Notch controls the survival of memory CD4+ T cells by regulating glucose uptake

Nature Medicine

Volumn 21, Issue 1, 2015, Pages 55-61

  Maekawa, Yoichi ^a,d   Ishifune, Chieko ^a   Tsukumo, Shin Ichi ^a   Hozumi, Katsuto ^b   Yagita, Hideo ^c   Yasutomo, Koji ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c JUNTENDO UNIVERSITY   (Japan)

^d GIFU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA SECRETASE INHIBITOR; GLUCOSE; GLUCOSE TRANSPORTER 1; IMMUNOGLOBULIN J RECOMBINATION SIGNAL SEQUENCE BINDING PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; NOTCH RECEPTOR; PROTEIN KINASE B; STAT5 PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; ONCOPROTEIN; RBPJ PROTEIN, MOUSE; SLC2A1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CELL SURVIVAL; CONTROLLED STUDY; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; FEMALE; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SPLEEN CELL; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; DEFICIENCY; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM;

MUS;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; GLUCOSE; GLUCOSE TRANSPORTER TYPE 1; HUMANS; IMMUNOGLOBULIN J RECOMBINATION SIGNAL SEQUENCE-BINDING PROTEIN; MICE; ONCOGENE PROTEIN V-AKT; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

EID: 84925284022     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3758     Document Type: Article

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