메뉴 건너뛰기




Volumn 29, Issue 8, 2015, Pages 803-816

Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming

Author keywords

Alternative splicing; Gcn5; IPSCs; Myc; Reprogramming; SAGA

Indexed keywords

HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE GCN5; MYC PROTEIN; TRANSCRIPTION FACTOR SAGA;

EID: 84927768496     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.255109.114     Document Type: Article
Times cited : (62)

References (87)
  • 1
    • 79954414897 scopus 로고    scopus 로고
    • Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network
    • Ang YS, Tsai SY, Lee DF, Monk J, Su J, Ratnakumar K, Ding J, Ge Y, Darr H, Chang B, et al. 2011. Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network. Cell 145: 183–197.
    • (2011) Cell , vol.145 , pp. 183-197
    • Ang, Y.S.1    Tsai, S.Y.2    Lee, D.F.3    Monk, J.4    Su, J.5    Ratnakumar, K.6    Ding, J.7    Ge, Y.8    Darr, H.9    Chang, B.10
  • 2
    • 84886859638 scopus 로고    scopus 로고
    • Chromatin dynamics during cellular reprogramming
    • Apostolou E, Hochedlinger K. 2013. Chromatin dynamics during cellular reprogramming. Nature 502: 462–471.
    • (2013) Nature , vol.502 , pp. 462-471
    • Apostolou, E.1    Hochedlinger, K.2
  • 3
    • 58049200457 scopus 로고    scopus 로고
    • OCT4 spliced variants are differentially expressed in human pluripotent and nonpluripotent cells
    • Atlasi Y, Mowla SJ, Ziaee SA, Gokhale PJ, Andrews PW. 2008. OCT4 spliced variants are differentially expressed in human pluripotent and nonpluripotent cells. Stem Cells 26: 3068–3074.
    • (2008) Stem Cells , vol.26 , pp. 3068-3074
    • Atlasi, Y.1    Mowla, S.J.2    Ziaee, S.A.3    Gokhale, P.J.4    Rews, P.W.5
  • 4
    • 79960621198 scopus 로고    scopus 로고
    • Sgf29 binds histone H3K4me2/3 and is required forSAGAcomplex recruitment and histone H3 acetylation
    • Bian C, Xu C, Ruan J, Lee KK, Burke TL,Tempel W, Barsyte D, Li J, Wu M, Zhou BO, et al. 2011. Sgf29 binds histone H3K4me2/3 and is required forSAGAcomplex recruitment and histone H3 acetylation. EMBO J 30: 2829–2842.
    • (2011) EMBO J , vol.30 , pp. 2829-2842
    • Bian, C.1    Xu, C.2    Ruan, J.3    Lee, K.K.4    Burke, T.L.5    Tempel, W.6    Barsyte, D.7    Li, J.8    Wu, M.9    Zhou, B.O.10
  • 5
    • 84907159518 scopus 로고    scopus 로고
    • The SAGA coactivator complex acts on the whole transcribed genome and is required for RNA polymerase II transcription
    • Bonnet J,Wang CY, Baptista T, Vincent SD, Hsiao WC, Stierle M, Kao CF, Tora L, Devys D. 2014. The SAGA coactivator complex acts on the whole transcribed genome and is required for RNA polymerase II transcription. Genes Dev 28: 1999–2012.
    • (2014) Genes Dev , vol.28 , pp. 1999-2012
    • Bonnet, J.1    Wang, C.Y.2    Baptista, T.3    Vincent, S.D.4    Hsiao, W.C.5    Stierle, M.6    Kao, C.F.7    Tora, L.8    Devys, D.9
  • 6
    • 0029049102 scopus 로고
    • An activity gel assay detects a single, catalytically active histone acetyltransferase subunit in Tetrahymena macronuclei
    • Brownell JE, Allis CD. 1995. An activity gel assay detects a single, catalytically active histone acetyltransferase subunit in Tetrahymena macronuclei. Proc Natl Acad Sci 92: 6364–6368.
