-
1
-
-
79951992387
-
AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training
-
CrossRef Medline
-
Aponte Y, Atasoy D, Sternson SM (2011) AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training. Nat Neurosci 14:351-355. CrossRef Medline
-
(2011)
Nat Neurosci
, vol.14
, pp. 351-355
-
-
Aponte, Y.1
Atasoy, D.2
Sternson, S.M.3
-
2
-
-
84864711337
-
Deconstruction of a neural circuit for hunger
-
CrossRef Medline
-
Atasoy D., Betley JN, Su HH, Sternson SM (2012) Deconstruction of a neural circuit for hunger. Nature 488:172-177. CrossRef Medline
-
(2012)
Nature
, vol.488
, pp. 172-177
-
-
Atasoy, D.1
Betley, J.N.2
Su, H.H.3
Sternson, S.M.4
-
3
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
CrossRef Medline
-
Bartel D. P (2009) MicroRNAs: target recognition and regulatory functions. Cell 136:215-233. CrossRef Medline
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
4
-
-
78649466467
-
CNS leptin and insulin action in the control of energy homeostasis
-
CrossRef Medline
-
Belgardt B. F, Brüning JC (2010) CNS leptin and insulin action in the control of energy homeostasis. Ann N Y Acad Sci 1212:97-113. CrossRef Medline
-
(2010)
Ann N Y Acad Sci
, vol.1212
, pp. 97-113
-
-
Belgardt, B.F.1
Brüning, J.C.2
-
5
-
-
70649092451
-
Hormone and glucose signalling in POMC and AgRP neurons
-
CrossRef Medline
-
Belgardt B. F, Okamura T, Brüning JC (2009) Hormone and glucose signalling in POMC and AgRP neurons. J Physiol 587:5305-5314. CrossRef Medline
-
(2009)
J Physiol
, vol.587
, pp. 5305-5314
-
-
Belgardt, B.F.1
Okamura, T.2
Brüning, J.C.3
-
6
-
-
84865798995
-
Metformin elicits anticancer effects through the sequential modulation of DICER and c-MYC
-
CrossRef Medline
-
Blandino G., Valerio M, Cioce M, Mori F, Casadei L, Pulito C, Sacconi A, Biagioni F., Cortese G, Galanti S, Manetti C, Citro G, Muti P, Strano S (2012) Metformin elicits anticancer effects through the sequential modulation of DICER and c-MYC. Nat Commun 3:865. CrossRef Medline
-
(2012)
Nat Commun
, vol.3
, pp. 865
-
-
Blandino, G.1
Valerio, M.2
Cioce, M.3
Mori, F.4
Casadei, L.5
Pulito, C.6
Sacconi, A.7
Biagioni, F.8
Cortese, G.9
Galanti, S.10
Manetti, C.11
Citro, G.12
Muti, P.13
Strano, S.14
-
7
-
-
20844432885
-
T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer
-
CrossRef Medline
-
Cobb B. S, Nesterova TB, Thompson E, Hertweck A, O'Connor E, Godwin J, Wilson C. B, Brockdorff N, Fisher AG, Smale ST, Merkenschlager M (2005) T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer. J Exp Med 201:1367-1373. CrossRef Medline
-
(2005)
J Exp Med
, vol.201
, pp. 1367-1373
-
-
Cobb, B.S.1
Nesterova, T.B.2
Thompson, E.3
Hertweck, A.4
O'Connor, E.5
Godwin, J.6
Wilson, C.B.7
Brockdorff, N.8
Fisher, A.G.9
Smale, S.T.10
Merkenschlager, M.11
-
8
-
-
0037663884
-
Caveolin-1-deficient mice show insulin resistance and defective insulin receptor protein expression in adipose tissue
-
CrossRef Medline
-
Cohen A. W, Razani B, Wang XB, Combs TP, Williams TM, Scherer PE, Lisanti M. P (2003) Caveolin-1-deficient mice show insulin resistance and defective insulin receptor protein expression in adipose tissue. Am J Physiol Cell Physiol 285:C222-C235. CrossRef Medline
-
(2003)
Am J Physiol Cell Physiol
, vol.285
-
-
Cohen, A.W.1
Razani, B.2
Wang, X.B.3
Combs, T.P.4
Williams, T.M.5
Scherer, P.E.6
Lisanti, M.P.7
-
9
-
-
33646582664
-
Hypothalamic mTOR signaling regulates food intake
-
CrossRef Medline
-
Cota D., Proulx K, Smith KA, Kozma SC, Thomas G, Woods SC, Seeley RJ (2006) Hypothalamic mTOR signaling regulates food intake. Science 312:927-930. CrossRef Medline
-
(2006)
Science
, vol.312
, pp. 927-930
-
-
Cota, D.1
Proulx, K.2
Smith, K.A.3
Kozma, S.C.4
Thomas, G.5
Woods, S.C.6
Seeley, R.J.7
-
10
-
-
80355135133
-
Construction and implantation of a microinfusion system for sustained delivery of neuroactive agents
-
CrossRef Medline
-
Cunningham M. G, O'Connor RP, Wong SE (2008) Construction and implantation of a microinfusion system for sustained delivery of neuroactive agents. J Vis Exp pii:716. CrossRef Medline
-
(2008)
J Vis Exp
, pp. 716
-
-
Cunningham, M.G.1
O'Connor, R.P.2
Wong, S.E.3
-
11
-
-
80052668585
-
