The recycling endosome of Madin-Darby canine kidney cells is a mildly acidic compartment rich in raft components

Molecular Biology of the Cell

Volumn 11, Issue 8, 2000, Pages 2775-2791

  Gagescu, R ^a   Demaurex, N ^a   Parton, R G ^a   Hunziker, W ^a   Huber, L A ^a   Gruenberg, J ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACID; ADENOSINE TRIPHOSPHATASE; CAVEOLIN; CELL PROTEIN; CHOLESTEROL; FLOTILLIN 1; ISOPROTEIN; SPHINGOMYELIN; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL COMPARTMENTALIZATION; ENDOSOME; LIPID COMPOSITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN LOCALIZATION;

EID: 0033836520     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.11.8.2775     Document Type: Article

References (120)

1. Plasma membrane microdomains act as concentration platforms to facilitate intoxication by aerolysin
2. ADP-ribosylation factor 6 and endocytosis at the apical surface of Madin-Darby canine kidney cells
3. An endosomal beta COP is involved in the pH-dependent formation of transport vesicles destined for late endosomes
4. The calmodulin antagonist, W-13, alters transcytosis, recycling, and the morphology of the endocytic pathway in Madin-Darby canine kidney cells
5. Receptor-mediated transcytosis of IgA in MDCK cells is via apical recycling endosomes
6. Basolateral to apical transcytosis in polarized cells is indirect and involves BFA and trimeric G protein sensitive passage through the apical endosome
7. N-Glycans mediate the apical sorting of a GPI-anchored, raft-associated protein in Madin-Darby canine kidney cells
8. Exocytosis of pinocytosed fluid in cultured cells: Kinetic evidence for rapid turnover and compartmentation
9. Flotillin and epidermal surface antigen define a new family of caveolae- associated integral membrane proteins
10. Lysosomal targeting of P-selectin is mediated by a novel sequence within its cytoplasmic tail
11. Microtubule- and motor-dependent fusion in vitro between apical and basolateral endocytic vesicles from MDCK cells
12. Endocytosis in filter-grown Madin-Darby canine kidney cells
13. Functions of lipid rafts in biological membranes
14. The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway
15. Cytoskeletal control of centrioles movement during the establishment of polarity in Madin-Darby canine kidney cells
16. +-ATPase in living cells
17. Association of Rab25 and Rab11a with the apical recycling system of polarized Madin-Darby canine kidney cells
18. Intracellular distribution of Arf proteins in mammalian cells: Arf6 is uniquely localized to the plasma membrane
19. Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments
20. The Rab5 effector EEA1 is a core component of endosome docking
21. Vacuolar ATPase activity is required for endosomal carrier vesicle formation
22. Mechanism of acidification of the trans-Golgi network (TGN): In situ measurements of pH using retrieval of TGN38 and furin from the cell surface
23. A role for POR1, a Rac1-interacting protein, in ARF6-mediated cytoskeletal rearrangements
24. A regulatory role for ARF6 in receptor-mediated endocytosis
25. ARF6 targets recycling vesicles to the plasma membrane: Insights from an ultrastructural investigation
26. Iterative fractionation of recycling receptors from lysosomally destined ligands in an early sorting endosome
27. Caveolae and sorting in the trans-Golgi network of epithelial cells
28. Annexin II is a major component of fusogenic endosomal vesicles
29. +)-ATPase by disulfide bond formation between cysteine 254 and cysteine 532 in subunit
30. Rab 7: An important regulator of late endocytic membrane traffic
31. Identification of syntenin as a protein of the apical early endocytic compartment in Madin-Darby canine kidney cells
32. Compartmentalized activation of the high affinity immunoglobulin E receptor within membrane domains
33. EFA6, a sec7 domain-containing exchange factor for ARF6, coordinates membrane recycling and actin cytoskeleton organization
34. +-ATPase in regulating ATP-dependent endosome acidification
35. Transferrin receptor polarity and recycling accuracy in 'tight' and 'leaky' strains of Madin-Darby canine kidney cells
36. Tetanus toxin-mediated cleavage of cellubrevin impairs exocytosis of transferrin receptor-containing vesicles in CHO cells
37. Intracellular site of asialoglycoprotein receptor-ligand uncoupling: Double-label immunoelectron microscopy during receptor-mediated endocytosis
38. Sorting mechanisms regulating membrane protein traffic in the apical transcytotic pathway of polarized M.D.C.K. cells
39. Rab5 controls early endosome fusion in vitro
40. Two distinct effectors of the small GTPase Rab5 cooperate in endocytic membrane fusion
41. The cytoplasmic domain of P-selectin contains a sorting determinant that mediates rapid degradation in lysosomes
42. Annexins in membrane traffic
43. Characterization of the early endosome and putative endocytic carrier vesicles in vivo and with an assay of vesicle fusion in vitro
44. Membrane transport in the endocytic pathway
45. Functional dissection of COP-I subunits in the biogenesis of multivesicular endosomes
46. ARF1 regulates pH-dependent COP functions in the early endocytic pathway
47. Carbohydrate-mediated Golgi to cell surface transport and apical targeting of membrane proteins
48. Transcytosis of immunoglobulin A in the mouse enterocyte occurs through glycolipid raft- and rab17-containing compartments
49. The subcellular distribution of early endosomes is affected by the annexin II2p11(2) complex
50. Specific release of membrane-bound annexin II and cortical cytoskeletal elements by sequestration of membrane cholesterol
51. Lipid domain structure of the plasma membrane revealed by patching of membrane components
52. Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes
53. Both calmodulin and the unconventional myosin myr4 regulate membrane trafficking along the recycling pathway of MDCK cells
54. Endocytic pathways in polarized Caco-2 cells: Identification of an endosomal compartment accessible from both apical and basolateral surfaces