    • (1995) Proc Natl Acad Sci , vol.92 , pp. 6364-6368
    • Brownell, J.E.1    Allis, C.D.2
  • 7
    • 0029984469 scopus 로고    scopus 로고
    • Tetrahymena histone acetyltransferase A: A homolog to yeast Gcn5p linking histone acetylation to gene activation
    • Brownell JE, Zhou J, Ranalli T, Kobayashi R, Edmondson DG, Roth SY, Allis CD. 1996. Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation. Cell 84: 843–851.
    • (1996) Cell , vol.84 , pp. 843-851
    • Brownell, J.E.1    Zhou, J.2    Ranalli, T.3    Kobayashi, R.4    Edmondson, D.G.5    Roth, S.Y.6    Allis, C.D.7
  • 8
    • 34247646897 scopus 로고    scopus 로고
    • Loss of Gcn5 acetyltransferase activity leads to neural tube closure defects and exencephaly in mouse embryos
    • Bu P, Evrard YA, Lozano G, Dent SY. 2007. Loss of Gcn5 acetyltransferase activity leads to neural tube closure defects and exencephaly in mouse embryos. Mol Cell Biol 27: 3405–3416.
    • (2007) Mol Cell Biol , vol.27 , pp. 3405-3416
    • Bu, P.1    Evrard, Y.A.2    Lozano, G.3    Dent, S.Y.4
  • 10
    • 44649117905 scopus 로고    scopus 로고
    • Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
    • Chen X, Xu H, Yuan P, Fang F, Huss M, Vega VB, Wong E, Orlov YL, Zhang W, Jiang J, et al. 2008. Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 133: 1106–1117.
    • (2008) Cell , vol.133 , pp. 1106-1117
    • Chen, X.1    Xu, H.2    Yuan, P.3    Fang, F.4    Huss, M.5    Vega, V.B.6    Wong, E.7    Orlov, Y.L.8    Zhang, W.9    Jiang, J.10
  • 11
    • 82755162926 scopus 로고    scopus 로고
    • Alternative splicing produces Nanog protein variants with different capacities for self-renewal and pluripotency in embryonic stem cells
    • Das S, Jena S, Levasseur DN. 2011. Alternative splicing produces Nanog protein variants with different capacities for self-renewal and pluripotency in embryonic stem cells. J Biol Chem 286: 42690–42703.
    • (2011) J Biol Chem , vol.286 , pp. 42690-42703
    • Das, S.1    Jena, S.2    Levasseur, D.N.3
  • 12
    • 84904987438 scopus 로고    scopus 로고
    • Phases of reprogramming
    • David L, Polo JM. 2014. Phases of reprogramming. Stem Cell Res 12: 754–761.
    • (2014) Stem Cell Res , vol.12 , pp. 754-761
    • David, L.1    Polo, J.M.2
  • 13
    • 84899096353 scopus 로고    scopus 로고
    • The polycomb protein ezh2 impacts on induced pluripotent stem cell generation
    • Ding X,Wang X, Sontag S, Qin J,Wanek P, Lin Q, Zenke M. 2014. The polycomb protein ezh2 impacts on induced pluripotent stem cell generation. Stem Cells Dev 23: 931–940.
    • (2014) Stem Cells Dev , vol.23 , pp. 931-940
    • Ding, X.1    Wang, X.2    Sontag, S.3    Qin, J.4    Wanek, P.5    Lin, Q.6    Zenke, M.7
  • 14
    • 46149110511 scopus 로고    scopus 로고
    • An RNAi screen of chromatin proteins identifies Tip60-p400 as a regulator of embryonic stem cell identity
    • Fazzio TG, Huff JT, Panning B. 2008. An RNAi screen of chromatin proteins identifies Tip60-p400 as a regulator of embryonic stem cell identity. Cell 134: 162–174.