Pten ablation in adult dopaminergic neurons is neuroprotective in Parkinson's disease models
-
CrossRef Medline
-
Domanskyi A., Geissler C, Vinnikov IA, Alter H, Schober A, Vogt MA, Gass P, Parlato R., Schütz G (2011) Pten ablation in adult dopaminergic neurons is neuroprotective in Parkinson's disease models. FASEB J 25:2898-2910. CrossRef Medline
-
(2011)
FASEB J
, vol.25
, pp. 2898-2910
-
-
Domanskyi, A.1
Geissler, C.2
Vinnikov, I.A.3
Alter, H.4
Schober, A.5
Vogt, M.A.6
Gass, P.7
Parlato, R.8
Schütz, G.9
-
12
-
-
13744250159
-
Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality
-
CrossRef Medline
-
Elmén J., Thonberg H, Ljungberg K, Frieden M, Westergaard M, Xu Y, Wahren B, Liang Z, Ørum H, Koch T, Wahlestedt C (2005) Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality. Nucleic Acids Res 33:439-447. CrossRef Medline
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 439-447
-
-
Elmén, J.1
Thonberg, H.2
Ljungberg, K.3
Frieden, M.4
Westergaard, M.5
Xu, Y.6
Wahren, B.7
Liang, Z.8
Ørum, H.9
Koch, T.10
Wahlestedt, C.11
-
13
-
-
0033082380
-
From lesions to leptin: Hypothalamic control of food intake and body weight
-
CrossRef Medline
-
Elmquist J. K, Elias CF, Saper CB (1999) From lesions to leptin: hypothalamic control of food intake and body weight. Neuron 22:221-232. CrossRef Medline
-
(1999)
Neuron
, vol.22
, pp. 221-232
-
-
Elmquist, J.K.1
Elias, C.F.2
Saper, C.B.3
-
14
-
-
34548356529
-
Inducible gene inactivation in neurons of the adult mouse forebrain
-
CrossRef Medline
-
Erdmann G., Schütz G, Berger S (2007) Inducible gene inactivation in neurons of the adult mouse forebrain. BMC Neurosci 8:63. CrossRef Medline
-
(2007)
BMC Neurosci
, vol.8
, pp. 63
-
-
Erdmann, G.1
Schütz, G.2
Berger, S.3
-
15
-
-
0029804743
-
Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y
-
CrossRef Medline
-
Erickson J. C, Hollopeter G, Palmiter RD (1996) Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y. Science 274:1704-1707. CrossRef Medline
-
(1996)
Science
, vol.274
, pp. 1704-1707
-
-
Erickson, J.C.1
Hollopeter, G.2
Palmiter, R.D.3
-
16
-
-
79951558318
-
National, regional, and global trends in body-mass index since 1980: Systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9.1 million participants
-
CrossRef Medline
-
Finucane M. M, Stevens GA, Cowan MJ, Danaei G, Lin JK, Paciorek CJ, Singh GM, Gutierrez HR, Lu Y, Bahalim AN, Farzadfar F, Riley LM, Ezzati M, Ezzati M. (2011) National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9.1 million participants. Lancet 377:557-567. CrossRef Medline
-
(2011)
Lancet
, vol.377
, pp. 557-567
-
-
Finucane, M.M.1
Stevens, G.A.2
Cowan, M.J.3
Danaei, G.4
Lin, J.K.5
Paciorek, C.J.6
Singh, G.M.7
Gutierrez, H.R.8
Lu, Y.9
Bahalim, A.N.10
Farzadfar, F.11
Riley, L.M.12
Ezzati, M.13
Ezzati, M.14
-
17
-
-
0032558725
-
Leptin and the regulation of body weight in mammals
-
CrossRef Medline
-
Friedman J. M, Halaas JL (1998) Leptin and the regulation of body weight in mammals. Nature 395:763-770. CrossRef Medline
-
(1998)
Nature
, vol.395
, pp. 763-770
-
-
Friedman, J.M.1
Halaas, J.L.2
-
18
-
-
35148839928
-
PI3Kgamma is a key regulator of inflammatory responses and cardiovascular homeostasis
-
CrossRef Medline
-
Hawkins P. T, Stephens LR (2007) PI3Kgamma is a key regulator of inflammatory responses and cardiovascular homeostasis. Science 318:64-66. CrossRef Medline
-
(2007)
Science
, vol.318
, pp. 64-66
-
-
Hawkins, P.T.1
Stephens, L.R.2
-
19
-
-
77950264425
-
Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility
-
CrossRef Medline
-
Hill J. W, Elias CF, Fukuda M, Williams KW, Berglund ED, Holland WL, Cho YR, Chuang JC, Xu Y, Choi M, Lauzon D, Lee CE, Coppari R, Richardson JA, Zigman JM, Chua S, Scherer PE, Lowell BB, Brüning JC, Elmquist JK (2010) Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility. Cell Metab 11:286-297. CrossRef Medline
-
(2010)
Cell Metab
, vol.11
, pp. 286-297
-
-
Hill, J.W.1
Elias, C.F.2
Fukuda, M.3
Williams, K.W.4
Berglund, E.D.5
Holland, W.L.6
Cho, Y.R.7
Chuang, J.C.8
Xu, Y.9
Choi, M.10
Lauzon, D.11
Lee, C.E.12
Coppari, R.13
Richardson, J.A.14
Zigman, J.M.15
Chua, S.16
Scherer, P.E.17
Lowell, B.B.18
Brüning, J.C.19
Elmquist, J.K.20
more..
