-
1
-
-
84875937513
-
Genetic susceptibility to SLE: Recent progress from GWAS
-
23395425
-
Cui Y, Sheng Y, Zhang X. Genetic susceptibility to SLE: recent progress from GWAS. Journal of autoimmunity. 2013;41:25-33. doi: 10.1016/j.jaut.2013.01.008 PMID: 23395425.
-
(2013)
Journal of autoimmunity.
, vol.41
, pp. 25-33
-
-
Cui, Y.1
Sheng, Y.2
Zhang, X.3
-
2
-
-
33745168605
-
Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication
-
16709748
-
Pisitkun P, Deane JA, Difilippantonio MJ, Tarasenko T, Satterthwaite AB, Bolland S. Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication. Science. 2006;312(5780):1669-72. doi: 10.1126/science.1124978 PMID: 16709748.
-
(2006)
Science
, vol.312
, Issue.5780
, pp. 1669-1672
-
-
Pisitkun, P.1
Deane, J.A.2
Difilippantonio, M.J.3
Tarasenko, T.4
Satterthwaite, A.B.5
Bolland, S.6
-
3
-
-
33745617886
-
A Tlr7 translocation accelerates systemic autoimmunity in murine lupus
-
16777955 PubMed Central PMCID: PMC1502563
-
Subramanian S, Tus K, Li QZ, Wang A, Tian XH, Zhou J, et al. A Tlr7 translocation accelerates systemic autoimmunity in murine lupus. Proceedings of the National Academy of Sciences of the United States of America. 2006;103(26):9970-5. doi: 10.1073/pnas.0603912103 PMID: 16777955; PubMed Central PMCID: PMC1502563.
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.26
, pp. 9970-9975
-
-
Subramanian, S.1
Tus, K.2
Li, Q.Z.3
Wang, A.4
Tian, X.H.5
Zhou, J.6
-
4
-
-
0018572881
-
AY chromosome associated factor in strain BXSB producing accelerated autoimmunity and lymphoproliferation
-
315777
-
Murphy ED, Roths JB. AY chromosome associated factor in strain BXSB producing accelerated autoimmunity and lymphoproliferation. Arthritis and rheumatism. 1979;22(11):1188-94. PMID: 315777.
-
(1979)
Arthritis and Rheumatism
, vol.22
, Issue.11
, pp. 1188-1194
-
-
Murphy, E.D.1
Roths, J.B.2
-
5
-
-
0006649662
-
-
Rose NR, Bigazzi PE, Warner NL, editors, New York: Elsevier/Holland
-
Murphy ED, Roths JB. The genetic control of autoimmune disease. In: Rose NR, Bigazzi PE, Warner NL, editors. New York: Elsevier/Holland; 1978. p. 207-21.
-
(1978)
The Genetic Control of Autoimmune Disease
, pp. 207-221
-
-
Murphy, E.D.1
Roths, J.B.2
-
6
-
-
0035945902
-
The immune response modifier resiquimod mimics CD40-induced B cell activation
-
11277614
-
Bishop GA, Ramirez LM, Baccam M, Busch LK, Pederson LK, Tomai MA. The immune response modifier resiquimod mimics CD40-induced B cell activation. Cellular immunology. 2001;208(1):9-17. doi: 10.1006/cimm.2001.1769 PMID: 11277614.
-
(2001)
Cellular Immunology
, vol.208
, Issue.1
, pp. 9-17
-
-
Bishop, G.A.1
Ramirez, L.M.2
Baccam, M.3
Busch, L.K.4
Pederson, L.K.5
Tomai, M.A.6
-
7
-
-
0036008014
-
Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
-
11812998
-
Hemmi H, Kaisho T, Takeuchi O, Sato S, Sanjo H, Hoshino K, et al. Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nature immunology. 2002;3(2):196-200. doi: 10.1038/ni758 PMID: 11812998.
-
(2002)
Nature Immunology
, vol.3
, Issue.2
, pp. 196-200
-
-
Hemmi, H.1
Kaisho, T.2
Takeuchi, O.3
Sato, S.4
Sanjo, H.5
Hoshino, K.6
-
8
-
-
17844380477
-
Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction
-
15815647
-
Honda K, Ohba Y, Yanai H, Negishi H, Mizutani T, Takaoka A, et al. Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction. Nature. 2005;434(7036):1035-40. doi: 10.1038/nature03547 PMID: 15815647.
-
(2005)
Nature
, vol.434
, Issue.7036
, pp. 1035-1040
-
-
Honda, K.1
Ohba, Y.2
Yanai, H.3
Negishi, H.4
Mizutani, T.5
Takaoka, A.6
-
9
-
-
60849107595
-
A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice
-
19164519 PubMed Central PMCID: PMC2635818
-
Bubier JA, Sproule TJ, Foreman O, Spolski R, Shaffer DJ, Morse HC3rd, et al. A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice. Proceedings of the National Academy of Sciences of the United States of America. 2009;106(5):1518-23. doi: 10.1073/pnas.0807309106 PMID: 19164519; PubMed Central PMCID: PMC2635818.
