Sphingomyelin and sphingomyelin synthase (SMS) in the malignant transformation of glioma cells and in 2-hydroxyoleic acid therapy

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 49, 2011, Pages 19569-19574

  Barceló Coblijn, Gwendolyn ^a   Martin, Maria Laura ^a   De Almeida, Rodrigo F M ^b   Noguera Salvà, Maria Antònia ^a   Marcilla Etxenike, Amaia ^a   Guardiola Serrano, Francisca ^a   Lüth, Anja ^c   Kleuser, Burhard ^c   Halver, John E ^d   Escribá, Pablo V ^a  

^a UNIVERSITAT DE LES ILLES BALEARS   (Spain)

^b UNIVERSITY OF LISBON   (Portugal)

^c UNIVERSITY OF POTSDAM   (Germany)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Anticancer; Lung cancer; Membrane lipids; Membrane lipid therapy

Indexed keywords

DIHYDROFOLATE REDUCTASE; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLSERINE; RICINOLEIC ACID; SPHINGOMYELIN; SPHINGOMYELIN SYNTHASE; SYNTHETASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL MEMBRANE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; FIBROBLAST; GLIOMA CELL; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LUNG NON SMALL CELL CANCER; MALIGNANT TRANSFORMATION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; STRUCTURE ACTIVITY RELATION;

ANTIGENS, CD95; APOPTOSIS; BRIDGED COMPOUNDS; CELL CYCLE CHECKPOINTS; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL MEMBRANE; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; CELLS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLIOMA; HUMANS; IMMUNOBLOTTING; JURKAT CELLS; MEMBRANE MICRODOMAINS; MEMBRANE PROTEINS; NERVE TISSUE PROTEINS; OLEIC ACIDS; PHOSPHODIESTERASE INHIBITORS; RAS PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPHINGOMYELINS; THIONES; TRANSFERASES (OTHER SUBSTITUTED PHOSPHATE GROUPS);

EID: 83755172971     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1115484108     Document Type: Article

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