-
20
-
-
35948934636
-
Activated protein C protects against diabetic nephropathy by inhibiting endothelial and podocyte apoptosis
-
CrossRef Medline
-
Isermann B., Vinnikov IA, Madhusudhan T, Herzog S, Kashif M, Blautzik J, Corat M. A, Zeier M, Blessing E, Oh J, Gerlitz B, Berg DT, Grinnell BW, Chavakis T., Esmon CT, Weiler H, Bierhaus A, Nawroth PP (2007) Activated protein C protects against diabetic nephropathy by inhibiting endothelial and podocyte apoptosis. Nat Med 13:1349-1358. CrossRef Medline
-
(2007)
Nat Med
, vol.13
, pp. 1349-1358
-
-
Isermann, B.1
Vinnikov, I.A.2
Madhusudhan, T.3
Herzog, S.4
Kashif, M.5
Blautzik, J.6
Corat, M.A.7
Zeier, M.8
Blessing, E.9
Oh, J.10
Gerlitz, B.11
Berg, D.T.12
Grinnell, B.W.13
Chavakis, T.14
Esmon, C.T.15
Weiler, H.16
Bierhaus, A.17
Nawroth, P.P.18
-
21
-
-
84872527628
-
mTOR is a key modulator of ageing and age-related disease
-
CrossRef Medline
-
Johnson S. C, Rabinovitch PS, Kaeberlein M (2013) mTOR is a key modulator of ageing and age-related disease. Nature 493:338-345. CrossRef Medline
-
(2013)
Nature
, vol.493
, pp. 338-345
-
-
Johnson, S.C.1
Rabinovitch, P.S.2
Kaeberlein, M.3
-
22
-
-
79953317808
-
Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism
-
CrossRef Medline
-
Jordan S. D, Krüger M, Willmes DM, Redemann N, Wunderlich FT, Brönneke HS, Merkwirth C, Kashkar H, Olkkonen VM, Böttger T, Braun T, Seibler J, Brüning JC (2011) Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism. Nat Cell Biol 13:434-446. CrossRef Medline
-
(2011)
Nat Cell Biol
, vol.13
, pp. 434-446
-
-
Jordan, S.D.1
Krüger, M.2
Willmes, D.M.3
Redemann, N.4
Wunderlich, F.T.5
Brönneke, H.S.6
Merkwirth, C.7
Kashkar, H.8
Olkkonen, V.M.9
Böttger, T.10
Braun, T.11
Seibler, J.12
Brüning, J.C.13
-
23
-
-
38549126643
-
KEGG for linking genomes to life and the environment
-
Medline
-
Kanehisa M., Araki M, Goto S, Hattori M, Hirakawa M, Itoh M, Katayama T, Kawashima S., Okuda S, Tokimatsu T, Yamanishi Y (2008) KEGG for linking genomes to life and the environment. Nucleic Acids Res 36:D480-D484. Medline
-
(2008)
Nucleic Acids Res
, vol.36
-
-
Kanehisa, M.1
Araki, M.2
Goto, S.3
Hattori, M.4
Hirakawa, M.5
Itoh, M.6
Katayama, T.7
Kawashima, S.8
Okuda, S.9
Tokimatsu, T.10
Yamanishi, Y.11
-
24
-
-
0033534701
-
Inducible site-specific recombination in the brain
-
CrossRef Medline
-
Kellendonk C., Tronche F, Casanova E, Anlag K, Opherk C, Schütz G (1999) Inducible site-specific recombination in the brain. J Mol Biol 285:175-182. CrossRef Medline
-
(1999)
J Mol Biol
, vol.285
, pp. 175-182
-
-
Kellendonk, C.1
Tronche, F.2
Casanova, E.3
Anlag, K.4
Opherk, C.5
Schütz, G.6
-
25
-
-
80054977111
-
PI3Kgamma is required for NMDA receptor-dependent long-term depression and behavioral flexibility
-
CrossRef Medline
-
Kim J. I, Lee HR, Sim SE, Baek J, Yu NK, Choi JH, Ko HG, Lee YS, Park SW, Kwak C., Ahn SJ, Choi SY, Kim H, Kim KH, Backx PH, Bradley CA, Kim E, Jang DJ, Lee K, Kim SJ, et al. (2011) PI3Kgamma is required for NMDA receptor-dependent long-term depression and behavioral flexibility. Nat Neurosci 14:1447-1454. CrossRef Medline
-
(2011)
Nat Neurosci
, vol.14
, pp. 1447-1454
-
-
Kim, J.I.1
Lee, H.R.2
Sim, S.E.3
Baek, J.4
Yu, N.K.5
Choi, J.H.6
Ko, H.G.7
Lee, Y.S.8
Park, S.W.9
Kwak, C.10
Ahn, S.J.11
Choi, S.Y.12
Kim, H.13
Kim, K.H.14
Backx, P.H.15
Bradley, C.A.16
Kim, E.17
Jang, D.J.18
Lee, K.19
Kim, S.J.20
more..
