Blocking miRNA Biogenesis in Adult Forebrain Neurons Enhances Seizure Susceptibility, Fear Memory, and Food Intake by Increasing Neuronal Responsiveness

Cerebral Cortex

Volumn 26, Issue 4, 2016, Pages 1619-1633

  Fiorenza, Anna ^a   Lopez Atalaya, Jose P ^a   Rovira, Victor ^a   Scandaglia, Marilyn ^a   Geijo Barrientos, Emilio ^a   Barco, Angel ^a  

^a INSTITUTO DE NEUROCIENCIAS   (Spain)

Author keywords

activity driven transcription; Dicer; epilepsy; learning and memory; miRNAs; neuronal excitability; neuronal homeostasis; obesity; regulation of gene expression

Indexed keywords

DICER; DICER1; GLIAL FIBRILLARY ACIDIC PROTEIN; KAINIC ACID; MICRORNA; MICRORNA 124; RNA INDUCED SILENCING COMPLEX; UNCLASSIFIED DRUG; DEAD BOX PROTEIN; DICER1 PROTEIN, MOUSE; RIBONUCLEASE III;

ACTION POTENTIAL; ADULT; AFTERHYPERPOLARIZATION; ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARCUATE NUCLEUS; ARTICLE; BINDING SITE; BIOGENESIS; BODY WEIGHT; CARBOXY TERMINAL SEQUENCE; CEREBELLUM; CONTROLLED STUDY; DENTATE GYRUS; ESTROGEN BINDING; EXCITABILITY; EXON; FEAR; FEMALE; FOOD DEPRIVATION; FOOD INTAKE; FOREBRAIN; GENE EXPRESSION; GENETIC MANIPULATION; GRANULE CELL; HIPPOCAMPAL CA1 REGION; HIPPOCAMPUS; HOMEOSTASIS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MEMORY; MOUSE; NERVE CELL; NERVE CELL PLASTICITY; NERVE DEGENERATION; NERVE FIBER GROWTH; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; PYRAMIDAL NERVE CELL; SEIZURE SUSCEPTIBILITY; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; C57BL MOUSE; CHEMICALLY INDUCED; CONDITIONED REFLEX; GENETICS; HYPERPHAGIA; KNOCKOUT MOUSE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; SEIZURE; SEQUENCE ANALYSIS;

ACTION POTENTIALS; ANIMALS; CA1 REGION, HIPPOCAMPAL; CONDITIONING, CLASSICAL; DEAD-BOX RNA HELICASES; FEAR; FEMALE; HYPERPHAGIA; KAINIC ACID; MALE; MEMORY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICRORNAS; NEURONAL PLASTICITY; NEURONS; PHENOTYPE; PROSENCEPHALON; RIBONUCLEASE III; SEIZURES; SEQUENCE ANALYSIS, RNA;

EID: 84963800578     PISSN: 10473211     EISSN: 14602199     Source Type: Journal    
DOI: 10.1093/cercor/bhu332     Document Type: Article

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