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, Issue.5
, pp. 1518-1523
-
-
Bubier, J.A.1
Sproule, T.J.2
Foreman, O.3
Spolski, R.4
Shaffer, D.J.5
Morse, H.C.6
-
10
-
-
80555154829
-
MHC class I family proteins retard systemic lupus erythematosus autoimmunity and B cell lymphomagenesis
-
21964024 PubMed Central PMCID: PMC3381364
-
McPhee CG, Sproule TJ, Shin DM, Bubier JA, Schott WH, Steinbuck MP, et al. MHC class I family proteins retard systemic lupus erythematosus autoimmunity and B cell lymphomagenesis. Journal of immunology. 2011;187(9):4695-704. doi: 10.4049/jimmunol.1101776 PMID: 21964024; PubMed Central PMCID: PMC3381364.
-
(2011)
Journal of Immunology
, vol.187
, Issue.9
, pp. 4695-4704
-
-
McPhee, C.G.1
Sproule, T.J.2
Shin, D.M.3
Bubier, J.A.4
Schott, W.H.5
Steinbuck, M.P.6
-
11
-
-
84886049045
-
IL-21 is a double-edged sword in the systemic lupus erythematosus-like disease of BXSB. Yaa mice
-
24078696 PubMed Central PMCID: PMC3807747
-
McPhee CG, Bubier JA, Sproule TJ, Park G, Steinbuck MP, Schott WH, et al. IL-21 is a double-edged sword in the systemic lupus erythematosus-like disease of BXSB. Yaa mice. Journal of immunology. 2013;191(9):4581-8. doi: 10.4049/jimmunol.1300439 PMID: 24078696; PubMed Central PMCID: PMC3807747.
-
(2013)
Journal of Immunology
, vol.191
, Issue.9
, pp. 4581-4588
-
-
McPhee, C.G.1
Bubier, J.A.2
Sproule, T.J.3
Park, G.4
Steinbuck, M.P.5
Schott, W.H.6
-
12
-
-
60549105041
-
The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+T cells
-
19139170 PubMed Central PMCID: PMC2626667
-
Dienz O, Eaton SM, Bond JP, Neveu W, Moquin D, Noubade R, et al. The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+T cells. The Journal of experimental medicine. 2009;206(1):69-78. doi: 10.1084/jem.20081571 PMID: 19139170; PubMed Central PMCID: PMC2626667.
-
(2009)
The Journal of Experimental Medicine
, vol.206
, Issue.1
, pp. 69-78
-
-
Dienz, O.1
Eaton, S.M.2
Bond, J.P.3
Neveu, W.4
Moquin, D.5
Noubade, R.6
-
13
-
-
84866355862
-
IL-6 triggers IL-21 production by human CD4+T cells to drive STAT3-dependent plasma cell differentiation in B cells
-
22491065 PubMed Central PMCID: PMC3396759
-
Diehl SA, Schmidlin H, Nagasawa M, Blom B, Spits H. IL-6 triggers IL-21 production by human CD4+T cells to drive STAT3-dependent plasma cell differentiation in B cells. Immunology and cell biology. 2012;90(8):802-11. doi: 10.1038/icb.2012.17 PMID: 22491065; PubMed Central PMCID: PMC3396759.
-
(2012)
Immunology and Cell Biology
, vol.90
, Issue.8
, pp. 802-811
-
-
Diehl, S.A.1
Schmidlin, H.2
Nagasawa, M.3
Blom, B.4
Spits, H.5
-
14
-
-
63849275584
-
Interleukin-6/STAT3 signaling regulates the ability of naive T cells to acquire B-cell help capacities
-
19020307 PubMed Central PMCID: PMC2656270
-
Eddahri F, Denanglaire S, Bureau F, Spolski R, Leonard WJ, Leo O, et al. Interleukin-6/STAT3 signaling regulates the ability of naive T cells to acquire B-cell help capacities. Blood. 2009;113(11):2426-33. doi: 10.1182/blood-2008-04-154682 PMID: 19020307; PubMed Central PMCID: PMC2656270.
-
(2009)
Blood
, vol.113
, Issue.11
, pp. 2426-2433
-
-
Eddahri, F.1
Denanglaire, S.2
Bureau, F.3
Spolski, R.4
Leonard, W.J.5
Leo, O.6
-
15
-
-
79952637807
-
IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation
-
21423809 PubMed Central PMCID: PMC3056724
-
Eto D, Lao C, Di Toro D, Barnett B, Escobar TC, Kageyama R, et al. IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation. PloSone. 2011;6(3):e17739. doi: 10.1371/journal.pone.0017739 PMID: 21423809; PubMed Central PMCID: PMC3056724.
-
(2011)
PloSone
, vol.6
, Issue.3
, pp. e17739
-
-
Eto, D.1
Lao, C.2
Di Toro, D.3
Barnett, B.4
Escobar, T.C.5
Kageyama, R.6
-
16
-
-
77956207524
-
In vivo regulation of Bcl6 and T follicular helper cell development
-
20519643 PubMed Central PMCID: PMC2891136
-
Poholek AC, Hansen K, Hernandez SG, Eto D, Chandele A, Weinstein JS, et al. In vivo regulation of Bcl6 and T follicular helper cell development. Journal of immunology. 2010;185(1):313-26. doi: 10. 4049/jimmunol.0904023 PMID: 20519643; PubMed Central PMCID: PMC2891136.