    • (2008) Cell , vol.134 , pp. 162-174
    • Fazzio, T.G.1    Huff, J.T.2    Panning, B.3
  • 16
    • 74549209773 scopus 로고    scopus 로고
    • Hook3 interacts with PCM1 to regulate pericentriolar material assembly and the timing of neurogenesis
    • Ge X, Frank CL, Calderon de Anda F, Tsai LH. 2010. Hook3 interacts with PCM1 to regulate pericentriolar material assembly and the timing of neurogenesis. Neuron 65: 191–203.
    • (2010) Neuron , vol.65 , pp. 191-203
    • Ge, X.1    Frank, C.L.2    Calderon De Anda, F.3    Tsai, L.H.4
  • 17
    • 84870948470 scopus 로고    scopus 로고
    • A late transition in somatic cell reprogramming requires regulators distinct from the pluripotency network
    • Golipour A, David L, Liu Y, Jayakumaran G, Hirsch CL, Trcka D, Wrana JL. 2012. A late transition in somatic cell reprogramming requires regulators distinct from the pluripotency network. Cell Stem Cell 11: 769–782.
    • (2012) Cell Stem Cell , vol.11 , pp. 769-782
    • Golipour, A.1    David, L.2    Liu, Y.3    Jayakumaran, G.4    Hirsch, C.L.5    Trcka, D.6    Wrana, J.L.7
  • 18
    • 0030797349 scopus 로고    scopus 로고
    • Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: Characterization of an Ada complex and the SAGA (Spt/Ada) complex
    • Grant PA, Duggan L, Cote J, Roberts SM, Brownell JE, Candau R, Ohba R, Owen-Hughes T, Allis CD, Winston F, et al. 1997. Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex. Genes Dev 11: 1640–1650.
    • (1997) Genes Dev , vol.11 , pp. 1640-1650
    • Grant, P.A.1    Duggan, L.2    Cote, J.3    Roberts, S.M.4    Brownell, J.E.5    Candau, R.6    Ohba, R.7    Owen-Hughes, T.8    Allis, C.D.9    Winston, F.10
  • 19
    • 31344434715 scopus 로고    scopus 로고
    • Host cell factor and an uncharacterized SANT domain protein are stable components of ATAC, a novel dAda2A/dGcn5-containing histone acetyltransferase complex in Drosophila
    • Guelman S, Suganuma T, Florens L, Swanson SK, Kiesecker CL, Kusch T, Anderson S, Yates JRIII, Washburn MP, Abmayr SM, et al. 2006. Host cell factor and an uncharacterized SANT domain protein are stable components of ATAC, a novel dAda2A/dGcn5-containing histone acetyltransferase complex in Drosophila. Mol Cell Biol 26: 871–882.
    • (2006) Mol Cell Biol , vol.26 , pp. 871-882
    • Guelman, S.1    Suganuma, T.2    Florens, L.3    Swanson, S.K.4    Kiesecker, C.L.5    Kusch, T.6    Erson, S.7    Yates, J.8    Washburn, M.P.9    Abmayr, S.M.10
  • 23
    • 84897989106 scopus 로고    scopus 로고
    • Tet and TDG mediate DNA demethylation essential for mesenchymal-to-epithelial transition in somatic cell reprogramming
    • Hu X, Zhang L, Mao SQ, Li Z, Chen J, Zhang RR, Wu HP, Gao J, Guo F, Liu W, et al. 2014. Tet and TDG mediate DNA demethylation essential for mesenchymal-to-epithelial transition in somatic cell reprogramming. Cell Stem Cell 14: 512–522.
    • (2014) Cell Stem Cell , vol.14 , pp. 512-522
    • Hu, X.1    Zhang, L.2    Mao, S.Q.3    Li, Z.4    Chen, J.5    Zhang, R.R.6    Wu, H.P.7    Gao, J.8    Guo, F.9    Liu, W.10
  • 24
    • 84898608302 scopus 로고    scopus 로고
    • IPS cells: A game changer for future medicine
    • Inoue H, Nagata N, Kurokawa H, Yamanaka S. 2014. iPS cells: a game changer for future medicine. EMBO J 33: 409–417.