-
26
-
-
84856731262
-
Evoked axonal oxytocin release in the central amygdala attenuates fear response
-
CrossRef Medline
-
Knobloch H. S, Charlet A, Hoffmann LC, Eliava M, Khrulev S, Cetin AH, Osten P., Schwarz MK, Seeburg PH, Stoop R, Grinevich V (2012) Evoked axonal oxytocin release in the central amygdala attenuates fear response. Neuron 73:553-566. CrossRef Medline
-
(2012)
Neuron
, vol.73
, pp. 553-566
-
-
Knobloch, H.S.1
Charlet, A.2
Hoffmann, L.C.3
Eliava, M.4
Khrulev, S.5
Cetin, A.H.6
Osten, P.7
Schwarz, M.K.8
Seeburg, P.H.9
Stoop, R.10
Grinevich, V.11
-
27
-
-
78049520499
-
MicroRNA loss enhances learning and memory in mice
-
CrossRef Medline
-
Konopka W., Kiryk A, Novak M, Herwerth M, Parkitna JR, Wawrzyniak M, Kowarsch A., Michaluk P, Dzwonek J, Arnsperger T, Wilczynski G, Merkenschlager M., Theis FJ, Köhr G, Kaczmarek L, Schütz G (2010) MicroRNA loss enhances learning and memory in mice. J Neurosci 30: 14835-14842. CrossRef Medline
-
(2010)
J Neurosci
, vol.30
, pp. 14835-14842
-
-
Konopka, W.1
Kiryk, A.2
Novak, M.3
Herwerth, M.4
Parkitna, J.R.5
Wawrzyniak, M.6
Kowarsch, A.7
Michaluk, P.8
Dzwonek, J.9
Arnsperger, T.10
Wilczynski, G.11
Merkenschlager, M.12
Theis, F.J.13
Köhr, G.14
Kaczmarek, L.15
Schütz, G.16
-
28
-
-
84874715061
-
Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b
-
CrossRef Medline
-
Kornfeld J. W, Baitzel C, Könner AC, Nicholls HT, Vogt MC, Herrmanns K, Scheja L., Haumaitre C, Wolf AM, Knippschild U, Seibler J, Cereghini S, Heeren J., Stoffel M, Brüning JC (2013) Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b. Nature 494:111-115. CrossRef Medline
-
(2013)
Nature
, vol.494
, pp. 111-115
-
-
Kornfeld, J.W.1
Baitzel, C.2
Könner, A.C.3
Nicholls, H.T.4
Vogt, M.C.5
Herrmanns, K.6
Scheja, L.7
Haumaitre, C.8
Wolf, A.M.9
Knippschild, U.10
Seibler, J.11
Cereghini, S.12
Heeren, J.13
Stoffel, M.14
Brüning, J.C.15
-
29
-
-
79955010799
-
miTALOS: Analyzing the tissue-specific regulation of signaling pathways by human and mouse microRNAs
-
CrossRef Medline
-
Kowarsch A., Preusse M, Marr C, Theis FJ (2011) miTALOS: analyzing the tissue-specific regulation of signaling pathways by human and mouse microRNAs. Rna 17:809-819. CrossRef Medline
-
(2011)
Rna
, vol.17
, pp. 809-819
-
-
Kowarsch, A.1
Preusse, M.2
Marr, C.3
Theis, F.J.4
-
30
-
-
84885400581
-
A neuroprotective phase precedes striatal degeneration upon nucleolar stress
-
CrossRef Medline
-
Kreiner G., Bierhoff H, Armentano M, Rodriguez-Parkitna J, Sowodniok K, Naranjo J. R, Bonfanti L, Liss B, Schütz G, Grummt I, Parlato R (2013) A neuroprotective phase precedes striatal degeneration upon nucleolar stress. Cell Death Differ 20:1455-1464. CrossRef Medline
-
(2013)
Cell Death Differ
, vol.20
, pp. 1455-1464
-
-
Kreiner, G.1
Bierhoff, H.2
Armentano, M.3
Rodriguez-Parkitna, J.4
Sowodniok, K.5
Naranjo, J.R.6
Bonfanti, L.7
Liss, B.8
Schütz, G.9
Grummt, I.10
Parlato, R.11
-
31
-
-
84859778293
-
mTOR signaling in growth control and disease
-
CrossRef Medline
-
Laplante M., Sabatini DM (2012) mTOR signaling in growth control and disease. Cell 149:274-293. CrossRef Medline
-
(2012)
Cell
, vol.149
, pp. 274-293
-
-
Laplante, M.1
Sabatini, D.M.2
-
32
-
-
0036195102
-
Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene
-
CrossRef Medline
-
Lesche R., Groszer M, Gao J, Wang Y, Messing A, Sun H, Liu X, Wu H (2002) Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene. Genesis 32:148-149. CrossRef Medline