-
(2010)
Journal of Immunology
, vol.185
, Issue.1
, pp. 313-326
-
-
Poholek, A.C.1
Hansen, K.2
Hernandez, S.G.3
Eto, D.4
Chandele, A.5
Weinstein, J.S.6
-
17
-
-
84875417243
-
Cutting edge: STAT1 is required for IL-6-mediated Bcl6 induction for early follicular helper cell differentiation
-
23447690 PubMed Central PMCID: PMC3626564
-
Choi YS, Eto D, Yang JA, Lao C, Crotty S. Cutting edge: STAT1 is required for IL-6-mediated Bcl6 induction for early follicular helper cell differentiation. Journal of immunology. 2013;190(7):3049-53. doi: 10.4049/jimmunol.1203032 PMID: 23447690; PubMed Central PMCID: PMC3626564.
-
(2013)
Journal of Immunology
, vol.190
, Issue.7
, pp. 3049-3053
-
-
Choi, Y.S.1
Eto, D.2
Yang, J.A.3
Lao, C.4
Crotty, S.5
-
18
-
-
0025854604
-
Age-associated increase in interleukin6 in MRL/lprmice
-
2049341
-
Tang B, Matsuda T, Akira S, Nagata N, Ikehara S, Hirano T, et al. Age-associated increase in interleukin6 in MRL/lprmice. International immunology. 1991;3(3):273-8. PMID: 2049341.
-
(1991)
International Immunology
, vol.3
, Issue.3
, pp. 273-278
-
-
Tang, B.1
Matsuda, T.2
Akira, S.3
Nagata, N.4
Ikehara, S.5
Hirano, T.6
-
19
-
-
0026677851
-
Abnormal distribution of IL-6 receptor in aged MRL/lpr mice: Elevated expression on B cells and absence on CD4+ cells
-
1363056
-
Kobayashi I, Matsuda T, Saito T, Yasukawa K, Kikutani H, Hirano T, et al. Abnormal distribution of IL-6 receptor in aged MRL/lpr mice: elevated expression on B cells and absence on CD4+ cells. International immunology. 1992;4(12):1407-12. PMID: 1363056.
-
(1992)
International Immunology
, vol.4
, Issue.12
, pp. 1407-1412
-
-
Kobayashi, I.1
Matsuda, T.2
Saito, T.3
Yasukawa, K.4
Kikutani, H.5
Hirano, T.6
-
20
-
-
0027480306
-
Serum soluble interleukin-6 receptor in MRL/lpr mice is elevated with age and mediates the interleukin-6 signal
-
8477802
-
Suzuki H, Yasukawa K, Saito T, Narazaki M, Hasegawa A, Taga T, et al. Serum soluble interleukin-6 receptor in MRL/lpr mice is elevated with age and mediates the interleukin-6 signal. European journal of immunology. 1993;23(5):1078-82. doi: 10.1002/eji.1830230515 PMID: 8477802.
-
(1993)
European Journal of Immunology
, vol.23
, Issue.5
, pp. 1078-1082
-
-
Suzuki, H.1
Yasukawa, K.2
Saito, T.3
Narazaki, M.4
Hasegawa, A.5
Taga, T.6
-
21
-
-
0033808893
-
Cytokine production, serum levels and disease activity in systemic lupus erythematosus
-
11072595
-
Grondal G, Gunnarsson I, Ronnelid J, Rogberg S, Klareskog L, Lundberg I. Cytokine production, serum levels and disease activity in systemic lupus erythematosus. Clinical and experimental rheumatology. 2000;18(5):565-70. PMID: 11072595.
-
(2000)
Clinical and Experimental Rheumatology
, vol.18
, Issue.5
, pp. 565-570
-
-
Grondal, G.1
Gunnarsson, I.2
Ronnelid, J.3
Rogberg, S.4
Klareskog, L.5
Lundberg, I.6
-
22
-
-
0025990288
-
Elevated levels of endogenous IL-6 in systemic lupus erythematosus. A putative role in pathogenesis
-
2051017
-
Linker-Israeli M, Deans RJ, Wallace DJ, Prehn J, Ozeri-Chen T, Klinenberg JR. Elevated levels of endogenous IL-6 in systemic lupus erythematosus. A putative role in pathogenesis. Journal of immunology. 1991;147(1):117-23. PMID: 2051017.
-
(1991)
Journal of Immunology
, vol.147
, Issue.1
, pp. 117-123
-
-
Linker-Israeli, M.1
Deans, R.J.2
Wallace, D.J.3
Prehn, J.4
Ozeri-Chen, T.5
Klinenberg, J.R.6
-
23
-
-
0025541177
-
Possible role of IL-6 in pathogenesis of immune complex-mediated glomerulonephritis in NZB/W F1 mice: Induction of IgG class anti-DNA autoantibody production
-
2086490
-
Mihara M, Ohsugi Y. Possible role of IL-6 in pathogenesis of immune complex-mediated glomerulonephritis in NZB/W F1 mice: induction of IgG class anti-DNA autoantibody production. International archives of allergy and applied immunology. 1990;93(1):89-92. PMID: 2086490.
