메뉴 건너뛰기




Volumn 6, Issue , 2016, Pages

Utilizing yeast chemogenomic profiles for the prediction of pharmacogenomic associations in humans

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MODEL; DRUG EFFECTS; FUNGAL GENOME; GENETICS; HUMAN; PHARMACOGENETICS; PRECLINICAL STUDY; PROCEDURES; SACCHAROMYCES CEREVISIAE;

EID: 84964000486     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep23703     Document Type: Article
Times cited : (4)

References (46)
  • 1
    • 0035575568 scopus 로고    scopus 로고
    • Personalized medicine: Revolutionizing drug discovery and patient care
    • Ginsburg, G. S., McCarthy, J. J. Personalized medicine: revolutionizing drug discovery and patient care. Trends Biotechnol. 19, 491-496 (2001).
    • (2001) Trends Biotechnol. , vol.19 , pp. 491-496
    • Ginsburg, G.S.1    McCarthy, J.J.2
  • 2
    • 84893108288 scopus 로고    scopus 로고
    • Promise of pharmacogenomics for drug discovery treatment and prevention of Parkinson's Disease. A perspective
    • Payami, H., Factor, S. A. Promise of Pharmacogenomics for Drug Discovery, Treatment and Prevention of Parkinson's Disease. A Perspective. Neurotherapeutics 11, 111-116 (2014).
    • (2014) Neurotherapeutics , vol.11 , pp. 111-116
    • Payami, H.1    Factor, S.A.2
  • 3
    • 0033569516 scopus 로고    scopus 로고
    • Pharmacogenomics: Translating functional genomics into rational therapeutics
    • Evans, W. E., Relling, M. V. Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics. Science 286, 487-491 (1999).
    • (1999) Science , vol.286 , pp. 487-491
    • Evans, W.E.1    Relling, M.V.2
  • 4
    • 47249143688 scopus 로고    scopus 로고
    • Pharmacogenetics of aspirin resistance: A comprehensive systematic review
    • Goodman, T., Ferro, A., Sharma, P. Pharmacogenetics of aspirin resistance: a comprehensive systematic review. Br. J. Clin. Pharmacol. 66, 222-232 (2008).
    • (2008) Br. J. Clin. Pharmacol. , vol.66 , pp. 222-232
    • Goodman, T.1    Ferro, A.2    Sharma, P.3
  • 5
    • 34547469943 scopus 로고    scopus 로고
    • Pharmacogenetics and pharmacogenomics of schizophrenia: A review of last decade of research
    • Arranz, M. J., de Leon, J. Pharmacogenetics and pharmacogenomics of schizophrenia: a review of last decade of research. Mol. Psychiatry 12, 707-747 (2007).
    • (2007) Mol. Psychiatry , vol.12 , pp. 707-747
    • Arranz, M.J.1    De Leon, J.2
  • 6
    • 84857055178 scopus 로고    scopus 로고
    • Pharmacogenomics of antidepressant induced mania: A review and meta-analysis of the serotonin transporter gene (5HTTLPR) association
    • Biernacka, J. M. et al. Pharmacogenomics of antidepressant induced mania: A review and meta-analysis of the serotonin transporter gene (5HTTLPR) association. J. Affect. Disord. 136, e21-e29 (2012).
    • (2012) J. Affect. Disord. , vol.136 , pp. e21-e29
    • Biernacka, J.M.1
  • 7
    • 84866611528 scopus 로고    scopus 로고
    • Pharmacogenomics knowledge for personalized medicine
    • Whirl-Carrillo, M. et al. Pharmacogenomics knowledge for personalized medicine. Clin. Pharmacol. Ther. 92, 414-417 (2012).
    • (2012) Clin. Pharmacol. Ther. , vol.92 , pp. 414-417
    • Whirl-Carrillo, M.1
  • 8
    • 84891790401 scopus 로고    scopus 로고
    • The NHGRI GWAS Catalog, a curated resource of SNP-trait associations
    • Welter, D. et al. The NHGRI GWAS Catalog, a curated resource of SNP-trait associations. Nucleic Acids Res. 42, D1001-1006 (2014).
    • (2014) Nucleic Acids Res. , vol.42 , pp. D1001-1006
    • Welter, D.1
  • 9
    • 67651166638 scopus 로고    scopus 로고
    • Generating genome-scale candidate gene lists for pharmacogenomics
    • Hansen, N. T., Brunak, S., Altman, R. B. Generating genome-scale candidate gene lists for pharmacogenomics. Clin. Pharmacol. Ther. 86, 183-189 (2009).
    • (2009) Clin. Pharmacol. Ther. , vol.86 , pp. 183-189
    • Hansen, N.T.1    Brunak, S.2    Altman, R.B.3
  • 11
    • 84859169877 scopus 로고    scopus 로고
    • The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
    • Barretina, J. et al. The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature 483, 603-607 (2012).