55. Rab17 localizes to recycling endosomes and regulates receptor-mediated transcytosis in epithelial cells
56. Analysis of the role of p200-containing vesicles in post-Golgi traffic
57. Role of the human transferrin receptor cytoplasmic domain in endocytosis: Localization of a specific signal sequence for internalization
58. +)-ATPase in vivo
59. Adaptors for clathrin-mediated traffic
60. Late endosomal membranes rich in lysobisphosphatidic acid regulate cholesterol transport
61. Lipids, lipid domains and lipid-protein interactions in endocytic membrane traffic
62. A lipid associated with the antiphospholipid syndrome regulates endosome structure and function
63. Membrane microdomains and caveolae
64. Annexin XIIIb associates with lipid microdomains to function in apical delivery
65. Raft association of SNAP receptors acting in apical trafficking in Madin-Darby canine kidney cells
66. SNAP-23 requirement for transferrin recycling in streptolysin-O-permeabilized Madin-Darby canine kidney cells
67. Modulation of endocytic traffic in polarized Madin-Darby canine kidney cells by the small GTPase rhoA
68. Membrane raft microdomains mediate front-rear polarity in migrating cells
69. Oligomerized transferrin receptors are selectively retained by a lumenal sorting signal in a long-lived endocytic recycling compartment
70. Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process
71. Cholesterol-dependent retention of GPI-anchored proteins in endosomes
72. Cellubrevin is a ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion protein
73. Regulation of protein traffic in polarized epithelial cells
74. E.E.A1, an early endosome-associated protein: E.E.A1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine 'fingers' and contains a calmodulin-binding IQ motif
75. Endosome dynamics regulated by a Rho protein
76. Caveolins, a family of scaffolding proteins for organizing 'preassembled signaling complexes' at the plasma membrane
77. Glycosphingolipids are not essential for formation of detergent- resistant membrane rafts in melanoma cells: Methyl-beta-cyclodextrin does not affect cell surface transport of a GPI-anchored protein
78. A novel fluorescent ceramide analogue for studying membrane traffic in animal cells: Accumulation at the Golgi apparatus results in altered spectral properties of the sphingolipid precursor
79. Endocytosis in polarized cells
80. Caveolae and caveolins
81. Meeting of the apical and basolateral endocytic pathways of the Madin-Darby canine kidney cell in late endosomes
82. Axonal and dendritic endocytic pathways in cultured neurons
83. Preparative two-dimensional gel electrophoresis of membrane proteins
84. Overexpression of wild-type and mutant ARF1 and ARF6: Distinct perturbations of non-overlapping membrane compartments
85. Nef-induced CD4 degradation: A diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes
86. Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling endosomes
87. The End2 mutation in CHO cells slows the exit of transferrin receptors from the recycling compartment but bulk membrane recycling is unaffected
88. ADP-ribosylation factor 6 regulates a novel plasma membrane recycling pathway
89. NSF is required for transport from early to late endosomes
90. Involvement of the transmembrane protein p23 in biosynthetic protein transport
91. N-Glycans as apical sorting signals in epithelial cells
92. Role of GTP hydrolysis in fission of caveolae directly from plasma membranes
93. Role of GTP hydrolysis in fission of caveolae directly from plasma membranes
94. The receptor recycling pathway contains two distinct populations of early endosomes with different sorting functions
95. Functional rafts in cell membranes
96. EEA1 links PI(3)K function to Rab5 regulation of endosome fusion
97. Localization of endogenous ARF6 to sites of cortical actin rearrangement and involvement of ARF6 in cell spreading
98. Endosomal localization of the autoantigen EEA1 is mediated by a zinc-binding FYVE finger
99. Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion
100. +)-ATPase
101. Identification of ZO-1: A high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia
102. Lack of acidification in Mycobacterium phagosomes produced by exclusion of the vesicular proton-ATPase
103. Lack of acidification in Mycobacterium phagosomes produced by exclusion of the vesicular proton-ATPase
104. An alpha-helical signal in the cytosolic domain of the interleukin 2 receptor beta chain mediates sorting towards degradation after endocytosis
105. Tubular early endosomal networks in AtT20 and other cells
106. Biochemical analysis of distinct Rab5- and Rab11-positive endosomes along the transferrin pathway
107. Lectins as chaperones in glycoprotein folding
108. Rab11 regulates recycling through the pericentriolar recycling endosome
109. The small GTP-binding protein rab4 controls an early sorting event on the endocytic pathway
110. The small GTP-binding protein rab4 is associated with early endosomes
111. Lipid polarity and sorting in epithelial cells
112. Sorting of sphingolipids in epithelial (Madin-Darby canine kidney) cells
113. A tubular endosomal fraction from rat liver: Biochemical evidence of receptor sorting by default
114. T lymphocyte costimulation mediated by reorganization of membrane microdomains
115. Flotillins/cavatellins are differentially expressed in cells and tissues and form a hetero-oligomeric complex with caveolins in vivo: Characterization and epitope-mapping of a novel flotillin-1 monoclonal antibody prove
116. Cytoplasmic coat proteins involved in endosome function
117. Acidification of endocytic compartments and the intracellular pathways of ligands and receptors
118. Acidification of morphologically distinct endosomes in mutant and wild-type Chinese hamster ovary cells
119. Segregation of transferrin to a mildly acidic (pH 6.5) para-Golgi compartment in the recycling pathway
120. Identification of a putative effector protein for rab11 that participates in transferrin recycling