-
(1990)
International Archives of Allergy and Applied Immunology
, vol.93
, Issue.1
, pp. 89-92
-
-
Mihara, M.1
Ohsugi, Y.2
-
24
-
-
84895795419
-
A meta-analysis of the association of IL-6-174 G/C and -572 G/C polymorphisms with systemic lupus erythematosus risk
-
24013670
-
Yang Z, Liang Y, Qin B, Zhong R. A meta-analysis of the association of IL-6-174 G/C and -572 G/C polymorphisms with systemic lupus erythematosus risk. Rheumatology international. 2014;34(2):199-205. doi: 10.1007/s00296-013-2855-4 PMID: 24013670.
-
(2014)
Rheumatology International
, vol.34
, Issue.2
, pp. 199-205
-
-
Yang, Z.1
Liang, Y.2
Qin, B.3
Zhong, R.4
-
25
-
-
58149131467
-
Toll-like receptor 7-induced naive human B-cell differentiation and immunoglobulin production
-
18995892
-
Glaum MC, Narula S, Song D, Zheng Y, Anderson AL, Pletcher CH, et al. Toll-like receptor 7-induced naive human B-cell differentiation and immunoglobulin production. The Journal of allergy and clinical immunology. 2009;123(1):224-30e4. doi: 10.1016/j.jaci.2008.09.018 PMID: 18995892.
-
(2009)
The Journal of Allergy and Clinical Immunology
, vol.123
, Issue.1
, pp. 224-30e4
-
-
Glaum, M.C.1
Narula, S.2
Song, D.3
Zheng, Y.4
Anderson, A.L.5
Pletcher, C.H.6
-
26
-
-
42249098748
-
TLR7 and CD40 cooperate in IL-6 production via enhanced JNK and AP-1 activation
-
18228247 PubMed Central PMCID: PMC2951126
-
Van den Bush TJ, Bishop GA. TLR7 and CD40 cooperate in IL-6 production via enhanced JNK and AP-1 activation. European journal of immunology. 2008;38(2):400-9. doi: 10.1002/eji.200737602 PMID: 18228247; PubMed Central PMCID: PMC2951126.
-
(2008)
European Journal of Immunology
, vol.38
, Issue.2
, pp. 400-409
-
-
Van Den Bush, T.J.1
Bishop, G.A.2
-
27
-
-
0026092379
-
In vitro regulation of B cell differentiation by interleukin-6 and soluble CD23 in systemic lupus erythematosus B cell subpopulations and antigeninduced normal B cells
-
1825912
-
Klashman DJ, Martin RA, Martinez-Maza O, Stevens RH. In vitro regulation of B cell differentiation by interleukin-6 and soluble CD23 in systemic lupus erythematosus B cell subpopulations and antigeninduced normal B cells. Arthritis and rheumatism. 1991;34(3):276-86. PMID: 1825912.
-
(1991)
Arthritis and Rheumatism
, vol.34
, Issue.3
, pp. 276-286
-
-
Klashman, D.J.1
Martin, R.A.2
Martinez-Maza, O.3
Stevens, R.H.4
-
28
-
-
70349664422
-
Toll-like receptors-sentries in the B-cell response
-
20067531 PubMed Central PMCID: PMC2770679
-
Bekeredjian-Ding I, Jego G. Toll-like receptors-sentries in the B-cell response. Immunology. 2009;128(3):311-23. doi: 10.1111/j.1365-2567.2009.03173.x PMID: 20067531; PubMed Central PMCID: PMC2770679.
-
(2009)
Immunology
, vol.128
, Issue.3
, pp. 311-323
-
-
Bekeredjian-Ding, I.1
Jego, G.2
-
29
-
-
34250192856
-
TLR agonists selectively promote terminal plasma cell differentiation of B cell subsets specialized in thymus-independent responses
-
17548615
-
Genestier L, Taillardet M, Mondiere P, Gheit H, Bella C, Defrance T. TLR agonists selectively promote terminal plasma cell differentiation of B cell subsets specialized in thymus-independent responses. Journal of immunology. 2007;178(12):7779-86. PMID: 17548615.
-
(2007)
Journal of Immunology
, vol.178
, Issue.12
, pp. 7779-7786
-
-
Genestier, L.1
Taillardet, M.2
Mondiere, P.3
Gheit, H.4
Bella, C.5
Defrance, T.6
-
30
-
-
0037061453
-
Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
-
11948342
-
Leadbetter EA, Rifkin IR, Hohlbaum AM, Beaudette BC, Shlomchik MJ, Marshak-Rothstein A. Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. Nature. 2002;416(6881):603-7. doi: 10.1038/416603a PMID: 11948342.
-
(2002)
Nature
, vol.416
, Issue.6881
, pp. 603-607
-
-
Leadbetter, E.A.1
Rifkin, I.R.2
Hohlbaum, A.M.3
Beaudette, B.C.4
Shlomchik, M.J.5
Marshak-Rothstein, A.6
-
31
-
-
33646027625
-
Type IIFN receptor signals directly stimulate local B cells early following influenza virus infection
-
16547272
-
Coro ES, Chang WL, Baumgarth N. Type IIFN receptor signals directly stimulate local B cells early following influenza virus infection. Journal of immunology. 2006;176(7):4343-51. PMID: 16547272.