    • (2012) Nature , vol.483 , pp. 603-607
    • Barretina, J.1
  • 12
    • 33749335282 scopus 로고    scopus 로고
    • The Connectivity Map: Using gene-expression signatures to connect small molecules, genes, and disease
    • Lamb, J. et al. The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Science 313, 1929-1935 (2006).
    • (2006) Science , vol.313 , pp. 1929-1935
    • Lamb, J.1
  • 13
    • 0033048778 scopus 로고    scopus 로고
    • Genomic profiling of drug sensitivities via induced haploinsufficiency
    • Giaever, G. et al. Genomic profiling of drug sensitivities via induced haploinsufficiency. Nat. Genet. 21, 278-283 (1999).
    • (1999) Nat. Genet. , vol.21 , pp. 278-283
    • Giaever, G.1
  • 15
    • 0347473810 scopus 로고    scopus 로고
    • Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways
    • Parsons, A. B. et al. Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways. Nat. Biotechnol. 22, 62-69 (2004).
    • (2004) Nat. Biotechnol. , vol.22 , pp. 62-69
    • Parsons, A.B.1
  • 16
    • 50849097234 scopus 로고    scopus 로고
    • Off-target effects of psychoactive drugs revealed by genome-wide assays in yeast
    • Ericson, E. et al. Off-Target Effects of Psychoactive Drugs Revealed by Genome-Wide Assays in Yeast. PLoS Genet 4, e1000151 (2008).
    • (2008) PLoS Genet , vol.4 , pp. e1000151
    • Ericson, E.1
  • 17
    • 42349100173 scopus 로고    scopus 로고
    • The chemical genomic portrait of yeast: Uncovering a phenotype for all genes
    • Hillenmeyer, M. E. et al. The chemical genomic portrait of yeast: uncovering a phenotype for all genes. Science 320, 362-365 (2008).
    • (2008) Science , vol.320 , pp. 362-365
    • Hillenmeyer, M.E.1
  • 18
    • 84897973939 scopus 로고    scopus 로고
    • Mapping the cellular response to small molecules using chemogenomic fitness signatures
    • Lee, A. Y. et al. Mapping the cellular response to small molecules using chemogenomic fitness signatures. Science 344, 208-211 (2014).
    • (2014) Science , vol.344 , pp. 208-211
    • Lee, A.Y.1
  • 19
    • 84891626273 scopus 로고    scopus 로고
    • High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions
    • Hoepfner, D. et al. High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions. Microbiol. Res. 169, 107-120 (2014).
    • (2014) Microbiol. Res. , vol.169 , pp. 107-120
    • Hoepfner, D.1
  • 20
    • 84891767304 scopus 로고    scopus 로고
    • DrugBank 4.0: Shedding new light on drug metabolism
    • Law, V. et al. DrugBank 4.0: shedding new light on drug metabolism. Nucleic Acids Res. 42, D1091-1097 (2014).
    • (2014) Nucleic Acids Res. , vol.42 , pp. D1091-1097
    • Law, V.1
  • 21
    • 75549091977 scopus 로고    scopus 로고
    • SMPDB: The Small Molecule Pathway Database
    • Frolkis, A. et al. SMPDB: The Small Molecule Pathway Database. Nucleic Acids Res. 38, D480-487 (2010).
    • (2010) Nucleic Acids Res. , vol.38 , pp. D480-487
    • Frolkis, A.1
  • 23
    • 3142519666 scopus 로고    scopus 로고
    • Pharmacogenetics of antidepressants and antipsychotics: The contribution of allelic variations to the phenotype of drug response
    • Kirchheiner, J. et al. Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response. Mol. Psychiatry 9, 442-473 (2004).
    • (2004) Mol. Psychiatry , vol.9 , pp. 442-473
    • Kirchheiner, J.1
  • 24
    • 84908067335 scopus 로고    scopus 로고
    • Which adverse effects influence the dropout rate in selective serotonin reuptake inhibitor (SSRI) treatment? Results for 50,824 patients
    • Kostev, K., Rex, J., Eith, T., Heilmaier, C. Which adverse effects influence the dropout rate in selective serotonin reuptake inhibitor (SSRI) treatment? Results for 50,824 patients. GMS Ger. Med. Sci. 12 (2014).
    • (2014) GMS Ger. Med. Sci. , vol.12
    • Kostev, K.1    Rex, J.2    Eith, T.3    Heilmaier, C.4
  • 25
    • 24944449979 scopus 로고    scopus 로고
    • Efficacy and safety of second-generation antidepressants in the treatment of major depressive disorder
    • Hansen, R. A., Gartlehner, G., Lohr, K. N., Gaynes, B. N., Carey, T. S. Efficacy and Safety of Second-Generation Antidepressants in the Treatment of Major Depressive Disorder. Ann. Intern. Med. 143, 415-426 (2005).