-
(2002)
Genesis
, vol.32
, pp. 148-149
-
-
Lesche, R.1
Groszer, M.2
Gao, J.3
Wang, Y.4
Messing, A.5
Sun, H.6
Liu, X.7
Wu, H.8
-
33
-
-
73949140059
-
A robust and high-throughput Cre reporting and characterization system for the whole mouse brain
-
CrossRef Medline
-
Madisen L., Zwingman TA, Sunkin SM, Oh SW, Zariwala HA, Gu H, Ng LL, Palmiter R. D, Hawrylycz MJ, Jones AR, Lein ES, Zeng H (2010) A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. Nat Neurosci 13:133-140. CrossRef Medline
-
(2010)
Nat Neurosci
, vol.13
, pp. 133-140
-
-
Madisen, L.1
Zwingman, T.A.2
Sunkin, S.M.3
Oh, S.W.4
Zariwala, H.A.5
Gu, H.6
Ng, L.L.7
Palmiter, R.D.8
Hawrylycz, M.J.9
Jones, A.R.10
Lein, E.S.11
Zeng, H.12
-
34
-
-
8444224619
-
Balancing Akt with S6K: Implications for both metabolic diseases and tumorigenesis
-
CrossRef Medline
-
Manning B. D (2004) Balancing Akt with S6K: implications for both metabolic diseases and tumorigenesis. J Cell Biol 167:399-403. CrossRef Medline
-
(2004)
J Cell Biol
, vol.167
, pp. 399-403
-
-
Manning, B.D.1
-
35
-
-
77952828883
-
RNA localization in neurite morphogenesis and synaptic regulation: Current evidence and novel approaches
-
CrossRef Medline
-
Mikl M., Vendra G, Doyle M, Kiebler MA (2010) RNA localization in neurite morphogenesis and synaptic regulation: current evidence and novel approaches. J Comp Physiol A Neuroethol Sens Neural Behav Physiol 196: 321-334. CrossRef Medline
-
(2010)
J Comp Physiol A Neuroethol Sens Neural Behav Physiol
, vol.196
, pp. 321-334
-
-
Mikl, M.1
Vendra, G.2
Doyle, M.3
Kiebler, M.A.4
-
36
-
-
34147180058
-
Evaluation of locked nucleic acid-modified small interfering RNA in vitro and in vivo
-
CrossRef Medline
-
Mook O. R, Baas F, de Wissel MB, Fluiter K (2007) Evaluation of locked nucleic acid-modified small interfering RNA in vitro and in vivo. Mol Cancer Ther 6:833-843. CrossRef Medline
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 833-843
-
-
Mook, O.R.1
Baas, F.2
de Wissel, M.B.3
Fluiter, K.4
-
37
-
-
63449109316
-
Critical role for hypothalamic mTOR activity in energy balance
-
CrossRef Medline
-
Mori H., Inoki K, Münzberg H, Opland D, Faouzi M, Villanueva EC, Ikenoue T, Kwiatkowski D, MacDougald OA, Myers MG Jr, Guan KL (2009) Critical role for hypothalamic mTOR activity in energy balance. Cell Metab 9:362-374. CrossRef Medline
-
(2009)
Cell Metab
, vol.9
, pp. 362-374
-
-
Mori, H.1
Inoki, K.2
Münzberg, H.3
Opland, D.4
Faouzi, M.5
Villanueva, E.C.6
Ikenoue, T.7
Kwiatkowski, D.8
McDougald, O.A.9
Myers Jr., M.G.10
Guan, K.L.11
-
38
-
-
84865797929
-
Role of microRNA processing in adipose tissue in stress defense and longevity
-
CrossRef Medline
-
Mori M. A, Raghavan P, Thomou T, Boucher J, Robida-Stubbs S, Macotela Y, Russell S. J, Kirkland JL, Blackwell TK, Kahn CR (2012) Role of microRNA processing in adipose tissue in stress defense and longevity. Cell Metab 16:336-347. CrossRef Medline
-
(2012)
Cell Metab
, vol.16
, pp. 336-347
-
-
Mori, M.A.1
Raghavan, P.2
Thomou, T.3
Boucher, J.4
Robida-Stubbs, S.5
McOtela, Y.6
Russell, S.J.7
Kirkland, J.L.8
Blackwell, T.K.9
Kahn, C.R.10
-
39
-
-
58749086043
-
The geometry of leptin action in the brain: More complicated than a simple ARC
-
CrossRef Medline
-
Myers M. G Jr, Münzberg H, Leinninger GM, Leshan RL (2009) The geometry of leptin action in the brain: more complicated than a simple ARC. Cell Metab 9:117-123. CrossRef Medline