-
(2006)
Journal of Immunology
, vol.176
, Issue.7
, pp. 4343-4351
-
-
Coro, E.S.1
Chang, W.L.2
Baumgarth, N.3
-
32
-
-
0028070714
-
Functional role of type I and type II interferons in antiviral defense
-
8009221
-
Muller U, Steinhoff U, Reis LF, Hemmi S, Pavlovic J, Zinkernagel RM, et al. Functional role of type I and type II interferons in antiviral defense. Science. 1994;264(5167):1918-21. PMID: 8009221.
-
(1994)
Science
, vol.264
, Issue.5167
, pp. 1918-1921
-
-
Muller, U.1
Steinhoff, U.2
Reis, L.F.3
Hemmi, S.4
Pavlovic, J.5
Zinkernagel, R.M.6
-
33
-
-
76249088375
-
B7-1/2 (CD80/CD86) direct signaling to B cells enhances IgG secretion
-
19933871 PubMed Central PMCID: PMC2795108
-
Rau FC, Dieter J, Luo Z, Priest SO, Baumgarth N. B7-1/2 (CD80/CD86) direct signaling to B cells enhances IgG secretion. Journal of immunology. 2009;183(12):7661-71. doi: 10.4049/jimmunol. 0803783 PMID: 19933871; PubMed Central PMCID: PMC2795108.
-
(2009)
Journal of Immunology
, vol.183
, Issue.12
, pp. 7661-7671
-
-
Rau, F.C.1
Dieter, J.2
Luo, Z.3
Priest, S.O.4
Baumgarth, N.5
-
34
-
-
0344665750
-
Microarray analysis of interferon-regulated genes in SLE
-
14984025
-
Crow MK, Kirou KA, Wohlgemuth J. Microarray analysis of interferon-regulated genes in SLE. Autoimmunity. 2003;36(8):481-90. PMID: 14984025.
-
(2003)
Autoimmunity
, vol.36
, Issue.8
, pp. 481-490
-
-
Crow, M.K.1
Kirou, K.A.2
Wohlgemuth, J.3
-
35
-
-
0344492212
-
Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus
-
12604793 PubMed Central PMCID: PMC151388
-
Baechler EC, Batliwalla FM, Karypis G, Gaffney PM, Ortmann WA, Espe KJ, et al. Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus. Proceedings of the National Academy of Sciences of the United States of America. 2003;100(5):2610-5. doi: 10.1073/pnas.0337679100 PMID: 12604793; PubMed Central PMCID: PMC151388.
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.5
, pp. 2610-2615
-
-
Baechler, E.C.1
Batliwalla, F.M.2
Karypis, G.3
Gaffney, P.M.4
Ortmann, W.A.5
Espe, K.J.6
-
36
-
-
79953161285
-
The type I interferon system in the development of lupus
-
21292501
-
Ronnblom L, Alm GV, Eloranta ML. The type I interferon system in the development of lupus. Seminars in immunology. 2011;23(2):113-21. doi: 10.1016/j.smim.2011.01.009 PMID: 21292501.
-
(2011)
Seminars in Immunology
, vol.23
, Issue.2
, pp. 113-121
-
-
Ronnblom, L.1
Alm, G.V.2
Eloranta, M.L.3
-
37
-
-
0037371122
-
The Yaa mutation promoting murine lupus causes defective development of marginal zone B cells
-
12594250
-
Amano H, Amano E, Moll T, Marinkovic D, Ibnou-Zekri N, Martinez-Soria E, et al. The Yaa mutation promoting murine lupus causes defective development of marginal zone B cells. Journal of immunology. 2003;170(5):2293-301. PMID: 12594250.
-
(2003)
Journal of Immunology
, vol.170
, Issue.5
, pp. 2293-2301
-
-
Amano, H.1
Amano, E.2
Moll, T.3
Marinkovic, D.4
Ibnou-Zekri, N.5
Martinez-Soria, E.6
-
38
-
-
0021346009
-
Monocytosis in the BXSB model for systemic lupus erythematosus
-
6363600 PubMed Central PMCID: PMC2187231
-
Wofsy D, Kerger CE, Seaman WE. Monocytosis in the BXSB model for systemic lupus erythematosus. The Journal of experimental medicine. 1984;159(2):629-34. PMID: 6363600; PubMed Central PMCID: PMC2187231.
-
(1984)
The Journal of Experimental Medicine
, vol.159
, Issue.2
, pp. 629-634
-
-
Wofsy, D.1
Kerger, C.E.2
Seaman, W.E.3
-
39
-
-
36949006089
-
Monocytosis in BXSB mice is due to epistasis between Yaa and the telomeric region of chromosome 1 but does not drive the disease process
-
17728791
-
Rogers NJ, Gabriel L, Nunes CT, Rose SJ, Thiruudaian V, Boyle J, et al. Monocytosis in BXSB mice is due to epistasis between Yaa and the telomeric region of chromosome 1 but does not drive the disease process. Genes and immunity. 2007;8(8):619-27. doi: 10.1038/sj.gene.6364424 PMID: 17728791.
