MiRNAs are required for generating a time delay critical for the circadian oscillator

Current Biology

Volumn 23, Issue 20, 2013, Pages 1959-1968

  Chen, Rongmin ^a   D'Alessandro, Matthew ^a   Lee, Choogon ^a  

^a FLORIDA STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIA; MUS;

CIRCADIAN RHYTHM SIGNALING PROTEIN; MICRORNA; PER1 PROTEIN, MOUSE; PER2 PROTEIN, MOUSE;

ANIMAL; CIRCADIAN RHYTHM; GENE EXPRESSION REGULATION; GENETICS; IMMUNOBLOTTING; METABOLISM; MOUSE; MUTANT MOUSE STRAIN; POLYMERASE CHAIN REACTION; RNA INTERFERENCE;

ANIMALS; CIRCADIAN CLOCKS; GENE EXPRESSION REGULATION; IMMUNOBLOTTING; MICE; MICE, MUTANT STRAINS; MICRORNAS; PERIOD CIRCADIAN PROTEINS; POLYMERASE CHAIN REACTION; RNA INTERFERENCE;

EID: 84886240503     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2013.08.005     Document Type: Article

References (59)

1. S.M. Reppert, and D.R. Weaver Coordination of circadian timing in mammals Nature 418 2002 935 941
2. U. Schibler The daily rhythms of genes, cells and organs. Biological clocks and circadian timing in cells EMBO Rep. 6 Spec No 2005 S9 S13
3. J.A. Mohawk, C.B. Green, and J.S. Takahashi Central and peripheral circadian clocks in mammals Annu. Rev. Neurosci. 35 2012 445 462
4. D.K. Welsh, S.H. Yoo, A.C. Liu, J.S. Takahashi, and S.A. Kay Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression Curr. Biol. 14 2004 2289 2295
5. S.H. Yoo, S. Yamazaki, P.L. Lowrey, K. Shimomura, C.H. Ko, E.D. Buhr, S.M. Siepka, H.K. Hong, W.J. Oh, and O.J. Yoo PERIOD2:LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues Proc. Natl. Acad. Sci. USA 101 2004 5339 5346
6. K. Yagita, F. Tamanini, G.T. van Der Horst, and H. Okamura Molecular mechanisms of the biological clock in cultured fibroblasts Science 292 2001 278 281
7. A.C. Liu, D.K. Welsh, C.H. Ko, H.G. Tran, E.E. Zhang, A.A. Priest, E.D. Buhr, O. Singer, K. Meeker, and I.M. Verma Intercellular coupling confers robustness against mutations in the SCN circadian clock network Cell 129 2007 605 616
8. R. Chen, A. Schirmer, Y. Lee, H. Lee, V. Kumar, S.H. Yoo, J.S. Takahashi, and C. Lee Rhythmic PER abundance defines a critical nodal point for negative feedback within the circadian clock mechanism Mol. Cell 36 2009 417 430
9. E.E. Zhang, A.C. Liu, T. Hirota, L.J. Miraglia, G. Welch, P.Y. Pongsawakul, X. Liu, A. Atwood, J.W. Huss 3rd, and J. Janes A genome-wide RNAi screen for modifiers of the circadian clock in human cells Cell 139 2009 199 210
10. G.T. van der Horst, M. Muijtjens, K. Kobayashi, R. Takano, S. Kanno, M. Takao, J. de Wit, A. Verkerk, A.P. Eker, and D. van Leenen Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms Nature 398 1999 627 630
11. R. Allada, P. Emery, J.S. Takahashi, and M. Rosbash Stopping time: the genetics of fly and mouse circadian clocks Annu. Rev. Neurosci. 24 2001 1091 1119
12. W. Yu, and P.E. Hardin Circadian oscillators of Drosophila and mammals J. Cell Sci. 119 2006 4793 4795
13. P.E. Hardin, J.C. Hall, and M. Rosbash Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels Nature 343 1990 536 540
14. C. Lee, D.R. Weaver, and S.M. Reppert Direct association between mouse PERIOD and CKIepsilon is critical for a functioning circadian clock Mol. Cell. Biol. 24 2004 584 594
15. K. Kume, M.J. Zylka, S. Sriram, L.P. Shearman, D.R. Weaver, X. Jin, E.S. Maywood, M.H. Hastings, and S.M. Reppert mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop Cell 98 1999 193 205
16. E.A. Griffin Jr., D. Staknis, and C.J. Weitz Light-independent role of CRY1 and CRY2 in the mammalian circadian clock Science 286 1999 768 771
17. H. Cho, X. Zhao, M. Hatori, R.T. Yu, G.D. Barish, M.T. Lam, L.W. Chong, L. DiTacchio, A.R. Atkins, and C.K. Glass Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β Nature 485 2012 123 127
