Timing specific requirement of microRNA function is essential for embryonic and postnatal hippocampal development

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Li, Qingsong ^a,b   Bian, Shan ^a   Hong, Janet ^a   Kawase Koga, Yoko ^c   Zhu, Edwin ^d   Zheng, Yongri ^b   Yang, Lizhuang ^b   Sun, Tao ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b HARBIN MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF TOKYO HOSPITAL   (Japan)

^d NEW YORK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; DICER; MICRORNA; RIBONUCLEASE III; UNTRANSLATED RNA; BIOLOGICAL MARKER;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN DEVELOPMENT; BRAIN FUNCTION; BRAIN NERVE CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DENTATE GYRUS; EMBRYO DEVELOPMENT; GENE FUNCTION; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA2 REGION; HIPPOCAMPAL CA3 REGION; HIPPOCAMPUS; LEARNING; MEMORY; MOUSE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NEUROEPITHELIUM; NONHUMAN; POSTNATAL DEVELOPMENT; ANIMAL; BIOLOGICAL MODEL; BIOSYNTHESIS; CELL COUNT; CELL DEATH; CELL MOTION; CYTOLOGY; GENE DELETION; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MOUSE MUTANT; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NEWBORN; PRENATAL DEVELOPMENT; TIME;

MUS;

ANIMALS; ANIMALS, NEWBORN; BIOLOGICAL MARKERS; CELL COUNT; CELL DEATH; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; EMBRYONIC DEVELOPMENT; GENE DELETION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKOUT TECHNIQUES; HIPPOCAMPUS; MICE; MICE, KNOCKOUT; MICRORNAS; MODELS, BIOLOGICAL; NEURAL STEM CELLS; NEUROGENESIS; NEURONS; RIBONUCLEASE III; TIME FACTORS;

EID: 80053466640     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026000     Document Type: Article

References (38)

