Biol 2005; 7:303-310; PMID:15723053; http://dx.doi.org/10.1038/ncb1225
-
(2005)
Nat Cell Biol
, vol.7
, pp. 303-310
-
-
Arabi, A.1
Wu, S.2
Ridderstrale, K.3
Bierhoff, H.4
Shiue, C.5
Fatyol, K.6
Fahlen, S.7
Hydbring, P.8
Soderberg, O.9
Grummt, I.10
-
61
-
-
14744284578
-
C-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I
-
15723054
-
Grandori C, Gomez-Roman N, Felton-Edkins ZA, Ngouenet C, Galloway DA, Eisenman RN, White RJ. c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I. Nat Cell Biol 2005; 7:311-318; PMID:15723054; http://dx.doi.org/10.1038/ncb1224
-
(2005)
Nat Cell Biol
, vol.7
, pp. 311-318
-
-
Grandori, C.1
Gomez-Roman, N.2
Felton-Edkins, Z.A.3
Ngouenet, C.4
Galloway, D.A.5
Eisenman, R.N.6
White, R.J.7
-
62
-
-
54849406775
-
Crosstalk between c-Myc and ribosome in ribosomal biogenesis and cancer
-
18773413
-
Dai MS, Lu H. Crosstalk between c-Myc and ribosome in ribosomal biogenesis and cancer. J Cell Biochem 2008; 105:670-677; PMID:18773413; http://dx.doi.org/10.1002/jcb.21895
-
(2008)
J Cell Biochem
, vol.105
, pp. 670-677
-
-
Dai, M.S.1
Lu, H.2
-
63
-
-
77949920493
-
MYC as a regulator of ribosome biogenesis and protein synthesis
-
20332779
-
van Riggelen J, Yetil A, Felsher DW. MYC as a regulator of ribosome biogenesis and protein synthesis. Nat Rev Cancer 2010; 10:301-309; PMID:20332779; http://dx.doi.org/10.1038/nrc2819
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 301-309
-
-
Van Riggelen, J.1
Yetil, A.2
Felsher, D.W.3
-
64
-
-
84925424005
-
The nucleolar ubiquitin-specific protease USP36 deubi-quitinates and stabilizes c-Myc
-
25775507
-
Sun XX, He X, Yin L, Komada M, Sears RC, Dai MS. The nucleolar ubiquitin-specific protease USP36 deubi-quitinates and stabilizes c-Myc. Proc Natl Acad Sci U S A 2015; 112:3734-3739; PMID:25775507; http://dx.doi.org/10.1073/pnas.1411713112
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. 3734-3739
-
-
Sun, X.X.1
He, X.2
Yin, L.3
Komada, M.4
Sears, R.C.5
Dai, M.S.6
-
65
-
-
45849134528
-
Differential display identifies overex-pression of the USP36 gene, encoding a deubiquitinat-ing enzyme, in ovarian cancer
-
18566677
-
Li J, Olson LM, Zhang Z, Li L, Bidder M, Nguyen L, Pfeifer J, Rader JS. Differential display identifies overex-pression of the USP36 gene, encoding a deubiquitinat-ing enzyme, in ovarian cancer. Int J Med Sci 2008; 5:133-142; PMID:18566677; http://dx.doi.org/10.7150/ijms.5.133
-
(2008)
Int J Med Sci
, vol.5
, pp. 133-142
-
-
Li, J.1
Olson, L.M.2
Zhang, Z.3
Li, L.4
Bidder, M.5
Nguyen, L.6
Pfeifer, J.7
Rader, J.S.8
-
66
-
-
70350463844
-
Nucleophosmin/ B23 regulates ubiquitin dynamics in nucleoli by recruiting deubiquitylating enzyme USP36
-
19679658
-
Endo A, Kitamura N, Komada M. Nucleophosmin/ B23 regulates ubiquitin dynamics in nucleoli by recruiting deubiquitylating enzyme USP36. J Biol Chem 2009; 284:27918-27923; PMID:19679658; http://dx.doi.org/10.1074/jbc.M109.037218