    • (2014) EMBO J , vol.33 , pp. 409-417
    • Inoue, H.1    Nagata, N.2    Kurokawa, H.3    Yamanaka, S.4
  • 25
    • 84861961269 scopus 로고    scopus 로고
    • Alternative splicing: Decoding an expansive regulatory layer
    • Irimia M, Blencowe BJ. 2012. Alternative splicing: decoding an expansive regulatory layer. Curr Opin Cell Biol 24: 323–332.
    • (2012) Curr Opin Cell Biol , vol.24 , pp. 323-332
    • Irimia, M.1    Blencowe, B.J.2
  • 26
  • 27
    • 84910131191 scopus 로고    scopus 로고
    • Gcn5 and PCAF negatively regulate interferon-β production through HAT-independent inhibition of TBK1
    • Jin Q, Zhuang L, Lai B, Wang C, Li W, Dolan B, Lu Y, Wang Z, Zhao K, Peng W, et al. 2014b. Gcn5 and PCAF negatively regulate interferon-β production through HAT-independent inhibition of TBK1. EMBO Rep 15: 1192–1201.
    • (2014) EMBO Rep , vol.15 , pp. 1192-1201
    • Jin, Q.1    Zhuang, L.2    Lai, B.3    Wang, C.4    Li, W.5    Dolan, B.6    Lu, Y.7    Wang, Z.8    Zhao, K.9    Peng, W.10
  • 29
    • 64749092881 scopus 로고    scopus 로고
    • Use of in vivo biotinylation to study protein–protein and protein–DNAinteractions in mouse embryonic stem cells
    • Kim J, Cantor AB, Orkin SH,Wang J. 2009. Use of in vivo biotinylation to study protein–protein and protein–DNAinteractions in mouse embryonic stem cells. Nat Protoc 4: 506–517.
    • (2009) Nat Protoc , vol.4 , pp. 506-517
    • Kim, J.1    Cantor, A.B.2    Orkin, S.H.3    Wang, J.4
  • 30
    • 77957757417 scopus 로고    scopus 로고
    • A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs
    • Kim J,Woo AJ, Chu J, Snow JW, Fujiwara Y, Kim CG, Cantor AB, Orkin SH. 2010. A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs. Cell 143: 313–324.
    • (2010) Cell , vol.143 , pp. 313-324
    • Kim, J.1    Woo, A.J.2    Chu, J.3    Snow, J.W.4    Fujiwara, Y.5    Kim, C.G.6    Cantor, A.B.7    Orkin, S.H.8
  • 33
    • 80555156095 scopus 로고    scopus 로고
    • SAGA and ATAC histone acetyl transferase complexes regulate distinct sets of genes and ATAC defines a class of p300-independent enhancers
    • Krebs AR, Karmodiya K, Lindahl-Allen M, Struhl K, Tora L. 2011. SAGA and ATAC histone acetyl transferase complexes regulate distinct sets of genes and ATAC defines a class of p300-independent enhancers. Mol Cell 44: 410–423.
    • (2011) Mol Cell , vol.44 , pp. 410-423
    • Krebs, A.R.1    Karmodiya, K.2    Lindahl-Allen, M.3    Struhl, K.4    Tora, L.5
  • 34
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
    • R25
    • Langmead B, Trapnell C, Pop M, Salzberg SL. 2009. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol 10: R25.
    • (2009) Genome Biol , vol.10
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 36
    • 66149127693 scopus 로고    scopus 로고
    • The Gcn5 bromodomain of the SAGA complex facilitates cooperative and cross-tail acetylation of nucleosomes
    • Li S, Shogren-Knaak MA. 2009. The Gcn5 bromodomain of the SAGA complex facilitates cooperative and cross-tail acetylation of nucleosomes. J Biol Chem 284: 9411–9417.