1. Eriksson PS, Perfilieva E, Bjork-Eriksson T, Alborn AM, Nordborg C, et al. (1998) Neurogenesis in the adult human hippocampus. Nat Med 4: 1313-1317.
2. Alvarez-Buylla A, Temple S, (1998) Stem cells in the developing and adult nervous system. J Neurobiol 36: 105-110.
3. Eisch AJ, Cameron HA, Encinas JM, Meltzer LA, Ming GL, et al. (2008) Adult neurogenesis, mental health, and mental illness: hope or hype? J Neurosci 28: 11785-11791.
4. Deng W, Aimone JB, Gage FH, (2010) New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? Nat Rev Neurosci 11: 339-350.
5. Li G, Pleasure SJ, (2007) Genetic regulation of dentate gyrus morphogenesis. Prog Brain Res 163: 143-152.
6. Li G, Pleasure SJ, (2005) Morphogenesis of the dentate gyrus: what we are learning from mouse mutants. Dev Neurosci 27: 93-99.
7. Grove EA, Tole S, Limon J, Yip L, Ragsdale CW, (1998) The hem of the embryonic cerebral cortex is defined by the expression of multiple Wnt genes and is compromised in Gli3-deficient mice. Development 125: 2315-2325.
8. Monuki ES, Porter FD, Walsh CA, (2001) Patterning of the dorsal telencephalon and cerebral cortex by a roof plate-Lhx2 pathway. Neuron 32: 591-604.
9. Bagri A, Gurney T, He X, Zou YR, Littman DR, et al. (2002) The chemokine SDF1 regulates migration of dentate granule cells. Development 129: 4249-4260.
10. Furuta Y, Piston DW, Hogan BL, (1997) Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development. Development 124: 2203-2212.
11. Mangale VS, Hirokawa KE, Satyaki PR, Gokulchandran N, Chikbire S, et al. (2008) Lhx2 selector activity specifies cortical identity and suppresses hippocampal organizer fate. Science 319: 304-309.
12. Galceran J, Miyashita-Lin EM, Devaney E, Rubenstein JL, Grosschedl R, (2000) Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1. Development 127: 469-482.
13. Lee SM, Tole S, Grove E, McMahon AP, (2000) A local Wnt-3a signal is required for development of the mammalian hippocampus. Development 127: 457-467.
14. Pellegrini M, Mansouri A, Simeone A, Boncinelli E, Gruss P, (1996) Dentate gyrus formation requires Emx2. Development 122: 3893-3898.
15. Yoshida M, Suda Y, Matsuo I, Miyamoto N, Takeda N, et al. (1997) Emx1 and Emx2 functions in development of dorsal telencephalon. Development 124: 101-111.
16. Zhao Y, Sheng HZ, Amini R, Grinberg A, Lee E, et al. (1999) Control of hippocampal morphogenesis and neuronal differentiation by the LIM homeobox gene Lhx5. Science 284: 1155-1158.
17. Lee RC, Feinbaum RL, Ambros V, (1993) The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75: 843-854.
18. Wightman B, Ha I, Ruvkun G, (1993) Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75: 855-862.
19. Kim VN, (2004) MicroRNA precursors in motion: exportin-5 mediates their nuclear export. Trends Cell Biol 14: 156-159.
20. Hammond SM, (2005) Dicing and slicing: the core machinery of the RNA interference pathway. FEBS Lett 579: 5822-5829.
21. Kim VN, Han J, Siomi MC, (2009) Biogenesis of small RNAs in animals. Nat Rev Mol Cell Biol 10: 126-139.
22. Carthew RW, Sontheimer EJ, (2009) Origins and Mechanisms of miRNAs and siRNAs. Cell 136: 642-655.
23. De Pietri Tonelli D, Pulvers JN, Haffner C, Murchison EP, Hannon GJ, et al. (2008) miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex. Development 135: 3911-3921.
24. Kawase-Koga Y, Otaegi G, Sun T, (2009) Different timings of dicer deletion affect neurogenesis and gliogenesis in the developing mouse central nervous system. Dev Dyn 238: 2800-2812.
25. Huang T, Liu Y, Huang M, Zhao X, Cheng L, (2010) Wnt1-cre-mediated conditional loss of Dicer results in malformation of the midbrain and cerebellum and failure of neural crest and dopaminergic differentiation in mice. J Mol Cell Biol 2: 152-163.
26. Kawase-Koga Y, Low R, Otaegi G, Pollock A, Deng H, et al. (2010) RNAase-III enzyme Dicer maintains signaling pathways for differentiation and survival in mouse cortical neural stem cells. J Cell Sci 123: 586-594.
27. Andersson T, Rahman S, Sansom SN, Alsio JM, Kaneda M, et al. (2010) Reversible block of mouse neural stem cell differentiation in the absence of dicer and microRNAs. PLoS One 5: e13453.
28. Davis TH, Cuellar TL, Koch SM, Barker AJ, Harfe BD, et al. (2008) Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus. J Neurosci 28: 4322-4330.
29. Hebert SS, Papadopoulou AS, Smith P, Galas MC, Planel E, et al. (2010) Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration. Hum Mol Genet 19: 3959-3969.
30. Konopka W, Kiryk A, Novak M, Herwerth M, Parkitna JR, et al. (2010) MicroRNA loss enhances learning and memory in mice. J Neurosci 30: 14835-14842.
31. Gorski JA, Talley T, Qiu M, Puelles L, Rubenstein JL, et al. (2002) Cortical excitatory neurons and glia, but not GABAergic neurons, are produced in the Emx1-expressing lineage. J Neurosci 22: 6309-6314.
32. Tronche F, Kellendonk C, Kretz O, Gass P, Anlag K, et al. (1999) Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety. Nat Genet 23: 99-103.
33. Cecchi C, Boncinelli E, (2000) Emx homeogenes and mouse brain development. Trends Neurosci 23: 347-352.
34. Goebbels S, Bormuth I, Bode U, Hermanson O, Schwab MH, et al. (2006) Genetic targeting of principal neurons in neocortex and hippocampus of NEX-Cre mice. Genesis 44: 611-621.
35. Bulchand S, Grove EA, Porter FD, Tole S, (2001) LIM-homeodomain gene Lhx2 regulates the formation of the cortical hem. Mech Dev 100: 165-175.
36. Murchison EP, Partridge JF, Tam OH, Cheloufi S, Hannon GJ, (2005) Characterization of Dicer-deficient murine embryonic stem cells. Proc Natl Acad Sci U S A 102: 12135-12140.
37. Sun T, Jayatilake D, Afink GB, Ataliotis P, Nister M, et al. (2000) A human YAC transgene rescues craniofacial and neural tube development in PDGFRalpha knockout mice and uncovers a role for PDGFRalpha in prenatal lung growth. Development 127: 4519-4529.
38. Obernosterer G, Martinez J, Alenius M, (2007) Locked nucleic acid-based in situ detection of microRNAs in mouse tissue sections. Nat Protoc 2: 1508-1514.