18. N. Preitner, F. Damiola, L. Lopez-Molina, J. Zakany, D. Duboule, U. Albrecht, and U. Schibler The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator Cell 110 2002 251 260
19. T.K. Sato, S. Panda, L.J. Miraglia, T.M. Reyes, R.D. Rudic, P. McNamara, K.A. Naik, G.A. FitzGerald, S.A. Kay, and J.B. Hogenesch A functional genomics strategy reveals Rora as a component of the mammalian circadian clock Neuron 43 2004 527 537
20. H.R. Ueda, W. Chen, A. Adachi, H. Wakamatsu, S. Hayashi, T. Takasugi, M. Nagano, K. Nakahama, Y. Suzuki, and S. Sugano A transcription factor response element for gene expression during circadian night Nature 418 2002 534 539
21. Y. Shigeyoshi, K. Taguchi, S. Yamamoto, S. Takekida, L. Yan, H. Tei, T. Moriya, S. Shibata, J.J. Loros, J.C. Dunlap, and H. Okamura Light-induced resetting of a mammalian circadian clock is associated with rapid induction of the mPer1 transcript Cell 91 1997 1043 1053
22. L.P. Shearman, M.J. Zylka, D.R. Weaver, L.F. Kolakowski Jr., and S.M. Reppert Two period homologs: circadian expression and photic regulation in the suprachiasmatic nuclei Neuron 19 1997 1261 1269
23. K.L. Toh, C.R. Jones, Y. He, E.J. Eide, W.A. Hinz, D.M. Virshup, L.J. Ptácek, and Y.H. Fu An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome Science 291 2001 1040 1043
24. C. Lee, J.P. Etchegaray, F.R. Cagampang, A.S. Loudon, and S.M. Reppert Posttranslational mechanisms regulate the mammalian circadian clock Cell 107 2001 855 867
25. J.L. Price, J. Blau, A. Rothenfluh, M. Abodeely, B. Kloss, and M.W. Young double-time is a novel Drosophila clock gene that regulates PERIOD protein accumulation Cell 94 1998 83 95
26. P.L. Lowrey, K. Shimomura, M.P. Antoch, S. Yamazaki, P.D. Zemenides, M.R. Ralph, M. Menaker, and J.S. Takahashi Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau Science 288 2000 483 492
27. J.C. Chiu, J.T. Vanselow, A. Kramer, and I. Edery The phospho-occupancy of an atypical SLIMB-binding site on PERIOD that is phosphorylated by DOUBLETIME controls the pace of the clock Genes Dev. 22 2008 1758 1772
28. H.W. Ko, J. Jiang, and I. Edery Role for Slimb in the degradation of Drosophila Period protein phosphorylated by Doubletime Nature 420 2002 673 678
29. H.M. Lee, R. Chen, H. Kim, J.P. Etchegaray, D.R. Weaver, and C. Lee The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1 Proc. Natl. Acad. Sci. USA 108 2011 16451 16456
30. S.M. Reppert, and D.R. Weaver Molecular analysis of mammalian circadian rhythms Annu. Rev. Physiol. 63 2001 647 676
31. D.P. Bartel MicroRNAs: genomics, biogenesis, mechanism, and function Cell 116 2004 281 297
32. R.W. Carthew, and E.J. Sontheimer Origins and Mechanisms of miRNAs and siRNAs Cell 136 2009 642 655
33. B.P. Lewis, C.B. Burge, and D.P. Bartel Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets Cell 120 2005 15 20
34. G. Stefani, and F.J. Slack Small non-coding RNAs in animal development Nat. Rev. Mol. Cell Biol. 9 2008 219 230
35. K.F. Hansen, K. Sakamoto, and K. Obrietan MicroRNAs: a potential interface between the circadian clock and human health Genome Med 3 2011 10
36. H.Y. Cheng, J.W. Papp, O. Varlamova, H. Dziema, B. Russell, J.P. Curfman, T. Nakazawa, K. Shimizu, H. Okamura, S. Impey, and K. Obrietan microRNA modulation of circadian-clock period and entrainment Neuron 54 2007 813 829
37. S. Kadener, J.S. Menet, K. Sugino, M.D. Horwich, U. Weissbein, P. Nawathean, V.V. Vagin, P.D. Zamore, S.B. Nelson, and M. Rosbash A role for microRNAs in the Drosophila circadian clock Genes Dev. 23 2009 2179 2191
38. V.R. Shende, M.M. Goldrick, S. Ramani, and D.J. Earnest Expression and rhythmic modulation of circulating microRNAs targeting the clock gene Bmal1 in mice PLoS ONE 6 2011 e22586
