Porphyromonas gingivalis outer membrane vesicles induce selective tumor necrosis factor tolerance in a Toll-like receptor 4- and mTOR-dependent manner

Infection and Immunity

Volumn 84, Issue 4, 2016, Pages 1194-1204

  Waller, Tobias ^a   Kesper, Laura ^a   Hirschfeld, Josefine ^a   Dommisch, Henrik ^a,b   Kölpin, Johanna ^a   Oldenburg, Johannes ^c   Uebele, Julia ^a,d   Hoerauf, Achim ^a   Deschner, James ^a   Jepsen, Sören ^a   Bekeredjian Ding, Isabelle ^a,d  

^a UNIVERSITY HOSPITAL BONN   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c UNIVERSITY OF BONN   (Germany)

^d PAUL EHRLICH INSTITUT   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; CHLOROQUINE; CYTOCHALASIN B; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 12P40; INTERLEUKIN 1BETA; INTERLEUKIN 8; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; RAPAMYCIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR; LIPOPOLYSACCHARIDE; MTOR PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE; TLR4 PROTEIN, HUMAN;

ANTIGEN RECOGNITION; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; HUMAN; HUMAN CELL; IMMUNE EVASION; IMMUNE RESPONSE; INNATE IMMUNITY; MEMBRANE VESICLE; MONOCYTE; OUTER MEMBRANE VESICLE; PORPHYROMONAS GINGIVALIS; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; CELL MEMBRANE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; METABOLISM; PHYSIOLOGY;

CELL MEMBRANE; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; LIPOPOLYSACCHARIDES; MONOCYTES; PORPHYROMONAS GINGIVALIS; TOLL-LIKE RECEPTOR 4; TOR SERINE-THREONINE KINASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84962850730     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.01390-15     Document Type: Article

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