    • (2009) J Biol Chem , vol.284 , pp. 9411-9417
    • Li, S.1    Shogren-Knaak, M.A.2
  • 37
    • 77957551870 scopus 로고    scopus 로고
    • A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts
    • Li R, Liang J, Ni S, Zhou T, Qing X, Li H, He W, Chen J, Li F, Zhuang Q, et al. 2010. A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. Cell Stem Cell 7: 51–63.
    • (2010) Cell Stem Cell , vol.7 , pp. 51-63
    • Li, R.1    Liang, J.2    Ni, S.3    Zhou, T.4    Qing, X.5    Li, H.6    He, W.7    Chen, J.8    Li, F.9    Zhuang, Q.10
  • 38
    • 77955501968 scopus 로고    scopus 로고
    • Butyrate promotes induced pluripotent stem cell generation
    • Liang G, Taranova O, Xia K, Zhang Y. 2010. Butyrate promotes induced pluripotent stem cell generation. J Biol Chem 285: 25516–25521.
    • (2010) J Biol Chem , vol.285 , pp. 25516-25521
    • Liang, G.1    Taranova, O.2    Xia, K.3    Zhang, Y.4
  • 39
    • 34250676810 scopus 로고    scopus 로고
    • Developmental potential of Gcn5−/−embryonic stem cells in vivo and in vitro
    • Lin W, Srajer G, Evrard YA, Phan HM, Furuta Y, Dent SY. 2007. Developmental potential of Gcn5−/− embryonic stem cells in vivo and in vitro. Dev Dyn 236: 1547–1557.
    • (2007) Dev Dyn , vol.236 , pp. 1547-1557
    • Lin, W.1    Srajer, G.2    Evrard, Y.A.3    Phan, H.M.4    Furuta, Y.5    Dent, S.Y.6
  • 43
    • 84875160871 scopus 로고    scopus 로고
    • Reprogramming human fibroblasts to pluripotency using modified mRNA
    • Mandal PK, Rossi DJ. 2013. Reprogramming human fibroblasts to pluripotency using modified mRNA. Nat Protoc 8: 568–582.
    • (2013) Nat Protoc , vol.8 , pp. 568-582
    • Mandal, P.K.1    Rossi, D.J.2
  • 45
    • 0032508406 scopus 로고    scopus 로고
    • A human SPT3–TAFII31–GCN5–L acetylase complex distinct from transcription factor IID
    • Martinez E, Kundu TK, Fu J, Roeder RG. 1998. A human SPT3–TAFII31–GCN5–L acetylase complex distinct from transcription factor IID. J Biol Chem 273: 23781–23785.
    • (1998) J Biol Chem , vol.273 , pp. 23781-23785
    • Martinez, E.1    Kundu, T.K.2    Fu, J.3    Roeder, R.G.4
  • 47
    • 83455218560 scopus 로고    scopus 로고
    • Global epigenetic changes during somatic cell reprogramming to iPS cells
    • Mattout A, Biran A, Meshorer E. 2011. Global epigenetic changes during somatic cell reprogramming to iPS cells. J Mol Cell Biol 3: 341–350.
    • (2011) J Mol Cell Biol , vol.3 , pp. 341-350
    • Mattout, A.1    Biran, A.2    Meshorer, E.3
  • 48
    • 0032493894 scopus 로고    scopus 로고
    • The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins
    • McMahon SB, Van Buskirk HA, Dugan KA, Copeland TD, Cole MD. 1998. The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins. Cell 94: 363–374.
    • (1998) Cell , vol.94 , pp. 363-374
    • McMahon, S.B.1    Van Buskirk, H.A.2    Dugan, K.A.3    Copeland, T.D.4    Cole, M.D.5
  • 49
    • 0033970431 scopus 로고    scopus 로고
    • The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc
    • McMahon SB,Wood MA, Cole MD. 2000. The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc. Mol Cell Biol 20: 556–562.