39. R. Nagel, L. Clijsters, and R. Agami The miRNA-192/194 cluster regulates the Period gene family and the circadian clock FEBS J. 276 2009 5447 5455
40. C. Siré, A.B. Moreno, M. Garcia-Chapa, J.J. López-Moya, and B. San Segundo Diurnal oscillation in the accumulation of Arabidopsis microRNAs, miR167, miR168, miR171 and miR398 FEBS Lett. 583 2009 1039 1044
41. W. Luo, and A. Sehgal Regulation of circadian behavioral output via a MicroRNA-JAK/STAT circuit Cell 148 2012 765 779
42. B.D. Harfe, M.T. McManus, J.H. Mansfield, E. Hornstein, and C.J. Tabin The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb Proc. Natl. Acad. Sci. USA 102 2005 10898 10903
43. S. Hayashi, and A.P. McMahon Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse Dev. Biol. 244 2002 305 318
44. J.P. Etchegaray, K.K. Machida, E. Noton, C.M. Constance, R. Dallmann, M.N. Di Napoli, J.P. DeBruyne, C.M. Lambert, E.A. Yu, S.M. Reppert, and D.R. Weaver Casein kinase 1 delta regulates the pace of the mammalian circadian clock Mol. Cell. Biol. 29 2009 3853 3866
45. Y. Tay, J. Zhang, A.M. Thomson, B. Lim, and I. Rigoutsos MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation Nature 455 2008 1124 1128
46. J.J. Forman, A. Legesse-Miller, and H.A. Coller A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence Proc. Natl. Acad. Sci. USA 105 2008 14879 14884
47. H. Lee, R. Chen, Y. Lee, S. Yoo, and C. Lee Essential roles of CKIdelta and CKIepsilon in the mammalian circadian clock Proc. Natl. Acad. Sci. USA 106 2009 21359 21364
48. M.J. Muskus, F. Preuss, J.Y. Fan, E.S. Bjes, and J.L. Price Drosophila DBT lacking protein kinase activity produces long-period and arrhythmic circadian behavioral and molecular rhythms Mol. Cell. Biol. 27 2007 8049 8064
49. E.M. Smith, J.M. Lin, R.A. Meissner, and R. Allada Dominant-negative CK2alpha induces potent effects on circadian rhythmicity PLoS Genet. 4 2008 e12
50. M. Petersen, and J. Wengel LNA: a versatile tool for therapeutics and genomics Trends Biotechnol. 21 2003 74 81
51. S.S. Low-Zeddies, and J.S. Takahashi Chimera analysis of the Clock mutation in mice shows that complex cellular integration determines circadian behavior Cell 105 2001 25 42
52. P.E. Hardin The circadian timekeeping system of Drosophila Curr. Biol. 15 2005 R714 R722
53. Y. Xu, K.L. Toh, C.R. Jones, J.Y. Shin, Y.H. Fu, and L.J. Ptácek Modeling of a human circadian mutation yields insights into clock regulation by PER2 Cell 128 2007 59 70
54. B.J. Reinhart, F.J. Slack, M. Basson, A.E. Pasquinelli, J.C. Bettinger, A.E. Rougvie, H.R. Horvitz, and G. Ruvkun The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans Nature 403 2000 901 906
55. S. Yekta, I.H. Shih, and D.P. Bartel MicroRNA-directed cleavage of HOXB8 mRNA Science 304 2004 594 596
56. H.K. Hong, J.L. Chong, W. Song, E.J. Song, A.A. Jyawook, A.C. Schook, C.H. Ko, and J.S. Takahashi Inducible and reversible Clock gene expression in brain using the tTA system for the study of circadian behavior PLoS Genet. 3 2007 e33
57. S.Y. Corbel, and F.M. Rossi Latest developments and in vivo use of the Tet system: ex vivo and in vivo delivery of tetracycline-regulated genes Curr. Opin. Biotechnol. 13 2002 448 452
58. R. Chen, D.O. Seo, E. Bell, C. von Gall, and C. Lee Strong resetting of the mammalian clock by constant light followed by constant darkness J. Neurosci. 28 2008 11839 11847
59. Q.J. Meng, L. Logunova, E.S. Maywood, M. Gallego, J. Lebiecki, T.M. Brown, M. Sládek, A.S. Semikhodskii, N.R. Glossop, and H.D. Piggins Setting clock speed in mammals: the CK1 epsilon tau mutation in mice accelerates circadian pacemakers by selectively destabilizing PERIOD proteins Neuron 58 2008 78 88