-
(2009)
Cell Metab
, vol.9
, pp. 117-123
-
-
Myers Jr., M.G.1
Münzberg, H.2
Leinninger, G.M.3
Leshan, R.L.4
-
40
-
-
77749254828
-
Caveolin gene transfer improves glucose metabolism in diabetic mice
-
CrossRef Medline
-
Otsu K., Toya Y, Oshikawa J, Kurotani R, Yazawa T, Sato M, Yokoyama U, Umemura S., Minamisawa S, Okumura S, Ishikawa Y (2010) Caveolin gene transfer improves glucose metabolism in diabetic mice. Am J Physiol Cell Physiol 298:C450-C456. CrossRef Medline
-
(2010)
Am J Physiol Cell Physiol
, vol.298
-
-
Otsu, K.1
Toya, Y.2
Oshikawa, J.3
Kurotani, R.4
Yazawa, T.5
Sato, M.6
Yokoyama, U.7
Umemura, S.8
Minamisawa, S.9
Okumura, S.10
Ishikawa, Y.11
-
42
-
-
33745819212
-
Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity
-
CrossRef Medline
-
Plum L., Ma X, Hampel B, Balthasar N, Coppari R, Münzberg H, Shanabrough M, Burdakov D, Rother E, Janoschek R, Alber J, Belgardt BF, Koch L, Seibler J, Schwenk F, Fekete C, Suzuki A, Mak TW, Krone W, Horvath TL, et al. (2006) Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity. J Clin Invest 116:1886-1901. CrossRef Medline
-
(2006)
J Clin Invest
, vol.116
, pp. 1886-1901
-
-
Plum, L.1
Ma, X.2
Hampel, B.3
Balthasar, N.4
Coppari, R.5
Münzberg, H.6
Shanabrough, M.7
Burdakov, D.8
Rother, E.9
Janoschek, R.10
Alber, J.11
Belgardt, B.F.12
Koch, L.13
Seibler, J.14
Schwenk, F.15
Fekete, C.16
Suzuki, A.17
Mak, T.W.18
Krone, W.19
Horvath, T.L.20
more..
-
43
-
-
0035924078
-
Chronic administration of neuropeptide Y into the lateral ventricle of C57BL/6J male mice produces an obesity syndrome including hyperphagia, hyperleptinemia, insulin resistance, and hypogonadism
-
CrossRef Medline
-
Raposinho P. D, Pierroz DD, Broqua P, White RB, Pedrazzini T, Aubert ML (2001) Chronic administration of neuropeptide Y into the lateral ventricle of C57BL/6J male mice produces an obesity syndrome including hyperphagia, hyperleptinemia, insulin resistance, and hypogonadism. Mol Cell Endocrinol 185:195-204. CrossRef Medline
-
(2001)
Mol Cell Endocrinol
, vol.185
, pp. 195-204
-
-
Raposinho, P.D.1
Pierroz, D.D.2
Broqua, P.3
White, R.B.4
Pedrazzini, T.5
Aubert, M.L.6
-
44
-
-
84856961540
-
Central nervous system mechanisms linking the consumption of palatable high-fat diets to the defense of greater adiposity
-
CrossRef Medline
-
Ryan K. K, Woods SC, Seeley RJ (2012) Central nervous system mechanisms linking the consumption of palatable high-fat diets to the defense of greater adiposity. Cell Metab 15:137-149. CrossRef Medline
-
(2012)
Cell Metab
, vol.15
, pp. 137-149
-
-
Ryan, K.K.1
Woods, S.C.2
Seeley, R.J.3
-
45
-
-
84877659963
-
Deletion of miRNA processing enzyme Dicer in POMC-expressing cells leads to pituitary dysfunction, neurodegeneration and development of obesity
-
CrossRef Medline
-
Schneeberger M., Altirriba J, García A, Esteban Y, Castaño C, García-Lavandeira M, Alvarez CV, Gomis R, Claret M (2012) Deletion of miRNA processing enzyme Dicer in POMC-expressing cells leads to pituitary dysfunction, neurodegeneration and development of obesity. Mol Metab 2:74-85. CrossRef Medline
-
(2012)
Mol Metab
, vol.2
, pp. 74-85
-
-
Schneeberger, M.1
Altirriba, J.2
García, A.3
Esteban, Y.4
Castaño, C.5
García-Lavandeira, M.6
Alvarez, C.V.7
Gomis, R.8
Claret, M.9
-
46
-
-
70450248489
-
MicroRNAs at the synapse
-
CrossRef Medline
-
Schratt G. (2009) MicroRNAs at the synapse. Nat Rev Neurosci 10:842-849. CrossRef Medline
-
(2009)