-
(2007)
Genes and Immunity
, vol.8
, Issue.8
, pp. 619-627
-
-
Rogers, N.J.1
Gabriel, L.2
Nunes, C.T.3
Rose, S.J.4
Thiruudaian, V.5
Boyle, J.6
-
40
-
-
0026028365
-
An autosomal recessive gene that delays expression of lupus in BXSB mice
-
1991974
-
Kofler R, McConahey PJ, Duchosal MA, Balderas RS, Theofilopoulos AN, Dixon FJ. An autosomal recessive gene that delays expression of lupus in BXSB mice. Journal of immunology. 1991;146(4):1375-9. PMID: 1991974.
-
(1991)
Journal of Immunology
, vol.146
, Issue.4
, pp. 1375-1379
-
-
Kofler, R.1
McConahey, P.J.2
Duchosal, M.A.3
Balderas, R.S.4
Theofilopoulos, A.N.5
Dixon, F.J.6
-
41
-
-
45149123617
-
Development and characterization of IL-21-producing CD4+ T cells
-
18474630 PubMed Central PMCID: PMC2413034
-
Suto A, Kashiwakuma D, Kagami S, Hirose K, Watanabe N, Yokote K, et al. Development and characterization of IL-21-producing CD4+ T cells. The Journal of experimental medicine. 2008;205(6):1369-79. doi: 10.1084/jem.20072057 PMID: 18474630; PubMed Central PMCID: PMC2413034.
-
(2008)
The Journal of Experimental Medicine
, vol.205
, Issue.6
, pp. 1369-1379
-
-
Suto, A.1
Kashiwakuma, D.2
Kagami, S.3
Hirose, K.4
Watanabe, N.5
Yokote, K.6
-
42
-
-
79952675131
-
Follicular helper CD4T cells (TFH)
-
21314428
-
Crotty S. Follicular helper CD4T cells (TFH). Annual review of immunology. 2011;29:621-63. doi: 10. 1146/annurev-immunol-031210-101400 PMID: 21314428.
-
(2011)
Annual Review of Immunology
, vol.29
, pp. 621-663
-
-
Crotty, S.1
-
43
-
-
0027461333
-
Macrophage depletion decreases IgG anti-DNA in cultures from (NZBx NZW) F1 spleen cells by eliminating the main source of IL-6
-
8428389 PubMed Central PMCID: PMC1554691
-
Alarcon-Riquelme ME, Moller G, Fernandez C. Macrophage depletion decreases IgG anti-DNA in cultures from (NZBx NZW) F1 spleen cells by eliminating the main source of IL-6. Clinical and experimental immunology. 1993;91(2):220-5. PMID: 8428389; PubMed Central PMCID: PMC1554691.
-
(1993)
Clinical and Experimental Immunology
, vol.91
, Issue.2
, pp. 220-225
-
-
Alarcon-Riquelme, M.E.1
Moller, G.2
Fernandez, C.3
-
44
-
-
0032494191
-
Interleukin 6 dependence of anti-DNA antibody production: Evidence for two pathways of autoantibody formation in pristane-induced lupus
-
9730900 PubMed Central PMCID: PMC2213386
-
Richards HB, Satoh M, Shaw M, Libert C, Poli V, Reeves WH. Interleukin 6 dependence of anti-DNA antibody production: evidence for two pathways of autoantibody formation in pristane-induced lupus. The Journal of experimental medicine. 1998;188(5):985-90. PMID: 9730900; PubMed Central PMCID: PMC2213386.
-
(1998)
The Journal of Experimental Medicine
, vol.188
, Issue.5
, pp. 985-990
-
-
Richards, H.B.1
Satoh, M.2
Shaw, M.3
Libert, C.4
Poli, V.5
Reeves, W.H.6
-
45
-
-
0027930909
-
Interleukin 6 promotes murine lupus in NZB/NZW F1 mice
-
8040314 PubMed Central PMCID: PMC296134
-
Finck BK, Chan B, Wofsy D. Interleukin 6 promotes murine lupus in NZB/NZW F1 mice. The Journal of clinical investigation. 1994;94(2):585-91. doi: 10.1172/JCI117373 PMID: 8040314; PubMed Central PMCID: PMC296134.
-
(1994)
The Journal of Clinical Investigation
, vol.94
, Issue.2
, pp. 585-591
-
-
Finck, B.K.1
Chan, B.2
Wofsy, D.3
-
46
-
-
0024374992
-
Heterogeneity of B cell responsiveness to interleukin 4, interleukin 6 and low molecular weight B cell growth factor in discrete stages of B cell activation in patients with systemic lupus erythematosus
-
2788539 PubMed Central PMCID: PMC1541934
-
Kitani A, Hara M, Hirose T, Norioka K, Harigai M, Hirose W, et al. Heterogeneity of B cell responsiveness to interleukin 4, interleukin 6 and low molecular weight B cell growth factor in discrete stages of B cell activation in patients with systemic lupus erythematosus. Clinical and experimental immunology. 1989;77(1):31-6. PMID: 2788539; PubMed Central PMCID: PMC1541934.