-
(2009)
J Biol Chem
, vol.284
, pp. 27918-27923
-
-
Endo, A.1
Kitamura, N.2
Komada, M.3
-
67
-
-
66149152311
-
Nucleolar structure and function are regulated by the deubiquitylating enzyme USP36
-
19208757
-
Endo A, Matsumoto M, Inada T, Yamamoto A, Nakayama KI, Kitamura N, Komada M. Nucleolar structure and function are regulated by the deubiquitylating enzyme USP36. J Cell Sci 2009; 122:678-686; PMID:19208757; http://dx.doi.org/10.1242/jcs.044461
-
(2009)
J Cell Sci
, vol.122
, pp. 678-686
-
-
Endo, A.1
Matsumoto, M.2
Inada, T.3
Yamamoto, A.4
Nakayama, K.I.5
Kitamura, N.6
Komada, M.7
-
68
-
-
84865758440
-
A conserved deubiquitinating enzyme controls cell growth by regulating RNA polymerase I stability
-
22902402
-
Richardson LA, Reed BJ, Charette JM, Freed EF, Fre-drickson EK, Locke MN, Baserga SJ, Gardner RG. A conserved deubiquitinating enzyme controls cell growth by regulating RNA polymerase I stability. Cell Rep 2012; 2:372-385; PMID:22902402; http://dx.doi.org/10.1016/j.celrep.2012.07.009
-
(2012)
Cell Rep
, vol.2
, pp. 372-385
-
-
Richardson, L.A.1
Reed, B.J.2
Charette, J.M.3
Freed, E.F.4
Fre-Drickson, E.K.5
Locke, M.N.6
Baserga, S.J.7
Gardner, R.G.8
-
69
-
-
84862623665
-
The deubiqui-tinating enzyme USP36 controls selective autophagy activation by ubiquitinated proteins
-
22622177
-
Taillebourg E, Gregoire I, Viargues P, Jacomin AC, Thevenon D, Faure M, Fauvarque MO. The deubiqui-tinating enzyme USP36 controls selective autophagy activation by ubiquitinated proteins. Autophagy 2012; 8:767-779; PMID:22622177; http://dx.doi.org/10.4161/auto.19381
-
(2012)
Autophagy
, vol.8
, pp. 767-779
-
-
Taillebourg, E.1
Gregoire, I.2
Viargues, P.3
Jacomin, A.C.4
Thevenon, D.5
Faure, M.6
Fauvarque, M.O.7
-
70
-
-
72649083654
-
The Drosophila ubiquitin-specific protease dUSP36/Scny targets IMD to prevent constitutive immune signaling
-
19837371
-
Thevenon D, Engel E, Avet-Rochex A, Gottar M, Ber-geret E, Tricoire H, Benaud C, Baudier J, Taillebourg E, Fauvarque MO. The Drosophila ubiquitin-specific protease dUSP36/Scny targets IMD to prevent constitutive immune signaling. Cell Host Microbe 2009; 6:309-320; PMID:19837371; http://dx.doi.org/10.1016/j.chom.2009.09.007
-
(2009)
Cell Host Microbe
, vol.6
, pp. 309-320
-
-
Thevenon, D.1
Engel, E.2
Avet-Rochex, A.3
Gottar, M.4
Ber-Geret, E.5
Tricoire, H.6
Benaud, C.7
Baudier, J.8
Taillebourg, E.9
Fauvarque, M.O.10
-
71
-
-
34347388162
-
MYC degradation: Deubiquitinating enzymes enter the dance
-
17603505
-
Amati B, Sanchez-Arevalo Lobo VJ. MYC degradation: deubiquitinating enzymes enter the dance. Nat Cell Biol 2007; 9:729-731; PMID:17603505; http://dx.doi.org/10.1038/ncb0707-729
-
(2007)
Nat Cell Biol
, vol.9
, pp. 729-731
-
-
Amati, B.1
Sanchez-Arevalo Lobo, V.J.2
|