AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and Survival

Cell Metabolism

Volumn 23, Issue 4, 2016, Pages 649-662

  Kishton, Rigel J ^a   Barnes, Carson E ^a   Nichols, Amanda G ^a   Cohen, Sivan ^a   Gerriets, Valerie A ^a   Siska, Peter J ^a,b   Macintyre, Andrew N ^a   Goraksha Hicks, Pankuri ^a   De Cubas, Aguirre A ^c   Liu, Tingyu ^a   Warmoes, Marc O ^d   Abel, E Dale ^e   Yeoh, Allen Eng Juh ^f,g   Gershon, Timothy R ^h   Rathmell, W Kimryn ^c   Richards, Kristy L ^h   Locasale, Jason W ^a,d   Rathmell, Jeffrey C ^a,b  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c VANDERBILT INGRAM CANCER CENTER   (United States)

^d University of Iowa ^*  (United States)

^e UNIVERSITY OF IOWA   (United States)

^f NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^g NATIONAL UNIVERSITY HEALTH SYSTEM   (Singapore)

^h UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE KINASE; GLUCOSE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PHENFORMIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); TAMOXIFEN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; NOTCH RECEPTOR; TARGET OF RAPAMYCIN KINASE;

ACUTE LYMPHOBLASTIC LEUKEMIA; AEROBIC METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; CELL STRESS; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; GLYCOLYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPHOCYTE PROLIFERATION; METABOLIC STRESS; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; ANIMAL; C57BL MOUSE; METABOLISM; MITOCHONDRION; PATHOLOGY; PHYSIOLOGICAL STRESS; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CELL LINE, TUMOR; CELL SURVIVAL; GLYCOLYSIS; HUMANS; MICE, INBRED C57BL; MITOCHONDRIA; MULTIPROTEIN COMPLEXES; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; T-LYMPHOCYTES; TOR SERINE-THREONINE KINASES;

EID: 84963704497     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2016.03.008     Document Type: Article

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