-
(1989)
Clinical and Experimental Immunology
, vol.77
, Issue.1
, pp. 31-36
-
-
Kitani, A.1
Hara, M.2
Hirose, T.3
Norioka, K.4
Harigai, M.5
Hirose, W.6
-
47
-
-
0027376265
-
Constitutive expression of IL-6 receptors and their role in the excessive B cell function in patients with systemic lupus erythematosus
-
8245483
-
Nagafuchi H, Suzuki N, Mizushima Y, Sakane T. Constitutive expression of IL-6 receptors and their role in the excessive B cell function in patients with systemic lupus erythematosus. Journal of immunology. 1993;151(11):6525-34. PMID: 8245483.
-
(1993)
Journal of Immunology
, vol.151
, Issue.11
, pp. 6525-6534
-
-
Nagafuchi, H.1
Suzuki, N.2
Mizushima, Y.3
Sakane, T.4
-
48
-
-
27744444832
-
RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement
-
16260486 PubMed Central PMCID: PMC2213226
-
Lau CM, Broughton C, Tabor AS, Akira S, Flavell RA, Mamula MJ, et al. RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement. The Journal of experimental medicine. 2005;202(9):1171-7. doi: 10.1084/jem.20050630 PMID: 16260486; PubMed Central PMCID: PMC2213226.
-
(2005)
The Journal of Experimental Medicine
, vol.202
, Issue.9
, pp. 1171-1177
-
-
Lau, C.M.1
Broughton, C.2
Tabor, A.S.3
Akira, S.4
Flavell, R.A.5
Mamula, M.J.6
-
49
-
-
36848999463
-
Nucleic acid recognizing Toll-like receptors and autoimmunity
-
18060756
-
von Landenberg P, Bauer S. Nucleic acid recognizing Toll-like receptors and autoimmunity. Current opinion in immunology. 2007;19(6):606-10. doi: 10.1016/j.coi.2007.10.004 PMID: 18060756.
-
(2007)
Current Opinion in Immunology
, vol.19
, Issue.6
, pp. 606-610
-
-
Von Landenberg, P.1
Bauer, S.2
-
50
-
-
36048962438
-
Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation
-
17997333 PubMed Central PMCID: PMC2706502
-
Deane JA, Pisitkun P, Barrett RS, Feigenbaum L, Town T, Ward JM, et al. Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation. Immunity. 2007;27(5):801-10. doi: 10.1016/j.immuni.2007.09.009 PMID: 17997333; PubMed Central PMCID: PMC2706502.
-
(2007)
Immunity
, vol.27
, Issue.5
, pp. 801-810
-
-
Deane, J.A.1
Pisitkun, P.2
Barrett, R.S.3
Feigenbaum, L.4
Town, T.5
Ward, J.M.6
-
51
-
-
50549086761
-
Yaa autoimmune phenotypes are conferred by overexpression of TLR7
-
18521959 PubMed Central PMCID: PMC2993003
-
Fairhurst AM, Hwang SH, Wang A, Tian XH, Boudreaux C, Zhou XJ, et al. Yaa autoimmune phenotypes are conferred by overexpression of TLR7. European journal of immunology. 2008;38(7):1971-8. doi: 10.1002/eji.200838138 PMID: 18521959; PubMed Central PMCID: PMC2993003.
-
(2008)
European Journal of Immunology
, vol.38
, Issue.7
, pp. 1971-1978
-
-
Fairhurst, A.M.1
Hwang, S.H.2
Wang, A.3
Tian, X.H.4
Boudreaux, C.5
Zhou, X.J.6
-
52
-
-
49049120579
-
Evidence for genes in addition to Tlr7 in the Yaa translocation linked with acceleration of systemic lupus erythematosus
-
18606711
-
Santiago-Raber ML, Kikuchi S, Borel P, Uematsu S, Akira S, Kotzin BL, et al. Evidence for genes in addition to Tlr7 in the Yaa translocation linked with acceleration of systemic lupus erythematosus. Journal of immunology. 2008;181(2):1556-62. PMID: 18606711.
-
(2008)
Journal of Immunology
, vol.181
, Issue.2
, pp. 1556-1562
-
-
Santiago-Raber, M.L.1
Kikuchi, S.2
Borel, P.3
Uematsu, S.4
Akira, S.5
Kotzin, B.L.6
-
53
-
-
77957673544
-
Sex-specific association of X-linked Tolllike receptor 7 (TLR7) with male systemic lupus erythematosus
-
20733074 PubMed Central PMCID: PMC2936646
-
Shen N, Fu Q, Deng Y, Qian X, Zhao J, Kaufman KM, et al. Sex-specific association of X-linked Tolllike receptor 7 (TLR7) with male systemic lupus erythematosus. Proceedings of the National Academy of Sciences of the United States of America. 2010;107(36):15838-43. doi: 10.1073/pnas.1001337107 PMID: 20733074; PubMed Central PMCID: PMC2936646.