Nat Rev Neurosci
, vol.10
, pp. 842-849
-
-
Schratt, G.1
-
47
-
-
0029739970
-
Identification of targets of leptin action in rat hypothalamus
-
CrossRef Medline
-
Schwartz M. W, Seeley RJ, Campfield LA, Burn P, Baskin DG (1996) Identification of targets of leptin action in rat hypothalamus. J Clin Invest 98:1101-1106. CrossRef Medline
-
(1996)
J Clin Invest
, vol.98
, pp. 1101-1106
-
-
Schwartz, M.W.1
Seeley, R.J.2
Campfield, L.A.3
Burn, P.4
Baskin, D.G.5
-
48
-
-
0242363255
-
Monitoring of stored and available fuel by the CNS: Implications for obesity
-
CrossRef Medline
-
Seeley R. J, Woods SC (2003) Monitoring of stored and available fuel by the CNS: implications for obesity. Nat Rev Neurosci 4:901-909. CrossRef Medline
-
(2003)
Nat Rev Neurosci
, vol.4
, pp. 901-909
-
-
Seeley, R.J.1
Woods, S.C.2
-
49
-
-
33750318273
-
A guide through present computational approaches for the identification of mammalian microRNA targets
-
CrossRef Medline
-
Sethupathy P., Megraw M, Hatzigeorgiou AG (2006) A guide through present computational approaches for the identification of mammalian microRNA targets. Nat Methods 3:881-886. CrossRef Medline
-
(2006)
Nat Methods
, vol.3
, pp. 881-886
-
-
Sethupathy, P.1
Megraw, M.2
Hatzigeorgiou, A.G.3
-
50
-
-
84874689138
-
Elevated RalA activity in the hippocampus of PI3Kgamma knock-out mice lacking NMDAR-dependent long-term depression
-
CrossRef Medline
-
Sim S. E, Lee HR, Kim JI, Choi SL, Bakes J, Jang DJ, Lee K, Han K, Kim E, Kaang BK (2013) Elevated RalA activity in the hippocampus of PI3Kgamma knock-out mice lacking NMDAR-dependent long-term depression. BMB Rep 46:103-106. CrossRef Medline
-
(2013)
BMB Rep
, vol.46
, pp. 103-106
-
-
Sim, S.E.1
Lee, H.R.2
Kim, J.I.3
Choi, S.L.4
Bakes, J.5
Jang, D.J.6
Lee, K.7
Han, K.8
Kim, E.9
Kaang, B.K.10
-
51
-
-
0032923739
-
Generalized lacZ expression with the ROSA26 Cre reporter strain
-
CrossRef Medline
-
Soriano P. (1999) Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 21:70-71. CrossRef Medline
-
(1999)
Nat Genet
, vol.21
, pp. 70-71
-
-
Soriano, P.1
-
52
-
-
79960672953
-
Moderate long-term modulation of neuropeptide Y in hypothalamic arcuate nucleus induces energy balance alterations in adult rats
-
CrossRef Medline
-
Sousa-Ferreira L., Garrido M, Nascimento-Ferreira I, Nobrega C, Santos-Carvalho A, Alvaro AR, Rosmaninho-Salgado J, Kaster M, Kügler S, de Almeida L. P, Cavadas C (2011) Moderate long-term modulation of neuropeptide Y in hypothalamic arcuate nucleus induces energy balance alterations in adult rats. PLoS One 6:e22333. CrossRef Medline
-
(2011)
PLoS One
, vol.6
-
-
Sousa-Ferreira, L.1
Garrido, M.2
Nascimento-Ferreira, I.3
Nobrega, C.4
Santos-Carvalho, A.5
Alvaro, A.R.6
Rosmaninho-Salgado, J.7
Kaster, M.8
Kügler, S.9
de Almeida, L.P.10
Cavadas, C.11
-
53
-
-
0029090212
-
Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase
-
CrossRef Medline
-
Stoyanov B., Volinia S, Hanck T, Rubio I, Loubtchenkov M, Malek D, Stoyanova S, Vanhaesebroeck B, Dhand R, Nürnberg B (1995) Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase. Science 269:690-693. CrossRef Medline
-
(1995)
Science
, vol.269
, pp. 690-693
-
-
Stoyanov, B.1
Volinia, S.2
Hanck, T.3
Rubio, I.4
Loubtchenkov, M.5
Malek, D.6
Stoyanova, S.7
Vanhaesebroeck, B.8
Dhand, R.9
Nürnberg, B.10
-
54
-
-
79959845414
-
MicroRNAs 103 and 107 regulate insulin sensitivity
-
CrossRef Medline
-