    • (2000) Mol Cell Biol , vol.20 , pp. 556-562
    • McMahon, S.B.1    Wood, M.A.2    Cole, M.D.3
  • 50
    • 0038106229 scopus 로고    scopus 로고
    • Identification, expression, and tissue distribution of the three rat lysyl hydroxylase isoforms
    • Mercer DK, Nicol PF, Kimbembe C, Robins SP. 2003. Identification, expression, and tissue distribution of the three rat lysyl hydroxylase isoforms. Biochem Biophys Res Commun 307: 803–809.
    • (2003) Biochem Biophys Res Commun , vol.307 , pp. 803-809
    • Mercer, D.K.1    Nicol, P.F.2    Kimbembe, C.3    Robins, S.P.4
  • 52
    • 6344276685 scopus 로고    scopus 로고
    • Protocadherin FAT1 binds Ena/VASP proteins and is necessary for actin dynamics and cell polarization
    • Moeller MJ, Soofi A, Braun GS, Li X, Watzl C, Kriz W, Holzman LB. 2004. Protocadherin FAT1 binds Ena/VASP proteins and is necessary for actin dynamics and cell polarization. EMBO J 23: 3769–3779.
    • (2004) EMBO J , vol.23 , pp. 3769-3779
    • Moeller, M.J.1    Soofi, A.2    Braun, G.S.3    Li, X.4    Watzl, C.5    Kriz, W.6    Holzman, L.B.7
  • 56
    • 84887016186 scopus 로고    scopus 로고
    • Global splicing pattern reversion during somatic cell reprogramming
    • Ohta S, Nishida E, Yamanaka S, Yamamoto T. 2013. Global splicing pattern reversion during somatic cell reprogramming. Cell Rep 5: 357–366.
    • (2013) Cell Rep , vol.5 , pp. 357-366
    • Ohta, S.1    Nishida, E.2    Yamanaka, S.3    Yamamoto, T.4
  • 61
    • 77951770756 scopus 로고    scopus 로고
    • BEDTools: A flexible suite of utilities for comparing genomic features
    • Quinlan AR, Hall IM. 2010. BEDTools: a flexible suite of utilities for comparing genomic features. Bioinformatics 26: 841–842.
    • (2010) Bioinformatics , vol.26 , pp. 841-842
    • Quinlan, A.R.1    Hall, I.M.2
  • 63
    • 75249087100 scopus 로고    scopus 로고
    • EdgeR: A Bioconductor package for differential expression analysis of digital gene expression data
    • Robinson MD, McCarthy DJ, Smyth GK. 2010. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics 26: 139–140.
    • (2010) Bioinformatics , vol.26 , pp. 139-140
    • Robinson, M.D.1    McCarthy, D.J.2    Smyth, G.K.3
  • 67
    • 82955212911 scopus 로고    scopus 로고
    • A new chapter in the transcription SAGA
    • Samara NL, Wolberger C. 2011. A new chapter in the transcription SAGA. Curr Opin Struct Biol 21: 767–774.
    • (2011) Curr Opin Struct Biol , vol.21 , pp. 767-774
    • Samara, N.L.1    Wolberger, C.2
  • 69
  • 70
    • 84870058502 scopus 로고    scopus 로고
    • Facilitators and impediments of the pluripotency reprogramming factors’ initial engagement with the genome
    • Soufi A, Donahue G, Zaret KS. 2012. Facilitators and impediments of the pluripotency reprogramming factors’ initial engagement with the genome. Cell 151: 994–1004.
    • (2012) Cell , vol.151 , pp. 994-1004
    • Soufi, A.1    Donahue, G.2    Zaret, K.S.3
  • 71
    • 84858329099 scopus 로고    scopus 로고
    • ATAC-king the complexity of SAGA during evolution
    • Spedale G, Timmers HT, Pijnappel WW. 2012. ATAC-king the complexity of SAGA during evolution. Genes Dev 26: 527–541.