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, Issue.36
, pp. 15838-15843
-
-
Shen, N.1
Fu, Q.2
Deng, Y.3
Qian, X.4
Zhao, J.5
Kaufman, K.M.6
-
54
-
-
0036206908
-
IFN-alpha/betaenhances BCR-dependent B cell responses
-
11934877
-
Braun D, Caramalho I, Demengeot J. IFN-alpha/betaenhances BCR-dependent B cell responses. International immunology. 2002;14(4):411-9. PMID: 11934877.
-
(2002)
International Immunology
, vol.14
, Issue.4
, pp. 411-419
-
-
Braun, D.1
Caramalho, I.2
Demengeot, J.3
-
55
-
-
0035030376
-
Type i interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo
-
11336691
-
Le Bon A, Schiavoni G, D'Agostino G, Gresser I, Belardelli F, Tough DF. Type i interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo. Immunity. 2001;14(4):461-70. PMID: 11336691.
-
(2001)
Immunity
, vol.14
, Issue.4
, pp. 461-470
-
-
Le Bon, A.1
Schiavoni, G.2
D'Agostino, G.3
Gresser, I.4
Belardelli, F.5
Tough, D.F.6
-
56
-
-
0037451124
-
Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice
-
12642605 PubMed Central PMCID: PMC2193854
-
Santiago-Raber ML, Baccala R, Haraldsson KM, Choubey D, Stewart TA, Kono DH, et al. Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice. The Journal of experimental medicine. 2003;197(6):777-88. doi: 10.1084/jem.20021996 PMID: 12642605; PubMed Central PMCID: PMC2193854.
-
(2003)
The Journal of Experimental Medicine
, vol.197
, Issue.6
, pp. 777-788
-
-
Santiago-Raber, M.L.1
Baccala, R.2
Haraldsson, K.M.3
Choubey, D.4
Stewart, T.A.5
Kono, D.H.6
-
57
-
-
69249101229
-
Bcl6 mediates the development of T follicular helper cells
-
19628815 PubMed Central PMCID: PMC2857334
-
Nurieva RI, Chung Y, Martinez GJ, Yang XO, Tanaka S, Matskevitch TD, et al. Bcl6 mediates the development of T follicular helper cells. Science. 2009;325(5943):1001-5. doi: 10.1126/science.1176676 PMID: 19628815; PubMed Central PMCID: PMC2857334.
-
(2009)
Science
, vol.325
, Issue.5943
, pp. 1001-1005
-
-
Nurieva, R.I.1
Chung, Y.2
Martinez, G.J.3
Yang, X.O.4
Tanaka, S.5
Matskevitch, T.D.6
-
58
-
-
70450265288
-
Early commitment of naive human CD4 (+) T cells to the T follicular helper (T (FH)) cell lineage is induced by IL-12
-
19721453
-
Ma CS, Suryani S, Avery DT, Chan A, Nanan R, Santner-Nanan B, et al. Early commitment of naive human CD4 (+) T cells to the T follicular helper (T (FH)) cell lineage is induced by IL-12. Immunology and cell biology. 2009;87(8):590-600. doi: 10.1038/icb.2009.64 PMID: 19721453.
-
(2009)
Immunology and Cell Biology
, vol.87
, Issue.8
, pp. 590-600
-
-
Ma, C.S.1
Suryani, S.2
Avery, D.T.3
Chan, A.4
Nanan, R.5
Santner-Nanan, B.6
-
59
-
-
75749113331
-
Tocilizumab in systemic lupus erythematosus: Data on safety, preliminary efficacy, and impact on circulating plasma cells from an open-label phase I dosage-escalation study
-
20112381 PubMed Central PMCID: PMC3057537
-
Illei GG, Shirota Y, Yarboro CH, Daruwalla J, Tackey E, Takada K, et al. Tocilizumab in systemic lupus erythematosus: data on safety, preliminary efficacy, and impact on circulating plasma cells from an open-label phase I dosage-escalation study. Arthritis and rheumatism. 2010;62(2):542-52. doi: 10. 1002/art.27221 PMID: 20112381; PubMed Central PMCID: PMC3057537.
-
(2010)
Arthritis and Rheumatism
, vol.62
, Issue.2
, pp. 542-552
-
-
Illei, G.G.1
Shirota, Y.2
Yarboro, C.H.3
Daruwalla, J.4
Tackey, E.5
Takada, K.6
-
60
-
-
84885153193
-
Phase I, randomized, double-blind, placebo-controlled, multiple intravenous, dose-ascending study of sirukumabin cutaneous or systemic lupus erythematosus
-
23896980
-
Szepietowski JC, Nilganuwong S, Wozniacka A, Kuhn A, Nyberg F, van Vollenhoven RF, et al. Phase I, randomized, double-blind, placebo-controlled, multiple intravenous, dose-ascending study of sirukumabin cutaneous or systemic lupus erythematosus. Arthritis and rheumatism. 2013;65(10):2661-71. doi: 10.1002/art.38091 PMID: 23896980.
-
(2013)
Arthritis and Rheumatism
, vol.65
, Issue.10
, pp. 2661-2671
-
-
Szepietowski, J.C.1
Nilganuwong, S.2
Wozniacka, A.3
Kuhn, A.4
Nyberg, F.5
Van Vollenhoven, R.F.6
|