Trajkovski M., Hausser J, Soutschek J, Bhat B, Akin A, Zavolan M, Heim MH, Stoffel M. (2011) MicroRNAs 103 and 107 regulate insulin sensitivity. Nature 474:649-653. CrossRef Medline
-
(2011)
Nature
, vol.474
, pp. 649-653
-
-
Trajkovski, M.1
Hausser, J.2
Soutschek, J.3
Bhat, B.4
Akin, A.5
Zavolan, M.6
Heim, M.H.7
Stoffel, M.8
-
55
-
-
70349315117
-
Complex regulation of mammalian target of rapamycin complex 1 in the basomedial hypothalamus by leptin and nutritional status
-
CrossRef Medline
-
Villanueva E. C, Münzberg H, Cota D, Leshan RL, Kopp K, Ishida-Takahashi R, Jones JC, Fingar DC, Seeley RJ, Myers MG Jr (2009) Complex regulation of mammalian target of rapamycin complex 1 in the basomedial hypothalamus by leptin and nutritional status. Endocrinology 150:4541-4551. CrossRef Medline
-
(2009)
Endocrinology
, vol.150
, pp. 4541-4551
-
-
Villanueva, E.C.1
Münzberg, H.2
Cota, D.3
Leshan, R.L.4
Kopp, K.5
Ishida-Takahashi, R.6
Jones, J.C.7
Fingar, D.C.8
Seeley, R.J.9
Myers Jr., M.G.10
-
56
-
-
79951999061
-
GABAergic signaling by AgRP neurons prevents anorexia via a melanocortin-independent mechanism
-
CrossRef Medline
-
Wu Q., Palmiter RD (2011) GABAergic signaling by AgRP neurons prevents anorexia via a melanocortin-independent mechanism. Eur J Pharmacol 660:21-27. CrossRef Medline
-
(2011)
Eur J Pharmacol
, vol.660
, pp. 21-27
-
-
Wu, Q.1
Palmiter, R.D.2
-
57
-
-
84859215897
-
Deciphering a neuronal circuit that mediates appetite
-
CrossRef Medline
-
Wu Q., Clark MS, Palmiter RD (2012) Deciphering a neuronal circuit that mediates appetite. Nature 483:594-597. CrossRef Medline
-
(2012)
Nature
, vol.483
, pp. 594-597
-
-
Wu, Q.1
Clark, M.S.2
Palmiter, R.D.3
-
58
-
-
84255199265
-
Central nervous control of energy and glucose balance: Focus on the central melanocortin system
-
CrossRef Medline
-
Xu Y., Elmquist JK, Fukuda M (2011) Central nervous control of energy and glucose balance: focus on the central melanocortin system. Ann N Y Acad Sci 1243:1-14. CrossRef Medline
-
(2011)
Ann N Y Acad Sci
, vol.1243
, pp. 1-14
-
-
Xu, Y.1
Elmquist, J.K.2
Fukuda, M.3
-
59
-
-
84864927001
-
Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons
-
CrossRef Medline
-
Yang S. B, Tien AC, Boddupalli G, Xu AW, Jan YN, Jan LY (2012) Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons. Neuron 75:425-436. CrossRef Medline
-
(2012)
Neuron
, vol.75
, pp. 425-436
-
-
Yang, S.B.1
Tien, A.C.2
Boddupalli, G.3
Xu, A.W.4
Jan, Y.N.5
Jan, L.Y.6
-
60
-
-
78650510609
-
mTOR: From growth signal integration to cancer, diabetes and ageing
-
CrossRef Medline
-
Zoncu R., Efeyan A, Sabatini DM (2011) mTOR: from growth signal integration to cancer, diabetes and ageing. Nat Rev Mol Cell Biol 12:21-35. CrossRef Medline
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, pp. 21-35
-
-
Zoncu, R.1
Efeyan, A.2
Sabatini, D.M.3
-
61
-
-
80054935981
-
MicroRNA-34c is a novel target to treat dementias
-
CrossRef Medline
-
Zovoilis A., Agbemenyah HY, Agis-Balboa RC, Stilling RM, Edbauer D, Rao P, Farinelli L., Delalle I, Schmitt A, Falkai P, Bahari-Javan S, Burkhardt S, Sananbenesi F., Fischer A (2011) MicroRNA-34c is a novel target to treat dementias. EMBO J 30:4299-4308. CrossRef Medline
-
(2011)
EMBO J
, vol.30
, pp. 4299-4308
-
-
Zovoilis, A.1
Agbemenyah, H.Y.2
Agis-Balboa, R.C.3
Stilling, R.M.4
Edbauer, D.5
Rao, P.6
Farinelli, L.7
Delalle, I.8
Schmitt, A.9
Falkai, P.10
Bahari-Javan, S.11
Burkhardt, S.12
Sananbenesi, F.13
Fischer, A.14
|