    • (2005) Ann. Intern. Med. , vol.143 , pp. 415-426
    • Hansen, R.A.1    Gartlehner, G.2    Lohr, K.N.3    Gaynes, B.N.4    Carey, T.S.5
  • 26
    • 33845968599 scopus 로고    scopus 로고
    • Switching antidepressants after a first selective serotonin reuptake inhibitor in major depressive disorder: A systematic review
    • Ruhé, H. G., Huyser, J., Swinkels, J. A., Schene, A. H. Switching antidepressants after a first selective serotonin reuptake inhibitor in major depressive disorder: a systematic review. J. Clin. Psychiatry 67, 1836-1855 (2006).
    • (2006) J. Clin. Psychiatry , vol.67 , pp. 1836-1855
    • Ruhé, H.G.1    Huyser, J.2    Swinkels, J.A.3    Schene, A.H.4
  • 27
    • 0034749036 scopus 로고    scopus 로고
    • Estrogen replacement therapy and antidepressant response to sertraline in older depressed women
    • Schneider, L. S., Small, G. W., Clary, C. M. Estrogen Replacement Therapy and Antidepressant Response to Sertraline in Older Depressed Women. Am. J. Geriatr. Psychiatry 9, 393-399 (2001).
    • (2001) Am. J. Geriatr. Psychiatry , vol.9 , pp. 393-399
    • Schneider, L.S.1    Small, G.W.2    Clary, C.M.3
  • 28
    • 12644318801 scopus 로고    scopus 로고
    • Estrogen replacement and response to fluoxetine in a multicenter geriatric depression trial
    • Schneider, L. S. et al. Estrogen Replacement and Response to Fluoxetine in a Multicenter Geriatric Depression Trial. Am. J. Geriatr. Psychiatry 5, 97-106 (1997).
    • (1997) Am. J. Geriatr. Psychiatry , vol.5 , pp. 97-106
    • Schneider, L.S.1
  • 29
    • 0032213226 scopus 로고    scopus 로고
    • Estrogen serotonin, and mood disturbance: Where is the therapeutic bridge?
    • Joffe, H., Cohen, L. S. Estrogen, serotonin, and mood disturbance: where is the therapeutic bridge? Biol. Psychiatry 44, 798-811 (1998).
    • (1998) Biol. Psychiatry , vol.44 , pp. 798-811
    • Joffe, H.1    Cohen, L.S.2
  • 30
    • 19944426724 scopus 로고    scopus 로고
    • Association of a corticotropin-releasing hormone receptor 1 haplotype and antidepressant treatment response in Mexican-Americans
    • Licinio, J. et al. Association of a corticotropin-releasing hormone receptor 1 haplotype and antidepressant treatment response in Mexican-Americans. Mol. Psychiatry 9, 1075-1082 (2004).
    • (2004) Mol. Psychiatry , vol.9 , pp. 1075-1082
    • Licinio, J.1
  • 31
    • 47749123329 scopus 로고    scopus 로고
    • Meta-analyses of genetic studies on major depressive disorder
    • López-León, S. et al. Meta-analyses of genetic studies on major depressive disorder. Mol. Psychiatry 13, 772-785 (2008).
    • (2008) Mol. Psychiatry , vol.13 , pp. 772-785
    • López-León, S.1
  • 32
    • 69549103060 scopus 로고    scopus 로고
    • Interaction of serotonin-related genes affects short-term antidepressant response in major depressive disorder
    • Lin, E. et al. Interaction of serotonin-related genes affects short-term antidepressant response in major depressive disorder. Prog. Neuropsychopharmacol. Biol. Psychiatry 33, 1167-1172 (2009).
    • (2009) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.33 , pp. 1167-1172
    • Lin, E.1
  • 33
    • 3442875285 scopus 로고    scopus 로고
    • The LATS2/KPM tumor suppressor is a negative regulator of the androgen receptor
    • Powzaniuk, M. et al. The LATS2/KPM tumor suppressor is a negative regulator of the androgen receptor. Mol. Endocrinol. Baltim. Md 18, 2011-2023 (2004).
    • (2004) Mol. Endocrinol. Baltim. Md , vol.18 , pp. 2011-2023
    • Powzaniuk, M.1
  • 34
    • 35848935069 scopus 로고    scopus 로고
    • DNA damage response mediators MDC1 and 53BP1: Constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours
    • Bartkova, J. et al. DNA damage response mediators MDC1 and 53BP1: constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours. Oncogene 26, 7414-7422 (2007).