    • (2012) Genes Dev , vol.26 , pp. 527-541
    • Spedale, G.1    Timmers, H.T.2    Pijnappel, W.W.3
  • 73
  • 74
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S. 2006. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126: 663–676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 75
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: Discovering splice junctions with RNA-seq
    • Trapnell C, Pachter L, Salzberg SL. 2009. TopHat: discovering splice junctions with RNA-seq. Bioinformatics 25: 1105–1111.
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 79
    • 13444309266 scopus 로고    scopus 로고
    • Tissue-specific expression and regulation of the alternatively-spliced forms of lysyl hydroxylase 2 (LH2) in human kidney cells and skin fibroblasts
    • Walker LC, Overstreet MA, Yeowell HN. 2005. Tissue-specific expression and regulation of the alternatively-spliced forms of lysyl hydroxylase 2 (LH2) in human kidney cells and skin fibroblasts. Matrix Biol 23: 515–523.
    • (2005) Matrix Biol , vol.23 , pp. 515-523
    • Walker, L.C.1    Overstreet, M.A.2    Yeowell, H.N.3
  • 80
    • 0031036154 scopus 로고    scopus 로고
    • Histone acetyltransferase activity is conserved between yeast and human GCN5 and is required for complementation of growth and transcriptional activation
    • Wang L, Mizzen C, Ying C, Candau R, Barlev N, Brownell J, Allis CD, Berger SL. 1997. Histone acetyltransferase activity is conserved between yeast and human GCN5 and is required for complementation of growth and transcriptional activation. Mol Cell Biol 17: 519–527.
    • (1997) Mol Cell Biol , vol.17 , pp. 519-527
    • Wang, L.1    Mizzen, C.2    Ying, C.3    Candau, R.4    Barlev, N.5    Brownell, J.6    Allis, C.D.7    Berger, S.L.8
  • 83
    • 77950396799 scopus 로고    scopus 로고
    • Dynamic transcriptomes during neural differentiation of human embryonic stem cells revealed by short, long, and paired-end sequencing
    • Wu JQ, Habegger L, Noisa P, Szekely A, Qiu C, Hutchison S, Raha D, Egholm M, Lin H, Weissman S, et al. 2010. Dynamic transcriptomes during neural differentiation of human embryonic stem cells revealed by short, long, and paired-end sequencing. Proc Natl Acad Sci 107: 5254–5259.
    • (2010) Proc Natl Acad Sci , vol.107 , pp. 5254-5259
    • Wu, J.Q.1    Habegger, L.2    Noisa, P.3    Szekely, A.4    Qiu, C.5    Hutchison, S.6    Raha, D.7    Egholm, M.8    Lin, H.9    Weissman, S.10
  • 84
    • 0033623238 scopus 로고    scopus 로고
    • Loss of Gcn5l2 leads to increased apoptosis and mesodermal defects during mouse development
    • Xu W, Edmondson DG, Evrard YA, Wakamiya M, Behringer RR, Roth SY. 2000. Loss of Gcn5l2 leads to increased apoptosis and mesodermal defects during mouse development. Nat Genet 26: 229–232.
    • (2000) Nat Genet , vol.26 , pp. 229-232
    • Xu, W.1    Edmondson, D.G.2    Evrard, Y.A.3    Wakamiya, M.4    Behringer, R.R.5    Roth, S.Y.6
  • 87
    • 84903781415 scopus 로고    scopus 로고
    • MYC interacts with the human STAGA coactivator complex via multivalent contacts with the GCN5 and TRRAP subunits
    • Zhang N, Ichikawa W, Faiola F, Lo SY, Liu X, Martinez E. 2014. MYC interacts with the human STAGA coactivator complex via multivalent contacts with the GCN5 and TRRAP subunits. Biochim Biophys Acta 1839: 395–405.
    • (2014) Biochim Biophys Acta , vol.1839 , pp. 395-405
    • Zhang, N.1    Ichikawa, W.2    Faiola, F.3    Lo, S.Y.4    Liu, X.5    Martinez, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.