    • (2007) Oncogene , vol.26 , pp. 7414-7422
    • Bartkova, J.1
  • 35
    • 79958715468 scopus 로고    scopus 로고
    • Mediator of DNA damage checkpoint protein 1 (MDC1) expression as a prognostic marker for nodal recurrence in early-stage breast cancer patients treated with breast-conserving surgery and radiation therapy
    • Patel, A. N. et al. Mediator of DNA damage checkpoint protein 1 (MDC1) expression as a prognostic marker for nodal recurrence in early-stage breast cancer patients treated with breast-conserving surgery and radiation therapy. Breast Cancer Res. Treat. 126, 601-607 (2011).
    • (2011) Breast Cancer Res. Treat. , vol.126 , pp. 601-607
    • Patel, A.N.1
  • 36
    • 49749151009 scopus 로고    scopus 로고
    • MicroRNA-34 mediates AR-dependent p53-induced apoptosis in prostate cancer
    • Rokhlin, O. W. et al. MicroRNA-34 mediates AR-dependent p53-induced apoptosis in prostate cancer. Cancer Biol. Ther. 7, 1288-1296 (2008).
    • (2008) Cancer Biol. Ther. , vol.7 , pp. 1288-1296
    • Rokhlin, O.W.1
  • 37
    • 78650631094 scopus 로고    scopus 로고
    • Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action
    • Kapitzky, L. et al. Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action. Mol. Syst. Biol. 6, 451 (2010).
    • (2010) Mol. Syst. Biol. , vol.6 , pp. 451
    • Kapitzky, L.1
  • 38
    • 35348988264 scopus 로고    scopus 로고
    • Mechanism-of-action determination of GMP synthase inhibitors and target validation in Candida albicans and Aspergillus fumigatus
    • Rodriguez-Suarez, R. et al. Mechanism-of-action determination of GMP synthase inhibitors and target validation in Candida albicans and Aspergillus fumigatus. Chem. Biol. 14, 1163-1175 (2007).
    • (2007) Chem. Biol. , vol.14 , pp. 1163-1175
    • Rodriguez-Suarez, R.1
  • 39
    • 31544450286 scopus 로고    scopus 로고
    • Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: The Keio collection
    • Baba, T. et al. Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol. Syst. Biol. 2, 2006-8 (2006).
    • (2006) Mol. Syst. Biol. , vol.2 , pp. 2006-2008
    • Baba, T.1
  • 41
    • 47649093352 scopus 로고    scopus 로고
    • An integrated platform of genomic assays reveals small-molecule bioactivities
    • Hoon, S. et al. An integrated platform of genomic assays reveals small-molecule bioactivities. Nat. Chem. Biol. 4, 498-506 (2008).
    • (2008) Nat. Chem. Biol. , vol.4 , pp. 498-506
    • Hoon, S.1
  • 42
    • 0031858914 scopus 로고    scopus 로고
    • SGD: Saccharomyces Genome Database
    • Cherry, J. M. et al. SGD: Saccharomyces Genome Database. Nucleic Acids Res. 26, 73-79 (1998).
    • (1998) Nucleic Acids Res. , vol.26 , pp. 73-79
    • Cherry, J.M.1
  • 43
    • 84891782659 scopus 로고    scopus 로고
    • Pfam: The protein families database
    • Finn, R. D. et al. Pfam: the protein families database. Nucleic Acids Res. 42, D222-D230 (2014).
    • (2014) Nucleic Acids Res. , vol.42 , pp. D222-D230
    • Finn, R.D.1
  • 44
    • 58549101103 scopus 로고    scopus 로고
    • A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes
    • Lage, K. et al. A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes. Proc. Natl. Acad. Sci. 105, 20870-20875 (2008).
    • (2008) Proc. Natl. Acad. Sci. , vol.105 , pp. 20870-20875
    • Lage, K.1
  • 45
    • 2542434304 scopus 로고    scopus 로고
    • Classification of drugs using the ATC system (Anatomic Therapeutic Chemical Classification) and the latest changes
    • Skrbo, A., Begovi?, B., Skrbo, S. [Classification of drugs using the ATC system (Anatomic, Therapeutic, Chemical Classification) and the latest changes]. Med. Arh. 58, 138-141 (2004).
    • (2004) Med. Arh. , vol.58 , pp. 138-141
    • Skrbo, A.1    Begovi, B.2    Skrbo, S.3
  • 46
    • 60849139395 scopus 로고    scopus 로고
    • GOrilla: A tool for discovery and visualization of enriched GO terms in ranked gene lists
    • Eden, E., Navon, R., Steinfeld, I., Lipson, D., Yakhini, Z. GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists. BMC Bioinformatics 10, 48 (2009).
    • (2009) BMC Bioinformatics , vol.10 , pp. 48
    • Eden, E.1    Navon, R.2    Steinfeld, I.3    Lipson, D.4    Yakhini, Z.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.